1.Comparison of the Epidemiology and Clinical Characteristics of Primary Hepatocellular Carcinoma Between HBsAg and Anti-HCV Positive Group.
Choo Yon CHO ; Jin Won KIM ; Seong Ho HONG ; Shin Bae LEE ; Han Mu LEE
Journal of the Korean Academy of Family Medicine 1997;18(1):53-64
BACKGROUND: Primary hepatocellular carcinoma(HCC) is the second cause of cancer death in our country. Hepatitis B virus(HBV) and hepatitis C virus(HCV) are important risk factors for hepatocellular carcinoma. The mechanism of HCC development and the epidemiology in HCV infected individuals are still unclear. In this study, we investigated the epidemiolgical and clinical features of HCC in relation to viral infection. METHODS: We reviewed the medical records of 160 HCC patients retrspectively who had been admitted to one University Hospital located in Seoul between January 1991 and December 1995. Among these patients, 113 patients were positive for HBsAg(B group), 24 for anti-HCV(C group). We compared epidemiological and clinical data between B group and C guoup. RESULTS: Anti-HCV positivity was significantly higher in HBsAg negative patients than in HBsAg positive patients(53.3:1.7%, p<0.01). The mean age of patients in B group was significantly lower than that in C group(52:62yr, p<0.01). In C group, the proportion of Child-Pugh class B and C was significantly larger than that of B group(35.4: 75.0%, p<0.01). In C group, the proportion of transfusion history was significantly larger than that in B group(4.4: 16.7%, p<0.05), and the proportion of drug abuse hestory was significantly larger than that in B group (31.0:62.5%, p<0.01). In C group, the albumin, cholesterol, Gamma-glutamyl transferase leves were significantly lower than those in B group. In B group, the proportion of metastasis was significantly larger than that in C group(31.9:4.2%, p<0.01). Alpha fetoprotein levels greater than 400ng/ml are much more prevalent in group B significantly(67:39.1%, p<0.05). No significant differences in cumulative survival rate(1yr, 2yr) and median survival time were observed between the two groups. CONCLUSIONS: We ascertain that the HBV and HCV are inportant factors in HCC. In epidemiology and clinical features of HCC, there were some difference between the HBsAg and anti HCV positive group. Therefore, on primary health care settings, it is necessary to test for hepatitis C as well as hepatitis B in order to prevent and manage HCC and chronic liver desease.
alpha-Fetoproteins
;
Carcinoma, Hepatocellular*
;
Cholesterol
;
Epidemiology*
;
Hepatitis B
;
Hepatitis B Surface Antigens*
;
Hepatitis C
;
Humans
;
Liver
;
Medical Records
;
Neoplasm Metastasis
;
Primary Health Care
;
Risk Factors
;
Seoul
;
Substance-Related Disorders
;
Transferases
2.A clinical review of the patients with upper gastrointestinal bleed- ing entered to emergency room and factors influencing the outcome.
Sun Jin KIM ; Pyeong Rang CHOO ; Won Sook GYE ; Ho Cheol SHIN ; Eun Sook PARK
Journal of the Korean Academy of Family Medicine 1991;12(2):20-27
No abstract available.
Emergencies*
;
Emergency Service, Hospital*
;
Humans
3.Primary Ovarian Leiomyosarcoma: A case report.
Won Sang PARK ; Seong Beom LEE ; Jung Yong LEE ; Sang Ho KIM ; Choo Soung KIM
Korean Journal of Pathology 1996;30(6):548-550
Primary leiomyosarcoma is a rare tumor of the ovary. We experienced a case of primary ovarian leiomyosarcoma in a 68 year old woman. Microscopically, the tumor was characterized by interlacing bundles of plump spindle cells that showed immunoreactivity for alpha-smooth muscle actin, pleomorphic multinucleated giant cells and an increased mitotic rate. Ultrastructural features included abundant smooth muscle type filaments and irregular bodies. Consequently, this case has led us to propose ultrastructural and immunohistochemical criteria for primary ovarian leiomyosarcoma.
Female
;
Humans
4.The survival rate and causes of death in patients with chronic renal failure on hemodialysis.
Won Suk CHOO ; Ki Woun KIM ; Dong Ho YANG ; Sae Yong HONG
Korean Journal of Nephrology 1992;11(1):56-61
No abstract available.
Cause of Death*
;
Humans
;
Kidney Failure, Chronic*
;
Renal Dialysis*
;
Survival Rate*
5.Clinical analysis of cesarean section.
Chul Won JHANG ; Kyong Ran JU ; Seong Ho CHOO ; Bong Soo OH
Korean Journal of Obstetrics and Gynecology 1992;35(6):827-834
No abstract available.
Cesarean Section*
;
Female
;
Pregnancy
7.Clinical study of ectopic pregnancy.
Sung Ho CHOO ; Sang Hoon LEE ; Chul Won JHANG ; Ok KO ; Kyung Ran JOO ; Joo Wook KIM
Korean Journal of Obstetrics and Gynecology 1993;36(7):1452-1458
No abstract available.
Female
;
Pregnancy
;
Pregnancy, Ectopic*
8.A study on the domestice accidents in Seoul.
Won Sook KYE ; Sun Jin KIM ; Pheung Rang CHOO ; Hyun Ju BOO ; Ho Cheol SHIN ; Eun Sook PARK
Journal of the Korean Academy of Family Medicine 1991;12(10):40-50
No abstract available.
Seoul*
9.Expression of c-fms in each stage of chronic myelogenous leukemia.
Chong Won PARK ; Il Ho YANG ; Chong Wook LEE ; Chi Wha HAN ; Woo Sung MIN ; Chun Choo KIM ; Won Il KIM ; Dong Jip KIM
Journal of the Korean Cancer Association 1991;23(3):529-535
No abstract available.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*
10.A case of staphylococcal myocaridtis with complete atrioventricular block.
Ho Chul SONG ; Kee Bae SEUNG ; Jong Soon RAH ; Kyo Yung CHOO ; Won Yung LEE ; Dong Hun KANG ; Kyoo Bo CHOI ; Moon Won KANG
Korean Journal of Infectious Diseases 1993;25(4):383-386
No abstract available.
Atrioventricular Block*