I experienced a case of a congenital intramural cyst of the uterine fundus. It was composed of a single layer of non-ciliated low cuboidal epithelium without associated with endometrial stroma and was found to be derived from the mesonephric duct. This case is presented with a brief review of the literature.
Epithelium ; Uterus* ; Wolffian Ducts

The pathogenesis and origin of vulvar cyst lined by a ciliated columnar epithelium is unknown. But it is suggested that origins of the epithelium of cyst are Mullerian or Wolffian duct or urogenital sinus, while heterotopia (sequestration and migration of tissue) or dysontogenesis (defective embryonic development) or prosoplasia (abnormal development resulting in a "higher state" of organization) or metaplasia have also been suggested. We experienced one case of Mullerian cyst of vulva. So we report above the case with a brief review of literature.
Epithelium ; Metaplasia ; Vulva* ; Wolffian Ducts

The pathogenesis and origin of vulvar cyst lined by a ciliated columnar epithelium is unknown. But it is suggested that origins of the epithelium of cyst are Mullerian or Wolffian duct or urogenital sinus, while heterotopia (sequestration and migration of tissue) or dysontogenesis (defective embryonic development) or prosoplasia (abnormal development resulting in a "higher state" of organization) or metaplasia have also been suggested. We experienced one case of Mullerian cyst of vulva. So we report above the case with a brief review of literature.
Epithelium ; Metaplasia ; Vulva* ; Wolffian Ducts

Posterior urethral valve is the most common obstructive abnormality in male children affecting both Kidneys and likely arise from maldevelopment of the mesonephric duct. We report a case of posterior urethral valve in 4 year old male child with brief review of literature.
Child ; Child, Preschool ; Humans ; Kidney ; Male ; Wolffian Ducts

This article reports a patient who suffered from Wolffian adnexal tumor.We also briefly elucidate the pathogenesis,clinicopathological features,diagnosis,differentiation,and treatment of Wolffian adnexal tumor,with an attempt to increase the awareness of the disease and reduce misdiagnosis.
Adenoma ; Adnexal Diseases ; Female ; Humans ; Immunohistochemistry ; Wolffian Ducts

The androgen insensitivity syndrome is a heterogeneous disorder with a wide spectrum of phenotypic abnormalities, ranging from complete female to ambiguous forms that more closely resembles males. Mutations of the androgen receptor gene are responsible for a variable degree of impaired androgen action. The complete androgen insensitivity syndrome is characterized by normal female external appearance in spite of the normal male karyotype 46XY with testes and normal testosterone production and metabolism. This is transmitted by X-linked recessive manner. Wolffian duct does not develop. However, m llerian development does not occur in presence of antim llerian hormone activity. Recently we experienced a case of complete androgen insenditirity syndrome. We reported a case with concerned literatures.
Androgen-Insensitivity Syndrome* ; Female ; Humans ; Karyotype ; Male ; Metabolism ; Receptors, Androgen ; Testis ; Testosterone ; Wolffian Ducts

Clear cell carcinoma of the bladder and urethra is very rare entity with its origin unclear. The typical location in the bladder neck and trogon tends to confirm that this neoplasm probably derives from a remnant of the mesonephric duct. But Mullerian remnants or metaplastic paraurethral elands may be the source of origin. We experienced a case of clear cell carcinoma of the bladder invading the posterior urethra occurring in a 68-year-old female treated by radical cystourethrectomy and ileal conduit diversion and 16 month later. we found a hard, fixed, palpable metastatic nodule in the left neck area. Herein we report a metastatic case of clear cell carcinoma or the bladder invading the posterior urethra with review of the literature.
Aged ; Female ; Humans ; Neck ; Urethra* ; Urinary Bladder* ; Urinary Diversion ; Wolffian Ducts

We report two cases of ectopic epididymal ducts and efferent ductules in the testicular appendices (TAs) of adult men with normally descended testes. In both cases, a sessile TA was incidentally found at the upper pole of the right testis during the scrotal hydrocelectomy. Microscopically, a few closely arranged tubules were detected within the TA. In the first case, the tubules were lined with a pseudostratified columnar epithelium with numerous, long microvilli, and were surrounded by a smooth muscle coat. In contrast, in the second case, the tubules had a wavy luminal surface, because ciliated columnar cells alternated with groups of cuboidal cells. In both cases, strong CD10 immunoreactivity was observed in the luminal border of the lining epithelium. Surgical pathologists should be aware of the presence of both ectopic epididymal ducts and efferent ductules that can occur in TAs, in order to avoid misinterpretation as transected, functional reproductive structures.
Adult ; Choristoma ; Epididymis ; Epithelium ; Female ; Humans ; Male ; Microvilli ; Muscle, Smooth ; Parovarian Cyst ; Phenobarbital ; Testis ; Wolffian Ducts

Herlyn-Werner-Wunderlich (HWW) syndrome is a rare, congenital genitourinary anomaly involving the Müllerian and Wolffian structures, and is characterized by the triad of uterine didelphys, obstructed hemivagina, and ipsilateral renal agenesis. It usually presents in adolescent girls in whom hematometrocolpos produces a pronounced mass effect and pain on the side of the obstructed hemivagina. Accurate diagnosis and surgical treatment can be delayed for several months or even years. Here, we report a case of a 12-year-old girl who presented to the emergency department with lower abdominal pain and mass that had lasted for 2 weeks. After the confirmation of HWW syndrome with magnetic resonance imaging, hysteroscopic septostomy was carried out as a definitive treatment. When we evaluate adolescent girls with lower abdominal pain and mass, we should consider the possibility of HWW syndrome.
Abdominal Pain ; Adolescent ; Child* ; Diagnosis ; Emergency Service, Hospital ; Female* ; Hematocolpos ; Humans ; Magnetic Resonance Imaging ; Mullerian Ducts ; Wolffian Ducts

The Complete testicular feminization syndrome is a hereditary syndrome characterized clinically by female phenotype with 46, XY karyotype and bilateral testes. There is a congenital insensitivity to androgens, transmitted by means of a maternal X-linked recessive gene responsible for the androgen intracellular receptor. Therefore, androgen induction of Wolffian duct development does not occur. However, anti-mullerian hormone activity is present and the individual does not have mullerian development. Principle of treatment is reinforced to live normal female life. This is a case report of testicular feminization syndrome with rudimentary salpinx with the brief review of literatures.
Androgen-Insensitivity Syndrome* ; Androgens ; Anti-Mullerian Hormone ; Fallopian Tubes* ; Female ; Genes, Recessive ; Humans ; Karyotype ; Male ; Phenotype ; Testis ; Wolffian Ducts