1.Knowledge of orthodontics and malocclusion.
Won You LEE ; Hyung Don KIM ; Bu Suk HAN
Korean Journal of Orthodontics 1992;22(4):815-822
Orthodontists want why the patients want orthodontic treatment. Demand and need for orthodontics is very important factors of cooperation and management. Chief complaint would be different according to the race and culture. Our results show that in the control group, Korean female adolescents[chief complaint is cowding(30.6%), spacing(26.5%), upper anterior protrusion(18.4%), anterior cross bite(8.2%) in order. Korean female adolescents considered anterior cross bite is more nonacceptable than spacing and anterior protrusion. The purpose of orthodontics seemed to enhance esthetic, dental health, and to improve oral function.
Adolescent
;
Continental Population Groups
;
Esthetics, Dental
;
Female
;
Humans
;
Malocclusion*
;
Orthodontics*
2.New Selective Medium for Rapid Identification of Vibrio vulnificus from Patients with V. vulnificus Sepsis.
Dong O YOU ; Sang Won JEONG ; Seok Don PARK
Korean Journal of Dermatology 2003;41(6):696-701
BACKGROUND: Vibrio(V.) vulnificus is a halophilic, gram-negative bacillus that causes a fatal sepsis in patients with underlying chronic disease such as liver cirrhosis and alcoholic abuse. Because V. vulnificus infection has a fulminant course and high mortality rate, early recognition and rapid diagnosis with prompt therapy are necessary to improve survival rate. OBJECTIVE: The purpose of this study was to develop a new selective medium for rapid identification of V. vulnificus through color change of medium according to pH from patients suspected of having V. vulnificus sepsis. METHODS: Rapid isolation and identification of V. vulnificus can be possible by modifying the component of PNC(5% peptone, 1% NaCl, and 0.08% cellobiose [pH 8.0]) broth medium. From this PNC broth, a basal broth(5% peptone+1% NaCl+cellobiose) was prepared and used to evaluate additional medium supplements(cellobiose concentration [0.08, 0.2, 0.1%], pH [6.8, 7.5, 8.0] and pH indicator dye [bromthymol blue, thymol blue, phenol red, bromcresol purple, crystal violet, cresol red, and neutral red]). To examine the rapid identification and selectivity of this basal medium according to various conditions, V. vulnificus was tested by using saline and normal human blood containing these bacteria(1, 000 bacteria/ml), respectively at 37degrees C. A positive reaction(V. vulnificus growth) appeared as color change. The selectivity and identification capacity of this new broth was tested by using other 6 Vibrio species and 14 strains of other bacteria. RESULTS: Color change appeared only in the medium including bromthymol blue and thymol blue as a pH indicator dye. It was called the basal medium containing blue dyes as PNCB(peptone, NaCl, cellobiose and blue dye) medium. It took an average time of 4.8hr for becoming aware of yellow color change in PNCB broth after cultivating with saline mixed with V. vulnificus and 6hr in PNCB broth after cultivating with blood mixed with V. vulnificus. One Vibrio species and another 3 bacteria produced color change. So we confirmed that the final composition and pH of PNCB broth medium was 5% peptone, 1% NaCl, 0.2% cellobiose, 0.0004% bromthymol blue and 0.0004% thymol blue [pH 7.5] CONCLUSIONS: PNCB broth could be used as a selective and differential medium for rapid isolation and identification of V. vulnificus in patients with V. vulnificus sepsis.
Alcoholics
;
Bacillus
;
Bacteria
;
Bromcresol Purple
;
Bromthymol Blue
;
Cellobiose
;
Chronic Disease
;
Coloring Agents
;
Diagnosis
;
Gentian Violet
;
Humans
;
Hydrogen-Ion Concentration
;
Liver Cirrhosis
;
Mortality
;
Peptones
;
Phenolsulfonphthalein
;
Sepsis*
;
Survival Rate
;
Thymol
;
Vibrio vulnificus*
;
Vibrio*
3.Effect of maxillary expansion appliance using magnetic attraction force.
Won You LEE ; Ji Cheul JANG ; Hyoung Don KIM ; Bu Seuk HAN
Korean Journal of Orthodontics 1991;21(3):603-613
To study the possibility of attraction magnetic forces to expand maxillary arch, we used 2 big adult dogs, 2 small puppies, 1 small adult dog as experiments, and 1 small adult dog as a control. We measured the intercanine width and intermolar width and histologically observed in the suture and cervical and apex region of teeth and took occlusal X-rays to observe separation of suture line in the maxilla. The results were as follows: 1. Expansion velocities of intercanine (0.25mm/day) and intermolar widths (0.23mm/day) in puppies were faster than those (0.135mm/day, 0.09mm/day) in adults. 2. In all experiments in adults (0.135mm/day) and puppies (0.25mm/day), expansion velocity of intercanine widths were faster than those (0.09mm/day, 0.23mm/day) of intermolar width. 3. In all experiments ectatic changes were observed and cellularities of fibroblast increased in the suture line. Only in adults dogs the separations of palatal suture were observed in the occlusal X-ray view. 4. In the puppies bony deposition was particularly observed in the suture line and micro-bony fragments were often observed. 5. In the all experiments no root resorption was observed in the cervical and root area, but normal root resorption due to eruption of permanent teeth was observed in the puppies.
Adult
;
Animals
;
Dogs
;
Fibroblasts
;
Humans
;
Maxilla
;
Palatal Expansion Technique*
;
Root Resorption
;
Sutures
;
Tooth
4.Transthoracic Fine Needle Aspiration Biopsy: Diagnostic Rate and Complications in 1000 Cases.
Yo Won CHOI ; Seok Chol JEON ; Chang Kok HAHM ; Oh Keun BAE ; Sun Mi KIM ; Chang Ho KIRN ; Won Don YOU
Journal of the Korean Radiological Society 1994;31(5):897-900
PURPOSE: Transthoracic fine needle aspiration biopsy is a widely practiced technique in the investigation of the lung and mediastinal masses because of its safety, reliability and accuracy. We report the diagnostic accuracy of the transthoracic fine needle aspiration biopsy and the frequency of its complications which required treatment. MATERIALS AND METHODS: We analyzed 1000 transthoracic needle aspiration biopsies whcih were performed in 986 patients with 993 chest lesions. Aspiration biopsies were obtained with Westcott needles (20G or 22G) under the fluoroscopic guidance. Final diagnosis was made with operation, bronchoscopy, sputum study, biopsy of other sites and the clinical course of the patient. We analyzed diagnostic yields of aspiration biopsy and the frequency of the complication requiring treatment. RESULTS: The sensitivity was 87.6% in benign diseases and 95.8% in malignant diseases. Pneumothorax was the most frequent complication, which required pig-tail catheter insertion in 36 cases or thoracostomy in six cases. In 36 cases, minimal hemoptysis developed which did not require treatments. CONCLUSION: We obtained relatively high sensitivities of malignant and benign lesions using transthoracic fine needle aspiration biopsy and the frequency of the complications requiring treatment was very low. Transthoracic fine needle aspiration biopsy is a valuable diagnostic method in the thoracic lesions.
Biopsy*
;
Biopsy, Fine-Needle*
;
Biopsy, Needle
;
Bronchoscopy
;
Catheters
;
Diagnosis
;
Hemoptysis
;
Humans
;
Lung
;
Needles
;
Pneumothorax
;
Sputum
;
Thoracostomy
;
Thorax
5.A Case of Hemophilus Paraphrophilus Endocarditis with Cerebral Embolism and Hemorrhage.
Kyong Hoon YOU ; Sang Hun KIM ; Hee Jung CHOI ; Myoung Don OH ; Dae Won SOHN ; Eui Chong KIM ; Yun Shik CHOI ; Kang Won CHOE
Korean Circulation Journal 1998;28(4):642-646
Infective endocarditis by Hemophilus species is very rare:there are only 22 reported-cases of Hemophilus paraphrophilus endocarditis. We report a case of Hemophilus paraphrophilus endocarditis in a middle-aged woman with cerebral embolism and hemorrhage.
Endocarditis*
;
Female
;
Haemophilus
;
Haemophilus paraphrophilus*
;
Hemorrhage*
;
Humans
;
Intracranial Embolism*
6.Contact Dermatitis due to Ketoprofen Patch(Ketotop(R)).
Nyoung Hoon YUN ; Dong O YOU ; Sang Won LEE ; Seok Don PARK ; Seung Hoon CHA
Korean Journal of Dermatology 2001;39(7):794-797
Ketoprofen is an nonsteroidal anti-inflammatory drug derived from propionic acid. It has been widely used as topical preparations, as gel or patch. It has been reported that topical ketoprofen can cause contact dermatitis and photocontact dermatitis. We experienced five cases of contact dermatitis, developed after applying ketoprofen patch(Ketotop(R), Pacific pharmaceutical Co., Korea) for the control of oste omuscular or joint pain. While one patient had generalized urticarial eruption, the rest of patents showed localized erythematous pruritic eczematous skin eruptions. It was verified through intradermal skin test and pin prick test that ketoprofen itself was not the causative drug for the skin eruption. Patch test excluded the possibility of allergic skin reaction to rubber compounds. It should be elucidated which compounds are allergic or toxic to the skin, contained in woven fabrics.
Arthralgia
;
Dermatitis, Contact*
;
Dermatitis, Photoallergic
;
Diethylpropion
;
Humans
;
Ketoprofen*
;
Patch Tests
;
Rubber
;
Skin
;
Skin Tests
7.Two Cases of Chemical Burns by Hydrofluoric Acid.
Sung Won JANG ; You Dong SOHN ; Myung Don JU ; Woo Ik CHOI
Journal of the Korean Society of Traumatology 2006;19(2):173-177
Hydrofluoric acid is a colorless gas or fuming liquid with a strong, irritating odor. Hydrofluoric acid burns are uncommon; however, if severe burn occur, they caused death from systemic effects, such as fatal cardiac arrthmia. We experienced two cases of hydrofluoric acid chemical burns on digits. These patients had typical clinical features of hydrofluoric acid chemical burns, such as pulsating pain at the burn site, as well as ischemic and necrotic skin changes. The hydrofluoric acid chemical burn was confirmed by a history of exposure. Subsequently, we made a calcium gluconate gel by mixing 20% calcium gluconate, an antagonist against hydrofluoric acid, with lubricant, and we injected 10% calcium gluconate subcutaneously when they complained of pain rated at higher than 5 on the pain scale. Simultaneously, we monitored the patients' electrocardiographs and checked their serum total calcium, ionized calcium, and magnesium levels serially. Clinical presentations and the emergency management of hydrofluoric acid chemical burns were reviewed along with the current literature. These patients were discharged without any significant complications.
Burns
;
Burns, Chemical*
;
Calcium
;
Calcium Gluconate
;
Electrocardiography
;
Emergencies
;
Humans
;
Hydrofluoric Acid*
;
Magnesium
;
Odors
;
Skin
8.Two Cases of Chemical Burns by Hydrofluoric Acid.
Sung Won JANG ; You Dong SOHN ; Myung Don JU ; Woo Ik CHOI
Journal of the Korean Society of Traumatology 2006;19(2):173-177
Hydrofluoric acid is a colorless gas or fuming liquid with a strong, irritating odor. Hydrofluoric acid burns are uncommon; however, if severe burn occur, they caused death from systemic effects, such as fatal cardiac arrthmia. We experienced two cases of hydrofluoric acid chemical burns on digits. These patients had typical clinical features of hydrofluoric acid chemical burns, such as pulsating pain at the burn site, as well as ischemic and necrotic skin changes. The hydrofluoric acid chemical burn was confirmed by a history of exposure. Subsequently, we made a calcium gluconate gel by mixing 20% calcium gluconate, an antagonist against hydrofluoric acid, with lubricant, and we injected 10% calcium gluconate subcutaneously when they complained of pain rated at higher than 5 on the pain scale. Simultaneously, we monitored the patients' electrocardiographs and checked their serum total calcium, ionized calcium, and magnesium levels serially. Clinical presentations and the emergency management of hydrofluoric acid chemical burns were reviewed along with the current literature. These patients were discharged without any significant complications.
Burns
;
Burns, Chemical*
;
Calcium
;
Calcium Gluconate
;
Electrocardiography
;
Emergencies
;
Humans
;
Hydrofluoric Acid*
;
Magnesium
;
Odors
;
Skin
9.Recanalization Rate and its Associated Factors after Intravenous Tissue Plasminogen Activator Thrombolysis for Acute Major Cerebral Arterial Occlusion.
Won Ki YOON ; Young Woo KIM ; Sung Rhim KIM ; Seung Hoon YOU ; Ik Sung PARK ; Sang Don KIM ; Min Woo BAIK
Korean Journal of Cerebrovascular Surgery 2007;9(4):265-270
PURPOSE: To investigate the recanalization rate after intravenous administration of recombinant tissue plasminogen activator (IV-tPA) for acute major arterial occlusion of the anterior cerebral circulation and to investigate the relationship between atrial fibrillation and recanalization. METHODS: From April 2005 to April 2006, 16 patients with acute major arterial occlusion of the anterior cerebral circulation were treated with IV-tPA. Recanalization was classified as good (as compared with an unoccluded contralateral vessel; thrombolysis in myocardial infarction (TIMI) classification grade II and III) and poor (TIMI grade 0 and I). The clinical and radiological parameters associated with recanalization were analyzed. The clinical outcomes were evaluated by use of the National Institute of Health Stroke Scale (NIHSS) at 3 months after treatment. RESULTS: Of all of the 16 patients, 11 patients (68.8%) showed good recanalization. Among these 11 patients, nine patients survived (81.8%). However, only one patient survived (20%, p = 0.036) of the other five patients who showed poor recanalization. The pretreatment NIHSS score and atrial fibrillation were significantly correlated with the recanalization rate. Atrial fibrillation was found in 8 of 16 patients (50.0%) as the cause of the cerebral embolic infarction. Among the patients with atrial fibrillation only three patients showed good recanalization (37.5%); patients without atrial fibrillation showed good recanalization (100%, p = 0.026). CONCLUSIONS: I.-tPA appears to be effective and safe as a recanalization method for acute major cerebral arterial occlusion in patients that do not have atrial fibrillation. Good recanalization was associated with a good clinical result. Atrial fibrillation is a significant associated factor of poor recanalization and high mortality.
Administration, Intravenous
;
Atrial Fibrillation
;
Classification
;
Humans
;
Infarction
;
Mortality
;
Myocardial Infarction
;
Stroke
;
Tissue Plasminogen Activator*
10.Is Extravasation of Radiographic Contrast a Predictor of Hematoma Enlargement in Spontaneous Supratentorial Intracerebral Hemorrhage?.
Young Woo KIM ; Won Ki YOON ; Seoung Rim KIM ; Sang Don KIM ; Ik Seong PARK ; Min Woo BAIK ; Seung Hoon YOU
Korean Journal of Cerebrovascular Surgery 2007;9(4):252-258
BACKGROUND AND PURPOSE: The enlargement of a hematoma occurs commonly in patients with spontaneous intracerebral hemorrhage (ICH) after hospitalization and can worsen the clinical outcome. We conducted this study to determine whether extravasation of a radiographic contrast agent is a predictor of hematoma enlargement occurring after admission in patients with spontaneous ICH. METHODS: We reviewed the clinical records and computerized tomography (CT) scan findings of 384 patients with spontaneous ICH admitted within 24 hours of ictus from 2002 to 2005. Only 71 patients with primary ICH in the basal ganglia or thalamus were included in the study. The first CT scan was preformed within 24 hours of onset and the second CT scan was preformed within 72 hours of onset. We compared patients with and without hematoma enlargement according to the radiological findings, clinical characteristics and laboratory data. RESULTS: Seventeen patients (23.9%) showed hematoma enlargement after admission. Extravasation of the radiographic contrast agent on a CT scan was seen in 23 patients (32.4%). The presence of contrast extravasation on a CT scan closely correlated with evidence of hematoma enlargement, as seen on a follow-up CT scan (p = 0.000). Other variables did not reach statistical significance for the independent association with hematoma enlargement. CONCLUSIONS: Due to a high risk for hematoma enlargement, patients with spontaneous ICH in the basal ganglia and thalamus, especially those with evidence of contrast extravasation on a CT scan, should be closely observed. Short term followup radiological studies are needed for the verification of hematoma enlargement.
Basal Ganglia
;
Cerebral Hemorrhage*
;
Follow-Up Studies
;
Hematoma*
;
Hospitalization
;
Humans
;
Thalamus
;
Tomography, X-Ray Computed