Alopecia areata(AA) is a common dermatologic disease, the origin of which is still unknown. At least, it has been associated with some genetic influences in the etiopathogenesis. We have now evaluated AA patients to study the actual association of the genetic role by fingerprint analysis. The incidences of six or more arches were determined in 74 female and 86 male patients excluding alopecia totalis and universalis, and in healthy 167 female controls, based on Selmanowitz's thesis (1974). The results of this study are follows: 1. The difference between the frequency in AA patients(7. 5%) and in controls (3.3%) reaches the statistical significance(p<0.05 by x2-test). 2. The association of genetic background in AA is strengthened in the group of female patients(p<0. 01), recurrent episode(p<0.01). and multiplex farm (p<0.01). 3. Twenty patients(12. 5%) have family history. The incidence in 3(15.0%) of these patients is considerably common but not statistically significant. A correlation of biologic relevance and family predisposition in AA is not precluded. 4. The frequency of arches in patients and in controls is increased on both second fingers and decreased on both fourth fingers. It is more common on both second and left third fingers in female patients. The incidence of arches averages about 6 67% in patients and 4. 58% in controls.
Alopecia Areata* ; Alopecia* ; Dermatoglyphics* ; Female ; Fingers ; Humans ; Incidence ; Male

No abstract available.
Travel Medicine

No abstract available.
Mediastinum* ; Osteosarcoma*

Emergency nursing intervention should be provided to patients under fatal status with much quickness and accuracy. To improve the quality of emergency medical service, triage nurse systems, being implemented in advanced hospitals which successfully provide effective emergency services, are considered in this thesis. A triage nurse is defined as a nurse who first and immediately meets the patient at the very entrance of emergency department, and performs proper intervention according to the extent of injury. Triage functions include interviewing patients, physical evaluation, classifying patients, assigning nurses/doctors, and beds, performing preliminarily required tests and remedies, re-evaluation of waiting patients, emotional supports, arranging future medical services, and education. In Korea, triage nurse systems have not yet been introduced, however, some prleminary types of triage systems are being practised. The purpose of this thesis was to review the triage functions implemented in Korean emergency department and then to suggest a model of triage nurse system for Korean emergency departments. For field study, 10 emergency departments in Seoul, which have more than 13 nurses, are selected, and a nurse who have more than 1 year experience in emergency department was interviewed from each workshift, i.e. day, evening, and night. Data collection taken 17 days from Apr. 8 to Apr. 30, 1996. In the field study, we reviewed the triage functions performed in Korean emergency departments. 40.9% of interviewed nurses show that the triage functions are performed by general nurses, 18.42% and 10.15% indicate that the functions were performed by charge nurses and assigned nurses, respectively. Thus, triage nurse systems where pre-assigned nurses consistently perform triage functions were not yet introduced in Korean emergency departments. However, 96.7% of the nurses answered that triage systems are needed in their emergency departments and 82.77% showed that triage functions would be performed at the entrance of emergency department. A triage nurse systems will unload stresses which both patients and supporters cope with, provide secure and comfortable medical environments, and reduce the waiting time. Finally, it may be improve the patients' and supporters' satisfaction. Therefore, this study provides basic data to enhance emergency medical services and leads to a future study to implement and extend specialized nursing systems in emergency departments.
Data Collection ; Education ; Emergencies* ; Emergency Medical Services ; Emergency Nursing ; Emergency Service, Hospital* ; Humans ; Korea ; Nursing ; Nursing, Supervisory ; Seoul ; Triage*

No abstract available.
Animals ; Dermatitis, Contact* ; Guinea Pigs* ; Guinea* ; Spleen*

We report herein a case of polymorphic pemphigoid in a 65-year-old woman, who had one-year history of generlized polymorphic eruption with intensely pruritic excoriated vesicobiullous lesions and residual pigmentation. Face and oral mucosa were spared. The skin biopsy specimen showed a subepidermal blister containing many eosinophils. Linear deposition of 1gG and C3 along the basement membrane was noticed on direct irnmunofluorescerice. Polyclonal garnmopathy with a tendency of beta-gamma bridging and increased IgG, IgA and kappachain, was frund on serum protein electrophoresis and immunoelectrophoresis. Skin lesions were well coritrolled by a combined therapy of prednisolone(20 mg/d), dapsone(100 mg/d) and cyclophosphamide(100 mg/d) for 4 months. Direct immunofluorescence performed 11 rnonths after the cnmpletion of the therapy was negative.
Aged ; Basement Membrane ; Biopsy ; Blister ; Electrophoresis ; Eosinophils ; Female ; Fluorescent Antibody Technique, Direct ; Humans ; Immunoelectrophoresis ; Immunoglobulin A ; Immunoglobulin G ; Mouth Mucosa ; Pemphigoid, Bullous* ; Pigmentation ; Skin

We experienced a case of granulation tissue occuring in lateral sulci of the right thumb, index, middle and left thumb, middle finger nails in 71-year-old psoriatic male patient taking 5pmg daily(0.6mg/kg/day) during 4th week of etretinate therapy. The excision of the granulation lesion and partial nail ablation was performed and his doses was lowered to 25mg daily (0. 3mg/kg/day). The condition were resolved with no recurrence 4 weeks later after the operation.
Acitretin* ; Aged ; Etretinate* ; Fingers ; Granulation Tissue* ; Humans ; Male ; Nails ; Recurrence ; Thumb

The patient, 23 year old female, with the Zosteriform Porokeratosis on right side of trunk and extrimity and a superimposed Disseminated Superficial Actinic Porokeratosis on face, was treated at Dept. of Dermatology, Catholic Medical College. The lesions appeared at the age of 7. Her mother had similar lesions on the face and extrimities. 3% 5-Fluorouracil in Vanishing cream base was applied topically under occlusive dressing for 40 days, and the dressing was changed every 24 hours. On seventh day erythema and papular lesion appeared, and oral administration of steroid and intermittent topical betamethasone dressing was enable to continued the occlusive dressing. One year after the treatment the lesion did not recurred and shallow atropic scar were left with normal skin color.
Administration, Oral ; Bandages ; Betamethasone ; Cicatrix ; Dermatology ; Erythema ; Female ; Fluorouracil* ; Humans ; Mothers ; Occlusive Dressings ; Porokeratosis* ; Skin ; Young Adult

No abstract available.
Dermatitis, Atopic*

Two cases of hyperlipoproteinemia is reported, Hyperlipoproteinemia is characterized by various kinds of cutaneous xanthomatosis associated with or without arteriosclerotic changes due to increasing lipoprotein fraction of the serum. Case I . 37-year old housewife had multiple, pea to nut sized, various shaped, cutaneous and subcutaneous nodular masses has been developed last 3 years. Some of her family member have similar symptoms. Serum cholesterol level was 790 mg% and serum triglyceride level was 270 mg% after 14 hour fasting. Case II. 52-year old housewife was suffered from pea sized, multiple, subcutaneous nodular and cutaneous eruptions last 2 years. There was no family histories. Serum cholesterol level was 895 mg% and serum triglyceride level was 350 mg% after 14 hour fasting. Typical Touton giant cells were found in biopsy specimens taken from cutaneous lesons. ECG, X-ray, glucose toleranc test and other laboratory examinations showed within normal limits. Tne agarose electrophoresis pattern of serum lipoprotein fractions are very similiar with that of hyperlipoproteinemia type II. These two patients were treated with nicotinic and 1. 0 gm and clofibrate 2.0 gm daily by mouth and restricted animal fatty foods. Total serum cholesterol level was markedly decreasea 2 months after treatment in case I.
Adult ; Animals ; Biopsy ; Cholesterol ; Clofibrate ; Electrocardiography ; Electrophoresis ; Fasting ; Giant Cells ; Glucose ; Humans ; Hyperlipoproteinemia Type II ; Hyperlipoproteinemias ; Lipoproteins ; Middle Aged ; Mouth ; Nuts ; Peas ; Sepharose ; Triglycerides ; Xanthomatosis