1.Ultrastructural changes in endothelium by in-situ perfusion of hyperosmolar mannitol solution into rat brain.
Soon Kil ERM ; Kyung Yong KIM ; Won Bok LEE ; Dong Chang KIM
Korean Journal of Anatomy 1993;26(4):416-427
No abstract available.
Animals
;
Brain*
;
Endothelium*
;
Mannitol*
;
Perfusion*
;
Rats*
2.A Case of Recurrent Expansile Cyst Formation after Gamma Knife Radiosurgery for a Cerebral Arteriovenous Malformation: Role of the Residual Nidus: Case Report.
Won Kil BOK ; Kyung Soo MIN ; Mou Seop LEE ; Yang KWON
Journal of Korean Neurosurgical Society 2003;33(1):76-80
The authors report a case of recurrent expansile cyst formation after gamma knife radiosurgery(GKRS) for a cerebral arteriovenous malformation where the residual nidus might play an important role. A 28-year-old male patient underwent gamma knife radiosurgery for a left parietal lobe arteriovenous malformation which had manifested with generalized tonic-clonic seizure in November 1992. In March 1999, 76 months after GKRS, the patient presented with headache, dysphasia and right hemiparesis and the computed tomography(CT) and magnetic resonance(MR) image revealed a huge cystic lesion with enhancing nodule at the anterior wall of the cyst. Cerebral angiography showed a small residual nidus. Aspiration and drainage of the cystic fluid via a burr hole was performed and the symptoms improved. One year later, in March 2000, the symptoms recurred, and CT and MR image revealed a new huge cystic lesion anterior to the enhancing nodule. Surgical removal of the residual nidus was performed, and there is no recurrence of the cyst for two years till now.
Adult
;
Aphasia
;
Arteriovenous Malformations
;
Cerebral Angiography
;
Drainage
;
Headache
;
Humans
;
Intracranial Arteriovenous Malformations*
;
Male
;
Paresis
;
Parietal Lobe
;
Radiosurgery*
;
Recurrence
;
Seizures
3.Clinical Trials of Tavegyl in Dermatologic Field.
Choong Sang KIM ; Jai Il YOUN ; Yoo Shin LEE ; Soon Bok LEE ; Yang Ja PARK ; Dong Kil BYUN ; Won HOUH
Korean Journal of Dermatology 1974;12(2):33-37
Clinical trials were done to obtain ifnormation on the clinical efficacy, tolerance and side effects of a new antihistarnine, Mecloprodine(Tavegyl), in various skin disordetrs. A total of 48 patients suffered from various skin disorders as urticaria, eczema etc. v ere treated with 2mg. daily for 3 days to 15 days according to state of disorders. The results are as follows. 1. Improvement was noticed in 79.2% of total patients(38/48). 2. Tavegyl was efiective in all 8 cases of acute urticaria and most cases(7/8) of urticaria factitia. 3. Among 19 cases of chronic urticaria, improvement was noticed in 13 cases(68. 49). Improvement was alsa noticed in all 6 cases of eczema. 5. Drowsiness and weakness cccurred in 6.2% of cases(3/48).
Clemastine*
;
Eczema
;
Humans
;
Skin
;
Sleep Stages
;
Urticaria
4.The Effects of Aircraft Noise Exposure upon Hearing Loss, Anxiety, and Depression on Subjects Residing Adjacent to a Military Airbase.
Yu Rim JEONG ; Jae Beom PARK ; Kyoung Bok MIN ; Chan LEE ; Hyun Gwon KIL ; Won Wook LEE ; Kyung Jong LEE
Korean Journal of Occupational and Environmental Medicine 2012;24(1):40-51
OBJECTIVES: To determine the level of aircraft noise exposure and how it relates to hearing loss, and to investigate the association between noise exposure and anxiety and depression in subjects residing adjacent to a military airbase. METHODS: The study was conducted upon 898 inhabitants between the ages of 30-79, living near the military airbase in Jeonra-do. The subjects were divided into three noise-exposure groups: high-exposure, low-exposure, and a control group. The cut-values were 80 and 60 on the Weighted Equivalent Continuous Perceived Noise Level scale. A self-administered questionnaire including the Beck Anxiety Inventory (BAI) and the Beck Depression Inventory (BDI) were completed. Pure tone audiometry tests were performed. RESULTS: Hearing loss prevalence was defined by a >40 dB loss in bilateral ears or in one ear; the difference of <15 dB compared to the better side was 30.8%. The mean BAI/BDI score was 18.9+/-14.3/18.7+/-11.6, the number of abnormal subjects with BAIs > or =22 was 317 (35.3%), with BDIs > or =21 was 347 (38.6%). The pure tone average, BAI, and BDI scores were higher in the noise-exposure groups compared to the control. The BAI/BDI abnormal subjects showed a higher hearing threshold shift level compared to the normal scored subjects. The odd ratios for anxiety was significantly high in both noise exposure groups and the hearing loss, for depression was significantly high in high-exposure group and hearing loss. CONCLUSIONS: Anxiety and depression were higher when exposure to high-level noise and further complicated by hearing loss. Further investigation is needed to determine the cause-effect relationship.
Aircraft
;
Anxiety
;
Audiometry
;
Depression
;
Ear
;
Hearing
;
Hearing Loss
;
Humans
;
Military Personnel
;
Noise
;
Prevalence
;
Questionnaires
5.Cranioplasty Using Frozen Autologous Bone.
Won Kil BOK ; Suk Ki HONG ; Kyung Soo MIN ; Mou Seop LEE ; Young Gyu KIM ; Dong Ho KIM
Journal of Korean Neurosurgical Society 2003;33(2):166-169
OBJECTIVE: Variable materials have been used in cranioplasty of skull defects, of which autologous bone is the most ideal. The authors explore methods and clinical results of cranioplasty with frozen autologous bone. METHODS: Cranioplasty was performed using frozen autologous bone in 16 patients with skull defects between August 1997 and April 1999. Primary diseases were severe head injury in 14 patients and cerebral infarction in two patients, and all of them received decompressive craniectomy. Cranioplasty were done from 25 to 225 days after primary operation. The mean follow-up period was 34 months. RESULTS: There was no infection or epidural hematoma. During the follow-up period, autologous bone flap were fused firmly to the skull without absorptive evidences and delayed complications. It was satisfactory in all cases when considered aesthetic aspects. CONCLUSION: Cranioplasty using frozen autologous bone is safe and satisfactory method for repair of surgically induced skull defects.
Cerebral Infarction
;
Craniocerebral Trauma
;
Decompressive Craniectomy
;
Follow-Up Studies
;
Hematoma
;
Humans
;
Skull
6.Effects of Propofol-Fentanyl and Propofol-Ketorolac Anesthesia on Postoperative Nausea and Vomiting after Strabismus Surgery in Children.
Hae Keum KIL ; Won Oak KIM ; Jong Bok LEE ; Jung Yeon HONG ; Myung Eun KIM
Korean Journal of Anesthesiology 1998;34(5):984-990
BACKGROUND: Strabismus surgery is associated with a high incidence of postoperative nausea and vomiting. Propofol is an anesthetic which has an antiemetic effect. A randomized study was done to compare the efficacy of propofol-fentanyl and propofol-ketorolac anesthesia for strabismus surgery in children. METHODS: Eighty-five children, ASA physical status I or II, for strabismus surgery, were studied. Patients were randomly assigned to one of two groups by picking the envelop. Preanesthetic medication was not given. Fentanyl group received fentanyl 1.5 microgram/kg i.v. and ketorolac group received ketorolac 1 mg/kg, 2 minutes before induction. Atropine was given after that. Anesthesia was induced with propofol 2.4 mg/kg and vecuronium 1 mg/kg and intubation was performed. Anesthesia was maintained with a three-stage infusion technique of propofol (12 mg/kg/hr for 1st 10 minutes, 9 mg/kg/hr for 2nd 10 minutes and 6 mg/kg/hr was followed) with oxygen and nitrous oxide. Ketorolac was injected intramuscularly for preemptive analgesia immediate after induction. The incidence of nausea and vomiting was evaluated for postoperative 48 hours. And also, intraoperative oculocardiac reflex was monitored to compare the difference between two groups. RESULTS: During postoperative 48 hours, fentanyl group and ketorolac group had a similar low incidence of nausea and vomiting (4.2% and 7.0%). There is no significant difference of intraoperative oculocardiac reflex between two groups (45.2% and 30.2%). CONCLUSIONS: Propofol administered to induce and maintain anesthesia with a three-stage infusion technique is equally effective in preventing postoperative nausea and vomiting in propofol-fentanyl and propofol-ketorolac anesthesia for strabismus surgery in children.
Analgesia
;
Anesthesia*
;
Antiemetics
;
Atropine
;
Child*
;
Fentanyl
;
Humans
;
Incidence
;
Intubation
;
Ketorolac
;
Nausea
;
Nitrous Oxide
;
Oxygen
;
Postoperative Nausea and Vomiting*
;
Preanesthetic Medication
;
Propofol
;
Reflex, Oculocardiac
;
Strabismus*
;
Vecuronium Bromide
;
Vomiting
7.A Case of Sclerosing Peritonitis Successfully Treated with Corticosteroid Therapy.
Su In YOON ; Hye Young KIM ; Min Ok KIM ; Hag Ei KIM ; Ki Won MOON ; Joung Ho HAN ; Jisook HAHN ; Hoe Bok CHAI ; Soon Kil KWON ; Il Hun BAE
Korean Journal of Nephrology 2004;23(1):169-173
Sclerosing peritonitis is a rare but fatal complication of peritoneal dialysis (PD). Management of sclerosing peritonitis includes cessation of PD, total parenteral nutrition, and surgery. Recently, a few reports have indicated immunosuppression might be beneficial in sclerosing peritonitis. In these reports, all of patients had the combination therapy of steroid and immunosuppressant. A 37-year old man develped sclerosing peritonitis 3 months after switching from PD to hemodialysis because of uncontrolled peritonitis. An abdominal computed tomography (CT) scan demonstrated massive ascites with multilocuated fluid collection and extensive enhancement of the peritoneum. A peritoneal biopsy showed proliferation of fibrous collagenous tissue with infiltration of lymphocytes. We started corticosteroid for one month. A follow-up CT scan showed complete resolution with absence of peritoneum thickness and fluid collection 16 months after corticosteroid therapy. The patient currently remains free of symptoms in an outpatient hemodialysis unit. To our knowledge, this is the first case of sclerosing peritonitis successfully treated with corticosteroid therapy alone in Korea.
Adult
;
Ascites
;
Biopsy
;
Collagen
;
Follow-Up Studies
;
Humans
;
Immunosuppression
;
Korea
;
Lymphocytes
;
Outpatients
;
Parenteral Nutrition, Total
;
Peritoneal Dialysis
;
Peritoneum
;
Peritonitis*
;
Renal Dialysis
;
Tomography, X-Ray Computed
8.Brain MRI Findings of Spontaneous Intracranial Hypotension.
Won Kyu PARK ; Woo Mok BYUN ; Yang Gu JOO ; Jae Ho CHO ; Kil Ho CHO ; Mi Soo HWANG ; Bok Hwan PARK ; Sang Jin LEE
Journal of the Korean Radiological Society 1997;37(3):385-391
PURPOSE: To evaluate brain MRI findings of spontaneous intracranial hypotension. MATERIALS AND METHODS: A retrospective review of MRI findings was conducted on six patients with clinically proven spontaneous intracranial hypotension ; no patient had history of previous spinal puncture. Follow-up MRI was available in two patients, and to detect CSF leakage, radionuclide cisternography (n=5), myelography (n=1), and MR myelography (n=1) were performed. RESULTS: On contrast-enhanced T1WI, diffuse dural enhancement was seen in all cases, subdural hematoma or hygroma was seen in four cases, pituitary gland prominence in four, dural sinus dilatation in four, downward displacement of cerebellar tonsil in two, downward displacement of iter in one, and suprasellar and prepontine cistern effacement in two. In no patient was abnormal CSF leakage found. CONCLUSION: Although dural enhancement, as seen on MRI, is not specific, diffuse enhancement of dura matter accompanying by subdural hematoma, hygroma, pituitary gland prominence, dural sinus dilatation, downward displacement of the cerebellar tonsil, or suprasellar and prepontine cistern effacement can strongly suggest intracranial hypotension.
Brain*
;
Dilatation
;
Follow-Up Studies
;
Hematoma, Subdural
;
Humans
;
Intracranial Hypotension*
;
Lymphangioma, Cystic
;
Magnetic Resonance Imaging*
;
Myelography
;
Palatine Tonsil
;
Pituitary Gland
;
Retrospective Studies
;
Spinal Puncture
9.MRI and CT Findings of Intracranial Neurosyphilis.
Hong Kil SUH ; Ya Seong SHIM ; Seon Bok KIM ; Uk Jung KIM ; Shin Ho LEE ; Hae Kyuong JUNG ; Eil Seong LEE ; Ik Won KANG ; Hyeun Cha CHO
Journal of the Korean Radiological Society 1999;40(2):205-209
PURPOSE: To evaluate the CT and MRI findings of neurosyphilis. MATERIALS AND METHODS: We retrospectivelyreviewed the CT and MR imaging findings in five patients with intracranial neurosyphilis confirmed by CSF, VDRL,TPHA, and clinical follow-up. MR imaging was performed in all five cases, and CT in two. RESULTS: The MRI and CTfindings of intracranial neurosyphilis included infarction (n=3), focal inflammation (n=1) and encephalopathy(n=1). There was a total of ten infaretions : three of the basal ganglia, two each of the frontal lobe, watershedzone, and cerebellum, and one of the occipital lobe. Intaretion was most common in MCA territory (n=9; 50%),followed by the watershed zone (16.6%), posterior cerebral artery territory (16.6%), and posterior inferiorcerebellar artery territory (11.1%), The size of the lesion varied from 1cm to larger than one lobe. One patientshowed diffuse high signal intensity in the left temporal lobe, but on follow-up MRI, this had resolved. CONCLUSION: The most common finding of neurosyphilis, as seen on MRI and CT, was infarction in middle cerebralarterial territory.
Arteries
;
Basal Ganglia
;
Cerebellum
;
Follow-Up Studies
;
Frontal Lobe
;
Humans
;
Infarction
;
Inflammation
;
Magnetic Resonance Imaging*
;
Neurosyphilis*
;
Occipital Lobe
;
Posterior Cerebral Artery
;
Syphilis
;
Temporal Lobe
10.Treatment Effects of MIN GLASSES for Amblyopia and Diplopia.
Byung Moo MIN ; Kil Hwan KO ; Sang Jin KIM ; Myung Mi KIM ; Yeoung Geol PARK ; Soo Chul PARK ; Chan PARK ; Jong Bok LEE ; Hyo Sook AHN ; Se Oh OH ; In Gun WON
Journal of the Korean Ophthalmological Society 1996;37(3):533-540
MIN GLASSES is specially manufactured in order to enhance satisfaction of wearer and therefore increase the effectiveness of treatment of an amblyopia and a diplopia. One of the lens is specially grounded and coated to blur vision. Cosmetically, the eye appears to wear regular glasses through the blur lens. We prospectively studied 58 amblyopic children and 10 diplopic adults. Each patient was treated with MIN GLASSES for cosmetic problems. We checked linear visual acuity of pre- and post-treatment. Questionnaires were given to the patients and parents regarding cosmetic satisfaction with treatment. In amblyopic children. 44 patients(75.9%) showed visual acuity improvement of 1.61 +/- 1.50 lines by Han's visual acuity chart. Patient compliance was 87.9%(51 patients) with patient satisfaction based on a questionnaire response. Parents were 87.9%(51 parents) positive response. In diplopic adults, 10 patients(100%) were positive response with satisfaction and demonstrated to be free of symptom of diplopia. MIN GLASSES is effective in high compliance satisfaction of amblyopia and diplopia, and improvement of visual acuity of amblyopia.
Adult
;
Amblyopia*
;
Child
;
Compliance
;
Diplopia*
;
Eyeglasses*
;
Glass*
;
Humans
;
Parents
;
Patient Compliance
;
Patient Satisfaction
;
Prospective Studies
;
Surveys and Questionnaires
;
Visual Acuity