1.A Study on the Typhoid Granuloma in the Bone Marrow Biopsy of Patients with Typhoid Fever.
So Young JIN ; Kyung Won LEE ; Tai Seung KIM
Korean Journal of Pathology 1986;20(4):462-469
To evaluate the appearance rate of typhoid granuloma, a clinical and histological study was made on bone marrow smears or biopsies of 60 patients with proven typhoid fever. The results were as follws: 1) Sixty cases consisted of 34 cases of bacteriologically proved group, 10 cases of serologically proved group, and 16 cases of clinically suspected group. The positive culture rate from bone marrow fluid was the highest (70.6%) among specimens although it was obtained 1.6 days in average after the administration of antibiotics. 2) Fourth-eight cases by bone marrow smear revealed the M:E ratio of 3.93:1 in average, mild myeloid hyperplasia and 50.5% of appearance rate of typhoid cells. 3) Fourth-nine cases of bone marrow biopsy revealed 8 cases of typhoid granuloma, all of which belonged to the bacteriologically proved group. All these have no pathognomonic morphologic features. 4) Fourty cases of bone marrow examination of patients with FUO except typhoid fever revealed no typhoid cells in smear and 3 cases of granulomatous lesion from two patients with miliary tuberculosis and one patient with Hodgkin's lymphoma.
Biopsy
2.Clinical Characteristics and Use of Psychotropic Agents among HIV-Infected/AIDS Patients Referred for Psychiatric Consultation.
Sang Ho SHIN ; Hyun Chung KIM ; So Young YOO ; Hyoung Shik SHIN ; Sung Doo WON ; So Hee LEE
Korean Journal of Psychosomatic Medicine 2014;22(1):31-39
OBJECTIVES: This study aimed to investigate the psychiatric status of HIV-infected/AIDS inpatients in a general hospital over the past 2.5 years. METHODS: A retrospective chart review was conducted of psychiatric consultations performed between January 1, 2011, and July 30, 2013. The records of 97 HIV-infected/AIDS patients were analyzed. These included a total of 282 psychiatric consultations. RESULTS: Of the 97 patients, 91(93.8%) were male, the mean age was 48 years, and mean number of consultations was 2.8. Depressed mood was reported in 102 consultations(23.8%), insomnia in 60(14.0%), and anxiety in 31(7.2%). Psychiatric disorders diagnosed on initial consultation included depressive disorder(37 patients ; 37.0%), cognitive disorder(11 ; 11.0%), and delirium(9 ; 9.0%). Recommended psychotropic medication included Lorazepam(99 ; 17.2%), Escitalopram(90 ; 15.7%), and Quetiapine(84 ; 14.6%). CONCLUSIONS: The main complaints of HIV-infected/AIDS patients were depressed mood, insomnia, and suicidal ideation(including suicide attempts). In total, 85(93.3%) patients of those consulted were diagnosed as meeting the criteria for a psychiatric condition. However, considering that only 16.9% of patients consulted received follow-up treatment, longitudinal research is needed to examine the influence of psychiatric disorders on the transmission of HIV-infection/AIDS, as well as on prognosis and treatment adherence.
Anxiety
;
Follow-Up Studies
;
HIV
;
Hospitals, General
;
Humans
;
Inpatients
;
Male
;
Prognosis
;
Referral and Consultation
;
Retrospective Studies
;
Sleep Initiation and Maintenance Disorders
;
Suicide
3.Comparison of Benign and Malignant Microcalcifications.
Hae Jung PARK ; So Hee HAHM ; Jae Won AHN ; Ye Ri LEE ; Oak KIM
Journal of the Korean Radiological Society 1995;33(3):471-475
PURPOSE: To evaluate morphologic characteristics of the microcalcifications on mammography that were confirmed pathologically. MATERIALS AND METHODS: Forty five cases of microcalcifications on mammography (fifteen cases of benign lesion, thirty cases of maiignancy) were retrospectively reviewed. RESULTS: The number of microcalcifications within 1 cm2 were more than 5 in 22 cases (73%) of 30 malignancy and less than 5 in 11 cases (73%) of 15 benignity. The heterogeneity of microcalcifications were seen in 26 cases of malignancy (87%) and the homogeneity of microcaicifications were 11 cases of benignity (73%). The morphologic characteristics of the microcalcifications were linear-V shape in 9 cases (30%), punctate shape in 8 cases (27%), fine stippled shape in 7 cases (23%), and round dot shape in 6 cases (20%) of malignancy and, round dot shape in 11 cases (73%), punctate shape in 2 cases (13%), and linear-V shape in 2 cases (13%) of benignity. CONCLUSION: Numerous irregular microcalcifications that are heterogenous in size and morphology were strong indicators of malignancy.
Mammography
;
Population Characteristics
;
Retrospective Studies
4.Clinical Analysis of congenital anomalies in the newborn infant.
Young Sub KIM ; Yang Sook CHOI ; Chan Yung KIM ; Hae Young KIM ; So Won AHN
Journal of the Korean Pediatric Society 1985;28(2):131-139
No abstract available.
Humans
;
Infant, Newborn*
5.Fatal staphylococcal endocarditis complicated with systemic septic emboli.
Joong Won KIM ; Sun Ho CHANG ; Jun Hee WOO ; So Yong JIN ; Dong Hwa LEE
Korean Journal of Infectious Diseases 1992;24(1):55-63
No abstract available.
Endocarditis*
6.MASTOPEXY AND REDUCTION MAMMOPLASTY THROUGH THE PERIAREOLAR INCISION.
Bae Won BAE ; So Ra KANG ; Heung Sik PARK ; Chin Ho YOON ; Han Joong KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):1145-1152
No abstract available.
Female
;
Mammaplasty*
7.The Study on 182 Cases of Exchange Transfusion.
Gie Hwa YOON ; Ock Seung JEONG ; So Won AHN ; Yung Seok JEON
Journal of the Korean Pediatric Society 1982;25(12):1243-1251
No abstract available.
8.Plasminogen Activator Inhibitor-1, c-erbB2, and p53 Protein Overexpression and Prognosis in Gastric Adenocarcinoma.
Ayoung PARK ; So Young JIN ; Dong Won KIM ; Dong Wha LEE
Korean Journal of Pathology 2000;34(8):559-566
Despite its fall in incidence, gastric adenocarcinoma remains a common disease with dismal prognosis worldwide. A better understanding of its tumorigenesis and biologic properties of tumor cells related to invasion and metastasis is crucial to improving diagnosis and treatment. Conflicting results concerning the relationships between overexpression of PAI-1, c-erbB2, and p53 protein and biologic behavior of gastric carcinoma have been noted. The aim of this study was to evaluate the value of overexpression of PAI-1, c-erbB2, and p53 protein as prognostic factors in gastric adenocarcinoma. Overexpression of PAI-1, c-erbB2, and p53 protein by immunohistochemistry was correlated with variable clinicopathological parameters and patients' survival in 80 cases of gastric adenocarcinoma. Overall PAI-1 expression rate was 63.7% (51/80) and higher in advanced cancer (p=0.0003) and nodal metastasis (p=0.003) groups. Overall c-erbB2 expression rate was 43.8% (35/80) and higher in antral (p=0.03), differentiated (p=0.001), intestinal (p=0.0007), and expanding (0.03) groups. The p53 protein overexpression was 37.5% (30/80) and higher in early cancer (p=0.02), differentiated (p=0.006) and intestinal groups (p=0.009). Patients with PAI-1, c-erbB2, and p53 protein positive tumors tended to have poorer survival rates than patients with PAI-1, c-erbB2, and p53 protein negative tumors, but the difference was not statistically significant (p=0.25, 0.37, 0.52). Our data indicated that PAI-1 overexpression is one of the poor prognostic factors in gastric adenocarcinoma and c-erbB2 and p53 protein seem to be involved in the early stage of carcinogenesis of intestinal type-gastric adenocarcinoma.
Adenocarcinoma*
;
Carcinogenesis
;
Diagnosis
;
Humans
;
Immunohistochemistry
;
Incidence
;
Neoplasm Metastasis
;
Plasminogen Activator Inhibitor 1
;
Plasminogen Activators*
;
Plasminogen*
;
Prognosis*
;
Staphylococcal Protein A
;
Stomach Neoplasms
;
Survival Rate
9.A study on the T lymphocyte subsets, plasma neopterin and serum lgE in patients with atopic dermatitis.
Seon Kyo SUH ; Moon kyu KIM ; So Won KIM ; Jae Bok JUN ; Sang Lip CHUNG
Korean Journal of Dermatology 1993;31(6):877-883
BACKGROUND: Many physiologic, pharmacologic and immunologic abnormalities were reported in atopic dermatitis but the cause and pathogenesis of the disease remain obscure. OBJECTIVE: This study was done to investigate the systemic immunologic abnormalities in atopic dermatitis. METHOD: To evaluate the cell mediated immunity, me quantified pei ipheral blood T lymphocytes and their subsets, using flow cytometery, and assessed plasma neopteiin levels by means of radioimmunoassay. To evaluate the abnormal humoral immunity, we assessed the serum IgE levels by means of enzyme-immunoassay. RESULTS: Mean proportions of peripheral blood T lymphocytes and, heir subsets in atopic Dermatitis patients were within normal limits. Hut the suppvessor/cytotoxic T lyrphocytes(T8) were significantly decreased in the group of se"ere atopic dermatitis compared with the group of mild atopic dermatitis(P<0.05). Plasma neopterin lervels in the group of atopic dermatitis were found to be significantly elevated as compared vith the control group(P<0.01), but no significant cifference was found between the mild and severe group of atcpic dermatitis(P>0.05). Mean serum IgE levels in the patients with atopic dermatitis were higher than reference value. But there was no significant difference between the mild and severe atopic dermatitis group. Serum IgE levels ivere negatiiely correlated with T8(r=-0.3774, P<0.05) and positively with T4/T8 ratio(r =0.5007, P<0.05). Conclusions : These data;uggest that the atopic der matitis has abr ormalities in cell mediated immunity as well as elevated IgE level.
Dermatitis, Atopic*
;
Humans
;
Immunity, Cellular
;
Immunity, Humoral
;
Immunoglobulin E
;
Neopterin*
;
Plasma*
;
Radioimmunoassay
;
Reference Values
;
T-Lymphocyte Subsets*
;
T-Lymphocytes
10.A Case of Collecting Duct Carcinoma of Kidney.
Joong Won WOO ; So Jin YOU ; Chang Kyu LEE ; Hyun Yul RHEW
Korean Journal of Urology 1997;38(5):551-554
Most renal carcinomas are thought to originate from the epithelial cells of proximal convoluted tubules in the renal cortex. Collecting duct carcinoma is a recently recognized histological variety of renal cell carcinoma considered to arise from the epithelium of the collecting ducts. It is important to distinguish the collecting duct carcinoma from ordinary renal cell carcinoma, because which has an aggressive clinical course with early metastasis and death. But in patients, the natural course of the disease and its response to treatment have not been clearly established. Herein we report a case of collecting duct carcinoma of kidney in 38-year-old woman who had generalized edema and left flank dull pain. The preoperative diagnosis was left renal cell carcinoma on physical examination and radiologic finding, and left radical nephrectomy was done.
Adult
;
Carcinoma, Renal Cell*
;
Diagnosis
;
Edema
;
Epithelial Cells
;
Epithelium
;
Female
;
Humans
;
Kidney*
;
Neoplasm Metastasis
;
Nephrectomy
;
Physical Examination