1.An Epidemiological Study on the Accident resulting from Leakage of Chloride.
Joon Yun KIM ; Won Gae CHO ; Jong Hwan PARK ; Chong Kyun LEE ; Yong Chun KIM ; Don Kyoun KIM
Korean Journal of Preventive Medicine 1972;5(1):49-56
During the Period from 22th to November 26th , 1971, An Epidemiological Survey was performed on the Accident which was occurred by Leakage of Chloride Gases in A Chimical Industry, one of Wul San Industrial Areas. The obtained results were as follows ; 1. The largest damage was observed at Yeo Cheon Dong, 5.38 Km2 in Area and 8,192 in the Residents. 2. By the age distribution of Yeo Cheon Dong, The largest damaged area resulting from chloride accident, the age group of between 10 and 39 was highly occupied with 55.2% of all Yeo Cheon residents. 3. The number of patient was 436 totally, 198 in male and 238 in female. 4. By the age group distribution of the patient, in case of male, the largest group was under 20 age (96) and female, between 20 and 40 age group. 5. By the educational level of the patient, No-Education group was 116 (26.6%), and primary school, middle school and high school were respectively 168 (38.5%), 68(15.6%) and 12 (2.8%). 6. By the occupational distribution of the patient, No-Occupation group was 49.7%, students and agriculture were respectively 14.4% and 8.1%. 7. By the complaints of the patient, most of all were for respiratory tract, those are coughing (56.9%), chest tightness (35.6%), sore throat (24.8%), and so forth. 8. By the injured domestic animal, the Dog was most highly injured with 46.2%.
Age Distribution
;
Agriculture
;
Animals
;
Animals, Domestic
;
Cough
;
Dogs
;
Epidemiologic Studies*
;
Female
;
Gases
;
Humans
;
Male
;
Pharyngitis
;
Respiratory System
;
Thorax
2.A Study on Health Status of Industrial Workers by Application of the Modified C.M.I..
Joon Yun KIM ; Won Gae CHO ; Chong Kyun LEE ; Yong Chun KIM ; Hea Koun PARK ; Don Kyoun KIM
Korean Journal of Preventive Medicine 1972;5(1):25-35
From May lst to November 30th, 1971, a study was conducted by authors on the health status of industrial workers through applying the modified Cornell Medical Index forwards a total of 4,565 labourers working in Busan City. The obtained results were as follows : 1. The largest number of industries and labourers was in Busanjin Gu, 9 and 2,386 (52.2%), respectively. 2. Total numbers of labourers subjected to the survey were 2,355 (51.6% in male, 2,210(48.4%) in female. 3. By age and sex distribution, the largest was seen with the age group of 25-34, 1,260 in male, otherwise with under the age group of 24, 1,994 in female labourers. 4. The highest average number of complaints by section among all age groups and industries was as follows ; In case of male labourers, textile was the highest with numbering 8.7 (35-39 age group) in the section of physical complaints, in the section of mental and total complaints, food industry was the highest with numbering 8.2 and 16.4, respectively, both under 19 age group, otherwise in case of female labourers, food industry was the highest with numbering 12.3 (physical), 10.3(mental) and 22.7 (total complaints) with all in 20-24 age group. 5. The lowest average number of complaints by section among all age groups and industries was as follows; In case of male labourers, other industry was the lowest with numbering 0.4 (55and over) in the physical, 0.3 (19and under) in the mental and 0.7 (55and over) in the section of total complaints, otherwise incase of female labourers, basic metal was the lowest in the all sections with all in 50-54 age groups.
Busan
;
Cornell Medical Index
;
Female
;
Food Industry
;
Humans
;
Male
;
Sex Distribution
;
Textiles
3.An Epidemiological Study on the Accident resulting from Leakage of Chloride.
Joon Yun KIM ; Won Gae CHO ; Jong Hwan PARK ; Chong Kyun LEE ; Yong Chun KIM ; Don Kyoun KIM
Korean Journal of Preventive Medicine 1972;5(1):49-56
During the Period from 22th to November 26th , 1971, An Epidemiological Survey was performed on the Accident which was occurred by Leakage of Chloride Gases in A Chimical Industry, one of Wul San Industrial Areas. The obtained results were as follows ; 1. The largest damage was observed at Yeo Cheon Dong, 5.38 Km2 in Area and 8,192 in the Residents. 2. By the age distribution of Yeo Cheon Dong, The largest damaged area resulting from chloride accident, the age group of between 10 and 39 was highly occupied with 55.2% of all Yeo Cheon residents. 3. The number of patient was 436 totally, 198 in male and 238 in female. 4. By the age group distribution of the patient, in case of male, the largest group was under 20 age (96) and female, between 20 and 40 age group. 5. By the educational level of the patient, No-Education group was 116 (26.6%), and primary school, middle school and high school were respectively 168 (38.5%), 68(15.6%) and 12 (2.8%). 6. By the occupational distribution of the patient, No-Occupation group was 49.7%, students and agriculture were respectively 14.4% and 8.1%. 7. By the complaints of the patient, most of all were for respiratory tract, those are coughing (56.9%), chest tightness (35.6%), sore throat (24.8%), and so forth. 8. By the injured domestic animal, the Dog was most highly injured with 46.2%.
Age Distribution
;
Agriculture
;
Animals
;
Animals, Domestic
;
Cough
;
Dogs
;
Epidemiologic Studies*
;
Female
;
Gases
;
Humans
;
Male
;
Pharyngitis
;
Respiratory System
;
Thorax
4.A Study on Health Status of Industrial Workers by Application of the Modified C.M.I..
Joon Yun KIM ; Won Gae CHO ; Chong Kyun LEE ; Yong Chun KIM ; Hea Koun PARK ; Don Kyoun KIM
Korean Journal of Preventive Medicine 1972;5(1):25-35
From May lst to November 30th, 1971, a study was conducted by authors on the health status of industrial workers through applying the modified Cornell Medical Index forwards a total of 4,565 labourers working in Busan City. The obtained results were as follows : 1. The largest number of industries and labourers was in Busanjin Gu, 9 and 2,386 (52.2%), respectively. 2. Total numbers of labourers subjected to the survey were 2,355 (51.6% in male, 2,210(48.4%) in female. 3. By age and sex distribution, the largest was seen with the age group of 25-34, 1,260 in male, otherwise with under the age group of 24, 1,994 in female labourers. 4. The highest average number of complaints by section among all age groups and industries was as follows ; In case of male labourers, textile was the highest with numbering 8.7 (35-39 age group) in the section of physical complaints, in the section of mental and total complaints, food industry was the highest with numbering 8.2 and 16.4, respectively, both under 19 age group, otherwise in case of female labourers, food industry was the highest with numbering 12.3 (physical), 10.3(mental) and 22.7 (total complaints) with all in 20-24 age group. 5. The lowest average number of complaints by section among all age groups and industries was as follows; In case of male labourers, other industry was the lowest with numbering 0.4 (55and over) in the physical, 0.3 (19and under) in the mental and 0.7 (55and over) in the section of total complaints, otherwise incase of female labourers, basic metal was the lowest in the all sections with all in 50-54 age groups.
Busan
;
Cornell Medical Index
;
Female
;
Food Industry
;
Humans
;
Male
;
Sex Distribution
;
Textiles
5.A Case of Stent Migration into Right Ventricle after Percutaneous Transluminal Angioplasty for Budd-Chiari Syndrome.
Mi Ran SIM ; Wha Sook KIM ; Won Kyung PARK ; Gae Hyuk MOON ; Eui Soo HONG ; Jeong Kee SEO ; Seong CHO ; June KWAN ; Keum Soo PARK ; Woo Hyung LEE
Korean Circulation Journal 2000;30(7):885-889
No abstract available.
Angioplasty*
;
Budd-Chiari Syndrome*
;
Heart Ventricles*
;
Stents*
6.Standard Chemotherapy with Excluding Isoniazid in a Murine Model of Tuberculosis.
Tae Sun SHIM ; Eun Gae LEE ; Chang Min CHOI ; Sang Bum HONG ; Yeon Mok OH ; Chae Man LIM ; Sang Do LEE ; Younsuck KOH ; Woo Sung KIM ; Dong Soon KIM ; Sang Nae CHO ; Won Dong KIM
Tuberculosis and Respiratory Diseases 2008;65(3):177-182
BACKGROUND: Isoniazid (INH, H) is a key drug of the standard first-line regimen for the treatment of tuberculosis (TB), yet some reports have suggested that treatment efficacy was maintained even though INH was omitted from the treatment regimen. METHODS: One hundred forty C57BL/6 mice were infected with the H37Rv strain of M. tuberculosis with using a Glas-Col aerosol generation device, and this resulted in depositing about 100 bacilli in the lung. Four weeks after infection, anti-TB treatment was initiated with varying regimens for 4-8 weeks; Group 1: no treatment (control), Group 2 (4HREZ): 4 weeks of INH, rifampicin (R), pyrazinamide (Z) and ethambutol (E), Group 3: 1HREZ/3REZ, Group 4: 4REZ, Group 5: 4HREZ/4HRE, Group 6: 1HREZ/3REZ/4RE, and Group 7: 4REZ/4RE. The lungs and spleens were harvested at several time points until 28 weeks after infection, and the colony-forming unit (CFU) counts were determined. RESULTS: The CFU counts increased steadily after infection in the control group. In the 4-week treatment groups (Group 2-4), even though the culture was negative at treatment completion, the bacilli grew again at the 12-week and 20-week time points after completion of treatment. In the 8-week treatment groups (Groups 5-7), the bacilli did not grow in the lung at 4 weeks after treatment initiation and thereafter. In the spleens of Group 7 in which INH was omitted from the treatment regimen, the culture was negative at 4-weeks after treatment initiation and thereafter. However, in Groups 5 and 6 in which INH was taken continuously or intermittently, the bacilli grew in the spleen at some time points after completion of treatment. CONCLUSION: TThe exclusion of INH from the standard first-line regimen did not affect the treatment outcome in a murine model of TB in the early stage of disease. Further studies using a murine model of chronic TB are necessary to clarify the role of INH in the standard first-line regimen for treating TB.
Animals
;
Ethambutol
;
Isoniazid
;
Lung
;
Mice
;
Pyrazinamide
;
Rifampin
;
Spleen
;
Sprains and Strains
;
Stem Cells
;
Treatment Outcome
;
Tuberculosis
7.A Multicenter Study on Effects of Nefazodone(Serzone TM) on Depression, Anxiety, Sleep, Sexual Functions, and Quality of Life in Patients with Depression.
Sung Kil MIN ; Byung Jo KANG ; In Kwa JUNG ; Maeng Je CHO ; Jin Sang YOON ; Dong Kee KIM ; Min Hee KANG ; Doh Kwan KIM ; Myung Jung KIM ; Suk Hyung KIM ; Yong Ku KIM ; Jung Ki KIM ; Min Cheol PARK ; Gae Won BANG ; Bong Ki SOHN ; Ji Yong SHIN ; Kang Seob OH ; Bo Hyun YOON ; Kyung Kyu LEE ; Sang Keun CHUNG ; Young Ki JUNG ; In Won JUNG ; Hee Yeon JUNG ; Young Moe JE ; Ik Seung CHEE ; Byung Moo CHOI ; Sun Ho HAN ; Oh Su HAN
Korean Journal of Psychopharmacology 2001;12(3):211-221
OBJECTIVE: The aim of this study is to determine effects of nefazodone on depression, anxiety, sleep and sexual function in depressive patients. SUBJECTS AND METHODS: This is an open, non-comparative, multi-center study. Antidepressant and other clinical effects of nefazodone were evaluated in 230 patients of 26 centers, aged 14 years or more, who met DSM-IV criteria to major depressive disorder or dysthymic disorder and didn't have other psychiatric disorders and were physically healthy. The clinical efficacy was assessed at week 1, 2, 4 and 8 using Clinical Global Improvement (CGI), Hamilton Depression Scale (HAM-D), Beck Depression Inventory (BDI), State and Trait Anxiety Inventory-State Anxiety (STAI-SA). Other clinical effects were assessed with Weekly Sleep Questionnaire, Sexual Functioning Questionnaire and GHQ-QOL-12, a scale for quality of life. Adverse drug reactions were checked with a questionnaire. Post-treatment effects of drug were compared with pre-treatment baseline condition. RESULTS: The response rates by Clincal Grobal Improvement and HAM-D after 8 weeks treatment were 62.4% and 75.2% respectively. Comparing to baseline, nefazodone was proved to have significantly higher antidepressant and antianxiety effects in depressive patients and it improved also sleep, sexual functions and quality of life. Both patients and physicians satisfied with the effects of drug. Adverse drug reactions were a few and not serious, and most of them disappeared as treatment continued. CONCLUSION: These results suggest that not only nefazodone has antidepressant effects and antianxiety effects, but also it improves sleep disturbance, sexual dysfunction and the quality of life in depressive patients. Adverse drug reactions were a few and not serious.
Anti-Anxiety Agents
;
Anxiety*
;
Depression*
;
Depressive Disorder, Major
;
Diagnostic and Statistical Manual of Mental Disorders
;
Drug-Related Side Effects and Adverse Reactions
;
Dysthymic Disorder
;
Humans
;
Quality of Life*
;
Surveys and Questionnaires