Multiple, reticulated, dark brown colored, macules and patches suddenly developed on the fac, and neck of a 48-year-old Korean woman two days after a traffic accident. On physical examination and laboratory tests including serum melanocyte-stimulating hormone, estrogen and progesterone level, no abnormalities were found except cervical pain. Histological examination of hematoxylin-eosin stained sections revealed increased melanin pigmentation in the basal layer, but the number of melanocytes was not changed in DOPA stained section. Topical application of 2% hydroquinone and 20% azelaic acid ointments had been applied successively for two months each without any apparent improvement. Herein we present a case of reticulate hyperpigmentation on the face and neck, which is very acute and whose causative factors are not certain.
Accidents, Traffic ; Dihydroxyphenylalanine ; Estrogens ; Female ; Humans ; Hyperpigmentation* ; Melanins ; Melanocytes ; Middle Aged ; Neck Pain ; Neck* ; Ointments ; Physical Examination ; Pigmentation ; Progesterone

Tolerance to contact hypersensitivity was induced by feeding of different DNCB doses in mice. A total of 40 mice were divided into 4 groups(control group, 6 mg feeding group, 10 mg feeding group, 14 mg feeding group) in experiment I, Degree of tolerance to contact hypersensitivity was rneasured by incremert rate of ear swelling after challenge with DNFB. Experiment 2 was performed in the same method of cxperiment: I with addition of 3 mg DNCB feeding group. The increment ratee were significantly decreased in DNCB feeding groups in experirnent 1 and 2(p<0.0l). But there were no differences statisticalIy between increment rates of DNCB feeding groups.
Animals ; Dermatitis, Contact ; Dinitrochlorobenzene* ; Dinitrofluorobenzene ; Ear ; Mice*

No abstract available.
Gangwon-do* ; Hepacivirus* ; Hepatitis C* ; Hepatitis* ; Liver Diseases* ; Liver* ; Prevalence*

No abstract available.

We present herein a case of pyodcrma gangrenosum, who showed good response to clofazimine therapy. The patient, 19-year-old male, had suffered from chronic diarrhea for 10 months before the rapidly spreading pustules and ulcers with undermined purple-to-red borders devkloped on his both lower and upper extremitics. Clofazimine was given orally in a dose of 100mg three times daily for 16 days, and tapered to 100 mg two times daily for the next 11 days. Clinical improvement was noted after 7 day's treatment and the almost all of the skin lesiors were replaced by granulation tissue with epithelizatiori or crust formation after 6 days treatment.
Clofazimine* ; Diarrhea ; Granulation Tissue ; Humans ; Male ; Pyoderma Gangrenosum* ; Pyoderma* ; Skin ; Ulcer ; Young Adult

We present herein a case of human infestation of canine scabies occuring in a 7l-year-old female patient. Severe pruritic, erythematous papular lesions and excoriation were found over the abdomen, submammary area, and thigh. The itching sensation was aggravated especially at night. Efforts to demonstrate mites from the lesiona of the patient were unsuccessful. Her pet, a small puppy, showed loss of hair and crusted or scaly erythematous patches on the auricles and trunk 1 month prior to her skin lesions. Sarcaptescabiei var. canis were collected from the puppy by brushing the hair snd crusted or scaly patches on its skin. The patient and puppy were treated successfully with application of 25% benzyl benzoate solution.
Abdomen ; Benzoates ; Female ; Hair ; Humans* ; Mites ; Pruritus ; Scabies* ; Sensation ; Skin ; Thigh

Various stem cells or progenitor cells are being used to treat cardiovascular disease. In ischemic heart disease, stem cell therapy is expected to regenerate damaged myocardium. To evaluate effects of stem cell treatment, the method to image stem cell location, distribution and differentiation is necessary. Optical imaging, MRI, nuclear imaging methods have been used for tracking stem cells. The methods and problems of each imaging technique are reviewed.
Cardiovascular Diseases* ; Magnetic Resonance Imaging ; Myocardial Ischemia ; Myocardium ; Optical Imaging ; Stem Cells*

A 2-month-old Korean boy presented with a solitary papule on the cheek which was noted at birth. Histopathologic findings were consistent with angiofibroma of fibrous papule of the face (FPF). FPF is known to affect adults, and congenital occurrence has not been reported to the best of our knowledge. We report a case of congenital FPF which showed a facial papule clinically and an angiofibroma histologically.
Adult ; Angiofibroma ; Cheek ; Humans ; Infant ; Male ; Parturition

No abstract available.
Dialysis* ; Peritonitis* ; Salmonella*

No abstract available.
Dialysis* ; Peritonitis* ; Salmonella*