1.A Case of Battered Child Syndrome with Subdural hemorrhage.
Young Jun SONG ; Won Seop KIM ; Heon Seok HAN ; Soo Ahn CHAE
Journal of the Korean Child Neurology Society 1998;5(2):388-392
The diagnosis of a Battered Child Syndrome is made by the pediatrician, surgeon and the radiologist because almost parents deny the diagnosis or refuse to answer the doctor's questions. The imaging modalities play a key role in the investigation and documentation of the battered child syndrome, because of the high frequency of the typical skeletal lesion. Although physical abuse is denied by parents, the recognition of this entity is possible by the primary diagnostic imaging study in the suspected child abuse. The imaging studies are either a bone scan and x-ray series or a complete radiolographic skeletal survey by X-ray series. In an expected intracranial injury, a CT scan of the head is mandatory We experienced a case of Battered Child Syndrome in a 6 month-old male infant who had subdural hemorrhage and fractures of skull and ribs in different stages of healing and repair. The brief review of the literature was made.
Battered Child Syndrome*
;
Child
;
Child Abuse
;
Diagnosis
;
Diagnostic Imaging
;
Head
;
Hematoma, Subdural*
;
Humans
;
Infant
;
Male
;
Parents
;
Ribs
;
Skull
;
Tomography, X-Ray Computed
2.Eosinophilic Granuloma of the Lung.
Sang Ae YOON ; Won Bo JO ; Yang Seok CHAE ; Kap No LEE
Korean Journal of Pathology 1992;26(3):270-276
Eosinophilic granuloma of the lung, first described by Farrinaci et al. in 1951, is rare. A 35-year-old male smoker presented with recurrent pneumothorax. Open thoracotomy with bleb resection and biopsy was performed. Microscopically there was histological changes consistent with typical eosinophilic granuloma and intertitial fibrosis. The Langerhans cells showed positive reaction for S-100 protein and typical Birbeck granules in their cytoplasm. A brief summary of histopathological aspect of this disease and a review of literature are presented.
Male
;
Humans
;
Biopsy
3.Expression of bcl-2 Protein in Colorectal Adenoma and Adenocarcinoma and its Relationship with p53 and Apoptosis.
Ae Ree KIM ; Seong Jin CHO ; Nam Hee WON ; Yang Seok CHAE
Korean Journal of Pathology 1997;31(5):417-426
Either increased cellular proliferation or decreased death might result in an expansion of their numbers in the oncogenic process. Cellular apoptosis represents an autonomous suicide pathway that helps to restrict the cell number. However bcl-2 and mutant p53 inhibit programmed cell death. To determine whether the bcl-2 gene is activated during colorectal tumorigenesis and whether it has any relationship with p53 and apoptosis, we studied the expression of bcl-2 and p53 in the normal colonic mucosa, in the adenomatous polyps and in the adenocarcinomas using the immunohistochemical method. Also we evaluated the status of apoptosis using the in situ end labeling method. The bcl-2 immunoreactivity was restricted to the basal epithelial cells of all normal colonic mucosa and they were expressed in all adenomas and 86% of adenocarcinomas, especially in the superficial lesion of some tumors. Mutations of p53 were not found in the normal colonic mucosa, but they were present in dysplastic cells of adenomas (52%) and in cancer cells of the adenocarcinomas (47%). Apoptosis was confined to the tips of the normal colonic mucosa. It was more easily detected in the p53-positive adenomas than in the p53-negative adenomas (p=0.010). In the adenocarcinomas, the findings of apoptotic process are not related with p53 mutation (p=0.3) and bcl-2 expression (p=0.187). p53 and bcl-2 are probably one step of several apoptotic processes in the adenocarcinomas.
Adenocarcinoma*
;
Adenoma*
;
Adenomatous Polyps
;
Apoptosis*
;
Carcinogenesis
;
Cell Count
;
Cell Death
;
Cell Proliferation
;
Colon
;
Epithelial Cells
;
Genes, bcl-2
;
Mucous Membrane
;
Suicide
4.A Case of Fibroadenoma Arising in Accessory Axillary Breast Tissue.
Tae Hyung KIM ; Sang Won KIM ; Dong Seok KIM ; You Ho CHAE
Korean Journal of Dermatology 1994;32(3):483-487
A 25-year-old woman had a 2-month history of a 1.7 x 1.4cm sized lirm nodule, which was deeply located in 5.0 x 4.0cm sized soft fatty tissue on the right axilla. There was no history of axillary swelling with the symptoms or signs related to her menstrual periods. She underwent an excisional biopsy of the firm nodule and a simple biopsy of the soft tissue. The histopathologic findinga associated with both lesions revealed the usual feat Ures of fibroadenoma with accessory breast tissue. There was no occurrence or relapse of any other lasions during the careful one-year follow-up after excision of the firm nodule. This is an unusual case in a review of Korea literatures.
Adipose Tissue
;
Adult
;
Axilla
;
Biopsy
;
Breast*
;
Dapsone
;
Female
;
Fibroadenoma*
;
Follow-Up Studies
;
Humans
;
Korea
;
Recurrence
5.Transmyocardial Laser Revascularzation for Patients with Recurrent Angina after CABG: Report of 3 cases.
Ho Seok LEE ; Kay Hyun PARK ; Tae Gook JUN ; Pyo Won PARK ; Hurn CHAE
The Korean Journal of Thoracic and Cardiovascular Surgery 2000;33(7):576-580
Transmycardial laser revascularization has made its position as a sole therapy for patients with chronic angina nonamenable to maximal medical therapy, percutaneous transluminal coronary angioplasty, and coronary artery bypass grafting. We report three cases of transmyocardial laser revascularization as a sole therapy for patients with recurrent angina after CABG.
Angioplasty, Balloon, Coronary
;
Coronary Artery Bypass
;
Humans
;
Transmyocardial Laser Revascularization
6.Abrasion of abutment screw coated with TiN.
Seok Won JUNG ; Mee Kyoung SON ; Chae Heon CHUNG ; Hee Jung KIM
The Journal of Advanced Prosthodontics 2009;1(2):102-106
STATEMENT OF PROBLEM: Screw loosening has been a common complication and still reported frequently. PURPOSE: The purpose of this study was to evaluate abrasion of the implant fixture and TiN coated abutment screw after repeated delivery and removal with universal measuring microscope. MATERIAL AND METHODS: Implant systems used for this study were Osstem and 3i. Seven pairs of implant fixtures, abutments and abutment screws for each system were selected and all the fixtures were perpendicularly mounted in liquid unsaturated polyesther with dental surveyor. After 20 times of repeated closing and opening test, the evaluation for the change of inner surface of implant and TiN-coated abutment screw, and weight loss were measured. Mann-Whitney test with SPSS statistical software for Window was applied to analyze the measurement of weight loss. RESULTS: TiN-coated abutment screws of Osstem and 3i showed lesser loss of weight than non-coated those of Osstem and 3i (P < .05, Mann-Whitney test). CONCLUSION: Conclusively, TiN coating of abutment screw showed better resistance to abrasion than titanium abutment screw. It was concluded that TiN coating of abutment screw would reduce the loss of preload with good abrasion resistance and low coefficient of friction, and help to maintain screw joint stability.
Collodion
;
Friction
;
Joints
;
Tin
;
Titanium
;
Weight Loss
7.Plexiform Schwannoma.
Kyo Beom LEE ; Yang Seok CHAE ; Nam Hee WON ; Seung Yong PAIK
Korean Journal of Pathology 1988;22(1):105-109
Three case of plexiform schwannoma displayed multinodular masses and microscopically a multicentric pattern of growth featuring Antoni A cellular component, Verocay bodies and presence of Antoni B areas. Clinically von Recklinghausen's disease was not observed in all cases. The first patient was a 17 year old male who had a protruding nodule of walnut size which was located at the dermis of the left flank for 13 years. The second case, a 25 year old male, had an irregular whitish brown multinodular mass in the choana for 5 years. The last case, a 56 year old woman, had an ovoid yellowish brown mass with multiple nodules in the retroperitoneum.
Female
;
Male
;
Humans
8.Determination of Reduced Glutathione in Red Blood Cells.
Eun Ah CHANG ; Sung Won KIM ; Seok Lae CHAE ; Young Joo CHA
Korean Journal of Clinical Pathology 1997;17(2):238-244
BACKGROUND: The product of oxygen-free radicals inf1ict oxidative injuries on healthy cells. Antioxidants such as superoxide dismutase(SOD), glutathione peroxidase, and reduced glutathione(GSH) are present in almost all cells and play important roles in metabolism, transport, and cellular protection. We measured blood GSH levels in healthy controls and patients with non insulin dependent diabetes mellitus(NIDDM) for evaluation of the clinical usefulness of GSH. METHODS: Erythrocyte GSH levels were measured in fifty healthy controls and thirty NIDDM patients with diabetic retinopathies by Beutler's method. We also tested within-run precision, between-run precision, linearity and recovery rate to evaluate this method measuring erythrocyte GSH levels. RESULTS: The GSH levels (mean +/-SD) of NIDDM patients (5.03+/-0.67mumo1/Hb) were significantly lower than those of healthy control group (6.46+/-0.85mumo1/Hb)(P<0.001). The results of within-run precision and between-run precision when stored at 4degrees Cwere excellent (coefficient of variation were 2.79% and 2.42%, respectively), however, when stored at the room temperature the GSH levels were sharply declined. The linearity and recovery rate were acceptable. CONCLUSIONS: The prescision, linearity, and recovery rate of GSH measurement were excellent. The GSH levels in NIDDM patient group were reduced, and this probably contributes to the defective defense mechanism against increased oxidative stress. Additional measurement of other antioxidants such as superoxide dismutase and glutathione Peroxidase may be required to clarify the pathologic significance of glutathione metabolism in various diseases.
Antioxidants
;
Diabetes Mellitus, Type 2
;
Diabetic Retinopathy
;
Erythrocytes*
;
Glutathione Peroxidase
;
Glutathione*
;
Humans
;
Insulin
;
Metabolism
;
Oxidative Stress
;
Superoxide Dismutase
;
Superoxides
9.A clinical study of treatment of displaced fractures of femur neck with internal fixation in elderly patients.
Jay Suk CHANG ; Won Yong SHON ; Hong Chul SHIN ; Dong Ju CHAE ; Seok Hyun LEE
The Journal of the Korean Orthopaedic Association 1992;27(1):131-138
No abstract available.
Aged*
;
Femur Neck*
;
Femur*
;
Humans
10.An analysis of immunoglobulins and the role of allergy in otitis media with effusion.
Yong Seong SHIN ; Woo Seok CHAE ; Chul Won PARK ; Kyung Sung AHN ; Sun Kon KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(2):207-212
No abstract available.
Hypersensitivity*
;
Immunoglobulins*
;
Otitis Media with Effusion*
;
Otitis Media*
;
Otitis*