Objective To evaluate the application of diffusion-weighted MR imaging in hepatic echinococcosis.Methods Diffusion-weighted MR imaging and measurement of apparent diffusion coefficient (ADC)were performed in 23 patients with 30 hepatic echinococcosis(cystic echinococcosis 24, alveolaris echinococcosis 6).Results The mean ADC values of cystic echinococcosis, alveolaris echinococcosis and normal liver were (3.50?0.35)?10 -3 mm2/s,(2.22?0.22)?10 -3 mm2/s and (1.41?0.09)?10 -3 mm2/s respectively.The difference between the mean ADC values was significant(?

on on PWI. Conclusions MRI can demonstrate hydatid cysts in vertebra, spinal canal, paravertebral and neighboring soft tissue. MRI is a valuable tool in the diagnosis and treatment planning of hydatid disease of the spine.

Objective To study the characteristic findings of brain echinococcosis on MRI. Methods The MRI findings of 18 patients with pathologically confirmed brain echinococcosis were retrospectively reviewed.Results Among the patients.there were 9 cases of cystic echinococcosis and 9 cases of alveolar echinococcosis.In cystic echinococeosis,MRI revealed homogeneously hypointensity on T1WI and hyperintensity on T2WI,while it showed low signal intensity inside the cysts on FLAJR and DWI. In 6 cases of cystic echinococcosis, no edema was detected surrounding the lesions,while edema resulting from cyst rupture was found in 3 cases.The cystic walls were visible in 6 csses, obscure in 3 cases.The ruptured hydatid cysts in 3 cases showed slight ring enhancement.Alveolar echinococcosis appeared as multiple lesions with isointensity on T1WI and hypointensity on T2WI,surrounded by vasogenic edema.The "charcoal-like"hypointensity and innumerous hyperintense bubbles of 1-10 mm in diameter inside the lesions on T2-weighted MR images were characteristic for lesions of alveolar echinococcosis.The lesions revealed hypointensity on DWI and showed irregular ring enhancement after injection of Gd-DTPA. Perfusion-weighted MR imaging revealed low relative cerebral blood volume.Conclusion MRI can demonstrate lesions of brain echinococcosis accurately due to its advantages of multiorientation and multiparameter.It is clinically valuable.

Objective To analyze the MRI features of fibrocystic breast disease (FBD). Methods 39 patients with pathologically proven FBD were retrospectively reviewed. The imaging protocol consisted of pro-contrast imagings and bilateral breast volume im-aging for breast assessme NT(VIBRANT). MRI features were interpreted based on the morphologic and enhancement kinetic de-scriptors defined on ACR DIRADS-MRI lexicon. Results There were 3 types on ACR BI-RADS-MRI lexicon in FBD,including 13 focal mass-type showing malignant enhancement kinetic pattern mostly;15 cyst-type with non-enhancement or mild enhance-ment,of them,1 case with periductal mastiffs showing strong enhancement and rapid up-slope and wash-out mimicking a breast cancer. 6 non-mass type usually showing benign enhancement kinetic pattern. In 5 patients,MRI did not show definite abnormal evi-dence. Conclusion MRI is of significant value in diagnosing FBD.

Objective To evaluate whether the functional MRI could be used to reflect the change of angiogenesis after drug treat-ment,and obtain the related semi quantitative and quantitative parameters by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).Methods The subcutaneous transplantation colorectal cancer were constructed in 20 nude mice,which were treated with Xiaoaifeimi.The transplanted tumor microvascular density,VEGF and PCNA were monitored.The therapeutic effect and MRI monitoring results were evaluated by combining DCE-MRI with the pharmacokinetic model.The semi quantitative and quantitative parameters were obtained for evaluating the effection of medicine.Half of nude mice were sacrificed to obtain the immunohistochem-ical staining.Correlation between pathological findings and parameters were analyzed.Results Compared to the control group,hu-man colon HT-29 cell proliferation rate was significantly decreased (44.87%)(P <0.05),and the apoptosis rate of HT-29 cells was increased 2.45 times (P <0.05)after Uyghur medicine treatment.The correlation between pathological examination and DCE-MRI parameters showed that Ktrans value and Kep were positively correlated with VEGF,MVD and PCNA (P <0.05).Conclusion A good relationship is showed between immunohistochemistry and DCE-MRI quantitative parameters in Uygur drug treating human colon cancer mice.

The Establishment and improvement of the scientific research incentive mechanism is the key to optimize the internal management, improve the performance, enhance the core competitiveness of the hospital.Research time and energy is limited because University Affiliated Hospital Medical Staff are in charge of medical treatment, teaching and scientific research.It's very important to mobilize the scientific research enthusiasm of the medical staff by using the scientific research incentive mechanism and promote the scientific research strength of hospital.This paper introduced the scientific research incentive mechanism and the achievements in the Second Affiliated Hospital of The Xinjiang Medical University.The exploration and thinking on the results and the existing problems are proposed in the paper.

Objective To investigate the clinical application of magnetic resonance hydrography(MRH) in diagnosing cystic echinococcosis(CE).Methods 47 cases with CE were proved by surgery and pathology.All cases were examed by MRI and MRH.Results Among the 151 lesions in 47 cases,the sensitivity and specificity in diagnosis of CE were 61.59% and 93.33% for MR imaging,92.05% and 86.67% for MRH,respectively.Conclusion The detecting rate of MRH was significant high than that of MRI,MRH combined with MRI has more advantages in diagnosis of CE.

0.05). Conclusion Comparedwith DSA and operation,there is excellent correlation among 3D contrast-enhanced moving-bed MRA,DSA and operation.MRA canaccurately and entirely assess occlusive disease of the arteries of the lower extremity.It is a ono-invasive,reliable and potential newtechnique.

Objective To study the value of CT scan in diagnosis and clinical therapy of thyroid diseases.Methods CT findings in 61 cases with various thyroid diseases confirmed pathologically were analyzed retrospectively.Results ① 9 patients were Hashimoto’s thyroiditis.Of them,5 cases were diffuse lesions and 4 localized at one enlarged lobe and 1 with calcification.② 28 cases with hyperplasia included 2 Graves disease of diffuse lesions with enlargement and 26 nodular hyperplasia.There were calcification in 8 and cystic change in 13.③ 24 cases of thyroid tumor included 14 thyroid adenomas with complete circumscribed enhanced ring around the lesion,10 of them were in company with cystic change and 4 with calcification.13 cases were single lesion and one case was mattiple lesions.10 thyroid carcinoma,3 cases were in company with cystic change and 7 with calcification.Metastasis of cervical lymph nodus was found by CT in 7 cases.Metastatic lymph nodes presented marked enhancement,cystic change and calcification.Conclusion CT scan both plain and contrast-enhanced are beneficial for the detection of thyroid diseases,and is also important for planning the management and predicting the prognosis of this disease.

Objective To investigate the value of dual-source CT perfusion imaging in evaluation of liver fibrosis stage.Methods Liver fibrosis models were established with 35 rabbits (experimental group)which were intraperitoneally injected with carbon tetra-chloride.Meanwhile,other 5 rabbits were regarded as control group which were intraperitoneally inj eced with physiological saline.7 rabbits of experimental group and 1 of control group were undergone dual-source CT perfusion scan at 4,6,8,10,12 weeks respec-tively.Arterial liver perfusion (ALP),portal venous perfusion (PVP),total hepatic perfusion (THP),hepatic perfusion index (HPI)were recorded,and staging of liver fibrosis were assessed by pathological method.Results With the increase of liver fibrosis degree,HPI showed an upward trend,whereas PVP was opposite.HPIs of S2,S3 and S4 stage were significantly different com-pared to that of control group respectively.The differences of HPI between S3,S4 stage to S0 and S1 stage were significant.PVP between S2,S3,S4 stage to S0 stage and S1 stage were also significant different.Conclusion HPI and PVP can reflect the perfu-sion changes of liver fibrosis stages.Combination of HPI and PVP may help the diagnosis of S2,S3 or S4 stage of liver fibrosis.