1.A Case of Maffucci's Syndrome
The Journal of the Korean Orthopaedic Association 1972;7(2):249-252
A case of Maffucis syndrome is presented with a brief review of literature because of its rarity. An attempt was made for reconstructive surgery for the deformities involving right hand with rewarding result.
Congenital Abnormalities
;
Hand
;
Reward
2.Clinical Observation in 171 Cases of Electrical Burn Patients
The Journal of the Korean Orthopaedic Association 1973;8(1):19-28
During the past 11 years period from April, 1961 to March, 1972 171 cases of electrical burn patients were treated at Orthopedic Department of Han-Il Hospital. The author reviewed and discussed our clinical experience of electrical thermal injuries. Clinical analysis of these 171 cases of electrical burn patients was carried out and summarized as follows; 1) The majority of the patients ranged two to three decades of life(68.4%); The youngest 1 year old and oldest 53 years of age. Male were involved significantly more than female, the incidence being 163 cases (95.3%) and 8 cases. 2) Seasonal distribution showed more than about two third with 114 cases for rainy summer times and Autumn from May to October. 3) Among 171 cases of electrical burn patients, 131 patients (54.2%) were under 5% of body surface and 15 patients (11.3%) were over 20% of body surface. 4) In the regional distribution of burn wound, the upper extremity were 157(92.3%), 73(42.9%) in lower extremity, and 49 (28.9%) in other region. 5) Occupational distribution; The electrical line man and electrician were seen 136 cases (80%) which is two third of 171 patients, labor 12 cases(7%), 10 cases (5.9%) in painters, 8 cases (4.6%) in company employee and industrialist, 5 cases (2.9%) in house-wife, and 4 cases (2.4%) in motor man. 6) The most frequently early complication at electric burn of 171 cases were gastrointestinal symptom 111 cases (65%), fracture 18 cases (10.5%), head injuries (intracranial bleeding and basal bone fracture of skull) 15 cases (6.4%), spinal cord injury and kidney rupture 1 cases (0.6%), hemorrhage 2 cases (1.2%), and other 8 cases (4%). 7) The predominating organisms cultured out of burn wounds of 26 cases were staphylococcus aureus 9 (34.7%), pseudomonas auerginosa 5 (19.2%), E. coli 3 (11.5%), staphylococcus albus 1(4%), β-hemolytic streptococcus 1 (4%), and no growth were 7 (26.9%). 8) The type of current and the voltage in 102 cases among the 171 cases of electric burn patients was clear. Injury of the 99 cases out of the 102 cases were by indirect current and the 3 was by direct current. In 99 cases by indirect current, electric burn in accordance with high tension current in voltage was 81 cases (79.4%), low tension current injuries 18 cases (17.6%). 9) At the admission, laboratory findings of the electric burn patients showed hemoconcentration and leukocytosis. 10) Early excision of the necrotic tissue and skin grafting was performed in 94 times. The results was excellent in 71 times. 11) Among 171 cases of electric burn patients, later complication were seen 47 cases (27.4%), which is 25 cases (14.3%) in amputation, 8 cases in cicatrical contraction, 4 cases in serum hepatitis, 4 cases in paralysis, 2 cases in osteomyelitis, 2 cases in ankylosis of knee joint, 2 cases in drop foot, 1 case in anal stricture, and 1 case in cataract. 12) The overall motality in this series was 8% (14cases) and the most frerent cause of the death was due to head injury (9 cases) at the time of electrical burn injuries.
Amputation
;
Ankylosis
;
Burns
;
Burns, Electric
;
Cataract
;
Constriction, Pathologic
;
Craniocerebral Trauma
;
Female
;
Foot
;
Fractures, Bone
;
Hemorrhage
;
Hepatitis
;
Humans
;
Incidence
;
Kidney
;
Knee Joint
;
Leukocytosis
;
Lower Extremity
;
Male
;
Orthopedics
;
Osteomyelitis
;
Paralysis
;
Pseudomonas
;
Rupture
;
Seasons
;
Skin Transplantation
;
Spinal Cord Injuries
;
Staphylococcus
;
Staphylococcus aureus
;
Streptococcus
;
Upper Extremity
;
Wounds and Injuries
3.Changes of Nuchal Translucency in Early Normal Fetuses.
Korean Journal of Obstetrics and Gynecology 2000;43(6):998-1001
OBJECTIVE: To examine a normal range for nuchal translucency thickness between 9 and 14 weeks' gestation in normal fetuses. METHODS: Nuchal translucency was measured prospectively in 124 fetuses between 9 and 14 weeks' gestation resulted in normal pregnancy outcome. The nuchal translucency measurement was expressed as the median and the 5th, 25th, 75th, and 95th percentiles according to complete weeks of gestation based on ultrasound measurement. RESULTS: The median nuchal translucency thickness was 1.8 mm at 9 weeks' gestation and it declined to 1.6 mm at 10 weeks. But the median thickness increased from 1.95 mm at 11 weeks to 2.3 mm at 12 weeks, after which it slightly declined to 2.25 mm at 13 weeks. And then it increased to 2.5 mm at 14 weeks. A nuchal translucency thickness greater than 2.5 mm was not found at 9 and 10 weeks' gestation, but found in 21.8% of fetuses from 11 weeks to 14 weeks. CONCLUSION: In normal fetuses, there is a physiologic variation in the thickness of nuchal translucency between 9 and 14 weeks' gestation. The calculation of risk for trisomies based on this thickness should take this variation into account. The adoption of a gestational age-dependent cutoff point, based on the deviation of a given measurement from the median, may reduce the invasive procedure for karyotyping. And this study suggest that if the nuchal translucency measurement is greater than 2.5 mm before 10 weeks, it may advise the karyotyping.
Female
;
Fetus*
;
Karyotyping
;
Nuchal Translucency Measurement*
;
Pregnancy
;
Pregnancy Outcome
;
Prospective Studies
;
Reference Values
;
Trisomy
;
Ultrasonography
4.Body fat distribution and hypertension.
Korean Journal of Preventive Medicine 1991;24(1):57-69
This study examined the cross-sectional association of body fat distribution with hypertension as well as the superiority of medical calf skinfold measured as peripheral fat distribution over the conventional triceps skinfold using 450 Korean Navy divers selected by authors' convenience in 1990. Their mean age was 27.9 and range of it was 19-51. The centrally located body fat was approximated by subscapular from these skinfold measures to reflect central versus peripheral fat distribution pattern: 2 ratios and 2 differences. After controlling age and overall obesity (body mass index), prevalence odds ratios of the 2/4, 3/4, 4/4 quartiles of subscapular skinfold comparing with lowest 1/4 quartile were 2.05 (95% confidence interval, CI 1.18-3.59), 2.02 (95% CI 1.06-3.86), 4.00 (95% CI 1.99-8.06) respectively. The difference of subscapular and medical calf skinfolds was associated with hypertension (odds ration 2.45, 95% CI 1.28-4.68 comparing highest with lowest quartiles). Triceps and medical calf skinfolds alone did not show any odds ratio not including unity. The adjusted odds ratios were generally reduced in small magnitude compared with crude odds ratios not adjusted for age and overall obesity. The medical calf skinfold appeared to be more representative of peripheral body fat distribution than triceps skinfold. These findings suggest that central fat distribution rather than peripheral distribution is associated with hypertension independent of age and overall level of obesity and medical calf skinfold may replace conventional triceps skinfold in predicting peripheral distribution of body fat.
Adipose Tissue*
;
Body Fat Distribution*
;
Hypertension*
;
Obesity
;
Odds Ratio
;
Prevalence
5.polypoidal Choroidal Vasculopathy.
Journal of the Korean Ophthalmological Society 2000;41(12):2573-2584
No Abstract Available.
Choroid*
6.A case of varicella during pregnancy complicating fetal death in utero.
Korean Journal of Obstetrics and Gynecology 1991;34(4):583-588
No abstract available.
Chickenpox*
;
Fetal Death*
;
Pregnancy*
7.Effect of Coculture System with Autologous Cumulus Cells on Embryo Quality and Pregnancy Rates.
Korean Journal of Fertility and Sterility 1998;25(3):299-304
Despite the rapid development of assisted reproductive technologies (ART) in recent years, implantation rates after replacement of embryos into the uterine cavity remains low. Several techniques such as culture conditions based on formulations of human tubal fluid and various ART techniques as GIFT, ZIFT, TET have been adopted in recent years to improve embryo viability in vitro and implantation rates. Also, coculture of human IVF-derived embryos have been used in an effort to increase the number of viable embryos following IVF and to improve synchrony between the developing embryo and the uterine environment. The aim of this study was to evaluate whether the use of coculture with autologous cumulus cells has a significant beneficial effect on the development of embryos in vitro and its relation to the pregnancy rates in 120 patients with previous failed IVF-ET from September, 1995 to January 1998. We obtained the results from which significant improvement in the quality of viable embryos were observed using a coculture system with autologous cumulus cells, but pregnancy rates in this group of patients did not differ from the rate in the standard IVF group during the same period. Our study shows that a simplified short-term coculture system with autologous cumulus cells may help rescue moderate quality embryos to cleave regularly.
Coculture Techniques*
;
Cumulus Cells*
;
Embryonic Structures*
;
Humans
;
Pregnancy Rate*
;
Pregnancy*
;
Reproductive Techniques, Assisted
;
Zygote Intrafallopian Transfer
8.The effect of azelaic acid and retinoic acid on epidermal melanocytes in UVB-irradiated black mice.
Kyung Won HAN ; Ki Hong LEE ; Ki Bum MYUNG
Korean Journal of Dermatology 1992;30(4):492-498
Increased melanin pigmentation following ultraviolet irradiat.ion is due to increasing tyrosinase activity and multiplicatian of functioning melanocytes. After UV-irradiation, the size of melanocytes increases, and melanocyte dendrites elongatc, and branch. In this experiment, we induced the activation of melanocyts in the epidermis of C57BL black mice by ultraviolet-B(UVB) irradiation and observcd ihe effect of azelaic acid and retinoic acid on the UVB activated epidermal melanocytes. Sixty C57BL black mice were irradiated by UVB 100mJ/cm daily for 10 days, and then azeiaic acid and retinoic acid were topically applied daily for 7 weeks. For the estimation of morphologic change of epidermal melanocytes, light microscopic observation with split DOPA stain was performed at the end of the 1st, 3rd, 5th and 7th week of topical application. The results are summerized as follows : 1. The number, size and circumference of DOPA-positive epidermal melanocytes were significantly decreased in 20% azelaic acid applied group and 30% azelaic acid and 0.05% retinoic acid applied group. 2. In 20% azelaic;i.cid and 0.05% retinoic acid applied group, the number, size and circumference of DOPA-positive epidermal melanocytes were nore significantly decreased than in 20% azelaic acid applied group. In summary, the present study suggets that azelaic acid act as a depigmenting agent on epidermal melanocyte; and such depigmenting effect of azelaic acid was increased by addition of retinoic acid.
Animals
;
Dendrites
;
Dihydroxyphenylalanine
;
Epidermis
;
Melanins
;
Melanocytes*
;
Mice*
;
Monophenol Monooxygenase
;
Pigmentation
;
Tretinoin*
9.A Case-Control Study on Risk Factors of Preterm Labor.
Chang Ik LEE ; Kyung Sim KOH ; Won Ki LEE
Korean Journal of Obstetrics and Gynecology 1997;40(8):1619-1629
BACKGROUND: The prevention of preterm deliveries still remains a major problem in ob-stetrics. The cause of preterm labor is poorly understood. Our purpose was to determine the risk factors for preterm labor associated with specific clinical and environmental factors. METHODS: Using a case-control design, 54 women with preterm labor and 134 controls with term labor, who were admitted to the department of Obstetrics and Gynecology, Dan- kook University Hospital from January, 1996 to August, 1996. The study groups were inte- rviewed and their medical records were reviewed. RESULTS: 1. There were no significant differences of maternal age, maternal weight at 20 weeks of gestation and maternal weight gain at the time of delivery. 2. There were no significant differences between housewives and working women. But the physical workload of the preterm labor group was significantly higher than the control group ( 16.0% vs. 4.0% ). 3. There were no significant differences in the smoking habit of mother or her husba- nd. The passive smoking of the preterm labor group was significantly higher than the con- trol group ( 43.8% vs. 26.8% ). 4. In vaginal bleeding at pregnancy, the preterm labor group was significantly higher than the control group ( 15.7% vs. 2.3% ). Especially, the third trimester vaginal bleeding of the preterm labor group was significantly higher than the control group. 5. There were no significant differences in the number of previous fullterm deliveries, previous abortions, and living children between two groups. The experience of the previous preterm deliveries of the preterm group was significantly higher than the control group ( 11. 5% vs. 0.8% ). 6. There were no significant differences of medications, consumption of alcohol, coffee, tea, green-tea, cola and nutritional beverages, the experiences of coitus, defecation numbers and accidents during pregnancy between two groups. 7. There were no significant differences in the plasma concentrations of hemoglobin, hematocrit, white blood cells, and in the blood pressure, and the body temperature between two groups. CONCLUSION: The risk factors of preterm labor were severe physical workload, vaginal bleeding at pregnancy, especially, the third trimester vaginal bleeding, and the experience of previous preterm deliveries.
Abortion, Induced
;
Beverages
;
Blood Pressure
;
Body Temperature
;
Case-Control Studies*
;
Child
;
Coffee
;
Coitus
;
Cola
;
Defecation
;
Female
;
Gynecology
;
Hematocrit
;
Humans
;
Leukocytes
;
Maternal Age
;
Medical Records
;
Mothers
;
Obstetric Labor, Premature*
;
Obstetrics
;
Plasma
;
Pregnancy
;
Pregnancy Trimester, Third
;
Risk Factors*
;
Smoke
;
Smoking
;
Tea
;
Tobacco Smoke Pollution
;
Uterine Hemorrhage
;
Weight Gain
;
Women, Working
10.Hemorrhagic Shock and Encephalopathy Syndrome as a Cause of Sudden Death in Infants.
Jong Won LEE ; Chang Han LEE ; Ki Sup CHUNG
Journal of the Korean Pediatric Society 2000;43(6):814-819
PURPOSE: To evaluate the clinical characteristics, treatments and outcome of patients with hemorrhagic shock and encephalopathy(HSE) syndrome. METHODS: We performed a clinical study on 14 patients who were diagnosed as hemorrhagic shock and having encephalopathy syndrome in the Department of Pediatrics, from 1984 to 1998. Age, sex, clinical symptoms and physical findings at admission, the most deranged laboratory findings, radiologic findings, treatments and outcome were analyzed. RESULTS: The age of onset was 1.0+/-0.9 years and the male to female ratio was 1: 1.8. At admission, clinical findings included dehydration in 85.7%, shock in 85.7%, fever in 71.4%, vomiting in 71.4%, diarrhea in 64.3%, GI bleeding in 50%, convulsion in 42.9%, and edema in 35.7%. Altered mental state was found in 100%, hepatomegaly in 64.3%, and splenomegaly in 21.4%. Laboratory findings revealed D-dimer positive in 92.9%, the mean hemoglobin level 8.2+/-2.1g/dL, BUN 35.7+/-24.0mg/dL, creatinine 1.9+/-1.5mg/dL, AST 561.0+/-1,412.1IU/L, ALT 858.9+/-1,649.8IU/L, blood glucose 229.5+/-197.4mg/dL, ammonia 195.4+/-129.7pg/dL, and total bilirubin 4.9+/-8.2mg/dL. On serologic tests, rotavirus and Epstein-Barr virus was found in 1 patient(7.1%), respectively. The mortality rate was 78.6%. CONCLUSION: We found that shock and disseminated intravascular coagulation(DIC) played important roles in the pathogensis of HSE syndrome, and encephalopathy, hepatic and renal insufficiency, and respiratory failure were secondary complications resulting from shock and DIC. Despite vigorous treatment, the prognosis was very poor. We feel more efforts should be focused on investigating the etiology and pathophysiology of HSE to prevent as well as develop a specific therapy. (J Korean Pediatr Soc 2000;43:814-819)
Age of Onset
;
Ammonia
;
Bilirubin
;
Blood Glucose
;
Creatinine
;
Dacarbazine
;
Death, Sudden*
;
Dehydration
;
Diarrhea
;
Edema
;
Female
;
Fever
;
Hemorrhage
;
Hepatic Encephalopathy
;
Hepatomegaly
;
Herpesvirus 4, Human
;
Humans
;
Infant*
;
Male
;
Mortality
;
Pediatrics
;
Prognosis
;
Renal Insufficiency
;
Respiratory Insufficiency
;
Rotavirus
;
Seizures
;
Serologic Tests
;
Shock
;
Shock, Hemorrhagic*
;
Splenomegaly
;
Vomiting