ObjectiveTo observe the postoperational curative effect and complicational occuring status by using soft palate landscape orientation two fusiform cuts and enlarge two amygdales resection to treat(obstructive sleep apnea hyponea syndrome,OSAHS).Methods59 cases with type Ⅰ OSAHS were divided into experimental group(39 cases)using soft palate landscape orientation two fusiform cuts and enlarge two amygdales resection,control group( 20 cases)carrying out UPPP or keeping uvula UPPP.ResultsTow groups postoperational total effective rate 84.75％ (50/59),PSG survey's analysis( x2 =6.348,P ＜0.05 ) with preoperation,postoperation,without obvious discrepancy,the degree of postoperational pharyngeal ache,after follow-up visit 6-12 months,comparing the changes of snore,nasopharynx's backflow or missing deglutition and appearing cavum pharyngis coarctation( U =3.426,P ＜ 0.05 ),having outstanding discrepancy.ConclusionIt was not only to completely keeping uvula by using soft palate landscape orientation two fusiform cuts and enlarge two amygdales resection to treat OSAHS,but to enlarge soft palate shaping confines,not only effectively enlarging the ventilate's sectional area of cavum oropharyngeum,but preferably keeping the normal physiological morphology and function of cavum pharynges,avoiding the happening such as palatepharynx insufficiency complication etc.

Objective To evaluate the value of echocardiography on the diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC),and to improve the diagnositic accuracy of ARVC by echocardiography.Methods According to the 2010 European Heart Association guideline,twenty-one patients with ARVC were diagnosed from September 2003 to June 2014.The patients were divided into four groups (confirmed,suspiciously diagnosis,miss diagonisis,misdiagnosis) and the echocardiographic features were retrospectively analyzed including the right ventricular (RV) movement,the diameter of RV outflow tract (RVOTd),fractional area change of RV (RVFAC),the severity of tricuspid regurgitation (TR) and peak pulmonary artery systolic pressure (PASP).Results Of 21 patients,15 (71.4％) were confirmed by echocardiography,which had the typical ARVC echocardiographic features including the hypokinetic,akinetic or aneurysm of RV,dilation of RVOTd [mean RVOTd (40 ± 3)mm],and RV FAC＜33 ％ [mean (21 ± 7)％].TR were noticed in all the 15 patients but the PASP were normal [mean (27 ± 9)mmHg,1 mmHg =0.133 kPa].Three (14.3％) were suspiciously diagnosed which had the RV wall hypoakinetic,1 with pure RVOTd dilation and 2 with RV and RVOTd dilation,all 3 patients had mild TR,33％＜RVFAC ≤40％ and PASP were in normal range.Two patients had normal echocardiography which was miss diagnosed,one patient was misdiagnosed as dilated cardiomyopathy.Conclusions The different stages of ARVC patients had different echocardiographic features,the patients were easily diagnosed when the ARVC patients in RV failure stage.But for the early and late stage,the diagnosis should combine the clinical manifestation and other imaging facilities to avoid miss diagnosis and misdiagnosis.

【Objective】 To study the frequency, Rh phenotypes and molecular & biological background of D-elute (D^el) phenotype in RhD-negative blood donors in Dalian. 【Methods】 A total of 355 serologically RhD-negative samples between November, 2018 and October, 2019 in Dalian Blood Center were collected, and tested for RhC, c, E, e phenotypes using monoclonal antibodies and anti-D adsorption/elution test. DNA was extracted by magnetic bead selection. RHD 1227G>A mutation was detected by melting curve analysis. All RHD exons were sequenced by Sanger sequencing. 【Results】 Among 355 serologically RhD-negative blood donors, 55 (15.5%) were identified as D^el and the remaining 300 cases (84.5%) were true RhD negative. Ccee (45/55, 81.8%) was the predominant Rh phenotype among 55 D^el cases while ccee (210/300, 70.0%) was the most prevalent Rh phenotypes in 300 true RhD negative cases. In 55 D^el cases, 51 (92.7%) had RHD 1227G>A mutation, and the other 4 cases(7.3%) had mutations in other sites. 【Conclusion】 The frequency of D^el was 15.5% in serologically RhD-negative blood donors in Dalian, with Ccee being the most prevalent Rh phenotype and RHD 1227G>A the most common gene mutation.