Objective To evaluate the curative effect of transurethral electrosection for the treatment of bladder neck sclerosis in senile patients. Methods Clinical data of 36 aged patients with bladder neck sclerosis treated by transurethral electrosection in this hospital from February to September, 2000, were reviewed. The curative effect was evaluated according to the improvement of dysuria, residual urine volume (RUV) and Qmax before and after the surgery. Results Follow-up for 3～18 months (mean, 7 months) in 30 patients showed an effective rate of 86.7% (26/30) and no severe complications. Conclusions Transurethral electrosection is an effective alternative for bladder neck sclerosis in senile men.

Objective To verify the mechanism of Buyang Huanwu decoction in the treatment of spinal cord injury based on network pharmacology and molecular docking.Methods The active ingredients and targets of Buyang Huanwu decoction were screened out by TCMSP,SymMap,PubChem and Swiss Target Prediction databases.Spinal cord injury targets were retrieved from OMIM,GeneCards,TTD,and DrugBank databases.Through venny software,the intersection target of Buyang Huanwu decoction and spinal cord injury was obtained.The active ingredient-target network for the treatment of spinal cord injury was constructed with Cytoscape software.Gene ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis of common targets were carried out by DAVID,and the binding ability of drugs and targets was analyzed by molecular docking technology.Results A total of 106 active ingredients and 225 targets of Buyang Huanwu decoction,1315 targets of spinal cord injury and 112 targets of drug-disease intersection were obtained.The active ingredients of Buyang Huanwu decoction were quercetin,kaempferol,ellagic acid,luteolin and hederagenin in the treatment of spinal cord injury.Conclusion Buyang Huanwu decoction can achieve the purpose of treating spinal cord injury through various signal pathways.