1.Surgical results of esophageal cancer.
Ki Bong KIM ; Cheol Hyun CHUNG ; Jeong Sang LEE ; Sook Whan SUNG ; Joo Hyun KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(12):1530-1536
No abstract available.
Esophageal Neoplasms*
2.Multicystic mesothelioma of the peritoneum: case report.
Jeong Ho KWAK ; Eung Whan CHOE ; Hye Young KIM ; Kyung Ho KIM
Journal of the Korean Radiological Society 1993;29(2):283-286
Cystic mesothelioma of the peritoneum is a rare benign neoplasm that occurs predominantly in young to middle-aged women and tends to recur locally. Pelvic viscera is the most common predilection site of cystic mesothelioma. Authors report a case of multicystic mesothelioma of the pelvic pelvic peritoneum. The pelvic ultrasonography showed a large, confluent, and thin-walled multilocular cystic mass occupying the pelvic cavity and lower abdomen. The cystic mass was flattened and elongated. Each cyst of variable size was separated by thin septa and filled with translucent fluid. Cystic mesothelioma should be included in the differential diagnosis of the cystic peritoneal masses, especially in reproductive-aged women.
Abdomen
;
Diagnosis, Differential
;
Female
;
Humans
;
Mesothelioma*
;
Mesothelioma, Cystic
;
Peritoneum*
;
Ultrasonography
;
Viscera
3.Study on the experimental single lung transplantation in the Mongrel dogs(I).
Joo Hyun KIM ; Hyun SONG ; Kyeh Hyeon PARK ; Sang Rock CHO ; Jeong Sang LEE ; Bong KIM ; Sook Whan SUNG ; Chong Whan KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(6):533-540
No abstract available.
Lung Transplantation*
;
Lung*
4.A Pemphigus Vulgaris with IgG1 and IgG4 Subclass Autoantibodies.
Suk Woo LEE ; Jeong Ki RHE ; Dong HOUH ; Young Jin OH ; Young Whan KIM ; Won HOUH
Annals of Dermatology 1990;2(1):35-38
The distribution of pemphigus subclass autoantibodies in a patient with pemphigus vulgaris (PV) has been investigated by semiquantitative indirect immunofluorescence (IIF), using the HP series monoclonal antibodies specific for four human IgG subclasses on human foreskins. IgG1 and IgG4 intercellular substance-specific autoantibodies were detected in the serum of the patient, whereas IgG2 and IgG3 autoantibodies were absent. In addition to foreskins, human tonsillar epithelia were used as substrates of IIF for detecting the PV autoantibodies and it was one of satisfactory substitutes for monkey esophagus.
Antibodies, Monoclonal
;
Autoantibodies*
;
Esophagus
;
Fluorescent Antibody Technique, Indirect
;
Foreskin
;
Haplorhini
;
Humans
;
Immunoglobulin G*
;
Pemphigus*
5.Computed tomographic findings of maxillary sinus cancer.
Jeong Whan LIM ; Hong Soo KIM ; Jin Ok CHOI ; Doo Sung JEON ; Hak Song RHEE
Journal of the Korean Radiological Society 1991;27(6):778-783
No abstract available.
Maxillary Sinus Neoplasms*
;
Maxillary Sinus*
6.A study on the fine structure of Clonorchis sinensis, a liver fluke III.The prostate gland.
Kye Heon JEONG ; Han Jong RIM ; Chang Whan KIM
The Korean Journal of Parasitology 1980;18(1):93-97
A study on the ultrastructures of the prostate gland of Clonorchis sinensis was conducted. The presence of the prostate gland in this fluke has not been known up to present time. Authors observed the ejaculatory duct epithelium including its surrounding parenchyma and found the prostate gland with the help of the electron microscope. The prostate gland was consisted of numerous unicellular glands grouped around the ejaculatory duct. The individual cell was lobulated, tapering in the direction of the ejaculatory duct. The secreting ducts of the gland penetrated into the ejaculatory duct through the muscular layer and the basement membrane, and finally opened to the lumen of the ejaculatory duct. The secreting duct had single layered microtubules along the inner wall of the duct. The secretory bodies produced by the prostate gland seemed to be moved to the lumen of the ejaculatory duct through the secreting duct. The prostate gland of this fluke was less developed than that of Fasciola hepatica but the basic structures were quite similar. There were well-developed lamellae in the epithelia of all ducts concerning passage of spermatozoa from the testes to the male genital opening.
parasitology-helminth-trematoda
;
Clonorchis sinensis
;
electronmicroscopy
;
prostatic gland
;
rat
;
liver
7.Relationship between traumatic spinal canal stenosis and neurologic deficits in thoracic and lumbar burst fractures.
Won Sik CHOY ; Whan Jeong KIM ; Kwang Won LEE ; Hyun Dae SHIN ; Yong Su PARK
The Journal of the Korean Orthopaedic Association 1993;28(1):123-129
No abstract available.
Constriction, Pathologic*
;
Neurologic Manifestations*
;
Spinal Canal*
8.Magnetic Resonance Imaging on Postoperative Pain Syndrome.
June Kyu LEE ; Jae Sung AHN ; Je Taek JEONG ; Soon Tae KWON ; Whan Jeung KIM
The Journal of the Korean Orthopaedic Association 1999;34(1):127-133
PURPOSE: To determine the accuracy of MRI on postoperative pain syndrome (POPS), including early complications such as hematoma or infection. MATERIALS AND METHODS: Of the 54 patients with the POPS, we analyzed pre-operative MRI findings compared with operative findings on 39 patients, excluding nonunion, instability, metal failure and pseudarthrosis, who underwent an operation for POPS from December 1994 to June 1997. There were 25 men (64.1%) and 14 women (35.9%), aged from 16 to 68 years (average 44.5 years). They were divided into 5 subgroups and calculated for sensitivity, specificity and positive predictability. RESULTS: MRI accuracy in recurred disc was 84%, scar adhesion, recurred or developed stenosis, infection and hematoma was 100% for each overall accuracy of MRI was 93%. Average interval of reoperation in POPS was 3.2 years. In 21 cases (53.8%), symptoms persisted without pain-free interval after first operation. CONCLUSIONS: Early complications, including hematoma and infection, are easily detected with MRI. Especially if patient complains of severe leg pain or neurologic deficit, MRI is a good diagnostic tool. MRI is a useful method for evaluation of most cases of POPS, but it is limited in evaluating recurred disc or scar adhesion only in T1, T2 weighted image. Therefore, Gd-DTPA enhancement is necessary for an accurate diagnosis.
Cicatrix
;
Constriction, Pathologic
;
Diagnosis
;
Female
;
Gadolinium DTPA
;
Hematoma
;
Humans
;
Leg
;
Magnetic Resonance Imaging*
;
Male
;
Neurologic Manifestations
;
Pain, Postoperative*
;
Pseudarthrosis
;
Reoperation
;
Sensitivity and Specificity
9.Pyogenic Arthritis in Renal Transplant Recipients.
Jung Man KIM ; Chang Whan HAN ; Jeong Tae SEO ; Byung Kee BANG ; Yong Bok KOH
The Journal of the Korean Orthopaedic Association 1997;32(3):689-696
Acute pyogenic arthritis in renal transplant patient is one of the serious problem resulting in significant morbidity and mortality. The purpose of this paper is to analyze seven patients in whom acute pyogenic arthritis developed following renal transplantation. Pyogenic arthritis developed in seven (0.7%) out of 958 renal transplant patients whose transplanted kidney functioned well for more than two years. The age of the patients ranged from 37 to 65 years with a mean of 48 years. All patients were male. Pyogenic arthritis developed between the period of one and 12 years (mean: 4.5+/-4.2 years) following transplantation. Causative organisms were Staphylococcus aureus (three), E. coli (two), Salmonella (one) and Acinetobacter bananii (one). Involved joints were four knees, one hip, one elbow and one finger. Two patients improved on a conservative regimen of bed rest and antibiotics and five patients required open drainage. However, pyogenic arthritis recurred in three years, four years and seven years after renal transplant in one patient. Looking at the probable risk factors of age, sex, immunosuppresants, diabetics and acute graft rejection, diabetics and older age (over 40 years old) are highly associated with post renal transplant pyogenic arthritis.
Acinetobacter
;
Anti-Bacterial Agents
;
Arthritis*
;
Bed Rest
;
Drainage
;
Elbow
;
Fingers
;
Graft Rejection
;
Hip
;
Humans
;
Joints
;
Kidney
;
Kidney Transplantation
;
Knee
;
Male
;
Mortality
;
Risk Factors
;
Salmonella
;
Staphylococcus aureus
;
Transplantation*
10.Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity.
Ho Shik KIM ; Seong Yun JEONG ; Jeong Hwa LEE ; Boe Eun KIM ; Jin Woo KIM ; Seong Whan JEONG ; In Kyung KIM
Experimental & Molecular Medicine 2000;32(4):197-203
3-Deazaadenosine (DZA), one of the potent inhibitors of S-adenosylhomocysteine hydrolase, is known to possess several biological properties including an induction of apoptosis. To evaluate a possibility that DZA may be utilized for the treatment of human leukemia, we studied molecular events of cell death induced by DZA in human leukemia HL-60 and U-937 cells. DZA induced a specific cleavage of poly ADP-ribose polymerase (PARP) and an activation of the cysteine protease caspase-3/CPP32 which is known to cleave PARP. DZA-mediated nuclear DNA-fragmentation was completely blocked in the presence of a universal inhibitor of caspases (z-VAD-fmk) or the specific inhibitor of caspase-3 (z-DEVD-fmk) unlike of cycloheximide (CHX). DNA fragmentation was preceded by the lowering of c-myc mRNA in the DZA treated cells. In addition, DZA-induced apoptosis was blocked by pretreatment with adenosine transporter inhibitors such as nitrobenzylthioinosine (NBTI) and dipyridamole (DPD). Taken together, these results demonstrate that DZA-induced apoptosis initiated through an active transport of DZA into human leukemia cells, is dependent on the caspase-3-like activity without de novo synthesis of proteins and possibly involves c-myc down-regulation.
Adenosine/metabolism
;
*Apoptosis
;
Biological Transport, Active
;
Carrier Proteins/metabolism
;
Caspases/*metabolism
;
Down-Regulation
;
Enzyme Activation
;
Genes, myc
;
HL-60 Cells
;
Human
;
Leukemia, Promyelocytic, Acute/*drug therapy
;
Thioinosine/*analogs & derivatives/pharmacology
;
Transcription Factors/genetics
;
Tubercidin/*pharmacology
;
U937 Cells