1.MRI features of hydatid disease of the spine
Shayiti MIRIGULI ; Wenxiao JIA
Chinese Journal of Radiology 2009;43(8):858-861
on on PWI. Conclusions MRI can demonstrate hydatid cysts in vertebra, spinal canal, paravertebral and neighboring soft tissue. MRI is a valuable tool in the diagnosis and treatment planning of hydatid disease of the spine.
2.MRI findings and diagnosis of brain echinococcus
Shayiti MIRIGULI ; Wenxiao JIA
Chinese Journal of Radiology 2010;44(7):700-703
Objective To study the characteristic findings of brain echinococcosis on MRI. Methods The MRI findings of 18 patients with pathologically confirmed brain echinococcosis were retrospectively reviewed.Results Among the patients.there were 9 cases of cystic echinococcosis and 9 cases of alveolar echinococcosis.In cystic echinococeosis,MRI revealed homogeneously hypointensity on T1WI and hyperintensity on T2WI,while it showed low signal intensity inside the cysts on FLAJR and DWI. In 6 cases of cystic echinococcosis, no edema was detected surrounding the lesions,while edema resulting from cyst rupture was found in 3 cases.The cystic walls were visible in 6 csses, obscure in 3 cases.The ruptured hydatid cysts in 3 cases showed slight ring enhancement.Alveolar echinococcosis appeared as multiple lesions with isointensity on T1WI and hypointensity on T2WI,surrounded by vasogenic edema.The "charcoal-like"hypointensity and innumerous hyperintense bubbles of 1-10 mm in diameter inside the lesions on T2-weighted MR images were characteristic for lesions of alveolar echinococcosis.The lesions revealed hypointensity on DWI and showed irregular ring enhancement after injection of Gd-DTPA. Perfusion-weighted MR imaging revealed low relative cerebral blood volume.Conclusion MRI can demonstrate lesions of brain echinococcosis accurately due to its advantages of multiorientation and multiparameter.It is clinically valuable.
3.Applications in Evaluation of Diffusion-weighted MR Imaging in Hepatic Echinococcosis
Journal of Practical Radiology 2001;0(07):-
Objective To evaluate the application of diffusion-weighted MR imaging in hepatic echinococcosis.Methods Diffusion-weighted MR imaging and measurement of apparent diffusion coefficient (ADC)were performed in 23 patients with 30 hepatic echinococcosis(cystic echinococcosis 24, alveolaris echinococcosis 6).Results The mean ADC values of cystic echinococcosis, alveolaris echinococcosis and normal liver were (3.50?0.35)?10 -3 mm2/s,(2.22?0.22)?10 -3 mm2/s and (1.41?0.09)?10 -3 mm2/s respectively.The difference between the mean ADC values was significant(?
4.MR Imaging Features of Fibrocystic Breast Disease
Hui XU ; Wenxiao JIA ; Yan LIU
Journal of Practical Radiology 2010;26(2):246-250
Objective To analyze the MRI features of fibrocystic breast disease (FBD). Methods 39 patients with pathologically proven FBD were retrospectively reviewed. The imaging protocol consisted of pro-contrast imagings and bilateral breast volume im-aging for breast assessme NT(VIBRANT). MRI features were interpreted based on the morphologic and enhancement kinetic de-scriptors defined on ACR DIRADS-MRI lexicon. Results There were 3 types on ACR BI-RADS-MRI lexicon in FBD,including 13 focal mass-type showing malignant enhancement kinetic pattern mostly;15 cyst-type with non-enhancement or mild enhance-ment,of them,1 case with periductal mastiffs showing strong enhancement and rapid up-slope and wash-out mimicking a breast cancer. 6 non-mass type usually showing benign enhancement kinetic pattern. In 5 patients,MRI did not show definite abnormal evi-dence. Conclusion MRI is of significant value in diagnosing FBD.
5.Evaluation of Uygur medicine in treatment of tumor by dynamic contrast-enhanced magnetic resonance
Xiaoqin LI ; Lin JIA ; Hong WANG ; Wenxiao JIA
Journal of Practical Radiology 2016;32(7):1119-1122
Objective To evaluate whether the functional MRI could be used to reflect the change of angiogenesis after drug treat-ment,and obtain the related semi quantitative and quantitative parameters by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).Methods The subcutaneous transplantation colorectal cancer were constructed in 20 nude mice,which were treated with Xiaoaifeimi.The transplanted tumor microvascular density,VEGF and PCNA were monitored.The therapeutic effect and MRI monitoring results were evaluated by combining DCE-MRI with the pharmacokinetic model.The semi quantitative and quantitative parameters were obtained for evaluating the effection of medicine.Half of nude mice were sacrificed to obtain the immunohistochem-ical staining.Correlation between pathological findings and parameters were analyzed.Results Compared to the control group,hu-man colon HT-29 cell proliferation rate was significantly decreased (44.87%)(P <0.05),and the apoptosis rate of HT-29 cells was increased 2.45 times (P <0.05)after Uyghur medicine treatment.The correlation between pathological examination and DCE-MRI parameters showed that Ktrans value and Kep were positively correlated with VEGF,MVD and PCNA (P <0.05).Conclusion A good relationship is showed between immunohistochemistry and DCE-MRI quantitative parameters in Uygur drug treating human colon cancer mice.
6.Application of prone-straddle position for transvaginal hysteromyomectomy in the posterior wall of the uterus
Xiaobing HE ; Xinjuan MA ; Wenxiao HU ; Yong MAO ; Zhenxiang JIA
Journal of Regional Anatomy and Operative Surgery 2015;(5):497-498,499
Objective To discuss the safety and advantages of prone-straddle position applied in transvaginal hysteromyomectomy of the posterior wall of the uterus. Methods The clinical data of patients who were admitted into our hospital from March 2013 to Janaury 2015 and received transvaginal hysteromyomectomy were retrospectively analyzed. They were divided into group A ( prone-straddle position, 30 cases) and group B (traditional lithotomy position,24 cases). The exposure of operative field, convenience of operation, time of the placement, time of operation, patient satisfaction, as well as patients’ heart rate, blood pressure, and oxyhemoglobin saturation were observed and ana-lyzed. Results Compared with the lithotomy position, there were significant differences in the time of the placement and the time of opera-tion in the patients treated by prone-straddle position. The patients with prone-straddle position cooperated well, and there was no obvious discomfort. Their vital signs were stable during the operation. The operative field during prone-straddle position exposed better and it was more convenient which make the operation became easier for both the operators and nurses. Conclusion Prone-straddle position applied in transvaginal hysteromyomectomy of the posterior wall of the uterus is safe and practicable, and it is valuable for clinical application.
7.The Clinical Value of CT in Diagnosis of Thyroid Disease
Daidi JIANG ; Wenya LIU ; Wenxiao JIA ; Jun DANG ; Yuhua ZHANG
Journal of Practical Radiology 2001;0(08):-
Objective To study the value of CT scan in diagnosis and clinical therapy of thyroid diseases.Methods CT findings in 61 cases with various thyroid diseases confirmed pathologically were analyzed retrospectively.Results ① 9 patients were Hashimoto’s thyroiditis.Of them,5 cases were diffuse lesions and 4 localized at one enlarged lobe and 1 with calcification.② 28 cases with hyperplasia included 2 Graves disease of diffuse lesions with enlargement and 26 nodular hyperplasia.There were calcification in 8 and cystic change in 13.③ 24 cases of thyroid tumor included 14 thyroid adenomas with complete circumscribed enhanced ring around the lesion,10 of them were in company with cystic change and 4 with calcification.13 cases were single lesion and one case was mattiple lesions.10 thyroid carcinoma,3 cases were in company with cystic change and 7 with calcification.Metastasis of cervical lymph nodus was found by CT in 7 cases.Metastatic lymph nodes presented marked enhancement,cystic change and calcification.Conclusion CT scan both plain and contrast-enhanced are beneficial for the detection of thyroid diseases,and is also important for planning the management and predicting the prognosis of this disease.
8.The analysis and thinking of Incentive mechanism and its results in a hospital
Jianping SHI ; Hongwei YAO ; Aihaiti GULIZHAER ; Wenxiao JIA
Chinese Journal of Medical Science Research Management 2016;29(2):85-87
The Establishment and improvement of the scientific research incentive mechanism is the key to optimize the internal management, improve the performance, enhance the core competitiveness of the hospital.Research time and energy is limited because University Affiliated Hospital Medical Staff are in charge of medical treatment, teaching and scientific research.It's very important to mobilize the scientific research enthusiasm of the medical staff by using the scientific research incentive mechanism and promote the scientific research strength of hospital.This paper introduced the scientific research incentive mechanism and the achievements in the Second Affiliated Hospital of The Xinjiang Medical University.The exploration and thinking on the results and the existing problems are proposed in the paper.
9.Application of MR PROSET Technique in Diagnosing Spinal Nerve Roots Diseases
Hong WANG ; Hao WANG ; Wenxiao JIA ; Jingxu MA
Chinese Journal of Medical Imaging 2010;(1):29-31
Purpose To investigate the clinical value of MR PROSET technique in showing and diagnosing in lumbarsacral nerve root diseases.Materials and Methods Conventional MRI sequence and PROSET sequence coronal images were performed in lumbosacral nerve roots of 15 healthy volunteers and 47 low back pain patients,each case performed 3D maximum intensity projection (3D MIP) post-processed.Spinal nerveroots were observed.Results The PROSET could show dura,dura sheath,spinal nerveroot,ganlias,segments of the nerves posterior to the ganglions well and could be observed from multiple aspects by the 3D MIP.Among the 47 cases of luber nerve root disease,PROSET could show the level of the invasion and compression to the ganglias.Conclusion According to the PROSET technique and conventional MRI picture,can provide the satisfied proof to the diagnosis of lumbosacral nerve root diseases.
10.The value of dual-source CT perfusion imaging in evaluation of rabbit liver fibrosis
Hao WANG ; Fan TAN ; Wenxiao JIA ; Hong WANG ; Yunling WANG
Journal of Practical Radiology 2014;(4):675-678
Objective To investigate the value of dual-source CT perfusion imaging in evaluation of liver fibrosis stage.Methods Liver fibrosis models were established with 35 rabbits (experimental group)which were intraperitoneally injected with carbon tetra-chloride.Meanwhile,other 5 rabbits were regarded as control group which were intraperitoneally inj eced with physiological saline.7 rabbits of experimental group and 1 of control group were undergone dual-source CT perfusion scan at 4,6,8,10,12 weeks respec-tively.Arterial liver perfusion (ALP),portal venous perfusion (PVP),total hepatic perfusion (THP),hepatic perfusion index (HPI)were recorded,and staging of liver fibrosis were assessed by pathological method.Results With the increase of liver fibrosis degree,HPI showed an upward trend,whereas PVP was opposite.HPIs of S2,S3 and S4 stage were significantly different com-pared to that of control group respectively.The differences of HPI between S3,S4 stage to S0 and S1 stage were significant.PVP between S2,S3,S4 stage to S0 stage and S1 stage were also significant different.Conclusion HPI and PVP can reflect the perfu-sion changes of liver fibrosis stages.Combination of HPI and PVP may help the diagnosis of S2,S3 or S4 stage of liver fibrosis.