To define the definite diagnosis of dementia with Lewy bodies(DLB). Three cases of DLB diagnosed by bedside examination,cerebral image or pathology were analysed. These patients had been diagnosed as Alzheimer disease(AD) or AD with Parkinson disease (PD). DLB consisted of the following features as compared with AD:①Slow progressive congnitive decline, especially fluctuating congnitive defect was prominent;② Recurrent visual hallucinations that were typically well formed and detailed;③The extrapyramidal symptoms usually included mild rigidity and bradykinesia, and they almost appeared simultaneously in the extremities; ④Cerebral atrophy was relatively mild. The clinical diagnosis of DLB might be possible on the detailed basis of their peculiar features, but other neurodegeration disorders should be ruled out.

BACKGROUNDTracheal and carinal resection and reconstruction is an important way in treatment of lung cancer invading trachea and carina. The aim of this study is to summarize the method and effect of tracheal and carinal resection and reconstruction in treatment of lung cancer.

METHODSSeventy-three patients with lung cancer who underwent tracheal and carinal resection and reconstruction were retrospectively analyzed. There were 22 cases for right pneumonectomy and carinal resection, 14 cases for right pneumonectomy and tracheobronchoplastic procedure, 12 cases for right sleeve pneumonectomy, 15 cases for tracheobronchoplastic procedure plus right upper lobectomy, 2 cases for left sleeve pneumonectomy and 8 cases for left pneumonectomy and tracheobronchoplastic procedure.

RESULTSFour cases received palliative operation. Four patients (5.48%) died in the perioperative period. The 1-, 3-and 5-year survival rate was 75.3%, 63.0% and 23.3% respectively.

CONCLUSIONSCareful preoperative assessment, skillful operation and appropriate postoperative treatment are helpful to improve the outcome of tracheal and carinal resection and reconstruction for lung cancer.