1.The Transmittance of UVA and UVB on Human Epidermis.
Yoo Won CHOI ; Hyung Chul KANG
Korean Journal of Dermatology 1997;35(3):485-490
BACKGROUND: Ultraviolet light induces sunburn, ageing of the skin, pigmentation and even promotes skin cancers. As there has been a recent decrease in the ozone layer surrounding the earth, increasing attention has been given to the effects of ultraviolet light on the skin. Through human epidermis, ultraviolet light is reflected, scattered, absorbed or transmitted. In caucacians, the rate of transmitted ultraviolet light A from the epidermis to the dermis is 50% and the rate of transmitted ultraviolet light B is below 10%. OBJECTIVE: The purpose of this study was to evaluate the transmittance of UVA and UVB on Korean normal epidermis. METHODS: Pure epidermis was obtained from normal human epidermis by suction of blisters in 12 patients with vitiligo. All specimens were irradiated respectively with UVA and UVB and the amount of transmitted energy was measured. RESULTS: 1. The transmittance of UVA energy density by normal epidermis was 47.7+11.2% of irradiated UVA energy. 2. The transmittance of UVB energy density by normal epidermis was 32.4+3.4% of irradiated UVB energy. CONCLUSION: UVA energy transmission through normal epidermis of Korean is less than those of Caucacians but UVB energy transmission through nor mal epidermis of Korean is more than those of Caucacians. It is suggested that this could be an important basic data to study for photoaging and photoprotection in Korean population.
Blister
;
Dermis
;
Epidermis*
;
Humans*
;
Pigmentation
;
Skin
;
Skin Neoplasms
;
Stratospheric Ozone
;
Suction
;
Sunburn
;
Ultraviolet Rays
;
Vitiligo
2.A Case of Connective Tissue Nevi: Elastocollagenoma compared with Elastofibroma.
Seung Min LEE ; Won Hyung KANG ; Seung Hun LEE
Annals of Dermatology 1994;6(2):230-235
No abstract available.
Connective Tissue*
;
Nevus*
3.Excretion of Trace Element into Thermal Sweat.
Won Hyung KANG ; Sung Nack LEE ; Yong CHUNG
Korean Journal of Dermatology 1988;26(1):17-21
Using atomic absorption spectrometry Pb, Cd, Cu, Zn and Fe were measured in sweat and Pb, Cd, Cu and Zn, in blood. The subjects were 22 healthy males, aged between 23-44. Sweating was induced with an environmental room (1 hour at 46C dry bulb and 36C wet bulb). Sweat samples were obtained from the left arm by the armbag technique. The sweat volume was 23.3+7.3ml(n= 22). The concentrations, in ug/ml, of trace elements in sweat were : lead, 0.18+0.17(n=22); cadmium, 0.006+0.006(n=22); copper, 0.37+0.66(n=10); zinc, 0.63+0.5(n=10); and iron, 0.22+0.12(n=10). The concentrations, in ug/ml, of trace elements in blood were : lead, 0.28+0.15(n=20); cadmium, 0.005+0.007 (n=20); copper,0.69+0.22(n=20); and zinc,5.61+0.86(n=20). These results clearly showed the significance of sweating as a route of excretion of trace element.
Absorption
;
Arm
;
Cadmium
;
Copper
;
Humans
;
Iron
;
Male
;
Spectrum Analysis
;
Sweat*
;
Sweating
;
Trace Elements
;
Zinc
4.A mathematical approach to the mode of transmission of clonorchiasis in the inhabitants of Nak-dong and Han River basin.
Ki Won SONG ; Shin Yong KANG ; Soon Hyung LEE
The Korean Journal of Parasitology 1979;17(2):114-120
To understand the mode of transmission in clonorchiasis, a survey was made in Kim-hae Goon, South Kyong-sang Do (=Province). The mathematical analysis of the age prevalence was done on the egg positive rates. And another analysis for the comparison was also made to the cited data from two areas, North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do. Some catalytic models of H. Muench (1959) were applied to the observed age prevalence. Because the both parameters, such as force of infection(a) and loss of positivity(b) were considered to be constant for a long period in the surveyed area, the two stage catalytic model by Muench was chosen to the analysis. In the surveyed area, Kim-hae Goon where the egg positive rates were 56.2 percent and 61.2 percent (by Kim, 1974), the constant values of 'a' were found to be 0.051 and 0.089 respectively. In other words, the force of infection was 51, 89 per 1,000 susceptibles. The values of 'b' were found to be 0.006 and 0.005. This means that the rates of disappearance from egg positive cases to negative were 6 and 5 per annum per l,000 positive cases in above area. Therefore, the two catalytic curves were expressed by the following equations, y = 1.133 {e(-0.006t) - e(-0.051t)} and y = 1.047 {e(-0.005t) - e(-0.089t)} respectively. In the cases of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do where the egg positive rates of clonorchis shown as 27.7 percent and 15.2 percent by Shin (1964) and Kim (l974), the curves were expressed by y = 1.769 {e(-0.010t) - e(-0.034t)} and y = 2.857 {e(-0.020t) - e(-0.027t)} respectively. From the above mathematical analyses by age prevalence in clonorchiasis, it was considered that the mode of transmission of clonorchiasis in the surveyed area, Kim-hae Goon presented more rapid pattern than those of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do.
parasitology-helminth-trematoda
;
clonorchiasis-Clnorchis sinensis
;
epidemiology
;
transmission
5.Autologous Epidermal Graft Using Suction Blister in Leg Ulcers.
Mi Ae LEE ; Yoo Won CHOI ; Hyung Chul KANG
Annals of Dermatology 1996;8(3):227-231
Regardless of the any cause leg ulcers are painful and inconvenient to patients and present clinical and economic problems due to their chronicity. Conventional skin grafts, cultured allogenic epidermis, and cultured autologous epidermis have been used for the treatment of leg ulcers. In a twenty-year-old woman with leg ulcers, autologous pure epidermal sheets were obtained from the lower chest by means of suction blisters and grafted to the leg ulcers. All lesions were healed completely in 20 days after grafting. The donor sites showed slight postinflammatory hyperpigmentations without scars. The autologous epidermal graft using suction blisters appears to be a useful method for the treatment of leg ulcers, with no immunologic rejection, no need for cultivation and anesthesia, no desiccation, and no scars on the donor sites.
Anesthesia
;
Blister*
;
Cicatrix
;
Desiccation
;
Epidermis
;
Female
;
Humans
;
Leg Ulcer*
;
Leg*
;
Methods
;
Skin
;
Suction*
;
Thorax
;
Tissue Donors
;
Transplants*
6.Chemical burn due to weed killer, Gramoxone@(paraquat dichloride).
Son Won BYEON ; Hye Goo JI ; Seung Kyung HANN ; Won Hyung KANG ; Jinhyong WON
Korean Journal of Dermatology 1991;29(2):218-221
A 62-year-old farmer was admitted to our department because of second degree chemical burns of both buttocks ten days following accidental contact with Gramoxone, a weed killer. He was treated with oral antibiotics and cold compresses and discharged after the burned area were reepithelialized. Laboratory findings were within normal limits for three weeks. Although lung fibrosis, hepatic and renal failure can be caused by repeated absorption of paraquat (Gramoxone) through injuried skin, systemic absorption through normal skin has not been reported. During the four month follow up period there were no systemic problems nor recurrence of skin lesions. We report herein a case of chemical burns induced by Gramoxone, which is probably an occupational dermatosis of farmers handling weed killers.
Absorption
;
Anti-Bacterial Agents
;
Burns
;
Burns, Chemical*
;
Buttocks
;
Fibrosis
;
Follow-Up Studies
;
Humans
;
Lung
;
Middle Aged
;
Paraquat
;
Recurrence
;
Renal Insufficiency
;
Skin
;
Skin Diseases
7.A Case of Proliferating Trichilemmal Tumor.
Soo Il CHUN ; Hyung Joo KIM ; Won Hyoung KANG ; Tai Seung KIM
Korean Journal of Dermatology 1985;23(4):539-542
Proliferating trichilernmal tumor is a rare benign solitary tumor that may be histopathologically misinterpreted as squarnous cell carcinoma. It affects frequently the scalp of elderly women. We present herein a case of proliferating trichilemmal tumor in an 87-year-old male who had had a slowly growing tumor on the scalp for 30 years.
Aged
;
Aged, 80 and over
;
Female
;
Humans
;
Male
;
Scalp
8.Anatomical Study on the Location of the Mental Foramen in Adult Korean Mandibles.
Kyung Won YOON ; Kang Ryune KIM ; Jae Hyung WOO ; Jin Jeong KIM ; Jae Bong KIM
Korean Journal of Physical Anthropology 1989;2(1):11-17
We examined the anatomical position of the mental foramina in mandibles foramen normal adult Koreans. 1. The percentages obtained from the study of the relationships between the mental foramen and the lower teeth showed that the most common location was type lv in which the mental foramen lay at the apex of the second promolar. The foramen between thr apices of ice two premolars (type lll) and the foramen between the second premolar and the first molar (type v) occured often and less often rspectively and find no foramen mesial to the first premolar or at the apex of the first premolar and posterior of the first molar (type l, ll, vl). 2. The study of relationship of the mental foramen to the bo of the mandible revealed that mental foramen was situated closer to the lowed border of the mandibular body. The distance ratio between the mental foramen and the alveolar crest to that between the mental foramen and the lower border was approximately 1.2 : 1. The height of the mandibular body was 31.09±2.80mm on the left side and 30.97±2.48mm on the right. 3. The distance from the mandibular symphysis to the anterior border of the mental foramen measured 29.52±2.01mm on the left, 30.82±2.04mm on the right side, and from the mandibular symphysis to the posterior border of the mandibular ramus was 104.20±4.74mm on the left, 105.44±4.49mm on the right side. It indicates that the mental foramen lies approximately at one-fourth of the distance from the mandibular symphysis to 2017-04-19 the posterior border of the ramus. 4. The distance from the superior border of the mental foramen to the bottom of the lower second premolar socket was found to be positive. It was 5.46±3.09mm on the left, 5.73±3.03mm on the right side. This indicates that the bottom of the lower second premolar socket is slightly higher than the superior border of the mental foramen.
Adult*
;
Bicuspid
;
Humans
;
Ice
;
Mandible*
;
Molar
;
Tooth
9.A Case of Ectopic Hydatidiform Mole in the Uterine Cornua.
Jeong Oh KANG ; In Young YOO ; Sang Yong KIM ; Jeung Hyung LEE ; Chae Won LEE
Korean Journal of Obstetrics and Gynecology 1999;42(2):392-395
Ectopic pregnancy refers to gestation in which the fertilized ovum implants on any other tissure than tbe mucus membrane lining the uterine cavity. Cornual (intertitial) pegnancy is a relatively uncommon but potentially catastrophic form of ectopic pregnancy, defined as implantation in the intramural portion of a fallopian tube. A hydatidiform mole usually occupies the uterine cavity but it's occurrence in the uterine tube is extremely rare. Only a few cases of primary hydatidifm mole of the tube have been reported. We experienced a case of ectopic hydatidiform mole in the uterine cornua and so present it with brief review of literatures.
Fallopian Tubes
;
Female
;
Hydatidiform Mole*
;
Membranes
;
Mucus
;
Pregnancy
;
Pregnancy, Ectopic
;
Zygote
10.Effect of Cimetidine on Contact Sensitivity Reaction in Guinea Pigs.
Bo Hyung KIM ; Tae Yoon KIM ; Kang Woo LEE ; Won HOUH
Korean Journal of Dermatology 1982;20(5):641-646
Cimetidine, an H-histamine receptor antagonist, has been advocated to have enhancing effect on delayed type hypersensitivity. However, some recent reports have caused controversial opinion regarding the effect of cimetidine on delayed type hypersensitivity assessed in vivo. In this study the effect of cimetidine at the various periods of contact sersitivity reaction (CSR) to DNCB was assessed in guinea pigs. Three groups of five guinea pigs were sensitized with DNCB in the nuchal region and challenged with DNCB in the back on 16th day after sensitization, Cimetidine, 300mg/3ml/kg, was injected intraperitoneally once a day for the duration of different periods. For the first group, cimetidine was injected during the first 10 days after sensitization to assess its effect on the preparative and recognition phase of the induction period of CSR, For the second group, cimetidine was injected from the 6th to the 16th day to evaluate the enhancing effect of cimetidine on CSR at the period when suppressor T-cells were considered to be active. For the third group, cimetidine was injected for the last 3 days before elicitation test to assess the effect of short term treatment of cimetidine on the established CSR to DNCB. For the elicitation, two different consentrations of DNCB were applied on the three sites along both sides of the spine in the back. Total means of the degree of CSR elicited by DNCB were significanly ircreased by cimetidine in the second and third groups (p<0.05). These enhancing effects of cimetidine on CSR were more prominent at the uppermost back than other sites, eliclted by 0.05% DNCB rather than 0.01% DNCB.
Animals
;
Cimetidine*
;
Dermatitis, Contact*
;
Dinitrochlorobenzene
;
Guinea Pigs*
;
Guinea*
;
Hypersensitivity
;
Spine
;
T-Lymphocytes