BACKGROUND: Aphasia is common in stroke patients. However, studies about characteristics and prog- nosis of aphasia by acute ischemic stroke were insufficient. The aim of this study is to disclose vascular lesions causing aphasia symptom and to evaluate and clarify types, severity and recovery patterns of vascular aphasia using quantitative aphasia test. METHODS: Twenty six patients were included in this study, who had aphasia symptoms due to acute ischemic lesions confirmed by MRI or CT. Standardized test of Korean version-the Western Aphasia Battery (K-WAB) was performed in all subjects in acute stagte of stroke and was repeated 3 month later. Based on neuroimaging findings and results of aphasia tests, we divided all subjects into two groups, cortical aphasia and subcortical aphasia, and classified further into 8 types. The severity of aphasia measured by aphasia quotient (AQ) was graded. Changes in aphasia types and AQ and prognosis between cortical and subcortical aphasia was analyzed. RESULTS: Various vascular lesions caused aphasia symptoms in cortical and subcortical areas with good clinico-anatomical correlations. Eighteen patients(69.2%) had cortical aphasia and 8(30.8%) had subcor- tical one. Among 8 types of aphasia, 7 types were detected in our patients, and the most frequent type is global aphasia(30.8%). The mean incremental score of AQ between initial and follow-up test was 21.1+/-14.0. The distribution of severity of aphasia was as follows; grade I, 3.8%; grade II, 19.2%; grade III, 42.3%; and grade IV, 34.6%. Twenty one patients(80.8%) were followed up 97.9+/-7.4 days after initial test. Subjects who showed improvement in aphasia were 13(61.9%). Nine out of 13 belonged to cortical aphasia group and 4 out of them belonged to subcortical aphasia group. There was no significant difference in prognosis between cortical and subcortical aphasia group(p=0.58). CONCLUSION: Our study discloses various acute vascular lesions cause aphasia. It also provides cha- racteristics of patients with aphasia by acute ischemic stroke, such as types, severities and recovery patterns, which may help to assess vascular aphasia and its prognosis.
Aphasia* ; Follow-Up Studies ; Humans ; Magnetic Resonance Imaging ; Neuroimaging ; Neuropsychological Tests* ; Prognosis ; Stroke*

No abstract available.
Alcoholics* ; Humans ; Skin*

Todays, remnant split-thickness skin graft is stored for graft failure or for delayed grafting. Refrigerated skin is usually stored for 3 weeks, after which, cellular respiration ceaces. Even though the refrigerated skin can be used before 3 weeks after harvest, the success rate of the skin graft is usually lower than in case of fresh skin. One of the most reliable explanations is multiplication of microorganisms on the stored skin, that is, the more microorganisms on the refrigerated skin, the less the success rate of grafts. For this reasons, some kind of antibiotics have been used for storage of the split-thickness skin piece. But there is no report about the effect of antibiotics on stored skin. We want to know the effect of the antibiotics on stored skin. For this purpose, we did three experiments for qualititative bacteriology of refrigerated skin. Experiment 1 was qualititative identification of microorganisms colonizing split-thickness skin after 2 weeks storage in low temperature, and sensitivity tests for identified microorganisms. On the basis of experiment 1, the proper antibiotics were selected and samples of split-thickness skin were stored using this antibiotics. At 2 weeks after storage in low temperature, samples of split-thickness skin were cultured for identification of bacterial growth. This is experiment 2. Experiment 3 is histologic examination of the split-thickness skin involved in experiment 1 and 2.In the experiment 1, we found five kinds of microorganisms in 9 out of 30 split-thickness skin samples. The most common microorganism was coagulase negative Staphylococcus which was found in 4 samples. Through the antibiotics sensitivity test, teicoplanin was selected as the most proper antibiotics. In experiment 2, we could not find any microorganisms in 30 split-thickness skin samples. In experiment 3, there were no histologic differences in the split-thickness skin samples whether antibiotics were used or not. Through these results, we have confirms that split-thickness skin pieces are more safely stored using proper antibiotics.
Anti-Bacterial Agents* ; Bacteriology ; Cell Respiration ; Coagulase ; Colon ; Skin* ; Staphylococcus ; Teicoplanin ; Transplants

No abstract available.
Animals ; Rats* ; Transplants* ; Veins*

No abstract available.
Arthroplasty, Replacement, Hip* ; Prostheses and Implants*

The authors analyzed clinical and radiographic results of the 87 cases which had done THRA with porous coated femoral stem followed up more than 2 years to study the difference of clinical and radiologic findings between the absence (group 1 ; 53 cases) and presence(group 2 ; 34 cases) of the porous coating in superolateral portion of the femoral stem. The following results were obtained : 1. Harris hip scores were improved 34.4 points from 56.5 points preoperatively to 90.9 points postoperatively in group Ι, and 32.7 points from 61 points preoperatively to 93.7 points postoperatively in group 2. The clinical results of the group 1 were Excellent in 45 cases, Good in 5 cases and Fair in 3 cases, and clinical result of the group 2 were Excellent in 33 cases and Good in 1 case. 2. The changes of femoral stem angle were below 2 degrees in 7 cases, above 2 degrees in 2 cases in group 1, and below 2 degrees in 5 cases, but not found more than 2 degrees of change of the femoral stem angle in group 2. 3. The osteolysis around femoral stem were 15 cases(28%) in Group 1, and 5 cases(15%) in Group 2. Diffuse osteolysis were 3 cases in Group 1, but was not observed in Group 2. 4. The vertical subsidence more than 2 mm was 3 cases in group 1, but was not observed in group 2. 5. The stable femoral stem were 51 cases in group 1, and 34 cases in group 2. The unstable femoral stem were 3 cases in group 1, but was not observed in group 2. Above results suggest that the porous coating in the superolateral portion of the femoral stem showed better results in radiologic and clinical findings in short term follow up.
Clinical Study ; Follow-Up Studies ; Hip ; Osteolysis

No abstract available in English.
Humans ; Low Back Pain ; Spinal Canal ; Ultrasonics

No abstract available.

The occurrence of a lipoma-like condition associated with trauma would tend to be regarded as a subset of or a separate entity from ordinary lipoma. We report herein a case of traumatic Lpoma occuring on the dorsum of the left hand. The patient was a 46-year-old male, who had struck his left hand against a window about two months previously and noted casually an asymptomatic, firm, dermal lesion at the site of injury. On gross examination, the enucleated nodule was a smooth-surfaced, yellow fatty mass measuring 0.3 × 0.5 × 0.3cm which looked like a kernel of corn. Microscopic examination revealed encapsulated mature fat consistent with lipoma.
Hand ; Humans ; Lipoma* ; Male ; Middle Aged ; Zea mays

We studied the natural history of asymptomatic early avascular necrosis of the femoral head in forty-three patients(forty-three hips) who had been treated with arthroplasty due to progressed avascular necrosis of femoral head but had no symptoms in the other side. All initial lesions were classified with Ficat staging and International classification(ARCO). The duration until symptom onset and radiologic evidence of disease progression were evaluated. The average follow up period was over 37 months. Among forty-three hips, twenty-nine cases(67.4%) remained asymptomatic until last follow up but fourteen cases(32.6%) were symptomatic during the follow up, and twenty-six cases(60.5%) did not progress on the radiography but seventeen cases(39.5%) progressed to Ficat stage 3 or 4. Fifteen cases of IA, IIA, IB-cental and II B-central without lateral lesion did not occur symptom and didnt progress to Ficat stage 3 or 4 over a period of average 47 months(24-71 months). But fourteen cases of IB, IC, g B and II C progressed to Ficat stage 3 or 4 and they were all lateral lesion. These results suggest careful observation only can be done in the case of small involvement(less than 15%) and medial or central lesion relatively over a long period of time but for the large involvement(more than 30%) and especially lateral lesion, aggressive surgical treatment may be considered even though the early stage of disease for the prevention of progression. However it will need more period of time to accurately compare the results of various methods of treatment.
Arthroplasty ; Disease Progression ; Follow-Up Studies ; Head* ; Hip ; Natural History* ; Necrosis* ; Radiography