1.Incidence of sepsis associated with total parenteral nutrition solutions made in the nursery and pharmacy.
Moon Chan KIM ; Jin Won PARK ; Yun Joo CHUNG
Journal of the Korean Pediatric Society 1992;35(5):646-651
No abstract available.
Incidence*
;
Nurseries*
;
Parenteral Nutrition, Total*
;
Pharmacy*
;
Sepsis*
2.Studies on the Changes of Serum Osmolality Electrolytes, Digoxin-like Substance and Plasma Renin Activity Following Angiocardiography using Hypertonic Contrast Media.
Heon Seob SONG ; Hyeong Won SHIN ; Chan Uhung JOO ; Dae Yeol LEE ; Jin Gon JUN
Journal of the Korean Pediatric Society 1987;30(4):398-405
No abstract available.
Angiocardiography*
;
Contrast Media*
;
Electrolytes*
;
Osmolar Concentration*
;
Plasma*
;
Renin*
3.Pseudo - Kaposi' s Sarcoma Developing After Placement of A - V Fistula for Hemodialysis.
Beom Joo LEE ; Soo Chan KIM ; Sung Ku AHN ; Won Soo LEE
Korean Journal of Dermatology 1994;32(2):358-361
Pseudo-Kaposis sarcoma is a self-limited process associated with vascular malformations, without the neoplastic character of real Kaposis sarcoma. In most cases, it has been associated with an underlying congenital arterial venous fistula and chronic venous insufficiency, We present a case of Pseudo-Kaposis's sarcoma developing after plagment of arteriovenous fistula for hemodialysis in a patient wiith chronic renal failure and review cases reported in articles.
Arteriovenous Fistula
;
Fistula*
;
Humans
;
Kidney Failure, Chronic
;
Renal Dialysis*
;
Sarcoma*
;
Sarcoma, Kaposi
;
Vascular Malformations
;
Venous Insufficiency
4.Clinical study of Outcome and Predisposing Factors for Spontaneous Pneumothorax in the Neonates.
Byung Joo CHOI ; Jo Won JUNG ; Seon Chan BAE ; Moon Sung PARK ; Jeong In YANG
Korean Journal of Perinatology 2000;11(4):438-444
No abstract available.
Causality*
;
Humans
;
Infant, Newborn*
;
Pneumothorax*
5.Effects of Bupivacaine on the Membrane Potential and Intracellular Na.
Chan Uhng JOO ; Won Ho KIM ; Jae Ki KO ; Sang Kyi LEE ; Soo Wan CHAE
Korean Circulation Journal 1997;27(8):870-875
BACKGROUND: Bupivacaine is a potent, and commonly used, long acting local anesthetic. If accidentally injected into the systemic circulation, bupivacaine can cause lethal dysrhythmias and circulatory collapse. Attempts to treat bupivacaine induced cardiac toxicity have been varied and controversial, and they have not been very successful. The aim of this study was to investigate the electrophysiologic effects of bupivacaine in Purkinje fibers. METHODS: Effects of bupivacaine on the membrane potential were studied in 12 isolated canine Purkinje fibers. Purkinje fibers from ventricle were dissected and mounted in a tissue chamber perfused with Tyrode's solution. Transmembrane potentials recorded through glass microelectrodes filled with 3M KCI in the beating or quiescent Purkinje fibers during infusions of bupivacaine at concentratons of 3*10/-7M,10/-6M, 3*10/-6M,10/-5M, and 3*10/-5M. RESULTS: Bupivacaine reduced action potential druation in a dose-dependent manner. Bupivacaine produced a decrease in intracelullar sodium ion activity in driven(1Hz) and quiescent canine Purkinje fibers. Bupivacaine-induced hyperpolarizaton of diastolic membrane potential in quiescent Purkinje fibers was dose dependent, and the hyperpolarization by bupivacaine was attenuated by depolarization induced by high potassium extracellular concentration in part. CONCLUSIONS: These results suggest that bupivacaine decreases the fast inward sodium current, and inhibits pacemaker current in canine Purkinje fibers.
Action Potentials
;
Bupivacaine*
;
Glass
;
Membrane Potentials*
;
Membranes*
;
Microelectrodes
;
Potassium
;
Purkinje Fibers
;
Shock
;
Sodium
;
Sodium Channels
6.Three cases of earty dyskeratoma.
Il Joo LEE ; Won HUR ; Sung Ku AHN ; Won Soo LEE ; Soo Chan KIM ; Seung Hun LEE
Korean Journal of Dermatology 1992;30(4):564-568
Warty dyskeratoma is a rare, well-circumscribed epidermal tumor that frequently aries as a single lesion on the skin of the head or neck of middle aged or older persons. Its histopathological features include : suprabasilar clefting with villous proliferations of the connective tissue papillae into the clefts ; acantholytic and dyskeratoic epithelial cells,basilar hyperplasia, and hyperleratosis. We report three cases of warty dyskeratoma describing clinical and histochemical fea tures.
Connective Tissue
;
Head
;
Humans
;
Hyperplasia
;
Middle Aged
;
Neck
;
Skin
7.Colonoscopic Diagnosis of Whipworm Infection.
Sung Won CHO ; Chan Sup SHIM ; Joon Seong LEE ; Moon Sung LEE ; Chan Wook PARK ; Dong Wha SONG ; Jae Hak JOO ; Kwon Ho RYU ; Young Hong LEE
Korean Journal of Gastrointestinal Endoscopy 1994;14(4):489-493
Trichuriasis is an intestinal infection of human beings caused by Trichuris trichiura, more commonly known as whipworm because of its whip-like appearance. It is characterized by the invasion of the colonic mucosa by the adult trichuris. It is prevalent throughout the world, especially in tropical areas. Diagnosis is made typically by the identification of characteristic barrel-shaped eggs in the feces, although adult worms may be seen rarely at sigmoidoscopy or colonoscopy. We report five cases of whipworm infection that was diagnosed on colonoscopic examination.
Adult
;
Colon
;
Colonoscopy
;
Diagnosis*
;
Eggs
;
Feces
;
Humans
;
Mucous Membrane
;
Ovum
;
Sigmoidoscopy
;
Trichuriasis
;
Trichuris
8.Effects of GnRH Agonist Used for Ovarian Hyperstimulation in Human IVF-ET on the Apoptosis of Preovulatory Follicular Cells.
Hyun Won YANG ; Hyuck Chan KWON ; Kyung Joo HWANG ; Jong Min PARK ; Kie Suk OH ; Yong Dal YOON
Korean Journal of Fertility and Sterility 1999;26(1):55-65
There have been many reports to date regarding the role of GnRH as a local regulatory factor of ovarian function as studies of human and rat ovaries revealed GnRH and its receptor. In recent studies it has been shown that GnRH directly causes apoptosis in the granulosa cells of the rat ovary, and such results leads to the suggestion that the use of GnRH agonist for more stable long term ovarian hyperstimulation in human IVF-ET programs causes granulosa cell apoptosis which may lead to follicular atresia. Therefore this study attempts to determine if granulosa-luteal cell apoptosis occurs in patients during IVF-ET programs in which GnRH agonist is employed for ovarian hyperstimulation. The quality of oocyte-cumulus complexes obtained during ovum pickup procedures were assessed morphologically and then the fertilization rate and developmental rate was determined. Apoptotic cells among the granulosa-luteal cells obtained during the same procedure were observed after staining with Hematoxylin-rosin. The fragmentation degree of DNA extracted from granulosa-luteal cells was determined and comparatively analyzed. There was no difference in the average age of the patients, the number of oocytes retrieved, and fertilization and developmental rates between the FSH/hMG group and GnRH-long group. There was also no difference in the apoptosis rate and pyknosis rate in the granulosa-luteal cells between the two groups. However, when the oocyte-cumulus complexes were morphoogically divided into the healthy group and atretic group without regard for the method of hyperstimulation, the results showed that the number of oocytes obtained averaged 11.09+/-8.75 and 10.33+/-4.53 per cycle, respectively, showing no significant difference, but the fertilization rate (77.05%, 56.99%, respectively, p<0.01) and developmental ,ate (65.96%, 41.51%, respectively, p<0.01) was significantly increased in the healthy group when compared to the atretic group. The degree of apoptosis in the granulosa-luteal cells showed that in the healthy group it was 2.25% which was not significantly different from the atretic group (2.77%), but the pyknosis rate in the atretic group (27.81%) was significantly higher compared to the healthy group (11.35%, p<0.01). The quantity of DNA fragmentation in the FSH/hMG group was 32.22%, while in the GnRH-long group it was 34.27%, showing no significant difference. On the other hand the degree of DNA fragmentation was 39.05% and 11.83% in the healthy group and atretic group, respectively, showing significantly higher increase in the atretic group (p<0.01). The above results suggest that death of granulosa-luteal cells according to the state of the oocyte-cumulus complex is more related to pyknosis rather than apoptosis. Also, the GnRH agonist used in ovarian hyperstimulation does not seem to directly affect the apoptosis of retrieved oocytes and granulosa-luteal cells, and which is thought to be due to the suppression of the apoptogenic effect of GnRH agonist as a result of the high doses of FSH administered.
Animals
;
Apoptosis*
;
DNA
;
DNA Fragmentation
;
Female
;
Fertilization
;
Follicular Atresia
;
Gonadotropin-Releasing Hormone*
;
Granulosa Cells
;
Hand
;
Humans*
;
Luteal Cells
;
Oocytes
;
Ovary
;
Ovum
;
Rats
9.Endoscopic Variceal Ligation for Treatment of Bleeding Esophageal Varices.
Chan Sup SHIM ; Joo Young CHO ; Jae Dong CHOI ; Moon Sung LEE ; Jin Hong KIM ; Sung Won CHO
Korean Journal of Gastrointestinal Endoscopy 1992;12(1):1-8
Endoscopic injection sclerotherapy(EIS) is currently the most widely practiced method for treating and eradicating acutely bleeding esophageal varices in repeated sessions, but may be associated with some uadesirable local and systemic complications. Endoscopic variceal ligation(EVL), which consists of mechanical ligation and thrombosis of varices using elastic "0"- rings, has been recently developed as a non-operative alternative to EIS. We performed EVL in 16 patients who had recently bled from esophageal varices. Total 249 variceal ligations were performed during 71 separate EVL sessions. Three patients were actively bleeding at initial EVL; all of them were successfully controlled by emergency EVL. During the study period two patients died after initial EVL; one who refused te return for repeated EVL died from rebleeding, the other died from hepatic failure without any rebleeding. Rebleeding, following initiation of EVL, occured in 3 patients(l8.8%); two patients had bled from varices except previousiy ligated site and were successfully controlled by emergency EVL, remained one who refused any repeat endoscopy could not be confirmed the bleeding site. Varices were eradicated or reduced to grade I in 10(71.4%) of the 14 survivors by 14-28 ligations(mean, 19.5 ligations) in 3 -7 EVL sessions(mean, 5.4 sessions), During or after EVL, there were no complications, except transient mild dysphagia in 3 patients of 16 patients. These results indicated that EVL is a safe and effective method for treatmet of bleeding esophageal varices.
Deglutition Disorders
;
Emergencies
;
Endoscopy
;
Esophageal and Gastric Varices*
;
Hemorrhage*
;
Humans
;
Ligation*
;
Liver Failure
;
Survivors
;
Thrombosis
;
Varicose Veins
10.The clinical application of fetal echocardiography ; The usefulness of four-chamber view as a screening test.
Yong Won PARK ; Jae Sung CHO ; Kyung Joo HWANG ; Jong Kyun LEE ; Jun Hee SUL ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1993;36(10):3558-3564
No abstract available.
Echocardiography*
;
Mass Screening*