1.The Prognostic Significance of p53 Protein and PCNA in Advanced Gastric Carcinoma.
Korean Journal of Pathology 1995;29(4):450-458
The 5 year-survival rates were examined to evaluate the prognositic significance of the expression of the p53 protein and the positivity of the PCNA in 108 cases of advanced gastric carcinoma. The p53 protein and PCNA were stained by immunohistochemistry in the tissue of the gastrectomized specimen. The results were as follows. 1) The overall 5 year-survival rate of advanced gastric carcinoma was 42.3 % and the significant prognostic factors were a pathologic stage and p53 protein(p<0.005). 2) The expanding or infiltrating type by Ming's classification and the intestinal or difftise type by Lauren's classification had similar prognosis. 514_ @@l %R-t 3) The 5 year-survival rate of the p53-positive group was 25.1% and that of p53-negative group was 56.1%(p<0.005). 4) The 5 year-survival rate of the PCNA low-grade tumors by PCNA stain(<50%)was 48.7% and that of the high-grade tumor(>=50%)was 29.9%(p>0.1). 5) There was a tendency to have a good prognosis in the p53-negative group and low grade tumors in the stage 11, III, and IV. There was a significant difference between p53 protein positive and negative groups in the stage III(p<0.005), but no significant differences were found in the other groups. The above results indicate that the p53 protein is an another useful tool for prediction of the prognosis in advanced gastric carcinoma.
Stomach Neoplasms
2.A case of typhoid fever complicated by complete AV block, myocarditis and pancreatitis.
Yoo Bae AHN ; Yang Lee KIM ; Jin Hong YOO ; Wan Shik SHIN ; Moon Won KANG
Korean Journal of Infectious Diseases 1993;25(3):245-248
No abstract available.
Atrioventricular Block*
;
Myocarditis*
;
Pancreatitis*
;
Typhoid Fever*
3.A Case of Rhizomelic Chondrodysplasia Punctata.
Yeon Dong LEE ; Moon Young SONG ; Hyun Hi KIM ; Seung Hoon HAN ; Won Bae LEE
Journal of the Korean Pediatric Society 1994;37(9):1312-1316
Chondrodysplasia punctata is a rare congenital disorder of bone, occuring in infants, which is characterized by radiographic manifestation of premature deposition of punctate calcific densitiy in epiphyseal areas, preformed in cartilage. We experienced a case of rhizomelic type-chondrodysplsia punctata in a two day old female who showed short stature, symmetric shortening of proximal limbs, cataract, icthyositic skin lesion and characteristic coronal clefts in lumbar vertebral bodies on X-ray.
Cartilage
;
Cataract
;
Chondrodysplasia Punctata
;
Chondrodysplasia Punctata, Rhizomelic*
;
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
;
Extremities
;
Female
;
Humans
;
Infant
;
Skin
4.Overexpression and Purification of p24 and gp41 Proteins of Human Immunodeficiency Virus Type 1 in E. coli.
Chae Young KIM ; Soon Cheon SHIN ; Sung Hee LEE ; Won Bae KIM ; Byong Moon KIM
Journal of the Korean Society of Virology 1998;28(1):21-30
Synthetic genes encoding the gag p24 and the part of the envelope protein gp41 of the human immunodeficiency virus (HIV-1) were cloned and overexpressed as fusion proteins in Escherichia coli, using an expression vector carrying 77 promoter and the poly-histidine leader sequence. The overexpressed p24 fusion protein was purified by centrifugation, Ni-affinity chromatography and CM-sepharose chromatography The overexpressed gp41 fusion protein was purified by centrifugation, C4 chromatography and DEAE-sepharose chromatography. The purified fusion proteins showed a high level of purity and immunoreactivity in SDS-polyacrylamide gel electrophoresis and western blot analysis. These results suggest that this prokaryotic expression-purification method is suitable for obtaining a large amount of the viral antigen which may be useful for screening of antibodies to HIV-1 in human blood samples.
Antibodies
;
Blotting, Western
;
Centrifugation
;
Chromatography
;
Clone Cells
;
Electrophoresis
;
Escherichia coli
;
Genes, Synthetic
;
HIV*
;
HIV-1*
;
Humans*
;
Mass Screening
5.Primary Malignant Melanoma arising in Mucosa of the Palatine Tonsil: A case report.
Ki Jung YUN ; Hyang Jeong JO ; Hyung Bae MOON ; Sang Won YOON
Korean Journal of Pathology 1996;30(1):65-67
Maligant melanomas of the oral or nasal cavity, and the vulvovaginal area are relatively common among the melanomas of non-ocular mucosa. But, primary malignant melanoma arising in the mucosa of the palatine tonsil is rare. We present a case of primary malignant melanoma arising in the mucosa of the palatine tonsil. A 36-year-old male was admitted for evaluation of a recurrent sore throat. Tonsillectomy was performed on the basis of clinical suspicion of chronic tonsillitis. Grossly, the left tonsil was focally dark. Microscopically, the tonsillar mucosa was diffusely infiltrated with tumor cells. Tumor cells revealed numerous melanin pigments. Intraepithelial nests of tumor cells were noted, but pagetoid spread of tumor cells was not found. Tumor cells were positive for S-100 protein and HMB45 stain. There was no evidence of melanoma in the skin or eye.
Male
;
Humans
6.In situ saphenous vein arterial bypass: A case report.
Nam Chool MOON ; Byung Woo BAE ; Sang Hyeob JEON ; Jong Won KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(11):881-885
No abstract available.
Saphenous Vein*
7.Clear Cell Basal Cell Carcinoma Arising in Pre-existing Nevus Sebaceus.
Chae Young WON ; Hanmi JUNG ; Ji Hae LEE ; Jung Min BAE ; Kyung Moon KIM
Korean Journal of Dermatology 2016;54(10):836-837
No abstract available.
Carcinoma, Basal Cell*
;
Nevus*
8.A Case of Borst-Jadassohn Pheonomenon Represented in Bowen Disease.
Hanmi JUNG ; Chae Young WON ; Hyerim KO ; Ji Hae LEE ; Jung Min BAE ; Kyung Moon KIM
Korean Journal of Dermatology 2016;54(2):162-163
No abstract available.
Bowen's Disease*
9.Clinical study of Outcome and Predisposing Factors for Spontaneous Pneumothorax in the Neonates.
Byung Joo CHOI ; Jo Won JUNG ; Seon Chan BAE ; Moon Sung PARK ; Jeong In YANG
Korean Journal of Perinatology 2000;11(4):438-444
No abstract available.
Causality*
;
Humans
;
Infant, Newborn*
;
Pneumothorax*
10.Hemothorax after subclavian vein catheterization.
Won Bae MOON ; Hae Kyu KIM ; Seong Wan BAIK ; Inn Se KIM ; Kyoo Sub CHUNG
The Korean Journal of Critical Care Medicine 1991;6(1):53-56
No abstract available.
Catheterization*
;
Catheters*
;
Hemothorax*
;
Subclavian Vein*