1.A study on the relationship between ultrasonography of dorsalis pedis artery and hemorheology in patients with diabetic foot
Xiaoming LIU ; Wenwei CHEN ; Hua SHI ; Ruiqiang GUO ; Yougang SUN
Chinese Journal of Ultrasonography 1997;0(06):-
Objective To study the relationship between ultrasonography of arteria dorsalis pedis and Hemorheology in patient with diabetic foot.Methods According to with or without frank anabrosis,51 patients were devided into two sub-groups:anabrosis group (23 patients) and no-anabrosis group (28 patients).The correlativity was analysed between the parameters of ultrasonography in arteria dorsalis pedis and hemorheological indices on patients with diabetic foot.Results When compared to patients without ulcers,vascular inner diameter (D),peak systolic velocity (PSV),resistent index (RI) and pulsatility index (PI) on patients with frank anabrosis were decreased significantly,but whole blood viscosity at high shear rate (BVH),whole blood viscosity at low shear rate (BVL),plasma viscosity (PV),fibrinogen (Fib) were increased.Multiple regression analyses indicated that the relationship between BVH,BVL and D was presence,partial regression coefficient (r) was -0.004 and -0.009 ; the relationship between PSV and BVH,PV was intimate,r was -0.957 and -25.655 ; the relationship between RI and BVH,PI and BVH,PV,Fib were relatively intimate,r was -0.009 , -0.141 , -2.666 , -0.383 ,respectively.Conclusions The changes of hemorheology can aggravate the abnormality of hemodynamics and the degree of vascular lesion in small vessels of lower limb,so it is one of influencing factor leading to lower limb arterial ischaemia and diabetic foot deterioration.
2.Application of Cluster Analysis Method to the Establishment of Rapid Dispensing Area in Automated Phar-macy
Wenqing WANG ; Jin LIU ; Hongye GUO ; Huijun GUO ; Wenwei DU ; Peihong LI
China Pharmacy 2015;(22):3115-3117,3118
OBJECTIVE:To optimize the placement of extra-machine medicines in the automated pharmacy and establish a ra-pid dispensing area to shorten medicine dispensing time. METHODS:12 588 prescriptions made within one week were collected from the outpatient pharmacy of our hospital,in which 29 kinds of extra-machine medicines used frequently were clustered on the basis of Pearson correlation coefficients. The extra-machine medicines used at a higher frequency were arranged in the storage posi-tions near to the medicine dispensing window,and those related to the above-mentioned medicines were stored in the positions adja-cent to them,thereby a rapid dispensing area was established. The effect of the above-said method was evaluated by comparing the time it took for the pharmacist to dispense medicines one week before and after the establishment of the rapid dispensing area. RE-SULTS:29 kinds of extra-machine medicines were clustered into 4 major categories,and stored in 4 positions in the rapid med-icine dispensing area respectively,and then the position codes were assigned. After the rapid dispensing area was established,the average single prescription dispensing time for the pharmacist decreased by about 9 s (40.43 s vs. 31.43 s,P<0.01). CONCLU-SIONS:The establishment of the rapid dispensing area based on cluster analysis method has increased the efficiency of dispensing medicines in the outpatient pharmacy of our hospital.
3.Infection status of Toxoplasma gondii and its related knowledge and behav-ior among special population in Changzhou City
Yanli GUO ; Yiqing XIE ; Yonggen ZOU ; Dacheng XU ; Wenwei XU ; Yang DAI ; Mingxue SHEN
Chinese Journal of Schistosomiasis Control 2017;29(4):498-501
Objective To investigate the prevalence of Toxoplasma gondii infection and related knowledge and behavior among special population in Changzhou City,so as to provide the evidence for formulating effective measures of toxoplasmosis prevention. Methods The pregnant women and patients with neoplasia in Changzhou hospitals,and livestock and poultry breeding or processing workers were selected as the subjects of the study. Venous blood samples were collected from each partici-pant for detecting IgG and IgM antibodies against T. gondii by ELISA. A questionnaire investigation on knowledge and behavior about T. gondii infection was conducted. Results Among the total 300 respondents investigated from March to May,2015,the prevalence of T. gondii infection was 16.3%(49/300). Totally 52 respondents knew the knowledge about the prevention and con-trol of T. gondii infection with an awareness rate of 17.3%(52/300). The proportion of participants who frequently contacted with cats/dogs(25.0%,13/52)in the group who knew the knowledge about the prevention and control of T. gondii infection was lower than that of participants(50.8%,126/248)in the group who did not know the knowledge about the prevention and control of T. gondii infection,and the difference was statistically significant(X2=11.51,P<0.05). The proportion of participants sepa-rating chopping boards for raw and cooked food(61.5%,32/52)in the group who knew the knowledge about the prevention and control of T. gondii infection was statistically higher than that of the participants(9.3%,23/248)in the group who did not know the knowledge about the prevention and control of T. gondii infection,and the difference was statistically significant (X2=78.43,P<0.001). There was a negative correlation between the awareness rate of the knowledge about the prevention and con-trol of T. gondii infection and the infection rate of T. gondii. The infection rate of T. gondii(5.8%,3/52)in the group who knew the knowledge about the prevention and control of T. gondii infection was lower than that(18.5%,46/248)of the group who did not know the knowledge about the prevention and control of T. gondii infection,and the difference was statistically significant (X2=5.14,P<0.05). Conclusions The awareness rate of the knowledge about the prevention and control of T. gondii infec-tion among special population in Changzhou City is low. The health education on the knowledge of the prevention and control of toxoplasmosis should be strengthened,in order to improve the awareness of personal hygiene and change the unhealthy lifestyles and dietary habits.
4.Clinical Observation of Comprehensive Chinese Medicine Therapy for Salvage Treatment of Sudden Deafness
Zuwei CAO ; Fengjuan YUE ; Huamin GUO ; Wenwei CAI ; Peng LIU ; Weiping HE
Journal of Guangzhou University of Traditional Chinese Medicine 2015;(3):423-425,429
Objective To evaluate the effect on salvage treatment of sudden deafness with comprehensive Chinese medicine therapy. Methods Fifty-three sudden deafness patients failing in conventional western medicine treatment were given comprehensive Chinese medicine therapy, and the salvage treatment followed by oral use of Chinese medicine, intravenous injection of Chinese patent medicine, acupoint injection, ear acupoint plastering, acupoint application, acupuncture, sound healing, and massage. The therapeutic effect and the relief of major accompanying symptoms were evaluated after treatment, and the relationship of disease course with clinical efficacy was also investigated. Results (1) After treatment, 4 cases were cured, 9 were markedly effective, 13 were effective, 27 were ineffective, and the total effective rate was 49.06%. (2) Except for the 2 excluded cases, the major accompanying symptoms such as tinnitus, auricular distress, and vertigo were relieved to various degrees in other cases. ( 3) Twenty-two patients had a course of disease within 14 days, and the total effective rate for them was 72.73%. A total effective rate of 32.26% was achieved in 31 cases with disease course over 14 days. It is indicated that the therapeutic effect for patients with a disease course less than 14 days was superior to that with a disease course over 14 days (P<0.01). Conclusion Comprehensive Chinese medicine therapy exerts inspiring therapeutic effect on salvage treatment of sudden deafness, and earlier intervention results into better effect.
5.Analyais of Toxoplasma gondii infection and related factors among special population in Changzhou City,Jiangsu Province
Yanli GUO ; Yonggen ZOU ; Dacheng XU ; Wenwei XU ; Yiqing XIE ; Yang DAI ; Mingxue SHEN
Chinese Journal of Schistosomiasis Control 2016;28(6):669-673,698
Objective To understand the prevalence of Toxoplasma gondii infection and related factors among special popu?lation in Changzhou City,so as to provide the evidence for formulating toxoplasmosis prevention measures. Methods The ve?nous blood was collected from participants in Changzhou City for detecting IgG and IgM antibodies against T. gondii by ELISA;and an epidemiological questionnaire investigation was also conducted. Results Among the total 400 respondents detected,the prevalence of T. gondii infection was 15.0%and the positive rates of IgG and IgM were 15.0%and 0.8%,respectively. The T. gondii infection rates of pregnant women,HIV/AIDS patients,patients with neoplasia,and livestock and poultry breeding and processing workers were 11.0%,11.0%,24.0%and 14.0%,respectively. As the age increased,the infection rate of T. gondii showed an upward trend,with the highest infection rate(21.6%)among the group of respondents aged above 50 years. The in?fection rates of groups with different education levels were statistically different(χ2=11.443,P<0.05),and there was a trend that the infection rate decreased with the increase of education level. The prevalence of T. gondii infection in pregnant women was not significantly associated with the number of pregnancies and gestational age. The infection rate of T. gondii in the live?stock and poultry breeding and processing workers increased with the length of their working years. Conclusions The preva?lence of T. gondii infection among the special population in Changzhou City is high. Therefore,it is necessary to enhance the health education on the knowledge and information of prevention and control of toxoplasmosis,and to improve the awareness of personal protection,the hygiene practices and diet habits. In addition,more attention should be paid to T. gondii monitoring in the special population.
6.A community-based survey in awareness of osteoporosis and influence factors in middle-aged and old population in Guangzhou
Xinfeng GUO ; Wanxin WEN ; Shaonan LIU ; Lihong YANG ; Huimin CAI ; Wenwei OUYANG ; Zhijiang FU ; Zhian CHENG
The Journal of Practical Medicine 2015;(20):3430-3433
Objective To investigate the awareness of osteoporosis and its influential factors in middle-aged and older people. Methods By using self-designed questionnaire, 354 middle-aged and old people were investigated as to their awarness of osteoporosis in Chajiao street community in Guangzhou. Among them, 58 people were measured the bone density in the calcaneal bone by Ultrasound. Results The average score of the questionnaire was 9.46 ± 5.13, and the accuracy was 39.4%. In the diagnosis and treatment, the accuracy was just 17.8%. The diet (the accuracy in 54%) and sport (the accuracy in 50.3%) were good. The statistical analyses showed the linear relationship between the T value of bone density and the age (P = 0.021), between the T value and the score (P = 0.047). Wilcoxon rank sum test found that the T value between female and male was significantly different (Z = -3.749, P < 0.000). With multiple linear regression analysis, the T value had a linear correlation with the score (F = 4.224, P = 0.045) positively. Conclusions Currently, the awareness of osteoporosis in the middle-aged and old people was inadequate. To better prevent osteoporosis, the propogation of knowledge and guidance provided by clinicians in osteoporosis should be improved necessarily and emergently.
7.CT differential diagnostic value of small bowel wall thickness and density changes in small bowel obstruction
Ting ZHANG ; Tianchang GUO ; Caiyun WU ; Wenwei YE ; Dasheng XU ; Keguo ZHENG
Chinese Journal of Radiology 2014;48(4):299-302
Objective To investigate the CT diagnostic value of small bowel wall thickness and density in differentiating simple small bowel obstruction (SI) from strangulative small bowel obstruction (ST).Methods Fifty-three cases with thickened small bowel wall (thickness > 3 mm) confirmed on CT scan were reviewed,including 27 cases of SI and 26 cases of ST,in conjunction with their proven intraoperational,pathological and clinical findings.Of the 53 cases,35 cases also underwent postcontrast CT scan.CT manifestations of relationships between thickened small bowel wall and its density were classified as normal,higher or lower density in tunica mucosa of small bowel wall,higher or lower density in full thickness of small bowel wall for exploring the differential diagnostic features between SI and ST on CT scan.Chi-square or Fisher exact test were used to test the proportion difference of CT scan between SI and ST.Results In cases with normal density in tunica mucosa (NDTM) on precontrast CT,there were 21 cases of SI and 6 cases of ST(x2 =15.859,P <0.01).However,in cases with NDTM on postcontrast CT,there were 13 cases of SI and 5 cases of ST,and there was no significant difference (x2 =1.377,P > 0.05).Thus,NDTM showed no convincing value in differentiating SI from ST.In cases with lower density in tunica mucosa (LDTM) on precontrast CT,there were 4 cases of SI and 5 cases of ST (P > 0.05).In cases with LDTM on postcontrast CT,there were 4 cases of SI and 4 cases of ST (P > 0.05).Thus,LDTM also showed no value in differentiating SI from ST.The lower density in full thickness of small bowel wall (LDFTS) was revealed in 0 of SI and 10 cases of ST on precontrast CT (P < 0.01),and 0 of SI and 5 cases of ST on postcontrast CT (P < 0.01),indicating that LDFTS showed significant value in differentiating SI from ST.Conclusion Combining the small bowel wall thickness and density,CT manifestations of early bowel wall pathological changes in small bowel obstruction can be acquired,adding some value in the differential diagnosis between SI and ST.
8.Factors Inlfuencing Shear Wave Velocity by Using Elasiticity Imaging Technique
Long YANG ; Jianjun YUAN ; Qi WANG ; Gang WU ; Wenqing GUO ; Wenwei WANG ; Bing ZHAO
Chinese Journal of Medical Imaging 2014;(9):697-700
Purpose To investigate the influence on shear wave velocity (SWV) by different probe frequency, scanline angle and ROI depth. Materials and Methods The elasticity QA Phantoms was used in the study. First the SWV was measured by curve probe at depths of 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, 6 cm, 7 cm and 8 cm. The scanline angle changed from 0°from midline, 1°-15°, 16°-30°and 31°-45°. Then the SWV was measured again by using line probe at depths of 1 cm, 2 cm, 3 cm and 4 cm. The measured data were analyzed statistically. Results The SWV showed difference by using the two probes (P<0.05). As depth increased, the measurement by curve probe changed from overestimate to underestimate, while the measurement by line probe always showed underestimate from standard value. When the curve probe was used, the angle and depth affected SWV interactively (F=85.87 and 35.96, P<0.01), and had interactive effects (F=17.63, P<0.01). When the scanline angle was within 15°, the angle had little inlfuence upon the measurement. When the scanline angle was 0 °, the measurement was the closest to the standard value at the depth of 4 cm, and the maximum deviation occurred at the depth of 5 cm. The inlfuence of depth upon measurement had signiifcant difference when the line probe was used (P<0.05). The measurement was the closest to the standard value at the depth of 1 cm, and the maximum deviation occurred at the depth of 4 cm. Conclusion Factors like probe frequency, scanline angle and ROI depth can affect the SWV. When the curve probe is used, the accurate measurement occurs at the depth of 4 cm when the scanline angle is within 15°. When the line probe is used, the accurate measurement occurs at the depth of 1 cm.
9.The internal mandibular lengthening eevice of type MS - 1 in an experimental study: a preliminary report
Xiaofeng CHANG ; Xiaoming GU ; Wenwei GUO
Chinese Journal of Plastic Surgery 2001;17(2):90-92
Objective To introduce the new type of MS - 1 internal mandibular distracter and its applications and to investigate the advantage or disadvantage of the device through an experimental study in dogs.Methods 15 dogs were subjected to unilateral or bilateral mandibular lengthening using the MS- 1 internal mandibular distracter. Photography, tooth casting, general measurement, X-ray and hisological examinations were conducted to observe new bone formation and mineralization at the bony gap at various times of distraction. Results The amount of mandibular lengthening reached to nearly 98% of the designed value in all animals except for one. Breaking or corrosion of the material was not discovered within the whole experimental period.The created bony gap was filled up with woven trabecular bone while some cartilage islands occurred in only 3 dogs. Conclusions The MS - 1 mandibular distracter has unique structural traits and advantages over the external one, such as precision of elongation. It may become a new access to treat mandibular deformities in the future.
10.The internal mandibular lengthening eevice of type MS - 1 in an experimental study: a preliminary report
Xiaofeng CHANG ; Xiaoming GU ; Wenwei GUO
Chinese Journal of Plastic Surgery 2001;17(2):90-92
Objective To introduce the new type of MS - 1 internal mandibular distracter and its applications and to investigate the advantage or disadvantage of the device through an experimental study in dogs.Methods 15 dogs were subjected to unilateral or bilateral mandibular lengthening using the MS- 1 internal mandibular distracter. Photography, tooth casting, general measurement, X-ray and hisological examinations were conducted to observe new bone formation and mineralization at the bony gap at various times of distraction. Results The amount of mandibular lengthening reached to nearly 98% of the designed value in all animals except for one. Breaking or corrosion of the material was not discovered within the whole experimental period.The created bony gap was filled up with woven trabecular bone while some cartilage islands occurred in only 3 dogs. Conclusions The MS - 1 mandibular distracter has unique structural traits and advantages over the external one, such as precision of elongation. It may become a new access to treat mandibular deformities in the future.