1.The relationship between coronary artery lesions and malignant arrhythmia in STEMI patients
Journal of Chinese Physician 2014;(6):787-790
Objective To investigate the relationship between the severity of coronary artery disease and malignant arrhythmia in the acute ST segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI), and guide clinical prevention and treatment .Methods By retrospective analysis method , 418 cases of hospitalized patients with a diagno-sis of STEMI undergoing direct PCI were continuously collected in the Department of Cardiology , the First Affiliated Hospital of China Medical University, from 2008 January to 2010 December.Electrocardiography (ECG) was given after admission.Those patients were divided into two groups according to whether the occurrence of malignant ventricular arrhythmias that was defined as sustained ventricu -lar tachycardia (sVT) or ventricular fibrillation (VF)].In sVT/VF patients, the preoperative and postoperative groups were divided according to sVT/VF time.The degree of coronary artery lesions was calculated in patients with STEMI .The incidence of sVT/VF was counted in each group with Gensini scores <60,≥60 and<120, and ≥120.The relationship between the severity of coronary le-sions and malignant arrhythmia was observed in STEMI undergoing direct PCI patients .Results ⑴In this study , a total of 47 cases ( 11.2%) occurred with sVT/VF in patients;Killip grade >I, fast heart rate , low blood pressure , and low ejection fraction were risk factors of sVT/VF( P <0.05).The occurrence of sVT/VF among the Gensini groups were significant difference (7.1%vs 10.8%vs 20.5%, P =0.012 ) .⑵The occurrence of sVT/VF was 44.8% ( 22 patients ) with direct PCI before operation; the preoperative sVT/VF rate among the Gensini groups had significant difference (2.1%vs 5.9%vs 9.6%, P =0.045).⑶The occurrence of sVT/VF is 53.3%(25 patients) with direct PCI after operation; the postoperative sVT/VF rate among Gensini groups had no significant difference(5.0%vs 4.9%vs 11.0%, P =0.142);⑷Paired with age ( x±2), gender, hypertension, and diabetes 1, Logistic re-gression analysis showed that the heart rate greater than 80 beats /min ( P =0.04 , OR:2.667 , 95%CI:1.043~6.815 ) was an independent risk factor of preoperative sVT/VF, that Gensini score was not an independent risk factor of preoperative malignant ar -rhythmia.Conclusions For STEMI PCI patients, the more serious the degree of coronary artery is , the higher may be preoperative malignant arrhythmia , while the postoperative malignant arrhythmia rate has no significant difference .
2.Role of CT in diagnosis and treatment of non-alcoholic fatty liver by TCM
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(12):-
Objective:To observe the curative effect of traditional Chinese medicine on non-alcoholic fatty liver patients and CTN(computerized tomographynumber)of liver,than to appraise the role of assessment and diagnosis on non-alcoholic fatty liver for CT.Methods:60 patients with non-alcoholic fatty liver were divided into treatment group and contrast group in average,the patients in treatment group were treated by Xiaozhihugan capsule and Dangfeiliganning capsule,and those in contrast group were treated by Kezhi capsule and Shuifeijibin capsule.Changes of symptom,liver function,blood fat,ultrasonic report and liver CTN were observed.Results:In the treat group,the liver function,blood fat and liver CT value were improved obviously,which had superiority to that of contrast group.CT can diagnose the degree of fatty liver accurately and appraise curative effect,but ultrasonic report has no specific data and is inconvenient to statistics.Conclusions:Treatment group has notable curative effect on non-alcoholic fatty liver;CT is the important index of diagnosis and appraisement of curative effect on non-alcoholic fatty liver.
3.Therapeutic Effect of milrinone in Treatment of Refractory Heart Failure Patients
Wenxia ZONG ; Li LIN ; Chang LI
Herald of Medicine 2001;(3):156-157
Objective:To evaluate the effect of milrinone in treating refractory heart failure.Methods:5mg of milrinone in 250ml of 5% Glucose or 0.9% NaCl Solution were given daily by intravenous drip to 56 cases of refractory heart failure for a period of consecutive 7 days.The symptoms and signs were observed before and after the treatment,heart rate,blood pressure and heart function examined by Doppler echocardiography.Results:a.The total effective rate was 85.7%.b.The left ventricular ejection fraction (LVEF) and fraction shortening (FS) were increased significantly (P<0.01) after treatment.The rate of filling velocity in early diastole (E) over that in late diastole (A) was increased significantly (P<0.05).Conclusion:Milrinone has good effect for treating refractory heart failure.It improves not only the cardiac systolic function but also the diastolic function.
4.A method of plethysmography wave de-noising based on wavelet transform and spline interpolation
Yuhua ZHA ; Wei LI ; Wenxia CHEN
China Medical Equipment 2015;(10):27-29
Objective: To eliminate the noise of the plethysmography wave and obtain plethysmography wave signal without noise. Methods:Using sym4 and combining the improved wavelet threshold wavelet algorithm to remove high frequency white noise of plethysmography wave, and then using spline differential fitting method to remove baseline drift of pulse wave volume. Results:The experimental results show that the high frequency noise and baseline drift of plethysmography wave have been removed effectively processed by the sym4 wavelet and combining with improved threshold of wavelet algorithm and spline difference after fitting. Conclusion:The method can well remove the noise of the plethysmography wave and retains the effective information of plethysmography wave effectively.
5.Y-shaped osteotomy for congenital coxa vara
Yunhui TONG ; Fuan WAN ; Wenxia LI
Orthopedic Journal of China 2006;0(01):-
[Objective]To investigate Y-shaped osteotomy and the internal fixation with geese-head steel plates for treatment of congenital coxa vara.[Method]Lesser subtrochanteric and greater laterotrochanteric osteotomy were performed for 7 cases(9 hips)of congenital coxa vara with the Y-shaped osteotomy line.The distal femoral section met the lateral greater trochanteric section,fixed with geese-head steel plates.[Result]The cases were followed up for 1~5 years(averaged 3.6 years).According to Shi Yingqi's evaluation,4 hips were excellent,4 good and 1 fair.[Conclusion]The Y-shaped osteotomy and internal fixation with geese-head steel plates can improve the abnormal structure of upper femur,increase the real length of the affected limb.Therefore,it is an ideal effective method for treatment of congenital coxa vara.
6.Relations Between Autonomy and Social Adjustment of College Students
Caina LI ; Shasha QIU ; Wenxia WANG
Chinese Journal of Clinical Psychology 2006;0(06):-
Objective:The research investigated the characters of college students' autonomy and its relation to social adjustment.Methods:650 college students from Xi'an completed The Self-Regulatory Questionnaire and The Chinese College Student Adjustment Scale (CCSAS).Results:① Boys' autonomy level was higher than girls';There were no significant differences of autonomy level in the first three years of college,but the senior year appeared a slight reduction.②There were significant correlations between autonomy and social adjustment.③Students with higher autonomy had significant better social adjustment than lower autonomy students.④ Autonomy had direct effect on social adjustment.Conclusion:There are significant correlations between autonomy and social adjustment.
7.Complication in Infusion Therapy for Elders:Cause and Nursing Methods
Yuhua GAO ; Ping WANG ; Wenxia LI
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To probe how to avoid the complication after intravenous infusion for the elders. METHODS The cause of the complication in infusion therapy for the elders with a total of 80 cases in the past three years was analyzed retrospectively. RESULTS Among the complications after intravenous infusion for 80 elders,leakage injury accounted for 47 cases(58.5%), and phlebitis accounted for 21 cases(26.8%),respectively. CONCLUSIONS As the elders′ blood vessel wall is very thin,the intravenous infusion often causes injury,the nurses should pay more attention to operating of intravenous infusion for the elders,observing regularly,and prolonging the time for pressing the pinprick after pulling out the dropper,in order to reduce the coming of injury.
8.Early rehabilitation and intensity-time curve examine in peripheral facial paralysis
Xiaowen LI ; Guimin FU ; Wenxia CHEN
Chinese Journal of Rehabilitation Theory and Practice 2005;11(1):61-62
ObjectiveTo observe the therapeutic effect of early comprehensive rehabilitation and the value of intensity time (I/t) curve examine for peripheral facial paralysis.Methods89 patients with peripheral facial paralysis were treated by early comprehensive rehabilitation program in 1 week and were examined by I/t curve in 10~20 days.ResultsThe rate of the cure and excellent was 93.26%.Normal nerve detected by I/t curve were 62.92% and partial denervation were 37.08%.ConclusionPatients with peripheral facial paralysis who were treated by early comprehensive rehabilitation will have good prognosis. As a kind of examine ways, I/t curve can be used in clinic.
9.Protection against Myocardial Ischemia/Reperfusion Injury in Rats by Pretreatment with Paeoniflorin
Wenxia LIU ; Junlian SHU ; Li XU ; Junping CAO ; Yi MA
China Pharmacist 2015;(6):926-928
Objective:To investigate the protective effects of paeoniflorin on myocardial ischemia/reperfusion ( MI/R) injury in rats. Methods:The rat model of MI/R injury was prepared by coronary artery ligation for 30 min followed by 2-hour reperfusion. Then the rats were randomly divided into 5 groups:sham group, model group, paeoniflorin group respectively at high, medium and low dose (20, 10 and 5 mg·kg-1, n=10). Paeoniflorin was respectively injected via tail vein 1 h before the operation and at the beginning of the reperfusion. The CK, LDH and SOD activities and MDA contents in serum of rats were examined, and the area of myocardial in-farction was also calculated after the reperfusion. Results:Paeoniflorin (20 and 10 mg·kg-1 ) could significantly reduce the area of myocardial infarction when compared with the model group (P<0. 05). Paeoniflorin could obviously inhibit the CK and LDH activities (P<0. 05 or P<0. 01) and enhance the SOD activity (P<0. 01) in serum of MI/R rats. The MDA content in paeoniflorin groups at high and medium dose was significantly lower than that in the model group (P<0. 05). Conclusion:Paeoniflorin pretreatment shows effectiveness against MI/R injury, which may be associated with the inhibition of lipid peroxidation.
10.Study on Medication Rules of TCM Treatment for Primary Hepatic Carcinoma in Recent ;Ten Years
Minghao LIU ; Keke LI ; Lihui ZHANG ; Hanting JIA ; Wenxia ZHAO
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(9):45-47
Objective To analyze medication rules of TCM treatment for primary hepatic carcinoma in recent ten years;To provide references for clinical medication. Methods Literature about primary hepatic carcinoma in CNKI, VIP and Wanfang database from January 2005 to September 2015 was searched by computers to carry out statistical analysis of medicine classification and frequency of usage. Results Through screening, 131 articles were included, covering 131 compound TCM prescriptions, 228 kinds of medicine, and 1416 times of frequency of usage. Medicines with relatively high frequency were tonifying deficiency medicine 430 times (30.37%), damp-clearing medicine 233 times (16.45%), medicine for invigorating blood circulation and eliminating stasis (12.99%). Medicines with relatively high frequency were Atractylodis Macrocephalae Rhizoma 64 times (4.52%), Poria 62 times (4.38%), Glycyrrhizae Radix et Rhizoma 52 times (3.67%), Bupleuri Radix 49 times (3.46%), Paeoniae Radix Alba 45 times (3.18%), Astragali Radix 44 times (3.22%), Curcumae Rhizoma 43 times (3.04%), and Artemisiae Scopariae Herba 41 times (2.90%). Conclusion This study summarizes the medicine classification and frequency of usage of TCM treatment for primary hepatic carcinoma in recent ten years, which can provide data support for clinical treatment.