1.The Effect of Rauwolfia Serpentina on the Retinal Arterial Blood Pressure in Hypertensive Patients.
Journal of the Korean Ophthalmological Society 1959;2(1):45-49
The diastolic retinal arterial blood pressure was measured by Ophthalmodynamometer in 15 patients of essential hypertension before and after the administration of Raudixin three times a days. The follow up period was 4 to 70 days. The average fall of the systolic brachial blood pressure was 38.1 mmHg(from 174.6 to 136.5 mmHg) 19 days after the treatment, whereas the average fall of the diastolic brachial blood pressure was 19.6 mmHg (from 166.6 to 94.7 mmHg) 24 days after treatment. A positive correlation was demonstrated between the retinal and brachial diastolic blood pressures prior to the treatment. The diastolic brachial blood pressure showed its fall only 15 days after treatment, the average fall being 17.1 mmHg. During this period of time, the average fall of the diastolic retinal arterial pressure was 10.2 mmHg. In 6 cases, the retinal arterial pressure didn't fall back to the normal valures and in 5 cases of Keith-Wagener group II, the retinal arterial pressure remained unchanged in spite of the treatment. The percentage ratio of the retinal to the brachial diastolic blood pressure remained stationary in 3 cases, rose in 4 cases. The number of cases which show fall in this ratio gradually increased and about 80% of the cases demonstrated definite fall one month after treatment. The retinal arterial pressure remained stationary during 2 weeks after treatment in 60% of the cases. The significant lowering of the retinal arterial blood pressure was observed only one month after treatment in the majority of cases. The retinal arterial pressure fell below normal range in no case.
Arterial Pressure*
;
Blood Pressure
;
Follow-Up Studies
;
Humans
;
Hypertension
;
Rauwolfia*
;
Reference Values
;
Retinaldehyde*
2.Endoscopic Posterior Cruciate Ligament Reconstruction Using a Quadrupled Hamstring Graft and Endobutton(r): Preliminary Report of a New Technique.
Kwang Won LEE ; Young Wan KIM ; Won Sik CHOY
The Journal of the Korean Orthopaedic Association 1998;33(6):1521-1529
We present our technique for reconstruction of the posterior cruciate ligament (PCL) using the quadrupled hamstring tendons with EndoButton(Acufex Microsurgical, Mansfield, MA). This paper describes the surgical technique of the procedures and reports the preliminary results in 10 patients with a more than 12 months follow-up. There were 8 males and 2 females ranging in age from 17 to 37 years (average 25 years). The average time from injury to operation was 3 weeks (range; 2 weeks to 4 weeks). Of ten patients, 6 were classified as an isolated tear, 2 were associated with lateral collateral ligament tears. A torn meniscus was present in 2 cases. We used one-incision technique. The results of these PCL reconstructions with a minimum follow-up of 12 months are as follows. Patients were evaluated preand postoperatively using the Lysholm, and Hospital for Special Surgery Knee ligament rating scales. Average knee ligament evaluation scores were Lysholm preoperative 48, postoperative 87.6; and Hospital for Special Surgery preoperatively 33.5, postoperative 88.8. We chose the semitendinosus and gracilis tendons with EndoButton fixation for PCL reconstruction for specific reasons: (1) No injury to the extensor mechanism and (2) Easy passage of the graft through the tibial tunnel. (3) The problem about the screw and patellar bone-tendon-bone can be resolved. (4) It preserves intact meniscofemoral ligament, some intact fibers of PCL bundle. (5) When rupture of the PCL is associated with ACL tear, each ligament should be reconstructed. In such a case, we preserve patellar tendon for reconstruction of the ACL, The technique presented here is not applicable to all individuals requiring PCL reconstruction but does provide significant advantages to those patients for whom it is utilized. Although the clinical results are very promising at this length of follow up, long-term study is required to evaluate our PCL reconstruction procedure more precisely.
Female
;
Follow-Up Studies
;
Humans
;
Knee
;
Lateral Ligament, Ankle
;
Ligaments
;
Male
;
Patellar Ligament
;
Posterior Cruciate Ligament*
;
Rupture
;
Tendons
;
Transplants*
;
Weights and Measures
3.Modular Hemiarthroplasty for the Treatment of Complex Fractures of the Proximal Humerus.
Kwang Won LEE ; Kyou Hyeun KIM ; Jong Hyeun PARK ; In Sik HWANG ; Won Sik CHOY
The Journal of the Korean Orthopaedic Association 1998;33(3):515-521
From 1993 to 1996, we have used a new modular shoulder prosthesis for the treatment of acute complex fracture of the proximal humerus. The purpose of this study is to evaluate function, pain relief, and patient satisfaction after moduiar hemiarthroplasty for proximal humerus fractures. The stucly included 12 patients (J2 shoulders) with an average age of 68.5 years (range, 60 to 84 years). According to the Neer classification system, there were 3 four-part fracture-dislocations, 5 four-part fractures, 3 three-part fractures, and #I head splitting fracture. 'fhe hemiarthroplasty was pert'ormed at an average of 4 days (range, 3 to 10 days) following injury. Deltopectoral approach was used in all patients, and the prostheses were implanted with cement in ten cases. Follow-up evaluation, at an average of 32 months post-surgery, included clinical and radio- graphic examination. Active forward elevation averaged 120 degrees; external rotation, 35 degrees; and internal rotation, to the first lumbar vertebra. All of patients, except two who had poor results, were graded as good or excellent according to UCLA shoulder rating scale. Complications consisted of one tuberosity dispiacement, one peri-operative death and one loosening of uncemented humeral prosthesis. We concluded that Modular hemiarthroplasty for acute complex fracture of the proximal humerus especially in severely osteoporotic elderly patients facilitated the restoration of humeral length, anatomic repositioning of tuberosities, and precise soft tissue balance, thereby allowing earliermotion to prevent the developement of painful shoulder stiffness.
Aged
;
Classification
;
Follow-Up Studies
;
Head
;
Hemiarthroplasty*
;
Humans
;
Humerus*
;
Patient Satisfaction
;
Prostheses and Implants
;
Shoulder
;
Spine
4.Solitary Bone Cyst of the Capitate: A Case Report
Yung Sik YANG ; Won Gap LEE ; Chung Surk LEE
The Journal of the Korean Orthopaedic Association 1980;15(2):366-369
Solitary bone cyst are usually found in the juxta-epiphyseal region of metaphysis of long bones of children. They are rarely seen in non-tubular bones. The following case describes what we believe to be a solitary cyst of the capitate. Cyst was treated by radical curettage and packing with autogenous iliac bone. The most recent evaluation 7 months after surgery showed no discomfort.
Bone Cysts
;
Child
;
Curettage
;
Humans
5.A Cases of Primary Cutaneous Cryptococcosis.
Sik CHOI ; Seung Hun LEE ; Dong Sik BANG ; Baik Kee CHO ; Won Koo LEE
Korean Journal of Dermatology 1990;28(2):222-226
A 53-year-old man developed some erythematous follicular macules accompanied with tingling sensation on both shoulders. Histologic finding showed a dense lymphocytic infiltrate around the infundibular portion of the follicle, where separation of the dermoepidermal junction was seen. The insect, obtained from the skin lesion, was identified as a larva of an Ap- hid
Aphids
;
Cryptococcosis*
;
Humans
;
Insect Bites and Stings
;
Insects
;
Larva
;
Middle Aged
;
Sensation
;
Shoulder
;
Skin
6.The Maturation of Circulating Primitive Erythroblasts in Human Embryos. A Karyometrical Study.
Young Sik JOO ; Won Bok LEE ; Dong Chang KIM
Korean Journal of Physical Anthropology 1990;3(2):119-129
The primitive erythroblasts in 21 cases of embryonic hearts from 4 to 9 weeks of gestation were studied with a light microscope. The nuclear diameter, the motosis, and the loss of nuclei of the primitive erythoblasts were analyzed quantitatively. The results obtained were as follows. 1. At 4 weeks of gestation, the blood cells consisted of proerythroblasts, along with basophilic polychromatophilic primitive erythroblasts. The nuclear diameter ranged from 3.20 µm to 9.20 µm, but the main range was from 4.20 µm to 6.00 µm. It was revealed that 9.50% had diameter of more than 6 µm. 2. At the fist half of the 7 week gestation when hepatic hemopoiesis developed, the blood cells consisted of basophilic, polychromatophilic, and eosinophilic erythroblasts. Cells of more than 6 µm in nuclear diameter were about 1.10% and thereafter gradually disappeared. The range of the nuclear diameters was from 2.60 µm to 7.00 µm, while a range from 3.40 µm to 5.20 µm wqs the main. The proportion of cells less than 4 µm in nuclear diameter was 39.58% and thereafter rapidly increased. 3. From the second half of 7 weeks to 9 weeks of gestation, the erythrocytes originating from hepatic hemopoiesis increasingly replaced the circulating primitive erythroblasts, which became mature during this time. The erythrocytes showed 72.88% at 9 weeks of gestation. The proportions of cells less than 4 µm in nuclear diameter in the first and second haIves of 8 weeks and 9 weeks were 52.73%, 80.02%, and 89.09%, which represented the rapid destruction of nuclei. 4. Mitosis in the primitive erythroblasts occurred principally up to the early 6th weeks, and very weakly at 8 weeks. 5. As the crown-rump length increased, the average nuclear diameter decreased very significantly (P<0.01, y=-0.2811X + 0.3171). The results suggest that distrilbution of the nuclear diameter, the maturity, the rate of nuclear loss, and the mitotic figure offer credible data for estimating embryonic age.
Basophils
;
Blood Cells
;
Crown-Rump Length
;
Embryonic Structures*
;
Eosinophils
;
Erythroblasts*
;
Erythrocytes
;
Heart
;
Humans*
;
Mitosis
;
Pregnancy
7.A Prospective Study of Comparison of Misoprostol and Dinoprostone for Cervical Ripening and Labor Induction.
Hyun Haing LEE ; Won Sik PARK ; Seung Joo SHIN
Korean Journal of Obstetrics and Gynecology 1999;42(11):2480-2485
OBJECTIVE: To compare the safety and efficacy of intravaginal misoprostol versus intracervical dinoprostone (prostaglandin E2 gel) for cervical ripening and labor induction. METHODS: 60 patients with indication for labor induction and unfavorable cervices were randomly assigned to receive either intravaginal misoprostol or intracervical dinoprostone. 50 microgram tablets of misoprostol were placed in the posterior vaginal fornix every 4 hours for a maximum of 3 doses or dinoprostone 0.5mg was placed into the endocervix every 6 hours for a maximum of 2doses. No more medication was given after either spontaneous rupture of membranes or beginning of active labor. RESULTS: Among 60 patients enrolled, 30 received misoprostol and 30 received dinoprostone. The average interval from start of induction to active labor was shorter in misoprostol group (6.5+/-3.2 hours) than in the dinoprostone group (10.7+/-7.3 hours) (p<0.05). Oxytocin augmentation of labor occurred more often in the dinoprostone group (36.7%) than in the misoprostol group (10.0%) (p<0.05). There was a higher prevalence of fetal distress (23.3% versus 3.3%) and tachysystole (16.6% versus 6.6%) in the misorprostol group than in the dinoprostone group(p<0.05). CONCLUSIONS: Vaginally administered misoprostol is an effective agent for cervical ripening and induction of labor. Furthermore, the cost of misoprostol ( 360/200microgram) is much less than that of dinoprostone ( 42,000/0.5mg). Cost benefits from administration of misoprostol are evident, especially in clinics under system of diagnosis-related group (DRG) : however when given at this dosage, it is associated with a higher prevalence of fetal distress and tachysystole than dinoprostone. Further studies to compare the safety of misoprostole to that of dinoprostone and to delineate an optimal dosing regimen for misoprostol are needed.
Cervical Ripening*
;
Cost-Benefit Analysis
;
Diagnosis-Related Groups
;
Dinoprostone*
;
Female
;
Fetal Distress
;
Humans
;
Membranes
;
Misoprostol*
;
Oxytocin
;
Pregnancy
;
Prevalence
;
Prospective Studies*
;
Rupture, Spontaneous
;
Tablets
8.Full-thickness skin grafts for vaginal reconstruction in mayer-fokitansky-hauser syndrom.
Jong Moon LEE ; Jae Sik HAN ; Won Kyun JUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(5):897-901
Mayer-Rokitansky-Kuster-Hauser Syndrom is characterized by the absence of the vagina and the uterus, the presence of apparently normal tubes and ovaries, feminine appearance, normal female secondary sexual characteristics, a normal 46, XX karyotypes, and a feminine psychosexual orientation. Absence of the vagina results from an embryological arrest in the development of the lower portion of the Mullerian system. Various methods of surgical treatment for the vaginal absence in this syndrom have been introduced but the ideal method to restore the original dimension and function of the normal vagina was not found. The two cases reviewed in this paper were all treated with modified McIndoe operation using full thickness skin grafts. Postoperatively both women were satisfied without complications, i,e. lack of skin graft, bleeding, urethrovaginal fistula, perforation of the rectum, rectovaginal fistula and significant vaginal stricture. This paper reveals the satisfactory results that were uniformly good.
Constriction, Pathologic
;
Female
;
Fistula
;
Hemorrhage
;
Humans
;
Karyotype
;
Ovary
;
Rectovaginal Fistula
;
Rectum
;
Skin*
;
Transplants*
;
Uterus
;
Vagina
9.Statistical Observations on the Vascular Changes in Hypertensives.
Book LEE ; Ki Weal KIM ; Won Sik YOUN
Journal of the Korean Ophthalmological Society 1959;2(1):38-44
No abstract available.
10.Synthesis of anti-HBs by cultured lymphocytes from uremic HBsAg carriers : effects of interferon.
Hi Bahl LEE ; Sung Won CHO ; Choon Sik PARK
Korean Journal of Nephrology 1993;12(4):533-541
No abstract available.
Hepatitis B Surface Antigens*
;
Interferons*
;
Lymphocytes*