No abstract available.
Hair ; Survival Rate ; Transplants

No abstract available.

No abstract available.
Adolescent* ; Humans ; Male* ; Psoriasis*

Basal cell carcinoma is a malignant tumor of the skin that is believed to arise from the hair follicle. In addition to the typical lesion just described, several clinical and histological varieties are recognized. Polypoid basal cell carcinoma, a new distinctive form, has been described as verrucoid, fungating or polypoid mass with stalk and histologically distinguished by restriction of the tumor aggregation to the mass from the other variants. We report a case of basal cell carcinoma of right knee that was pedunculated and had stalk with lobulated surface.
Carcinoma, Basal Cell* ; Hair Follicle ; Knee ; Skin

Granular cell tumors are uncommon benign tumors occurring most commonly on the tongue, skin and subcutaneous tissue. They are most often seen as a solitary nodule in adults. Multiple lesions are very rare, particularly in children. We report a case of multiple granular cell tumors in a 13-year-old boy on his left arm which was presented as firm, flesh-colored, match-head to pea-sized, tender nodules for 6 months. Histologically, the tumors are nonencapsulated nodules, composed of large, polyhedral cells with an abundant eosinophilic granular cytoplasm. By immunohistochemistry, the granular cells are strongly positive for S-100 protein.
Adolescent ; Adult ; Arm ; Child ; Cytoplasm ; Eosinophils ; Granular Cell Tumor* ; Humans ; Immunohistochemistry ; Male ; S100 Proteins ; Skin ; Subcutaneous Tissue ; Tongue

No abstract available.
Mycoplasma pneumoniae* ; Mycoplasma* ; Pneumonia* ; Pneumonia, Mycoplasma*

We report two cases of proliferating trichilemmal cyst in a 61-ear-old woman and a 44-year-old woman who had a solitary tumor, on the left temporal area of the scalp and right flank, respectively. Histologically, the tumors were localized in the dermis and corisised of multilobulated cysts. The cyst walls were composed of liquamous epithelium showing trichilemmhl keratinization. Some of the cells had clear cytoplasm and were positive on PAS staining. Individiial cell keratinization, mild nuclear atypia were also found in the cyst walls. For the treatment, surgical excision was performed with sufficiert margin.
Adult ; Cytoplasm ; Dermis ; Epithelium ; Female ; Humans ; Scalp

BACKGROUND: In recent years alternative medicine such as herbal medicines has been attractive and useful in dermatologic therapy. But there is little scientific information about its therapeutic effects and potential side effects. OBJECTIVE: We performed this study to assess the whitening effect of the root of Ma Huang. METHODS: Thirty subjects were tanned by UVB irradiation on their abdomen and 4 pigmented patches in square were obtained. In a single-blind fashion, participants applied the root extract of Ma Huang to two pigmented patches and vehicle to another patch on the abdomen twice a day, and applied nothing to the other patch for 8 weeks. Participants were followed up every week and checked on a melanin index with a mexameter. We also checked the last clinical improvement 8 weeks after the application of the root extract of Ma Huang. RESULTS: MED of the middle back was 73+/-24.66cmJ/cm2. Melanin index of the abdomen was 473.2+/-16.27. Eight weeks after application, the mean change percent of the melanin index of the right upper and lower squares applied with the root extract of Ma Huang were +0.02%(p=0.96) and -0.16%(p=0.76). The mean change percent of the left upper square applied with vehicle was -0.08%(p=0.89). The mean change percent of the left lower square untreated was +0.20(p=0.65). One-way layout ANOVA showed no difference among four squares. Clinical evaluation of improvement did not satisfy: no change 36%; slight improvement 53%; moderate improvement 9%; marked improvement 2%. CONCLUSIONS: The root of Ma Huang did not show the whitening effect on the UVB-induced pigmentation checked by the mexameter but showed slight improvement in visual assessment.
Abdomen ; Complementary Therapies ; Ephedra sinica* ; Melanins ; Pigmentation ; Triacetoneamine-N-Oxyl

BACKGROUND: Skin smoothness in aging skin, in combination of intrinsic aging and photoaging, is of ever-increasing interest which leads to the development of various wrinkle diminuation products including those containing herbal medicines. OBJECTIVES: The purpose of this study was to assess the efficacy of cosmetics containing roots of Ephedra sinica and Betula platyphylla var. japonica on reducing skin furrows. METHOD: Creams containing Ephedra sinica's root and Betula platyphylla var. japonica were applied to forearms of 30 healthy subjects in 2 age groups for 8 weeks and 4 weeks, respectively while silicone skin replicas were taken from medial and lateral sides of the forearm every 4 weeks of the study starting from the week 0. Then the changes of the skin furrows were analyzed with skin visiometer. RESULTS: 1. At week 8, a significant reduction of average roughness and maximum roughness were observed in volunteers younger than age 50 on their Ephedra sinica's root-treated side compared with the placebo-treated side (p<0.05). 2. No statistically significant changes were observed with both Ephedra sinica's root and Betula platyphylla var. japonica in the group of age over 50. 3. Comparison of the changes between treatment groups of both Ephedra sinica's root and Betula platyphylla var. japonica at any assessment time did not show statistically significant differences between the medial and lateral side of forearm, while the treatment group of Ephedra sinica's root showed statistically significant differences between the young and old at week 8 (p<0.05). CONCLUSIONS: The treatment of Ephedra sinica's root seems to be partially effective in improving skin furrows in youth. To our knowledge, this study is the first trial to evaluate the efficacy of both Ephedra sinica's root and Betula platyphylla var. japonica on decreasing wrinkle in the world.
Adolescent ; Aging ; Betula* ; Ephedra sinica* ; Ephedra* ; Forearm ; Humans ; Silicones ; Skin* ; Volunteers

BACKGROUND: The efficiency of lipid extraction by different kinds of solvents from stratum corneum may vary. OBJECTIVE: To assess the efficiency of lipid extraction by several solvents from the stratum corneum, the total lipids weights were measured by an electronic microbalance, and lipids compositions of a stratum corneum were analyzed by thin layer chromatography(TLC) after pretreatment of several solvents, respectively. METHODS: Stratum corneums separated fro circumcised prepuce were pretreated with acetone, petroleum ether, or distillecl water for 10 minutes. Lipids of stratum corneum were extracted with methanol chlorofonn-H,O mixture(4: 2: 1.6, v/v, Bligh Dyer solvent). Lipids weights were weighed, and the ratio of lipid weight and wet weight of stratum corneum were measured. TLC was performed and lipids compositions were quantitated by photodensitometer. Lipids extraction in viva was performed on both forearms. After two times stripping with sellotape, lipids were extrected with the solvents using cup method. These were dried and lipids weights were weighed. RESULTS: The efficiency of lipid extraction from the stratum corneum of circumcised prepuce were acetone, petroleum e1 her, and distilled water in decreasing order. All groups were similar in the compositions of the stratum corneum lipids except for those of cholesterol esters and sphingolipids. The efficiency of lipid extraction from in vivo skin were ranked in order from petroleurn ether, acetone, down to distilled water. The efficiency of lipid extraction of petroleum ether and acetone were higher than that of distilled water. CONCLUSION: The efficiency of lipid extraction is influenced by the kinds of solvents as well as the materials and the methods of extraction.
Acetone ; Cholesterol Esters ; Ether ; Forearm ; Methanol ; Petroleum ; Skin ; Solvents* ; Sphingolipids ; Water ; Weights and Measures