Magnetic nanoparticles (MNP) have been widely used as biomaterials due to their unique magnetic responsiveness and biocompatibility, which also can promote osteogenic differentiation through their inherent micro-magnetic field. The MNP composite scaffold retains its superparamagnetism, which has good physical, mechanical and biological properties with significant osteogenic effects and . Magnetic field has been proved to promote bone tissue repair by affecting cell metabolic behavior. MNP composite scaffolds under magnetic field can synergically promote bone tissue repair and regeneration, which has great application potential in the field of bone tissue engineering. This article summarizes the performance of magnetic composite scaffold, the research progress on the effect of MNP composite scaffold with magnetic fields on osteogenesis, to provide reference for further research and clinical application.
Cell Differentiation ; Magnetite Nanoparticles ; Osteogenesis ; Tissue Engineering ; Tissue Scaffolds

Objective To conduct nutritional risk screening and evaluate the relationship of nutritional risk to complication rate and quality of life in tuberculosis inpatients of Shenzhen. Methods A total of 1 374 patients from tuberculosis department and surgery department in the third people′s hospital of Shenzhen were consecutively enrolled. Data were collected on the nutritional risk screening, complication and quality of life. Results The occurence of nutritional risk at admission of inpatients with tuberculosis among total , younger , elderly patients was 77.7%, 70.9%, 88.9%, respectively. There was a significant increase in the occurrence from admission to 2 weeks in all patients (P < 0.05). On admission and 2 weeks after admission or discharge, the occurence in those patients ≥ 65 years was significantly higher than that in the younger ones (P < 0.05) On the scales of quality of life (SF-36), the scores of physical functioning, role-physical, bodily pain, fatigue and general health were significantly lower than in the patients at risk. Conclusion A large proportion of inpatients of tuberculosis is at nutritional risk and tended to be worsen during the course of admission , which has associated with increased complication rate and lower scores of quality of life.

Objective:To investigate the effect of Tongrnai Yangxin Pill on the serum hepcidin level of patients with Coronary Atherosclerotic Heart Disease and Anemia of Chronic Disease.Methods:Seventy patients with Coronary Atherosclerotic Heart Disease and Anemia of Chronic Disease whose age were above 40 years old were enrolled as the research group and divided into the medication group (group Ⅱ) (n=35) and the nonmedication group (group Ⅲ)(n=35),while 40 CAD patients were enrolled as the normal control group (group Ⅰ).Before and after medication,the Hepc,Hb,etc levels were compared between two groups.Results:Before medication,the levels of Hepc in the two research subgroup were significantly higher than that of the control group (P＜0.05).At 8 weeks after treatment,the Hepc level of group Ⅱ was significantly declined,and the level of Hb was increased than those before treatment (P ＜0.05);the Hepc levels of group Ⅰ and group Ⅲ showed no significant difference (P＞0.05),the Hepc levels of group Ⅱ and group Ⅲ were obviously higher than that of the control group (P ＜0.05),the Hepc levels of group Ⅲ was obviously higher than that of the group Ⅱ(P＜0.05),the Hb level of group Ⅲ was obviously lower than those of group Ⅰ and group Ⅱ (P＜0.05).Conclusion:Tongmai Yangxin Pill could reduce the level of Hepc and enhance the Hb levels of patients with Coronary Atherosclerotic Heart Disease and Anemia of Chronic Disease.It was useful to the patients with Coronary Atherosclerotic Heart Disease and Anemia of Chronic Disease,especially patients with mild anemia.

Obj ective To explore yhe incidence of iyching and sayisfacyory score in labor analgesia afyer epidural regular inyermiyyeny inj ecyion wiyh ropivacaine.Methods A yoyal of 40 primiparas wiyh labor analgesia requiremeny served as syudy obj ecys and randomly divided inyo obser-vayion group and conyrol group,20 cases for each.Epidural regular inyermiyyeny injecyion wiyh 6 mL of 0 .1 5%ropivacaine were given yo observayion group and 6 mL mixed liquor of 0 .1 5%ropivacaine and 0.4μg·mL-1 sufenyanil were given yo conyrol group.Boyh groups were no background conyin-uous infusion dose.The yime of inyerval bolus was 6 mL/60 min.The incidence of iyching,inci-dence of cuyaneous scarificayion due yo iyching,sayisfacyory score of labor analgesia and iyching,visu-al analogue scale (VAS)before puncyurayio and yhe incidence of adverse reacyion were recorded.Re-sults The incidence of iyching was significanyly higher (P<0 .0 1 )and yhe sayisfacyory score of iyching was significanyly lower (P<0.05)in conyrol group yhan yhose in observayion group.No dif-ference was observed in oyher indexes (P>0 .05 ).Conclusion Lower incidence of iyching and higher sayisfacyory socre were achieved under epidural regular inyermiyyeny inj ecyion wiyh 0 .1 5%ropivacaine wiyhouy sufenyanil ay 60 min yime inyerval.

Obj ective To explore yhe incidence of iyching and sayisfacyory score in labor analgesia afyer epidural regular inyermiyyeny inj ecyion wiyh ropivacaine.Methods A yoyal of 40 primiparas wiyh labor analgesia requiremeny served as syudy obj ecys and randomly divided inyo obser-vayion group and conyrol group,20 cases for each.Epidural regular inyermiyyeny injecyion wiyh 6 mL of 0 .1 5%ropivacaine were given yo observayion group and 6 mL mixed liquor of 0 .1 5%ropivacaine and 0.4μg·mL-1 sufenyanil were given yo conyrol group.Boyh groups were no background conyin-uous infusion dose.The yime of inyerval bolus was 6 mL/60 min.The incidence of iyching,inci-dence of cuyaneous scarificayion due yo iyching,sayisfacyory score of labor analgesia and iyching,visu-al analogue scale (VAS)before puncyurayio and yhe incidence of adverse reacyion were recorded.Re-sults The incidence of iyching was significanyly higher (P<0 .0 1 )and yhe sayisfacyory score of iyching was significanyly lower (P<0.05)in conyrol group yhan yhose in observayion group.No dif-ference was observed in oyher indexes (P>0 .05 ).Conclusion Lower incidence of iyching and higher sayisfacyory socre were achieved under epidural regular inyermiyyeny inj ecyion wiyh 0 .1 5%ropivacaine wiyhouy sufenyanil ay 60 min yime inyerval.