ObjectiveTo investigate the risk of cerebral infarction on pat ients with transient ischemicattack (TIA) by combining ABCD2 score and three imaging methods.MethodsFive hundred and seventy-eight patients with TIA visiting our hospital from January 2007 to December 2011 were assessed for the risk of cerebral infarction after TIA by ABCD2 score method,magnetic resonance diffusion weighted imaging (DWI),magnetic resonance angiography (MRA) and carotid artery color Doppler imaging (CDFI).Cases were followed up on 2 d,7 d and 30 d for incidence of cerebral infarction.ResultsCerebral infarction occurred in 37 cases (6.40％),47 cases ( 8.13％ ) and 61 cases ( 10.55％ ) on day 2,day 7 and day 30.The occurrence of cerebral infarction after TIA in high risk group (35 cases ) by single ABCD2 score was found in 15 cases (42.86％ ),18 cases (51.43％) and 21 cases (60.00％) on day 2,day 7 and day 30.Twenty-eight cases (54.90％),31cases (60.78％ ),and 38 cases (74.51％ ) of patients after TIA with ABCD2 ＞ 3 and DWI positivity (51cases) suffered cerebral infarction on day 2,day 7 and day 30.Cerebral infarction occurred in 22 cases (61.11％),24 cases (66.67％ ) and 30 cases (83.33％) of patients with ABCD2 ＞ 3 points and cerebral artery stenosis (36 cases) on day 2,day 7 and day 30 after TIA.The occurrence of cerebral infarction after TIA on day 2,day 7 and day 30 were in 21 cases ( 60.00％ ),23 cases ( 65.71％ ),28 cases ( 80.00％ ) of the patients with ABCD2 ＞ 3 points and the carotid artery atheroma-caused bureaucratic stenosis (35 cases).There were no significant difference in the value of three methods to assess the risk of cerebral infarction in high-risk TIA groups (P ＞ 0.05).ConclusionTIA patients can progress to cerebral infarction in the short term.There are some predictive value by ABCD2 score from 2 to 30 days for cerebral infarction occurring after TIA,but it is only a simple clinical assessment method.ABCD2 score ＞ 3 points must be combined with DWI,MRA,and other tests in high-risk patients to identify the risk of cerebral infarction,thus improving the accuracy of the prediction.The combined evaluation of TIA patients will help the clinicians give better treatment and decision to this group of patients

Objective To investigate the timing and security of oral glucose tolerance test (OGTT) in patients with acute coronary syndrome (ACS).Methods Two hundred and thirty-two hospitalized patients with ACS were collected from Jan.2007 to Jan.2012.OGTT was undergone in a stable condition at 3 months after being discharged,noting ECG and change of symptoms in patients.Results There was no significant difference in test results of proportions of patients with normal blood sugar [40.95％ (95/232) vs.39.91％ (89/215),x2 =0.051,P ＞ 0.05 ],diabetes [ 25.00％ (58/232) vs.22.33％ (48/215),x2 =0.032,P ＞ 0.05 ],impaired glucose tolerance [ 34.05％ (79/232) vs.33.95％ ( 73/215 ),x2 =0.001,P ＞ 0.05 ],and impaired fasting glucose [2.59％ (6/232) vs.2.33％ (5/215),x2 =0.441,P ＞0.05 ] at 3 months after discharge compared with before discharge when patients were in stable conditions.No significant difference was found on ST segment ECG [ (-0.12 ±0.08 ) mV vs.(-0.15 ± 0.12) mV,t =0.23,P =0.85].Adverse symptoms were not found during the OGTT examination.Conclusion Patients with ACS have a high risk of abnormal glucose metabolism.Undergoing OGTT is safe for stable status patients with ACS.OGTT should be conducted as the routine exam.Early detection and appropriate intervention and treatment are necessary for patients with abnormal glucose metabolism.

Purpose To investigate the clinical and pathological features of inflammatory fibroid polyps ( IFPs) and to discuss its diag-nosis, differential diagnosis and treatment. Methods Clinicopathological data of 14 cases of IFPs were collected and analyzed retro-spectively. Results Most of the 14 cases were found to have submucosal polyps of the digestive tract protruding growing into the cavi-ty. Perivascular onion skinning which formed by spindle fibrocytes around vascular proliferation and eosinophilic inflammatory infiltrates were present as the characteristic feature of lesions. ABC results demonstrated that the lesions showed fibroblastic, myofibroblastic and dendritic cell signs. Conclusions IFPs are rare, benign tumors that can arise throughout the digestive tract, with unique histological changes in pathology. Surgical excision or endoscopic removal is the main treatment.

Objective To investigate the expression of KLF4 in cervical carcinoma and its significance. Methods Immunohistochemistry and tissue microarray were used to examine the expression of KLF4 in 39 cases of carcinoma, 30 cases of normal cervical epithelial tissues and 28 cases of cervical cancer in situ. Results Moderate to strong nuclear staining for KLF4 was found in normal tissues and cervical cancer in situ. Interestingly, KLF4 expression was lost in 16 (P<0.05) of 39 carcinoma cases. However, KLF4 expression was not associated with clinicopathologic parameters, including tumor stage and differentiation. Conclusion Our observations indicate that KLF4 may function as a tumor suppressor in the pathogenesis of cervical cancer.

Objective:To establish early warning mechanism for enhancing the using effect of multimedia and guaranteeing quality of teaching so as to satisfy the requirement of morphology course for definition of multimedia in medical college.Methods: The archive of each multimedia equipment was established and the service times of main components and parts which existed fault were analyzed, and the anticipative occurrence time of fault was pre-deduced. And the early prevention and early detection were implemented in the early warning mechanism.Results: The each multimedia equipment could achieved optimal situation for usage, and got rid of the poor effect when equipment was normal.Conclusion: The warning management of life cycle can fast decrease fault rate and effectively reduce the maintenance cost. Therefore, the mechanism can guarantee the teaching quality of medical college and enhance the satisfaction of teachers and students.

Objective: To investigate the level and influencing factors of health literacy among the elderly in Gannan Tibetan Autonomous Prefecture, Gansu Province, so as to provide the evidence for developing the strategy to improve health literacy among the elderly. Methods: A total of 3 125 residents at ages of 60 years and older were recruited from Gannan Tibetan Autonomous Prefecture with a multistage random cluster sampling method from June to September, 2021. The level of health literacy was investigate among the elderly using the Questionnaire on the Health Literacy among Chinese Residents, and factors affecting the health literacy were identified using a multivariable logistic regression model. Results: A total of 3 125 questionnaires were allocated and 3 022 valid questionnaires were recovered, with an effective recovery rate of 96.70%. The respondents included 1 562 men (51.69%) and 1 460 women (48.31%), and had a mean age of (67.37±5.78) years. The participants included 1 234 individuals with an ethnic minority (40.83%). The overall prevalence of health literacy was 5.99% among participants, and the prevalence rates of basic healthy knowledge and attitudes, healthy lifestyles and behaviors and basic health-related skills were 13.57%, 8.97% and 7.67%, respectively. Multivariable logistic regression analysis identified Han Ethnicity (OR=2.266, 95%CI: 1.497-3.431), educational level (illiteracy/semi-illiteracy, OR=0.097, 95%CI: 0.038-0.246; primary school, OR=0.125, 95%CI: 0.051-0.303; junior high school, OR=0.276, 95%CI: 0.113-0.672; high school/vocational high school/technical secondary school, OR=0.307, 95%CI: 0.125-0.757), enterprise workers (OR=1.791, 95%CI: 1.089-2.947) and annual household income of less than 10 000 RMB (OR=0.526, 95%CI: 0.294-0.940) as factors affecting health literacy among the elderly in Gannan Tibetan Autonomous Prefecture. Conclusions The level of health literacy is low among the elderly in Gannan Tibetan Autonomous Prefecture, and ethnicity, educational level, occupation and annual household income are main factors affecting the level of health literacy among the elderly in Gannan Tibetan Autonomous Prefecture.

Objective To observe the effects of acupuncture on stroke in stroke unit, and its cost-effectiveness. Methods60 patients were divided into control group (n=30) and treatment group (n=30). All the patients were treated with structural therapy known as stroke unit, and the treatment group accepted acupuncture in addition. They were assessed with National Institutes of Health Stroke scale (NIHSS) and Barthel Index (BI) before, 15 d and 30 d after treatment. Their expenses for hospital were investigated. ResultsThe scores of NIHSS and BI improved in the treatment group compared with those in control group (P<0.05) 15 d and 30 d after treatment. The average cost for a score improved in both NIHSS and BI was less in the treatment group than in the control group (P<0.05). ConclusionThe acupuncture applied in stroke unit is effective and economical for stroke patients.

We applied a new teaching mode,combining problem-based learning (PBL) with extended teaching in clinical internship and case discussion,in order to adapt to the new situation in infectious diseases.The teaching efficacy was evaluated by questionnaire and classroom effect.The results showed that the new mode cultivated the students' self-learning ability and broadened their professional perspective.

Objective To determine the moisture in Huodan pills by near-infrared spectroscopy. Methods At the beginning,water content of 174 samples were determined and all data of samples about near-infrared spectrum were collected. And then all the data were pretreated by first-derivative and Savitzky-Golay filter. At last,the NIR quantitative model for moisture in huodan pills was established by partial least squares regression and validated by the validation set. Results The correlation coefficients,the root mean square error overall of calibration, that of cross validation of the calibration model was 0. 988 17, 0. 103,and 0. 326 16,respectively. The root mean square error overall of prediction and the average recovery of validation was 0. 217 and 98. 02%. Conclusion The NIR spectroscopy analysis model is steady,accurate and reliable,which can be used to detecte moisture content of huodan pills.

Objective To study the life quality and influencing factors for empty nester elderly in rural area in Hunan,and to provide the scientific basis for the effective interventions.Methods The two villages of Yiyang and Huaihua were randomly selected by cluster sampling from June 2011 to December 2011 in Hunan.Data of the world health organizations quality of life instrument-short version (WHOQOL-BREF) was collected by face to face interview with the empty nesters.The risk factors for the quality of life in empty nester elderly in rural area were analyzed by the multiple linear regression analysis.Results A total of 785 valid questionnaires were acquired,among which 472 cases were from empty nester elderly (60.1％,472/785),the average age of them was (69.3±7.3) years,and the male:female ratio was 1.1:1 (250:222).The literacy of 81.8％ of empty nester elderly were under junior middle school,69.7％ of them married with consorts who were still living,74.4％ of them were farmer,75.2％ of them had monthly income under 500 Yuan,56.4％ of them got the income from their own labor,69.9％ of them considered that their relationship with children were harmony.64.2 ％ of empty nester elderly in village suffered from chronic diseases and 16.7 ％ of them suffered from accidental injury within the last one year.The scores in physiological health,psychological health and quality of life were lower in empty nester elderly than in the non-empty nester elderly [(60.8±15.7) vs.(63.1±13.5),(59.0±12.1) w (64.6±17.4),(59.5±9.8) vs.(63.0 ± 10.1),t=3.18,4.43,4.91,all P＜0.05].The multiple linear regression analysis showed that the influencing factors for quality of life in empty nester elderly were education background,marital status,source of finance,relationship with children,chronic disease and accidental injury within the last one year (β=1.693,2.426,0.779,1.060,-7.007,-3.784,all P＜0.05).Conclusions The empty-nest elderly accounts for more than half of the elderly in rural area,who have the lower levels in physio-psychological health and quality of life.We should improve their awareness and knowledge of health,build their harmonious relationship with spouse and children,improve the social security and medical insurance system,actively promote the knowledge of chronic disease and accidental injury,in order to improve the quality of life in empty nester elderly and achieve the healthy aging.