1.A Case of Fournier's Gangrene.
Dong Lim KIM ; Jang Won SEO ; Seok Don PARK
Korean Journal of Dermatology 1990;28(5):602-605
No abstract available.
Fournier Gangrene*
2.A case of trichofolliculoma.
Jang Won SEO ; Myoung Ok KOH ; Seok Don PARK
Korean Journal of Dermatology 1991;29(5):685-687
No abstract available.
3.A Case of Dermoid Cyst Causing Deep Erosion of the Skull.
Seok Jong LEE ; Jae Won JANG ; Jung Ju LEE ; Do Won KIM ; Sang Lip CHUNG
Annals of Dermatology 2000;12(4):280-282
Dermoid cysts develop from sequestration of epithelium along lines of embryonic fusion.The most common locations are the lateral third of the eyebrows, nose, and scalp. These cysts are located in the subcutis; they are often adherent to periosteum, and may invade or erode underlying bane. A 34-year-old female presented with a solitary, skin colored, dome-shaped, child fistsized, subcutaneous mass on her right occiput. At operation, keratinous material was discharged and tufts of hair projected from opening of the cyst wall.The base of the cyst was firmly adherent to periosteum and diffuse depression with focal deep erosions of the outer table of skull was found.
Adult
;
Child
;
Cytochrome P-450 CYP1A1
;
Depression
;
Dermoid Cyst*
;
Epithelium
;
Eyebrows
;
Female
;
Hair
;
Humans
;
Nose
;
Periosteum
;
Scalp
;
Skin
;
Skull*
4.The Clinical Application of C-Reactive Protein in Acute Abdominal Pain.
Seok Joon JANG ; Jun Seok PARK ; Jae Wook KO ; Sang Won CHUNG ; Sung Pil CHUNG ; Tae Sik HWANG
Journal of the Korean Society of Emergency Medicine 2000;11(1):66-71
BACKGROUND: Abdominal pain is one of the most common complaints in the emergency department and the evaluation presents an extraordinary challenge to the emergency physician's skill. C-reactive protein, an acute phase protein which is increased in the presence of inflammation in various clinical conditions, has been proven useful in assessing disease severity, in monitoring the development of complications, and in evaluating the response to specific treatments. So we tried to determine whether CRP offers an advantage over other clinical or laboratory variables for decision-making in the management of acute abdominal pain in the emergency department. METHOD: Patients who came to a University Hospital ED with acute abdominal pain, between september 1, 1998 and November 30, 1998, were included in this study, Data collection included age, sex, duration of symptom, location of pain, and laboratory dta(white blood cell count, portion of neutrophils, ESR, CRP, amylase). RESULT: This study included 85 patients, 34 of whom were men. The mean age was 36.9+/-19.1 years. CRP might be useful to detect the serious condition, sensitivity 81%, but more useful to differentiate normal condition from serious condition in acute abdominal pain patients, specificity 83%. CONCLUSION: CRP is an useful indicator of decision-making to abdominal patients in the emergency department. Hospitalization or operation is very unlikely when CRP value is normal.
Abdominal Pain*
;
Acute-Phase Proteins
;
Blood Cell Count
;
C-Reactive Protein*
;
Data Collection
;
Emergencies
;
Emergency Service, Hospital
;
Hospitalization
;
Hospitals
;
Humans
;
Inflammation
;
Male
;
Neutrophils
;
Sensitivity and Specificity
5.Early Onset Generalized Pustular Psoriasis Accompanying IL36 Receptor Antagonist (IL36RN) Gene Mutation in a 14-year-old Korean Male Patient with No Family History.
Kyung Hea PARK ; Weon Ju LEE ; Seok Jong LEE ; Do Won KIM ; Yong Hyun JANG
Korean Journal of Dermatology 2014;52(2):151-153
No abstract available.
Adolescent*
;
Humans
;
Male*
;
Psoriasis*
7.A Case of Syphilis Probably Transmitted by Abnormal Imposition of Hands.
Hyo Chan JANG ; Young Mook YOON ; Dong Seok KIM ; Sang Won KIM
Korean Journal of Dermatology 1998;36(6):1143-1145
A 28-year-old man presented with a 6.0 * 5.0 cm sized ulcer on the anterior chest and widespread copper-red colored maculopapular eruptions. There was no past or family history of syphilis sign or STS. He had been taken imposition of hands twice to treat chronic hepatitis about 4 months prior to presentation. Thereby, the ulcerative lesion on the anterior chest developed as a result of erosive trauma through contact with infected fingernails. The clinical features and serologic tests as well as biopsy findings were consistent with syphilis. Spirochetes were observed under the dark field examination of the anterior chest lesion. On Warthin-Starry staining, spirochetes were identified in the epidermal area of the papular lesion. We report a case of unusual transmission of syphilis.
Adult
;
Biopsy
;
Hand*
;
Hepatitis, Chronic
;
Humans
;
Nails
;
Serologic Tests
;
Spirochaetales
;
Syphilis*
;
Thorax
;
Ulcer
8.Expression Pattern of bel-2 Protooncogene in Metastatic Prostate Cancer.
Seok Heun JANG ; Sung Won KWON
Korean Journal of Urology 1998;39(6):585-588
PURPOSE: Metastatic prostatic adenocarcinoma can be controlled by androgen ablation through the active process of programmed cell death in androgen responsive cells. However, about 20-30% of patients have no clinical response to androgen withdrawal. Because of the importance of apoptosis in effecting tumor control, factors involved in this process may be helpful in predicting androgen insensitivity. So, we evaluated the significance of bcl-2 protooncogene expression pattern with therapeutic response of prostatic cancer MATERIALS AND METHODS: We examined the cellular expression of bel-2 protein using immunohistochemical stain in tumor samples from 40 patients with metastatic prostatic cancer(stage D) and determined whether expression of blc-2 protein has related to the therapeutic response of prostatic cancer. RESULTS: The hormonal status of the patient's tumor was determined by the clinical response to therapy. Androgen independent cancer was defined as that subset of patients who experienced no initial response to androgen ablation, or who experienced disease relapse following an initial response to androgen ablation. So, we found that androgen dependent prostatic cancer was 22 patients and androgen independent prostatic cancer was 18 patients. The positive staining for bcl-2 was 27.3%(6/22) and 83.3%(15/18) in androgen dependent and independent prostatic cancer, respectively. It was significant difference(p<0.05). CONCLUSIONS: These results suggest that bcl-2 expression is associated with androgen independent prostatic cancer and used one of the factors to predict which patient with prostatic cancer will respond to androgen ablation.
Adenocarcinoma
;
Apoptosis
;
Cell Death
;
Humans
;
Prostate*
;
Prostatic Neoplasms*
;
Prostatic Neoplasms, Castration-Resistant
;
Recurrence
9.Effect of Extracorporeal Shock Wave on Ovary of Sprague-Dawley Rat.
Joong Hyun PARK ; Seok Heun JANG ; Sung Won KWON
Korean Journal of Urology 1996;37(9):955-958
Ovaries lie near the distal ureter where extracorporeal shock wave lithotripsy (ESWL) of calculi is performed. The question whether ESWL may induce morphological changes in ovary should be investigated in animal experiments. After applying shock waves to ovary of Sprague Dawley female rat, the histopathologic changes within the tissue of ovary were observed immediately after shock waves and after recovery. For animal subjects, 25 healthy rats weighing about 250 grams each were used. Five rats were designated as control, and remaining 20 received shock waves at 20 kV for 1,000 times using Pendulum-ESWL (Lithoring), a third generation lithotriptor. The 20 rats were divided into 4 groups before shock waves, and each group was sacrificed after 1, 7, 14, and 28 days, respectively, in order to compare the observed histopathologic changes. Edema, congestion and hemorrhage were observed in ovary after 1 and 7 days of shock waves, but the edema and congestion were significantly reduced on the 14th day and completely disappeared on the 28th day. There was no ovarian follicular changes or fibrosis on the whole. It is thought that the extracorporeal shock waves have no specific effects on the tissues of ovary, but further studies ate needed to determine its long term effects.
Animal Experimentation
;
Animals
;
Calculi
;
Edema
;
Estrogens, Conjugated (USP)
;
Female
;
Fibrosis
;
Hemorrhage
;
Humans
;
Lithotripsy
;
Ovary*
;
Rats*
;
Rats, Sprague-Dawley*
;
Shock*
;
Ureter
10.A Case of Renal Cell Carcinoma Metastatic to the Right Zygoma.
Hyo Chan JANG ; Byung Jun AHN ; Sang Won KIM ; Dong Seok KIM
Korean Journal of Dermatology 1999;37(4):556-558
Cutaneous metastasis from renal cell carcinoma is not unusual, occurring in 3 to 7%, although it may be overlooked. We report a case of metastatic renal cell carcinoma in a 74-year-old man who was presented with a 1.5 x 1.5 x 0.5 cm-sized nodule on the right zygoma for 3 months. A skin biopsy demonstrated the typical clear cell adenocarcinoma with PAS(+) granules in the cytoplasm and honeycombed or glandular configuration, compatible with metastatic renal cell carcinoma. Kidney ultrasonogram and abdomina1 CT scanning showed a large cystic mass on the upper pole of the left kidney. Furthermore radiologic studies revealed multiple metastatic lesions in the lung, liver and brain. He died 4 months later.
Adenocarcinoma, Clear Cell
;
Aged
;
Biopsy
;
Brain
;
Carcinoma, Renal Cell*
;
Cytoplasm
;
Humans
;
Kidney
;
Liver
;
Lung
;
Neoplasm Metastasis
;
Skin
;
Tomography, X-Ray Computed
;
Ultrasonography
;
Zygoma*