We studied ten patients who received autogenous dermis-fat implantation in anophthalmic sockets during the last one year. Eight cases were performed after primary enucleation and two cases were used as a secondary implant for socket problems. This technique preserves good fornices and supplies movable implants with little chance of fat atrophy or extrusion.
Atrophy ; Equipment and Supplies ; Humans ; Transplants*

No abstract available.
Body Weight* ; Diet* ; Exercise Therapy* ; Humans

PURPOSE: To evaluate the effect of mitomycin C (MMC) on osteotomy site as an adjunctive therapeutic agent during dacryocystorhinostomy, the effect of MMC on cultured rabbit osteoblasts was tested. METHODS: Cultured osteoblasts which was obtained from the iliac crest of rabbits, were treated with MMC (0.2 mg/ml) for 5 or 30 minutes, washed and changed with fresh osteogenic media (Opti-MEM), and then cultured for 24 hours. To observe the effect of MMC dose dependency on cultured osteoblasts, four different concentrations of MMC (0.2 mg/ml, 0.02 mg/ml, 0.002 mg/ml, 0.0002 mg/ml) were applied into the cells and cultured for 24 hours. The effect of fibroblast growth factor (FGF) and transforming growth factor-beta(TGF-beta) on the MMC-treated cells was evaluated. In control group, osteoblasts were cultured in osteogenic media without exposure of MMC for 24 hours. Cell viability was measured using trypan blue staining method. RESULTS: As compared with control group, the growth of osteoblasts was inhibited by MMC (0.2 mg/ml) treatment, 30-minute treatment group demonstrated marked suppression twice as much as 5-minute treatment group. Growth rate of 0.2 mg/ml MMC-treated cells was highly suppressed to 7.7% of control and 0.02 mg/ml MMC-treated cells was inhibited to 15.4% in number. Growth rate of 0.002 mg/ml, 0.0002 mg/ml MMC-treated cells was diminished to 53.8%, 84.6% in number, respectively. Both growth factors had promotive effect on the growth of osteoblasts in 0.002 mg/ml MMC-treated cells, especially in TGF-beta. CONCLUSION: Osteoblasts which were treated for longer time and with higher concentration of MMC showed more severe suppression in growth rate. These results suggest that MMC could have some therapeutic effect on osteotomy site of dacryocystorhinostomy.
Cell Survival ; Dacryocystorhinostomy ; Fibroblast Growth Factors ; Intercellular Signaling Peptides and Proteins ; Mitomycin* ; Osteoblasts* ; Osteotomy ; Rabbits ; Transforming Growth Factor beta ; Trypan Blue

PURPOSE: To evaluate the success rate of conventional skin dacryocystorhinostomy(DCR), the success rate and postoperative complications were evaluated after the follow-up period of 6~72 months(average 16.7 months), and compared with those of our previous reports on endonasal DCR, at postoperative 6 months(PO6M) and 12 months(PO12M). METHODS: skin DCR was performed in 76 patients, 89 eyes between July 1993 and June 2000 at the Department of Ophthalmology, Yeungnam University College of Medicine. RESULTS: Primary success rate of skin DCR was 93.3%, and the final success rate after revision of mucosal ostium revealed 96.6%. Postoperative complications included 7 cases of silicone tube protrusion and 4 cases of mucosal ostium obstruction. CONCLUSIONS: Primary success rate of skin DCR was 93.3%, and those of endonasal DCR were 92.3%(PO6M) and 89.8%(PO12M). The final success rate of skin DCR was 96.6%, and those of endonasal DCR were 98.4%(PO6M) and 99.2%(PO12M).
Follow-Up Studies ; Humans ; Ophthalmology ; Postoperative Complications ; Silicones ; Skin

PURPOSE: To evaluate the surgical result of lacrimal surgery with total removal of the nasal mucosal flap. METHODS: Lacrimal surgery was performed in 30 eyes of 26 patients, by external approach without the nasal mucosal flap from February 2001 to August 2002. The surgical method was similar to conventional dacryocystorhinostomy, but the nasal mucosa of the osteotomy site was removed with a No.11 Bard-Parker blade and Westcott scissors. After insertion of a silicone tube, the anterior flap of the lacrimal sac was sutured to the soft tissues around the osteotomy site. Surgical efficacy was evaluated after a follow-up period of 7 22 months (average, 11.5 months). RESULTS: The primary success rate was 96.7% (29/30 eyes). We performed revision of mucosa ostium in the one failed eye, thereby raising the final success rate to 100%. The size of mucosa ostium was 0.7 3.0 mm (average 1.17 mm). CONCLUSIONS: Satisfactory surgical results were obtained without anastomosis of the lacrimal sac or the nasal mucosa during external approach, lacrimal surgery. We suggest that this method is a good surgical procedure in external approach, lacrimal surgery.
Dacryocystorhinostomy ; Follow-Up Studies ; Humans ; Mucous Membrane ; Nasal Mucosa ; Osteotomy ; Silicones

Secondary ischemic necrosis of femoral head due to loss of blood supply following to femoral neck fracture is well known. The regional distribution of bone.seeking radiopharmaceuricals in the skeleton can depend on a number of facto rs, but bone blood flow is a major physiological determinant of regional skeletal uptake of Tc-99m polyphosphate and bone imaging may thus be used for the evaluation of vascularity of the femoral head. The authors made a comparative study of scintigraphic findings and operative findings of 28 cases of femoral neck fracture treated at Kyung Hee University Hospital from April ′80 to May ′84. The results were as follows: 1. In 16 cases of proven avscular necrosis of femoral head, scintigraphy showed absent or decreased activity in 14 cases (87.5%), while radiography showed increased density in 10 cases (62.5%). 2. In 12 cases of proven vital femoral head, scintigraphy showed increased activity in 9 cases (75%) and radiography showed decreased density in 9 cases (75%). 3. 99mTc-MDP scintigraphy was an excellent and useful method for assessing bone vitality of femoral head.
Femoral Neck Fractures ; Femur Head Necrosis ; Femur Neck ; Head ; Methods ; Necrosis ; Radiography ; Radionuclide Imaging ; Skeleton ; Technetium Tc 99m Medronate

No abstract available.
Barium* ; Child* ; Humans ; Intussusception* ; Ultrasonography*

PURPOSE: To evaluate the effect of mitomycin-C (MMC) on osteotomy site as an adjunctive therapy for dacryocystorhinostomy, the effect of MMC on cultured human osteoblasts was tested. METHODS: Cultured osteoblasts which was obtained from the human iliac crest, were treated with four different concentrations of MMC (0 mg/ml, 0.2 mg/ml, 0.02 mg/ml, 0.002 mg/ml) and cultured for 24hours. To observe the effect of exposed time dependency, cells were treated with MMC during 5, 30minutes, and 24hours and washed and changed with fresh osteogenic media, and then cultured for 24 hours. The effect of fibroblast growth factor (FGF) and transforming growth factor-beta(TGF-beta) on the MMC-treated cells was evaluated. Cell viability was measured using trypan blue staining method and MTT assay. RESULTS: As compared with control group, the lowest growth rate of osteoblasts was 6.8% in 0.2 mg/ml MMC-treated cells. There were no significant differences in the growth rate between 5 minutes and 30 minutes MMC treatment groups, but in case of 24 hours treatment group with MMC (0.2 mg/ml) the growth rate was suppressed to 77.5% of control group with statistical significance. Both growth factors had promotive effect on the growth of in 0.02 mg/ml MMC-treated osteoblasts, but not in 0.2 mg/ml MMC-treated cells. CONCLUSIONS: Osteoblasts which were treated for longer time and with higher concentration of MMC showed more suppression in growth rate. These results suggest that intraoperative application of MMC during dacryocystirhinostomy could have a positive effect of mucosal ostium with suppression of osteoblasts proliferation.
Cell Survival ; Dacryocystorhinostomy ; Fibroblast Growth Factors ; Humans* ; Intercellular Signaling Peptides and Proteins ; Mitomycin* ; Osteoblasts* ; Osteotomy ; Trypan Blue

Radionuclide scrotal scintigraphy with 99m Tc-pertechnetate is an easy, well established, sueful and readilyavailable technique for evaluation of acute scrotum. We studied 41 cases of radionuclide scrotal scintigraphy andthe results were as follows; 1. The over all diagnostic accuracy of scrotal scintigraphy waas 93%(38/41 cases). 2.Scrotal scintigraphy was very useful and accurate in differential diagnosis of epididymo-orchitis and testiculartorsion in patient with acute scrotal pain and swelling, while there was some limitation in differential diagnosisof hematoma from acute epididymo-orchitis or torsion. 3. scintigraphy of epididymoorchitis showed increasedperfusion and radiocativity in the epididymis and/or testis and its diagnostic accuracy was 90%(19/21 cases) 4.Acute testicular torsion showed normal flow in perfusion and cold defect occupying affected testis in staticimage, while missed torsion showed slightly increased flow in perfusion image and cold defect surrounded by anuniform rim of hyperactivity (halo sign). Diagnostic accuracy of testicular torsion was 86%(6/7 cases).
Diagnosis, Differential ; Epididymis ; Hematoma ; Humans ; Male ; Perfusion ; Radionuclide Imaging ; Scrotum ; Spermatic Cord Torsion ; Testis

The authors have studied the findings of radionuclear scanning, inferior vena cavography and ultrasonographyin 2 cases of Budd-chiari Sundrome experienced diffuse inhomogeneous uptake throughout enlarged liver without colddefects. Slightly increased activity in the central portion of liver in case I and markedly increased activity inthe caudate lobe in case II were observed. In inferior vena cavography, the dilated hepatic veins formingintrahepatic collaterals were seen in enlarged caudate lobe. Marked stenosis of I.V.C. at the level of confluenceto right atrium, intraluminal thrombosis of I.V.C., partial obstruction of hepatic veins by thrombi at theconfluent portion and systemic collaterals were noted in case I. In case II, abrupt conical obstruction of I.V.C.at the orgin of hepatic segment, which is consistent with membrane or web. was seen. Prominent systemiccollaterals were developed through the serpinginous margedly dilated azygos and hemiazygos veins, and splenorenalshunt. In ultrasonography, diffuse narrowing and obstruction of hepatic veins at eh confluent level by echogenicnodules were seen in 2 cases. Prominent intrahepatic venous collaterals were observed in case II.
Budd-Chiari Syndrome ; Constriction, Pathologic ; Heart Atria ; Hepatic Veins ; Hepatomegaly ; Liver ; Membranes ; Thrombosis ; Ultrasonography ; Veins