1.A Case of Subungual Exostosis.
Korean Journal of Dermatology 1983;21(4):433-437
Subungual exostosis is not a true exostosis, but an outgrowth of normal bone tissue, which is traumatic disputedly in causative factor, involving mainly the great toe. We experienced a case which a hard nodule, l. 0 crn in diameter, of the great toe of the left foot, developed in a 24-year-old woman. Her lesion had begun about 6 months earlier, accompanying the dull pain or tenderness when wearing the shoes or walking. Confirmatory diagnosis was biopsy with biopsy and X-ray findings after nail avulsion. We performed the lesion with curettage on therapeutic trial without effect.
Biopsy
;
Bone and Bones
;
Curettage
;
Diagnosis
;
Exostoses*
;
Female
;
Foot
;
Humans
;
Shoes
;
Toes
;
Walking
;
Young Adult
2.An Immunohistochemical Study of Alpha-1-antichymotrypsin and Lysozyme in the Hofbauer Cells of Human Placentas.
Ho Won HWANG ; Ho Jong CHUN ; Chae Hong SUH
Korean Journal of Pathology 1988;22(1):63-69
The present study has shown that immunohistochemical staining of the human placentas (5 first trimester and 20 full term placentas) for confirmation of the monocytic linease of its macrophage function. We used two macrophage associated glycoprotein; alpha-1-antichymotrypsin (A1Ac) and lysozyme (LSZ). The results from presence or absence of A1Ac & LSZ by immunohistochemical methods can be helpful to deceide the degree of differentiation of macrophage. In al the placentas examined a strong cytoplasmic reaction for A1Ac was seen in the Hofbauer cells, and the same cells of serial sections didn't stain for LSZ. The strong cytoplasmic reaction for A1Ac supports that Hofbauer cells are macrophage, but they didn't stain for LSZ, a bactericidal enzyme, we propose that these cells are not fully differentiated macrophage. The lack of LSZ may have some relevance to the pathogenesis of certain placental infections.
Humans
3.A Study of Vascular Changes in the Lymph Nodes.
Hye Suk SONG ; Ho Won HWANG ; Chae Hong SUH
Korean Journal of Pathology 1985;19(2):179-186
A retrospective morphological study was conducted on 1677 lymph nodes which were removed surgically under the diagnosis of gastric carcinoma, breast carcinoma, colonic carcinoma, chronic gastric ulcer, and superficial lymph nodes nuder the diagnosis of reactive follicular hyperplasia at Chosun University Hospital during a period of 5 years from 1980 to 1984. The hematoxylin and eosin stained sections were examined to evaluate for any vascular changes. In selected cases further levels were prepared from the paraffin blocks for Gomori's reticulin stain. The vascular abnormalities were divided into 3 groups, such as hemangiomatoid, pan-nodal vasodilatation and miscellaneous types. The miscellaneous type included the proliferation of smooth muscle which encircled numerous small hilar arteries and veins. The results obtained were as follows: 1) The hemangiomatoid lesions were localized lesions which appeared to be associated with local malignancy, but infrequent in incidence. 2) A more frequent vascular abnormality was pan-nodal vasodilatation, which tend to affect many nodes in a single group and is relatively associated with chronic gastric ulcer. 3) Miscellaneous lesion was nonspecific and appeared both local malignancy and chronic inflammation. 4) All three vascular reactions were somewhat more frequent in female than male.
Female
;
Humans
;
Incidence
4.A Case of Cutaneous Hemorrhagic Bullous Eruptions in Lymphoma of the Small Intestine.
You Ho CHAE ; Byung Jin LEE ; Sang Won KIM
Korean Journal of Dermatology 1985;23(1):125-130
Authors experienced a 59-year-old male patient with the lymphoma of the small iritestine which involved the adjoining mesenteric lymph nodes, the parietaI pleura, and the skin. The skin lesions, simulating necrotizing angiitis, were deep purple colored, asymptomatic, tense, hemorrhagic bullae with soft consistency on the both thighs and left infraorbital area. He had extranodal type, and diffuse, poorly differentiated lymphocytic lymphoma by the Rappaport classification, and stage IV by the Ann Arbor staging classification. After about 50 days of clinical manifestations, he was died mainly due to massive intestinal bleeding.
Classification
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Hemorrhage
;
Humans
;
Intestine, Small*
;
Leukemia, Lymphocytic, Chronic, B-Cell
;
Lymph Nodes
;
Lymphoma*
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Male
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Middle Aged
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Pleura
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Skin
;
Thigh
;
Transcutaneous Electric Nerve Stimulation
;
Vasculitis
5.Syphilis Prevalence in Teagu Hope Village.
You Ho CHAE ; Sung Hwa KIM ; Sang Won KIM
Korean Journal of Dermatology 1986;24(2):249-253
Serologic tests for syphilis, including VDRL and TPHA tests, and Physical examination were carried out on 1, 605 subjects who lived in Taegu Hope Village, a social welfare center, from April, 198R to May, 1985. We prepared this study comparing with previous reports for healthy individuals and prostitutes. The results were as follows, The reactive rate of VDRL. qualitative test was 11. 6% in total, 10. 3%, in men and l3. 5%. in women. The reactive rates of VDRL. qualitative tests were highest in 7 th decade as 28, 7% and followed by 6 th decade as 16. 7% the decacile as 16. 0% 8 th decade as 14,3% 4th decade as 8. 8% and 3rd decade as 5. 9%, 3 In ]Hg sero-positive subjects, VDRL quantitative tests were done, and 35. 5% were reacted with 1: 8 or high and 29. 0% had one or more syphilitic lesions. 4 In 54 subjects who had one or more syphilitic lesions, 19 had chancres, 17 had alopecia syphilitica, 7 had rnaculopapular syphilid, 7 had condylomata lata. 3 had papular syphilid, and 1 had maculopapular syphilid and alopecia syphilitica. The biological false positive rate was 10. 1,4 in 138 VDRL reactive subjects, using 1;he TPHA test standard.
Alopecia
;
Chancre
;
Daegu
;
Female
;
Hope*
;
Humans
;
Male
;
Physical Examination
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Prevalence*
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Serologic Tests
;
Sex Workers
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Social Welfare
;
Syphilis*
;
Syphilis, Cutaneous
6.Two Cases of Keratosis Palmaris et Plantaris.
You Ho CHAE ; Sung Hwa KIM ; Sang Won KIM
Korean Journal of Dermatology 1985;23(2):229-234
We described here-in a 36-year-old male patient (case 1) with a severe form of keratosis palmaris et plantaris(Thost-Unna type) which was diffuse hyperkeratosis with hyperhidrosis on the entire surface of the palms and soles. His son, 8-year- old boy, showed symmetrical distribution of hyperkeratotic patches on the inner sides of both great toes(case 2). Therefore, it was suggested this genodermatosis occured in two generations of a family. The biopsy taken from the right palm of case 1 showed features of epidermal hyperplasia with hyperkeratosis, hypergranulosis and acanthosis. We tried the oral Vit. A therapy(50,000 unit, daily) in case 2. The hyperkeratotic lesions became slightly improved in 4 months after therapy.
Adult
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Biopsy
;
Family Characteristics
;
Humans
;
Hyperhidrosis
;
Hyperplasia
;
Keratoderma, Palmoplantar*
;
Keratosis*
;
Male
7.11 Cases of Aspergillosis.
Ho Won HWANG ; Jang Shin SOHN ; Chae Hong SUH
Korean Journal of Pathology 1985;19(3):325-331
Genus of aspergilli are ubiquitous saprophytic molds in nature, which are recognized about 700 species, at least eight are pathologic for human. Pulmonary aspergillosis is rare disease, most frequent presenting as secondary invasion, and aspergillosis of the nasal cavity is the most common sites of the extrapulmonary aspergillosis. Predisposing factors for pulmonary aspergillosis are chronic lung disease, tuberculosis, antibiotics, cytotoxins and neoplasia, hematologic disorders, and histoplasmosis etc. Authors have experienced 10 cases of pulmonary aspergillosis and a case of aspergillosis of nasal cavity in Dept. of Pathol. Chosun univ. hospital and christian hospital from Feb. 1981 to July 1984. Patient of pulmonary aspergillosis are received surgical resection and survived well without complications.
Humans
;
Cytotoxins
8.Mid-term Clinical & Angiographic Outcomes of Primary Stenting in Acute Myocardial Infarction.
Jei Keon CHAE ; Koang Ho CHOI ; Sung Ki MOON ; Won Ho KIM ; Jae Ki KO
Korean Circulation Journal 1999;29(1):28-35
BACKGROUND AND OBJECTIVES: The goal of this study was to examine the safety and feasibility of a primary (direct) stenting in acute myocardial infarction (AMI). In the treatment of AMI, Percutaneous transluminal coronary angioplasty (PTCA) has documented superior reperfusion rate and improved clinical outcomes than thrombolytic therapy. However, there are several limitations of PTCA, such as recurrent ischemia in 10 to 15%, reinfarction in 3 to 5% and restenosis in 30 to 50% of patients. There are several reports that, compared with PTCA, the implantation of coronary stent has been shown to reduce angiographic restenosis and improve late clinical outcomes. But in general, stenting has been contraindicated in thrombus containing lesion due to the risk of subacute thrombosis. With advance in technique and the recognition of the importance of adequate platelet inhibition, the incidence of subacute thrombosis has fallen in patients with acute coronary syndrome and thrombus laden lesion. Methods and Results: In our study, primary stenting was performed in 42 patients of AMI. There are 6 cases (22.5%) target lesion restenosis during the follow up coronary angiography (150+/-86day) and no in-hospital death. Three cases (7.1%) of them require revascularization including two re-PCTA and a coronary artery bypass graft for the recurrent ischemic symptoms. There were no reinfarction and death after discharge. Six-months event free survival reate was 85.7%. CONCLUSION: Primary stenting is safe and feasible in the majority of patients with AMI and results in excellent mid-term outcomes compared with PTCA.
Acute Coronary Syndrome
;
Angioplasty, Balloon, Coronary
;
Blood Platelets
;
Coronary Angiography
;
Coronary Artery Bypass
;
Disease-Free Survival
;
Follow-Up Studies
;
Humans
;
Incidence
;
Ischemia
;
Myocardial Infarction*
;
Reperfusion
;
Stents*
;
Thrombolytic Therapy
;
Thrombosis
;
Transplants
9.A Case of Pheochromocytoma Presented with Acute Myocardial Infarction.
Hyun Sun JEON ; Sung Ki MOON ; Jei Keon CHAE ; Won Ho KIM ; Jae Ki KO
Korean Circulation Journal 1999;29(3):306-310
A 36-year-old woman was presented with extensive anterior wall myocardial infarction. We tried to perform direct coronary angiography for the purpose of primary stenting. However, coronary angiogram revealed normal coronary arteries without intracoronary thrombi. We continued further evaluations to find out the cause of normal coronary myocardial infarction. The findings of severe hypertensive retinopathy and concentric left ventricular hypertrophy suggested that she had secondary hypertension. The detailed history, laboratory and radiological findings revealed the pheochromocytoma. The tumor was successfully removed by operation.
Adult
;
Anterior Wall Myocardial Infarction
;
Coronary Angiography
;
Coronary Vessels
;
Female
;
Humans
;
Hypertension
;
Hypertensive Retinopathy
;
Hypertrophy, Left Ventricular
;
Myocardial Infarction*
;
Pheochromocytoma*
;
Stents
10.Early and Mid-term Results of Coronary Stenting in the Diabetic Patient.
Hyun Sun JEON ; Jei Keon CHAE ; Sung Ki MOON ; Won Ho KIM ; Jae Ki KO
Korean Circulation Journal 1999;29(3):292-297
BACKGROUNG AND OBJECTIVES: Diabetes mellitus is a significant risk factor for adverse outcome after PTCA, which is associated with an increased late mortality and target lesion revascularization (TLR) rates. The beneficial role of coronary stenting on the clinical and angiographic outcomes of diabetic patients is not clearly defined. The aim of this study was to evaluate the early and mid-term outcomes in diabetic patients undergoing elective stenting of native coronary lesions compared with those in non-diabetic patients. MATERIALS AND METHODS: Between July 1997 and June 1998, coronary stenting was performed on 46 lesions in 38 diabetic patients and 126 lesions in 117 non-diabetic patients. Follow-up angiography at mean day of 189+/-45 was performed in 58.7% (91 patients) and analysed by quantitative coronary angiography (QCA). RESULTS: There was a higher incidence of multi-vessel disease in diabetic patients than non-diabetic patients but not statistically significant (71.1% vs 51.3%, p=0.106). There were no differences in major procedural complications and in-hospital events (myocardial infarction, angina and death) in diabetics and non-diabetics. During the follow-up, the incidence of target lesion revascularizton (TLR) and cardiac event free survival did not differ between two groups. CONCLUSION: Coronary stenting in diabetics resulted in a low rate of immediate procedural com-plications and early major adverse cardiac event (MACE), similar to non-diabetics. There were no differences in the mid-term clinical and angiographic outcomes in diabetics and non-diabetics.
Angiography
;
Coronary Angiography
;
Diabetes Mellitus
;
Disease-Free Survival
;
Follow-Up Studies
;
Humans
;
Incidence
;
Infarction
;
Mortality
;
Risk Factors
;
Stents*