1.Research progress of anti-osteoporotic effects of genistein
Wenxiu LAI ; Yajun YANG ; Liao CUI
Chinese Pharmacological Bulletin 2016;32(10):1345-1347,1348
Genistein, as one kind of phytoestrogens, can stimu-late osteoblastic proliferation, differention and mineralization, and can also inhibit bone resorption activity of osteoclast. The effect of genistein on bone metabolism lies in various molecular mechanisms. This paper reviews the research progress of the an-ti-osteoporotic action of genistein and its mechanism, which may provide a basis for the research and development of new agents to treat osteoporosis.
2.Research progress of regulatory effects of water-soluble compounds isolated form Salvia miltiorrhiza on bone metabolism
Shuhui LI ; Yanlong LIANG ; Yajun YANG ; Wenxiu LAI ; Liao CUI
Chinese Pharmacological Bulletin 2016;32(7):902-905
Salvia miltiorrhiza is a traditional Chinese medicine for the treatment of cardiovascular diseases .Recently, increasing evidence demonstrates that the water-soluble compounds isolated from Salvia miltiorrhiza,including tanshinol and salvianolic acid B, exert a regulatory influence on bone metabolism .The under-lying mechanism of these compounds involves various pathways , such as Wnt/β-catenin, ERK, BMP, OPG/RANKL/RANK and FoxO mediated oxidative stress pathway .This paper reviews pre-vious effects and mechanism of polyphenolic acids in Salvia milt-iorrhiza , which may provide the base for the research and devel-opment of the new agents to treat osteoporosis .
3.Abdomen-rubbing qigong exercise and health preservation concept of Fang Kai, a Xin’an medical physician
Yang LIU ; Ling HU ; Dandan LAI ; Wenxiu DUAN ; Jing XU ; Zijian WU ; Tanming LI
Journal of Acupuncture and Tuina Science 2016;14(3):170-174
The abdomen-rubbing qigong exercise was first developed by Fang Kai, a Xin’an medical practitioner. It’s an essential part of Xin’an health preservation works. This health preservation method integrates massage with Daoyin and integrates meridian theory with Zangxiang theory. It’s safe, simple and has no side effects. Practice of this qigong exercise can protect the spleen and stomach, tonify qi and essence, harmonize Ying-Nutrients and Wei-Defense, unblock meridians and circulate qi. This paper aims to summarize and promote this exercise.