1.Ultrasonic Study of Lumbar Spinal Canal in Patient with Lumbago or Sciatic Pain
Kyung Goo YOON ; Sang Won PARK
The Journal of the Korean Orthopaedic Association 1983;18(6):1055-1061
No abstract available in English.
Humans
;
Low Back Pain
;
Spinal Canal
;
Ultrasonics
3.Effect of External Factors on Diastase Activity in Water.
Bock Sang YOON ; Ho Sup HYUN ; Nam Won PAEK
Korean Journal of Preventive Medicine 1974;7(1):107-113
Many factors exert an influence on enzyme activity and thus on the rate of reactions that they catalyse. The most important of these factors are pH, temperature, substrate concentration, and the concentration of some inhibitors present. A solution of the enzyme diastase, which breaks down molecules of the polysaccharide starch to the disaccharide maltose by hydrolysis, was provided. Activity of these enzyme was measured by the rate at which starch was removed from the reaction mixture. These experiments were designed to study this reaction rate under varying conditions and the following results were obtained. 1. The range of optimum pH for this enzyme at room temperature was 4.0-7.0 and the optimum pH was 5.0. 2. The range of optimum temperatures for this enzyme at pH 7.0 was 30-50 degrees C and the optimum temperature was 40 degrees C. 3. The relationship between the enzyme activity and substrate concentration could be expressed by the Michaelis-Menten equation. The limiting velocity of these enzyme at room temperature and pH 7.0 was 415 microgram starch removed/ml of reaction mixture/min and Km, Michaelis constant, was 343 microgram/ml. 4. Inhibitors NaCl and HgCl2 blocked this enzyme activity completely at 1% and 0.01% respectively.
Amylases*
;
Hydrogen-Ion Concentration
;
Hydrolysis
;
Maltose
;
Mercuric Chloride
;
Starch
;
Water*
4.A Clinical Study of Femoral Neck Fracture
Sang Won PARK ; Hak Yoon KIM ; Hong Kun LEE
The Journal of the Korean Orthopaedic Association 1989;24(4):1025-1034
We analysed forty-six cases of femoral neck fracture treated with internal fixation and followed for more than one year at Korea University Hospital from January 1979 to June 1986 and the following results were obtained. 1. Sex distribution was 23 cases(50%) male and 23 cases(50%) female, and average age was sixty years old (range from 21 to 91 years). 2. The most common cause of injury was slip down(76%). 3. The most common type of fracture was Garden's type III(46%) and Pauwels' type III (67%). 4. In cases of internal fixation, the most commonly used method was closed reduction and multiple pinning under the local aneshtesia(83%). 5. Bony union was established within 5.9 months in average. 6. Among forty six cases, 7 cases(15%) of avascular necrosis, 4 cases(9%) of malunion, and 2 cases(4%) of nonunion was occurred. 7. The clinical results were excellent in twenty cases(43%), good in sixteen cases(35%), fair in seven cases(15%), and poor in three cases(7%) according to Lunceford's assessment.
Clinical Study
;
Female
;
Femoral Neck Fractures
;
Femur Neck
;
Humans
;
Korea
;
Male
;
Methods
;
Necrosis
;
Sex Distribution
5.Distraction-motion Arthroplasty for the Management of Kienböck's Disease
Moon Sang CHUNG ; Choong Hee WON ; Byung Hwa YOON
The Journal of the Korean Orthopaedic Association 1987;22(1):92-96
Many kinds of operations have been devised to treat Kienböck's disease with variable results. But no one have mentioned about the advantage of early motion in distraction to prevent the fibro-osseous ankylosis and carpal collapse. Two cases with Kienböck's disease were treated by the complete excision of the lunate and replacement of it with pronator quadratus muscle pedicled rectangular bone graft. Once these procedures were accomplished, the distraction-motion devices were used to maintain the joint surfaces separated at predetermined distances while kinematically normal joint motion was gradually restored. Although the experience is limited to two cases, the final results seem to be very promising.
Ankylosis
;
Arthroplasty
;
Joints
;
Transplants
6.Prefabricated Muscle Flap for Difficult wound Around the Knee Joint.
Hoon Bum LEE ; Pil Dong CHO ; Sug Won KIM ; Sang Yoon KANG ; Yoon Kyu CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(5):917-922
The reconstruction of soft tissue defects with open fracture around the knee joint is limited by its unique location. Free tissue transfer is hindered by the selection of the recipient vessel and problems of microsurgery. The arc of rotation, defect size, and location must be taken into consideration in the use of regional muscle transfer such as gastrocnemius. According to Mathes et al, the flap survival can be enhanced by selective division of the dominant segmental pedicles, only a part of which can normally be transposed safely on its minor segmental pedicle. Neovascularization, vascular proliferation, and dilatation have also been produced by the delay procedure using silicone sheets. The authors have used the delay procedures with wrapping of the gracilis or sartorius muscle which enabled distally-based transposition of these muscles. The method showed satisfactory outcome in resurfacing the wound around the knee joint. The indictions for this procedure were defects of moderate size and those difficult to reach with conventional muscle flaps. The flap could reach the upper one-third of the lower leg. Other merits are relative simplicity and reliability without significant extension of hospital stay. The drawbacks are the two operative procedures necessary and the risk of infection due to silicone sheets.
Dilatation
;
Fractures, Open
;
Knee Joint*
;
Knee*
;
Leg
;
Length of Stay
;
Microsurgery
;
Muscles
;
Silicones
;
Surgical Procedures, Operative
;
Wounds and Injuries*
7.Collision carcinoma in a metastatic neck node.
Sun Hee LEE ; Kwang Yoon JUNG ; Jong Ouck CHOI ; Sang Ae YOON ; Nam Hee WON
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(3):410-413
No abstract available.
Neck*
8.Repair of anterior skull base defect using pericranial-septal flap after craniofacial resection.
Chul Ho JANG ; Ie Dong KIM ; Won Ki WANG ; Sang Won YOON
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):734-739
No abstract available.
Skull Base*
;
Skull*
9.Application of Gait Analysis to the Patients with Cervical Myelopathy.
Sang Won YOON ; Seung Chul RHIM ; Sung Woo ROH ; Jong Youn YU ; Sang Bae HA
Journal of Korean Neurosurgical Society 2000;29(4):528-535
No abstract available.
Gait*
;
Humans
;
Spinal Cord Diseases*
10.The Significance of E-cadherin Expression in Transitional Cell Carcinomas of the Bladder.
Sang Won JUNG ; Sang Yoon KIM ; Hong Sup KIM
Korean Journal of Urology 1999;40(9):1125-1131
PURPOSE: To investigate the significance of E-cadherin expression in transitional cell carcinoma of bladder, as the prognostic value. MATERIALS AND METHODS: We have analyzed its immunoreactivity in 41 transitional cell carcinomas using a labelled streptavidin-biotin immunoperoxidase technique on the formalin-fixed and the paraffin-embedded tissues. E-cadherin is a Ca2+-dependent intracellular adhesion molecule of the epithelial tissue and the urothelium. We determined the E-cadherin expression in bladder carcinoma using immunohistochemical method and investigated relationship between pathological and clinical data. RESULTS: The percentage of cases showing weak pattern was higher in cases with high-grade or high-stage tumors as compared with those of low grade or low stage. The E-cadherin was expressed in a normal membranous pattern in all control cases. Abnormal E-cadherin expression was found in 8 of 20 superficial tumors and in 19 of 21 invasive tumors. Abnormal immunoreactivity was related to tumor differentiation and stage. Eight of 13 well-differentiated tumors showed preservation of membranous E-cadherin immunoreactivity, while 2 of 28 moderately and poorly differentiated tumors demonstrated normal staining patterns. CONCLUSIONS: We conclude that the loss of expression of E-cadherin in high grade or high stage transitional cell carcinoma of bladder is associated with bladder wall invasion, indicates metastasis, and may be clinical value in the assessment of prognosis.
Cadherins*
;
Carcinoma, Transitional Cell*
;
Immunoenzyme Techniques
;
Neoplasm Metastasis
;
Prognosis
;
Urinary Bladder*
;
Urothelium