Objective To evaluate the effects of the modified opration of benign tumor in parotid gland on the prevention of Frey syndrome.Methods the Parotid benign tumor resection in 28 cases were selected,according to the different treatment methods were divided into observation group of 12 cases,16 cases of the control group.The modified surgical patients in the observation group,two flap method,preservation,preservation of parotid masseter fascia in the branches of the great auricular nerve and parotid region resection,the control group was treated by routine tumors of the parotid gland and parotid superficial lobectomy or resection.Patients were followed up for 6 months to 1 years,underwent minor test,the incidence of Frey syndrome in 2 cases were recorded,postoperative incidence of Frey syndrome were compared.Results The incidence of Frey syndrome in the observation group was significantly reduced compared with the control group.The difference was statistically significant (χ2 =7.479,P <0.05 ). Conclusion The effects of modified opetation combined with secondry disc method in benign tumor of parotid gland on the prevention of Frey syndrome has obvious advantages comparing with the control.

A total of 62 patients with radical operation of esophageal carcinoma were divided into all-in-one nursing intervention group (research,n =32) and routine nursing group (control,n =30).With regards to postoperative flatus time,removal of chest tube drainage time,postoperative hospital stay and hospital costs,the research group was lower than the control group (P ＜ 0.05).After 2 weeks,from the postoperative quality of life questionnaire with the European Organization for Research and Treatment of Cancer,the scores of overall health of enteral nutrition group were higher than those of parenteral nutrition group while the symptom scores of fatigue,nausea & vomiting,insomnia,decreased appetite,constipation and economic difficulties were less than parenteral nutrition group (P ＜ 0.05).Early postoperative enteral nutrition can improve the quality of life in patients with esophageal cancer.

Objective To investigate the mRNA expression of a proliferation inducing ligand (APRIL) and its receptors including B cell maturation antigen (BCMA),transmembrane activator.calcium modulator and cyclophilin ligand interactor (TACI) in the peripheral blood mononuclear cells (PBMCs) of patients with systemic lupus erythematosus (SEE).Methods APRIL mRNA、BCMA mRNA and TACI mRNA in PBMCs were detected by real-time quantitative PCR in 66 SLE patients and 25 normal controls.Gene expression level was measured as 2-AACT.Results The expression levels of APRIL mRNA、BCMA mRNA and TACI-mRNA were significantly increased in both active SLE group and stable SLE group compared with those in the normal controls(P<0.01 for all).The expression levels of APRIL mRNA and TACI mRNA in active SLE group were significantly higher than those in stable SLE group(P<0.01,P<0.05,respectively).But there was no significant difierence in the expression levels of BCMA mRNA between the SLE stable and active groups-Beside,the expression levels of APRIL mRNA and TACI mRNA were significantly increased in patients with lupus nephritis (LN) compared to patients with non-LN (P<0.01 for all).Conclusion The expression levels of APRIL and its receptors are significantly elevated in SLE patients.It may suggest that APRIL and its receptors play an important role in the pathogenesis of SLE.

Objective To investigate the effect of all-in-one nursing intervention on esophageal carcinoma patients with bad emotion and immune function. Methods From the October, 2012 to the October, 2013, 102 patients with radical operation of esophageal carcinoma were divided into all-in-one nursing intervention group (research group, 52cases) and routine nursing group (control group, 50 cases) according to the random number table method.Two groups of patients were evaluated before and after operation of anxiety and depression emotion scores, with the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) .At the same time, two groups of patients were detected the stress and immune index before and after the operation. Results Before operation, two groups of patients with anxiety, depression, stress reaction and immune index were not significantly different (P>0.05).After operation, the study group patients with anxiety and depression scores were significantly lower than those in the control group [(34.6+6.7) points vs. (44.8+7.5) points, (33.7+6.9) points vs. (40.6+7.3) points], the difference was statistically significant (t values were 7.234, 4.902, P<0.05). Eighth days after operation, patients in the control group FBG, CRP and Cor levels were significantly higher in the study group [(6.98±1.12)mmol/L vs.(6.09±0.85)mmol/L,(18.11±5.93) mg/L vs.(9.24±3.22)mg/L,(293.98±69.09)nmol/L vs.(221.97±67.94)nmol/L],the difference was statistically significant (t values were 4.532, 9.336, 5.307, P<0.05). Eighth days after operation, two groups of patients with IgA, IgM were higher than first days after operation [(2.41±0.46)g/L vs.(1.89±0.56)g/L,(2.51±0.58) g/L vs.(1.35±0.67)g/L and (2.36±0.53)g/L vs.(1.82±0.46)g/L, (2.34±0.62)g/L vs. (1.37±0.64) g/L], the difference was statistically significant (t values were 5.174, 9.439, 5.549, 7.850, P<0.05).The total number of patients blood lymphocytes (LYM) and cytokines (CD3, CD4, CD8, CD4/CD8) were significantly higher than the control group [(2.87±0.65)×109/L vs.(1.98±0.58)×109/L, 0.62±0.10 vs. 0.57±0.07, 0.41±0.08 vs. 0.35 ±0.08, 0.24 ±0.04 vs. 0.26 ±0.05, 2.06 ±0.44 vs. 1.65 ±0.46], the difference was statistically significant (t values were 7.286, 2.915, 6.942, 2.225, 4.601, P<0.05). Conclusion All-in-one nursing intervention can significantly improve the anxiety and depression in patients with esophageal cancer in bad mood, enhance the immune function of patients, conducive to the rehabilitation of patients.

Objective To investigate the influences of transitional care on early quality of life in esophageal cancer patients after surgery.Methods A total of 1 95 patients with esophageal cancer were randomly divided into control group (98 cases,regular follow-up)and observation group (97 cases,transitional care)according to random number table.And then,the readmission rate of 2 months post discharge was compared in patients between two groups.Besides,quality of life of patients was evaluated with the quality of life questionnaire core 30 (QLQ-C30)at discharge and 2 months after intervention.Results The readmission rate of 2 months post-discharge of observation group and control group were 5.2%,16.3% with a significant difference (χ2 =6.332,P =0.01 2).There were no statistically significant differences in the scores of functional items and symptom items of QLQ-C30 (P >0.05).After the interventions,the scores of general health,emotional function and social function in observation group were higher than those in control group;the scores of fatigue, pain,insomnia,difficult breathing,loss of appetite in observation group were lower than those in control group;there were statistically significant differences between two groups (P <0.05).Conclusions Transitional care can provide positive guidance for living condition of patients with esophageal cancer,improve patients′living condition so as to improve patients′early quality of life.

Objective To investigate the effect of all-in-one nursing intervention on the stress response and postoperative quality of life in patients following esophageal cancer surgery .Methods From the October 2012 to March 2013 , 62 patients with radical operation of esophageal carcinoma were divided into all-in-one nursing intervention group (32 cases) and the routine nursing group (30 cases).The blood samples of the two groups of patients were collected before operation (surgery day) (T0) and on the fifth day after operation (T1) to measure stress response indicators , including fasting blood glucose ( FBG ) , C-reactive protein ( CRP ) , interleukin -6 (IL-6), plasma cortisol (Cor).And using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 ( QOL ) evaluated the early quality of life , before operation and the second week after opreation .Results The stress reaction index before operation had no significant difference between two group (P>0.05).On the fifth day after operation, the FBG, CRP and Cor levels of two groups were significantly higher than the preoperative level (t=3.724,7.203,4.137, respectively;P<0.05), but there was no significantly difference in the IL-6 level (t =0.452,P>0.05).The FBG, CRP, IL-6 and Cor levels of two groups on the fifth day after operation were significantly higher than the preoperative level ( t =3.031,5.361,2.864,3.534,6.990,10.755,2.415,8.166, respectively;P<0.05).Scores of each function item and symptom before operation had no significant difference between the two groups (P>0.05).And two weeks after the operation , the functions of the research group were higher than those in the control group ( P<0.05 ) .Symptoms scores of study group was lower than those in the control group , and there were statistically significant differences in seven aspects ( P<0.05), but the other two aspects had no significant differences (P>0.05).Conclusions All-in-one nursing intervention can significantly reduce stress reaction and improve the quality of life in postoperative patients with esophageal cancer .

Objective To explore the influences of integrated nursing care on bad emotion and immune function of postoperative patients with esophageal cancer. Methods A total of 102 postoperative patients selected from October 2012 to October 2013 were randomly divided into research group ( 52 cases, integrated nursing care) and control group(50 cases, routine nursing). Self rating anxiety scale (SAS) and self rating depression scale ( SDS) were used to evaluate the anxiety and depression of patients before and after operations. We detected the contents of immune index such as immunoglobulin ( IgA, IgG, IgM ) , peripheral blood lymphocyte count ( LYM ) , cytokine and etc. before operation, the first and eighth days after operation. Results Patients in the research and the control group all had anxiety and depression symptoms before operation. After operation, the scores of SAS (34. 6 ± 6. 7) and SDS (33. 7 ± 6. 9) of patients in the research group were lower than that in the control group (P<0. 05). Eighth days after operation, the contents of IgA and IgM rose again compared with that in the first postoperative day (t=5. 174,9. 439;P<0. 05). The contents of LYM and cytokine CD4/CD8 of patients in the research group were higher than that in the control group ( P<0. 05), and all of them were higher than that in the first postoperative day. Conclusions Integrated nursing care can relieve anxiety and depression of patients with esophageal cancer, enhance patients′immune function, and benefit patients′recovery.