Objective To explore effect of psychological intervention on negative automatic thoughts,self acceptance and social support for patients with type 2 diabetic cataract.Methods Patients with diagnosed type 2 diabetic cataract(n=105)were divided into the research group(56 cases)and the control group(49 cases).The centrol group received routine treatment.The research group was given psychological and behavioral intervention based on routine treatment.They underwent evaluation by negative automatic thoughts questionnaire (ATQ),self-acceptance questionnaire(SAQ)and social support rate scale(SSRS)before intervention and in the 2th and 6th weeks after intervention.The results were subsequendy analyzed. Results ATQ score of the research group in the 2th and 6th weeks were lower than that of the control group(P＜0.05).ATQ score,total SAQ score,score of SA and SD factors,total SSRS score and score of objective support,subjective support and utilization of support were all lower than those before intervention from the 2th week in the research group.While these happened in the control group only in the 6th week(P＜0.05).Total SAQ score and score of SA and SD factor were lower than those of the control group(P＜0.05).Total SSRS score and score of objective support,subjective support and utilization of support were lower than those of the control group(P＜0.05).Relative analysis showed total score of social support and its factors was negatively related with ATQ score,but was positively related with SAQ score and score of SA and SD factors(P＜0.05).Conclusions Psychological and behavioral intervention could reduce the negative automatic thoughts,allevinte self acceptance and increase social support degree for patients with type 2 diabetic cataract.

It has recently been demonstrated that anti-angiogenesis drugs targeting every possible aspect of tumor angiogenesis effectively inhibit the growth, invasion and metastasis of breast cancer with low sideeffects and drug resistance. These types of anti-angiogenesis drugs have become a hotspot in the field of breast cancer research.

Object To provide a basis for the identification and development of Echinacea angustifolia DC Methods Pharmacognostical studies were carried out by phytotomy, macroscopic and microscopic analysis Results Detailed description of its pharmacognostical characteristics were accomplished and described Conclusion The results can be used for quality standardization of commercial product of E angustifolia

Objective To summarize the experience of diagnosis and management of regional portal hypertension. Methods The clinical manifestations, diagnostic methods and therapeutic modalities of 16 cases of regional portal hypertension were analyzed retrospectively. Results Among 16 patients with ~regional portal hypertension, 12 cases resulted from pancreatic diseases, and 4 cases were complicated with non-pancreatic diseases. The main clinical findings were splenomegaly in 16(100%), abdominal pain ~in 10(63%) , gastrointestinal bleeding in 7(44%) and abdominal masses in 3(19%). All had normal liver function test. The main diagnostic methods were ultrasonography(US), computerized tomography (CT) and endoscopy. Splenic vein thrombosis could be detected by color Doppler ultrasonography (7/7). ~Enhanced CT could demonstrate enlarged and tortuous short gastric veins, gastroepiploic veins, and ~coll- ~ateral vessels around splenic hilum(16/16). Isolated gastric varices (4/5) were revealed mainly by ~gastro- ~scopy . Splenectomy was effective for controlling gastrointestinal bleeding, and its complication of portal vein thrombosis occurred in 1 case. Conclusions It is not difficult to diagnose regional portal ~hyper- ~tension based on findings of US and CT, together with special clinical characteristics. Therapeutic options should be ~individualized according to underlying diseases, however, splenectomy should be performed in the ~patients with gastrointestinal bleeding.

Objective To compare the histological effects of 1.44-?m and 1.06-?m pulse Nd:YAG laser radiation on stomach wall tissues in dogs. Methods Five beagle dogs were enrolled in this study to received 1.44-?m(experiment group) and 1.06-?m(self-control group) pulse Nd:YAG laser radiation at the posterior wall of the stomach.Totally 19 dosage of radiation was used including a 0-mJ radiation.The dosage of every single pulse was 200,500,or 800 mJ,and the amount of the pulses was 1,5,10,20,40 or 80.The experiment was repeated for 5 times.Afterwards,the injured tissues was obtained and observed under a light microscope and the photomicrograph was taken at the meantime.Results In experimental groups,the widest and photoevaporated zone and coagulation zone were(1863.8?225.0) ?m and(885.1?82.9) ?m,and the deepest photoevaporated zone and coagulation zone were(1787.4?93.7) ?m and(1327.8?86.3) ?m,respectively;which were significantly higher than those in the control [widest and photoevaporated zone and coagulation zone:(576.8?30.8) ?m and(1275.8?140.1) ?m,t=12.672,P=0.000 and t=-5.366,P=0.001;deepest photoevaporated zone and coagulation zone:(105.0?16.3) ?m and(994.8?130.0) ?m,t=39.539,P=0.000 and t=4.773,P=0.002;respectively].Conclusions 1.44-?m Nd:YAG laser is suitable for vaporization and coagulation in stomach surgery.It shows higher ability in vaporization but lower ability of coagulation than 1.06-?m pulse Nd:YAG laser radiation,which,however does not affect the outcomes of wound cleansing and hemostasis.

OBJECTIVE To analyze the antibiotics usage in perioperative patients of oral surgery in our hospital.METHODS Adopted retrospective review,365 oral surgery inpatients with operation were investigated on medication,course of treatment,wound healing and so on.RESULTS The utilization of antibacterials accounted for 100%.Nitramisole,aminoglycosides,Cephalosporin and penicillins were the main kinds.Single use accounted for 18.63%(66 cases),the bigeminy for 43.29%(158 cases),the trigeminy for 27.12%(99 cases),the utilization with four or more drugs were 18.63%(40 cases);the average of treatment course was 8 days.CONCLUSIONS To strengthen the management of antibacterials,more education of the principle medicine,usage are helful for reducing surgical site infection.

Background and purpose:Hereditary nonpolyposis colorectal cancer(HNPCC) which related to inheritance is an autosomal dominant inheritance.There are many screening standards differing presently from country to country.The Amsterdam standard is internationally recognized.These screening standards are just based on family history and clinical manifestations which can not reflect the essence of the disease.At present,the golden standard for screening HNPCC is mismatch repair genes detection that is in the experimental stage.The purpose of this study was to investigate the expression of mismatch repair genes hMSH2 and hMLH1 in HNPCC and their clinicopathological signif icance,and to fi nd a simple,fast and economic method for screening HNPCC.Methods:Immunohistochemical staining was used to detect the expression of hMSH2 and hMLH1 in 20 cases with HNPCC(Group A),20 cases with ordinary hereditary colorectal cancer(Group B),20 cases with sporadic colorectal cancer(Group C),and 20 cases with colorectal polyps(Group D).Results:The expression rates of hMSH2 and hMLH1 in Group A,B,C and D were 35%(7/20),70%(14/20),95%(19/20) and 100%(20/20) respectively,which illustrated that the probability of HNPCC and the negative expression of hMSH2 and hMLH1 was reduced from Group A to Group D.There were signifi cant differences among these groups(P0.05).Conclusion:The negative expression of hMSH2 and hMLH1 was signifi cantly correlated with HNPCC and location and differentiation of colon carcinoma.Immunohistochemical staining may be useful for screening HNPCC.

The lymphatic metastasis affects prognosis and survival of colorectal cancer seriously,and lymphangiogenesis plays an important role in the lymphatic metastasis. Many factors such as COX-2 and MMP-7 which are found in many researches recently can promote the expression of VEGF-C which can promote the lym-phangiogenesis by connecting with its receptor and activating the relevant signal pathway. At present,as these related factors of lymphangiogenesis are found in colorectal cancer,the process of lymphangiogenesis in colorec-tal cancer becomes more clear,but the exact mechanism of these factors needs to be researched in future.

Objective To evaluate the effects of nicotine or electric vagal stimulation on injury to transplanted lungs in rats.Methods Twenty-four male Wistar rats with transplanted lung,weighing 250-300 g,were randomly divided into 3 groups (n =8 each) using a random number table:control group (group C),nicotine group (group NI) and electric vagal stimulation group (group VS).Nicotine 2 mg/kgwas injected intraperitoneally at 15 min after lung transplantation in group NI.Right cervical vagus nerve trank was stimulated for 20 min with continuous electric rectangular pulses (5 V,2 ms,1 Hz) at 10 min interval twice in total starting from 15 min after lung transplantation in group VS.Arterial blood samples were then collected for blood gas analysis at 15,30,45,75,105 and 135 min after lung transplantation.Arterial blood samples were then collected at 135 min after lung transplantation for determination of the plasma concentration of interleukin-6 (IL-6),IL-8 and tumor necrosis factor-α (TNF-α) by ELISA.The rats were sacrificed at 135 min after lung transplantation and the tissue of transplanted lung was removed for determination of lung injury score (LIS) according to the pathological changes obtained with light microscope,and of wet/dry lung weight ratio (W/D ratio).Results Compared with group C,PaO2 and pH value were significantly increased,and LIS,W/D ratio,and the concentrations of plasma IL-6,IL-8 and TNF-α were decreased in NI and VS groups.Conclusion Nicotine or electric vagal stimulation can attenuate injury to transplanted lungs in rats.

Objective To investigate impaired fasting glucose(IFG)status of office worker and enterprise personnel in Shiji-azhuang area,for providing a basis for early prevention of diabetes mellitus.Methods The fasting blood glucose level of 109 083 of-fice workers and enterprise personnel in Shijiazhuang area were detected in physical examination in 2012.Results The people of IFG (fasting blood glucose 5.6-<7.0 mmol/L)accounted for 14.61% in all subjects,1 6.61% in men,10.23% in women.3.5 1%male of the 18-<21 years old group were IFG.With the increasing of age,the ratio of IFG people gradually rised to a peak of 30.44% at the age group of 71-<76,and then decreased a little.While the proportion of female with IFG was 1.55% at 18-<21 years old group,with the increasing of age,to the age group of 5 1 - < 56 reached the first peak 20.27%,then decreased at the 56-<61 age group.Rapidly rising again,up to 31.74% the second peak in 76-<81 age group,and then decreased a little.Conclu-sion The proportion of IFG in male is higher than that in female.The proportion of IFG increases with age,and reaches the peak in a certain age (over 70 years old),and then at a relatively stable level.