1.Green computing-based construction of hospital information system
Yingjuan LI ; Yanhua LU ; Wenxiu GUO
Chinese Journal of Medical Library and Information Science 2016;25(4):68-73
Energy conservation has become a problem needing to be immediately solved with the extensive con-struction of hospital information system. As a high computing technology, green computing uses resources economically and effectively and is characterized by energy conservation and environment friendship. Its concept and characteristics, and the status quo of hospital information system construction were described. A green computing framework model was established for hospital information system construction, which plays an active role in implementing the idea of green environment protection, low carbon and energy conservation, and sustainable development, thus laying a foundation for studying the mechanisms underlying energy conservation in hospital information system construction and for assessing and optimizing its strategic system.
2.Computing thinking-based teaching reform of computer network course
Xiaojing SHI ; Xiaoping Lǚ ; Wenxiu GUO
Chinese Journal of Medical Library and Information Science 2017;26(6):63-66
Computing thinking is one of the hotspots in computer education field,computer network is the core course of computer,and social information process is increasing the need of computer network professionals.The characteristics of computer network course,teaching of computer network course and problems related with teaching of computer network course were analyzed in aspects of its teaching contents,teaching methods and examination methods in order to train more excellent applied professionals of computer network and improve the computing thinking of undergraduates.The ways or methods for training the computing thinking of undergraduates were put forward,which can thus provide new ideas for the teaching reform of computer network course in colleges and universities.
3.Design of Non-Invasive Blood Oxygen Measurement Based on AFE4490.
Jinsong ZHU ; Shouhao WU ; Wenxiu GUO ; Hui ZHENG ; Dong TANG
Chinese Journal of Medical Instrumentation 2015;39(5):341-343
From the perspective of portable monitoring devices,we use an analog front-end AFE4490 design a module of Non-invasive blood oxygen measurement, used to collect human pulse wave signal and peak (valley) value detection and then use the principles of non-invasive oximetry calculated oxygen saturation (SPO2). This design of noninvasive oximetry module has the characteristics of small size, low power consumption, and the results of test show that the measurement of oxygen saturation are correct.
Heart Rate
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Humans
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Oximetry
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instrumentation
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methods
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Oxygen
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blood
4.Assessment of the value of academic libraries
Wenxiu GUO ; Xiaojing SHI ; Ruizhen KONG ; Yongxu YUAN
Chinese Journal of Medical Library and Information Science 2015;(1):33-37
Assessment of the value of academic libraries is an effective means to describe the value of academic libraries themselves. The dimension and factors for the assessment of the value of domestic and foreign academic li-braries were analyzed according to the assessment of the value of Shanxi Medical University Library, and the frame-work for the assessment of the value of academic libraries was proposed in terms of the impact of academic libraries on higher education.
5.Fundamental research in drug toxicology of China:analysis based on ″drug toxicology″ projects funded by National Natural Science Foundation of China between 2001 and 2015:a review
Jingfeng SONG ; Minnan LU ; Wenxiu GUO ; Zhenyu WANG
Chinese Journal of Pharmacology and Toxicology 2016;30(3):190-196
Drug toxicology,as a discipline which studies drug toxicity mechanisms and evaluates comprehensive drug safety is of crucial importance for guiding sensible clinical drug use,reducing adverse drug reactions and reducing failures of new drug development caused by toxicity. This article summarizes the basic situation of Natural Science Foundation of China(NSFC)funded projects in drug toxicology between 2001 and 2015,involving the amount of approved grants,funding rate,funding category and supported faculty,and the change of NSFC guidelines. Research topics,ideas and contents of NSFC funded projects are generalized and characteristics,problems and future trends are also analyzed to provide reference for research on drug toxicology.
6.National Natural Science Foundation-supported papers in the field of epidemiological methods and health statistics: A trend analysis
Rui LIAO ; Dingyun YOU ; Zhenyu WANG ; Wenxiu GUO ; Le CAI
Chinese Journal of Medical Library and Information Science 2017;26(6):22-25,75
The National Natural Science Foundation-supported papers in the field of epidemiological methods and health statistics since 1987 were analyzed by trend analysis in order to have a better understanding of the development,current situation and history in the field of epidemiological methods and health statistics,and provide reference for the selection of topics,approval of projects and optimization of supporting structure in the field of epidemiological methods and health statistics.
7.Market Analysis of Medical Full-Text Database
Wenxiu GUO ; Peiring HE ; Xiuping WANG ; Xiangqian PEI
Journal of Medical Informatics 2009;30(7):45-48
The paper analyzes the supply, demands and market mechanism characteristics of medical full - text databases frequently used in college and university libraries. Some suggestions are proposed according to current status of medical full - text database market, including establishing science and technology information center, discovering more channels to get more free full - text and regulating the market by government guide.
8.Clinical Significance of MALT1 Gene Detection in Extra-nodal B Cell Lymphoma
Hongwei GUO ; Wenxiu YANG ; Yu ZHONG ; Yumei CHEN ; Song WANG ; Oilan LIU ; Hui LIU
Chinese Journal of Clinical Oncology 2010;37(6):320-322,326
Objective: To investigate the relationship between MALT1 mRNA expression in extranodal B cell lymphoma and the pathogenesis of MALToma and DLBCL, and to explore the effect of MALT1 mRNA expression on the clinicopatho-serve the expression of Bcl-2 and Ki-67 in 106 samples of extranodal B cell lymphoma.The mRNA of MALT1 was detected by RT-PCR.Clinicopathological data were reviewed.Follow-up and statistical analysis were performed.Results: Expression of MALT1 mRNA was statistically different between the cases with lymph node metastasis and those without lymph node mestastasis, and between staging Ⅰ-Ⅱ cases and stage Ⅲ-Ⅳ cases, The expression of MALT1 mRNA in cases with posi-tive expression of MALToma, DLBCL, and Bcl-2 was higher than in those without expression of the three indices (P<0.05).However, no significant difference was found in MALT1 mRNA expression between cases with Ki-67≥30% and those with Ki-67<30% (P>0.05).MALT1 mRNA-positive cases showed a worse survival status than MALT1 mRNA-negative cases (P<0.05).Conclusion: Expression of MALT1 gene is different between MALToma and DLBCL.Inhibition of apoptosis by Bcl-2 overexpression caused by activation of NF-κB may lead to the pathogenesis of MALToma and DLBCL.The expression of MALT1 mRNA is associated with the types of lymphoma, involvement of lymph node, stage of lymphoma, and patient sur-vival.The expression of MALT1 gene may be associated with poor prognosis of MALToma and DLBCL.
9.Prevalence analysis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features in a Third Class A Level Hospital in Guiyang
Yonghui GUO ; Nianchun PENG ; Lixin SHI ; Qiao ZHANG ; Ying HU ; Yining XIANG ; Wenxiu YANG
Chinese Journal of Endocrinology and Metabolism 2018;34(11):915-919
Objective To analyze of the prevalence of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) and noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) by 2017 World Health Organization ( WHO) classification of tumors of endocrine organs in Guiyang. Methods A retrospectively analysis of patients who had a thyroid surgery and confirmed thyroid cancer by pathological diagnosis in the Affiliated Hospital of Guizhou Medical University from 2009 to 2016. PTC and FVPTC by 2014 WHO classification of tumors of endocrine organs , and according to the 2017 WHO classification of tumors of endocrine organs ,the thyroid papillary carcinomas were reviewed and some had been confirmed as EFVPTC and NIFTP, with analysis of the prevalence and prognosis of NIFTP. Results Of the 1207 cases of thyroid carcinoma, 1150 cases were papillary carcinoma, the constituent ratio of thyroid carcinoma was 95.28%, the FVPTC was 72 cases, and the proportion of thyroid carcinoma was 5. 97%; the proportion of FVPTC in thyroid carcinoma decreased from 2009 to 2016 ( P <0.05). After pathological sections being reviewed, 10 cases had been confirmed as non-encapsulated infiltrative FVPTC, the ratio of thyroid cancer to thyroid cancer was 0.83%; EFVPTC was found in 62 cases, accounting for 5.14% of thyroid carcinoma, these included 2 cases of NIFTP confirmed by the 2017 WHO classification of tumors of endocrine organs and 60 cases encapsulated invasive FVPTC, the percentage of thyroid carcinoma was 0.17% and 4.97%. 62 cases of EFVPTC with the exception of 11 cases without further visit, while the remaining 51 cases of EFVPTC were followed up. Death, local or distant metastases were defined as adverse events. An adverse event was seen in 11 of 49 of the cases of invasive EFVPTC, including 2 died of disease; The NIFTP were alive with no evidence of disease. Conclusion The diagnosis of NIFTP according to new WHO classification of endocrine organ tumors in 2017 has little expected impact in Guiyang.
10.Effect of a space stabilizing device on the capacity for osteogenesis in the bone-grafted area
Endian SU ; Sulin CHEN ; Jianbin GUO ; Wenxiu HUANG ; Dong WU
STOMATOLOGY 2023;43(3):233-236
Objective:
To study the effect of a space stabilizing device on the capacity for osteogenesis in the bone-grafted area.
Methods:
Patients with anterior teeth defects as well as labial alveolar ridge defects were randomly divided into two groups: the experimental group was treated using a space stabilization device after guided bone regeneration whereas the control group received regular guided bone regeneration. The CBCT data was analyzed prior to, immediately and 6 months after procedure to compare the osteogenesis with or without the device.
Results:
Seventeen bone-grafted sites were examined(7 in the experimental group and 10 in the control group). At 2 mm and 4 mm below the alveolar ridge, the horizontal bone resorption rate in the experimental group was significantly lower than the corresponding level in the control group(P=0.001). The horizontal bone resorption rate at 2 mm below the alveolar ridge of each group was significantly higher than that at 4 mm below the alveolar ridge in corresponding groups(P=0.003).
Conclusion
The space stabilizing device used in this study has a positive clinical impact on preserving space stability and minimizing bone resorption.