INTRODUCTION: Coronary artery disease (CAD) is one of the leading causes of death globally. Studies have shown association of CAD and its risk factors; however, data on association of these risk factors and severity of CAD as seen in angiography in our local setting are still limited.

OBJECTIVE: The aims of this study were to determine the clinical and angiographic profile of patients who underwent coronary angiography, to correlate cardiovascular risk factors to their angiographic findings, and to compare the trend of risk factors and angiography findings between decades.

METHODS: This is a retrospective observational study of patients aged 18 years or older, of either sex, who underwent coronary angiography at a tertiary hospital from 2001 to 2019. Pertinent risk factors were correlated with angiography findings to determine predictors for significant CAD.

RESULTS: The mean age of the patients was 58.6 years. There were more males (66%) than females. The risk factors for the likelihood of significant CAD are older age (4.98% more for every year increase in age), male sex (2.63 times), and diabetes mellitus (47.64%). The majority of the patients had right dominant circulation, and significant lesions were more commonly seen in the left anterior descending artery. There were statistically significant more patients with hypertension, diabetes, and obesity in the present decade compared with the past.

CONCLUSION: Increased age, male sex, and diabetes are associated with significant CAD in the local setting. Diabetes must be aggressively controlled early to prevent the development of significant CAD.

KEYWORDS: coronary artery disease, risk factors, profile, coronary angiography

Introduction: The rapidly growing number of percutaneous coronary interventions has led to a considerable improvement in the outcome of patients with acute coronary syndromes, yet concurrently exposing patients to enormous volumes of contrast media with the inherent risk of renal function impairment. Objective: To determine the incidence of contrast induced nephropathy of patients admitted at University of Santo Tomas Hospital (USTH) who underwent coronary angiography with or without Percutaneous Transluminal Coronary Angioplasty (PTCA). Methodology: This is a retrospective, descriptive study including patients aged 18 years and above, of any gender, admitted at the USTH from January 1, 2016 to December 31, 2016, who underwent coronary angiography with or without PTCA with baseline and follow up creatinine levels 48-72 hours after the procedure. Data were retrieved by review of medical records of these patients. Results: Three out of 78 patients (3.8%) had elevated creatinine but all three patients also underwent major surgery within 48 hours after coronary angiography which could explain the renal impairment. Conclusion Although contrast induced nephropathy was described as the third most common cause of new Acute Kidney Injury in hospitalized patients, it was accordingly nil among those who underwent coronary angiography at USTH from January to December 2016. Benefi ts and risks of undergoing coronary angiography should always be weighed individually. Risk stratifi cation scores should only serve as a guide in managing patients and proper preventive measures should be applied.
Coronary Angiography ; ErbB Receptors