1.A case of tongue volume measurement with the plaster tongue model for partial glossectomy in macroglossia.
Se Kwang OH ; Won Yong YANG ; Doo Hyung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(4):593-597
The tongue is located inside the oral cavity at rest, and the structural interrelations between the tongue and the oral cavity is essentially important for normal tongue function. Macroglossia is clinically diagnosed whenever the tongue does not fit the oral cavity, thus patients complain of noisy breathing, drooling, speech and swallowing dysfunction, malocclusion, and social ridicule. Partial glossectomy for macroglossia volume has been assumed to be difficult. In this study, we attempted to measure the tongue volume with the plaster tongue model in a 7-year-old macroglossia patient. This method is reliable and simple for measuring the tongue volume in macroglossia.
Child
;
Deglutition
;
Glossectomy*
;
Humans
;
Macroglossia*
;
Malocclusion
;
Mouth
;
Respiration
;
Sialorrhea
;
Tongue*
2.A comparative study of the cranicial complex in korean with Down's syndrome.
Young Chul JANG ; Won Yong YANG ; Doo Hyung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(2):272-293
No abstract available.
Down Syndrome*
3.A Case of Pigmented Dermatofibrosarcoma Protuberans ( Bednar Tumor ) Showing Atrophic Lesions.
Jong Ho LEE ; Doo Yeoul JUNG ; Sook Kyung LEE ; Won Woo LEE
Korean Journal of Dermatology 1998;36(1):139-142
A Bednar tumor is a variant of dermatofibrosarcoma protuberans(DFSP). The clinical and histopathological findings of Bednar tumors are identical to DFSP except for the presence of melanin-containing cells scattered within the lesion, so called pigmented DFSP. The majority of Bednar tumors are seen as DFSP present as multinodular protuberant masses in the skin. They can also present as an atrophic depressed scar-like lesions without any nodularity. We report an uncommon clinical presented case of a Bednar tumor on the back in a 22-year-old female. She presented with an asymptomatic, firm, bluish, chestnut sized, depressed and atrophic lesion on the back which had been present for 6 years. A Histopathological examination revealed massive proliferation of spindle-shaped cells arranged in a tight storiform pattern mixed with scattered pigmented cells. On immunohistochemical staining, the tumor cells were positive for vimentin, a -l-antitrypsin, and CD34, but were negative for cytokeratin, neurofilament, and factor XIIIa. The majority of the tumor cells was negative and the pigment cells were positive for the S-100 protein. The patient was treated by a wide local excision of the lesion. There has been no evidence of recurrence after 20 months post-operative follow up.
Dermatofibrosarcoma*
;
Factor XIIIa
;
Female
;
Follow-Up Studies
;
Humans
;
Keratins
;
Recurrence
;
S100 Proteins
;
Skin
;
Vimentin
;
Young Adult
4.A Case of Cystic Degeneration of Uterine Adenomyosis.
Yang Soo KWAK ; Sang Won LEE ; Ho Joon WHANGBO ; Doo Jin LEE ; Sung Ho LEE
Yeungnam University Journal of Medicine 1994;11(2):405-410
Adenomyosis is a common disease of middle-aged women and adenomyoma is a variety of adenomyosis that formed localized tumor. Cystic degeneration of an adenomyoma is a rare clinical manifestation. A 30-year-old parous woman suffered from severe dysmenorrhea and menorrhagia for about 5 months, was operated under the impression of endometriosis of the pelvis. Following the operation, cystic degeneration of an adenomyoma was found incidentally. The authors experienced a case of adenomyosis that formed cystic tumor of uterus and presented with a pertinent literatures.
Adenomyoma
;
Adenomyosis*
;
Adult
;
Dysmenorrhea
;
Endometriosis
;
Female
;
Humans
;
Menorrhagia
;
Pelvis
;
Uterus
5.Three Cases of Apert Syndrome (Acrocephalosyndactyly).
Young Sil AHN ; Jong Won LEE ; Jin BANG ; Doo Bong LEE
Journal of the Korean Pediatric Society 1994;37(8):1149-1155
Apert syndrome is an uncommon, congenital disorder characterised by malformation of the skull, most often acrocephaly or oxycephaly, in association with symmetrical syndactyly of both hands and feet. It is due to disturbance in the growth of bone and soft tissue affecting principally the head, the hands and the feet. The original description was presented by Troquart in 1886, and acrocephaloyndactyly was named by Apert in 1906. Since then, more than 200 cases have been reported in the world upto 1970. Recently, we have experienced three for typical Apert syndrome and made a brief related literature review
Acrocephalosyndactylia*
;
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
;
Craniosynostoses
;
Foot
;
Hand
;
Head
;
Skull
;
Syndactyly
6.A Case of Malignant Eccrine Poroma.
Doo Yeoul JUNG ; Ju Han BAE ; Sook Kyung LEE ; Won Woo LEE
Korean Journal of Dermatology 1999;37(5):660-664
Malignant eccrine poroma, or eccrine porocarcinoma, is a rare malignant cutaneous appendageal tumor arising from the intraepidermal eccrine sweat duct(acrosyringium), and usually develops ia an eccrine poroma of long-standing. We report a case of malignant eccrine poroma on the left buttock in a 72 year-old female. She was presented with a slightly pruritic, well-defined, reddish, firm, 4.5 x 4.5 x 0.7cm sized, protruding, ulcerated tumor. Histopathological examination revealed well-defined tumor cell nests in the epidermis and dermis. The tumor nests consisted of areas of eccrine poroma cells with benign appearance adjoining areas of anaplastic cells. Duct-like structures were observed within the tumor nests and showed a PAS-positive, diastase-resistant reaction. On immunohistochemical staining, the tumor cells were, positive for EMA, and most of tumor cells were negative but the duct-like structures were positive for CEA. She was treated with surgical excision. During the three year follow up period after excision, there was no recurrence.
Aged
;
Buttocks
;
Dermis
;
Eccrine Porocarcinoma*
;
Epidermis
;
Female
;
Follow-Up Studies
;
Humans
;
Poroma
;
Recurrence
;
Sweat
;
Ulcer
7.Changing pattern of serum leptin concentration in women undergoing clomiphene citrate challenge test or controlled ovarian hyperstimulation.
Doo Seok CHOI ; Jeong Won LEE ; Jin Kyung YOO ; Byung Koo YOON ; Je Ho LEE
Korean Journal of Obstetrics and Gynecology 1999;42(12):2744-2748
OBJECTIVE: To evaluate the changing pattern of serum leptin level and the correlation between estradiol level during the clomiphene citrate challenge test(CCCT) or controlled ovarian hyperstimulation(COH) cycle. METHODS: Twenty-seven women who underwent CCCT and fourteen women who underwent controlled ovarian hyperstimulation were recruited to measure the serum leptin level. After correction of serum concentration with body mass index(BMI), changes of leptin level and correlation with serum estradiol level during CCCT and COH cycle were analyzed. RESULTS: Circulating leptin levels were significantly correlated with BMI at each time point in CCCT cycle(P<0.01). In CCCT cycle, leptin/BMI level was significantly increased at midluteal phase compared to that of menstrual cycle day 3 and 10(p<0.05). In women with regular menstruation, leptin/BMI level at midluteal phase was significantly higher than that of menstrual day 3 and 10, but this difference was not seen in women with irregular menstruation. The leptin/BMI level in COH cycle showed increasing tendency throughout ovarian stimulation. But there was no significant correlation between leptin/BMI and estradiol level in CCCT and COH cycle. CONCLUSION: There is a significant correlation between BMI and circulating leptin level. Midluteal leptin level is significantly higher than that of follicular phase in CCCT cycle, and there is an increasing tendency in leptin level after ovarian stimulation in CCCT and COH cycle without statistical significance. These findings suggest that circulating estradiol concentration has no major influence on circulating leptin level.
Clomiphene*
;
Estradiol
;
Female
;
Follicular Phase
;
Humans
;
Leptin*
;
Menstrual Cycle
;
Menstruation
;
Ovulation Induction
8.Predictive Factors of Seizure Recurrence & Persistence in Benign Epilepsy of Childhood with Centrotemporal Spikes.
Doo Hee HAN ; Hong Jin LEE ; Won Il PARK ; Kyung Ja LEE
Journal of the Korean Child Neurology Society 1998;5(2):258-264
PURPOSE: In order to recognize predictive factors of the recurrent seizure attacks with benign epilepsy of childhood with centrotemporal spike(BECCT), we have studied the factors such as age of seizure onset, sex of the patient, frequency and duration of seizure Prior to therapy, initial antiepileptic drug, which are presumed to influence the recurrence of seizure attack. METHODS: Among the children with BECCT, who visited the department of pediatrics, Chuncheon Sacred Heart hospital, Hallym University from Jan. 1985 to Dec. 1997, 52 patients who were followed up for more than 12 months after disappearance of the seizure, have been studied. The patients were divided into three groups, (group I; seizure duration is less than 3 months, groups II; seizure duration less than 12 months, group III; seizure duration more than 12 months) by duration of seizure recurrence, and compared with difference of seizure recurrence by predicting factor in each group. Data were analysed by using DBSTAT version 1.0 by ANOVA. RESULTS: 1) Age onset of seizure The age onset of seizure in group I is 8.6+/-2.0 years and 7.9 +/-3.5 years in group II, 6.2+/-1.7 years in group III. The younger the seizure standted, the more seizures recurred(p<0.05). Our study revealed no age differences of the seizure remission in 3 groups. 2) Sex : Among the 52 patients, 30 patients were male, 22 patients were female. The ratio of the male to female was 1:1(12/12) in group I, 1:1.5(2/3) in group II, 2.3: 1(16/7) in group III. The recurrence rate was higher in male than in female. But no statistically difference in recurrence rate by the sex was revealed. 3) Seizure duration and seizure frequency prior to therapy : In group I, pretreatment duration was 1.6+/-3.5 months, frequency of the attacks was 2.0+/-1.0. In group II, duration 1.3+/-1.2 months, frequency 3.2+/-0.5. In group III, duration 3.5+/-6.9 months, frequency 3.5+/-1.8. Our study revered statistically significant differences in values of frequencies and durations in each groups(p<0.05). 4) Initial anticonvulsant and seizure recurrence : Seizure recurred in 36% of patients treated by carbamazepine, and 55.6% of valproate, 66.7% of phenobarbital, 37.5% of diphenylhydantion. There was no significant relation between initial anticonvulsant and seizure recurrence in each group. CONCLUSION: Our data support that age onset and seizure frequency were predictive factor fort seizure recurrence. BECCT Is a age dependent genetic disorder with variable penetrance, having longer duration of seizure with earlier onset. Clinical seizures and abnormal EEG trait tend to remit at certain age, regardless of onset age and treatment.
Age of Onset
;
Carbamazepine
;
Child
;
Electroencephalography
;
Epilepsy
;
Epilepsy, Rolandic*
;
Female
;
Gangwon-do
;
Heart
;
Humans
;
Male
;
Pediatrics
;
Penetrance
;
Phenobarbital
;
Recurrence*
;
Seizures*
;
Valproic Acid
9.Two Cases of Kayser-Fleischer Rings.
Doo Suck LEE ; Gi Gen ON ; Jae Duck KIM
Journal of the Korean Ophthalmological Society 1987;28(1):177-183
The Kayser-Fleischer ring, a characteristic finding in Wilson's disease, occurs in the corneal periphery and is usually yellow-brown but may by red, blue, green, ormixture of any these colors. The Kayser-Fleischer ring, copper deposition at the level of the posterior position of Descemet's membrane, is about 1 to 3mm in width and extends to the limbus without a lucid interval. In addition to involvement of Descemet's membrane, one may find anterior subcapsular sunflower cataract in Wilson's disease. The authors have recently experienced two cases of Wilson's disease. One case, a 17-year-old boy, has Kayser-Fleischer rings and anterior subcapsular sunflower cataracts in both eyes and the other, a 17-year-old aldolescent male, has dense yellow-green colored Kayser-Fleischer rings in both eyes. Both cases have been treated with penicillamine(1gr/day) and low copper diet. After treatment, clinical manifestations have been improved markedly but the Kayer-Fleischer rings have not disappeared yet.
Adolescent
;
Cataract
;
Copper
;
Descemet Membrane
;
Diet
;
Helianthus
;
Hepatolenticular Degeneration
;
Humans
;
Male
10.A Case of Dermatitis Artefacta Treated with Pimozide.
Jeong Aee KIM ; Hee Chul EUN ; Won Suk KIM ; Yoo Shin LEE ; Doo Young CHO
Korean Journal of Dermatology 1986;24(1):102-106
We report a case of 64-year-old female patient who has had factitious skin lesions for 20 years. She complained formification sense and severe itching on her face. These symptoms were improved with squeezing and bleeding. There were scuare shaped ulcerated nodule on the right cheek and white depressed scar on the left cheek. She was treated with wet dressing and occlussive dressing, and skin lesions were nearly cleared within 3 weeks, but new lesion appeared. Pimozide 2mg #1 p.o were given under the diagnosis of delusion of parasitosis from June, 1984. Her symptoms were improved without recurrence till now. Treatment with pimozide in monosymptomatic hypochondriacal syndrome is discussed.
Bandages
;
Cheek
;
Cicatrix
;
Delusions
;
Dermatitis*
;
Diagnosis
;
Female
;
Hemorrhage
;
Humans
;
Middle Aged
;
Pimozide*
;
Pruritus
;
Recurrence
;
Skin
;
Ulcer