Objective To evaluate the clinical efficacy of green light photoselective vaporization(PVP)combined testicular resection plus anti-androgen treatment on advanced prostate cancer and bladder outlet obstruction.Methods Twenty cases with PVP of advanced prostate cancer and bladder outlet obstruction were selected as our subjects,who underwent PVP testicular resection plus anti-androgen treatment.The clinical information was recorded.Results All patients were succeed through surgery.Maximum urinary flow rate (MFR) at the pre-operation was (2.0 ± 1.0) ml/s,and increased to (14.0 ± 4.5) ml/s after operation.Serum prostate specific antigen (PSA) was decreased from the preoperative (176.5 ± 160.5) μg/L to (2.0 ± 1.0)μg/L International prostate symptom score (IPSS) was from (25.0 ± 5.0) down to (8.0 ± 1.0) points.The quality of life (QOL) score was (4.0 ± 2.0) at pre-operation,higher than after operation (1.0 ± 1.0)points.There were significant differences between preoperative and postoperative (t =9.502,7.371,5.328,8.350,P ＜0.05).Every patient was followed up from 3 to 18 months.The improvements regarding of clinical symptoms were seen including voiding,and all patients survived with tumor.Conclusion Advanced prostate cancer associate with bladder outlet obstruction.The therapy plan of PVP joint testicular resection plus antiandrogen is proved to improve symptoms of urethral obstruction and patient quality of life.

Objective With the consummation of the medical insurance system, the working of medical insurance gets more and more important in the management of hospital. How to establish scientific and reasonable index of ration becomes one of the emphases and difficulty. Methods By using the data mining technology, the index of ration in medical treatment insurance system is constituted and the related dates are analyzed too. Results The technology of data mining can be made the dynamic index of ration, picked up the analysis feedback speed, as well as made promptly the analysis and recalls. Conclusion The technology of dates mining technology is introduced in quota management that will adapt the changes and challenges in the management of medical insurance.

With the higher and higher application level of medical information technology, the construction of digital hospital has been a trend in the field of medical information. Based on the opinions of domestic and foreign experts, this paper introduces the definition of digital hospital and analyzes different application levels in digital hospital. The key technology is discussed in detail.

OBJECTIVE:To study the effect and its mechanism of dexmedetomidine(Dex)on inflammatory response in septic mice. METHODS:Mice were randomly divided into normal control group,model group,miR-146a inhibitor (50 mg/kg)+Dex (50 μg/kg)group,Dex low-dose,medium-dose,high-dose groups(10,30,50 μg/kg),10 in each group. Except for normal con-trol group,other groups were intraperitoneally injected lipopolysaccharide to induce septic models,intraperitoneally injected rele-vant medicines after 0.5 h. After drug intervention for 6 h,miR-146a expression,IRAK1 and TRAF6 mRNA expressions in periph-eral blood mononuclear cells in each group were detected by real-time fluorescence quantitative polymerase chain reaction method. IRAK1,TRAF6 protein expressions in peripheral blood mononuclear cells in each group were detected by Western blot method. TNF-α,IL-6 levels in serum were detected by enzyme-linked immunosorbent method. RESULTS:Compared with normal control group,miR-146a expression,TNF-α and IL-6 levels,IRAK1,TRAF6 mRNA and protein expressions in peripheral blood mononu-clear cells in model group were increased(P<0.01). Compared with model group,miR-146a expression in peripheral blood mono-nuclear cells in Dex medium-dose,high-dose groups were increased;TNF-α and IL-6 levels,IRAK1,TRAF6 protein expressions were decreased (P<0.05 or P<0.01);while IRAK1,TRAF6 mRNA expressions changed less obviously (P>0.05). Compared with Dex high-dose group,miR-146a expression,in peripheral blood mononuclear cells in miR-146a inhibitor+Dex group was de-creased;TNF-α and IL-6 levels,IRAK1,TRAF6 protein expressions were increased (P<0.05 or P<0.01);while IRAK1, TRAF6 mRNA expressions changed less obviously(P>0.05). CONCLUSIONS:Dex can inhibit the inflammatory response in sep-tic mice. The mechanism may associate with inducing miR-146a expression and inhibiting the 2 important adaptor proteins IRAK1, TRAF6 expressions in Toll-like receptor 4/nuclear factor-κB pathway.

Objective To evaluate the feasibility of transmitting a high definition video stream of medical images at a narrowband network.Methods The medical images and operation instructions were transmitted in a separate way, and the video streams were reconstructed by executing operations.Results The bidirectional transmitting model and the unidirectional transmitting model were designed. Both of them did well at a narrowband network.Conclusion Transmitting a high definition video stream of medical images at a narrowband network can be done based on the reappearing of operational order.

Objective To solve the new problems for quality assurance of PACS which imported by the use of PACS.Methods The medical imaging quality control system used between imaging modality and image acquisition gateway was designed.Results The medical imaging quality control system could partially solve the problem for quality assurance of PACS.Conclusion With the use of medical image quality control system,wrong or low quality image can be found and modified earlier.Therefore,the veracity of medical information and medical image of PACS can be improved farther.

Objective To resolve the sharing of the images which are dispersed in multiple mini-PACS in one hospital or in the distributed PACS in the different hospitals.Methods The grid technology and the medical image network were integrated to research some key technologies on a medical image storage grid.Results Basing on the services provided by grid and considering the hospital's situation,two layers architecture of storage grid that was adapted with the sharing character of the medical information were put forward.Using the services provided by the storage grid,the dynamic storage extension was realized.Conclusion The medical image storage grid can integrate multiple storage systems in the image network.It supports the effective usage of the storage system and transparent accessing for users.

Throughputs of 802.11g wireless LAN in different distances and different modes were measured,as well as the real throughputs of medical images using PACS software.Main problems and the promising future of using 802.11g wireless LAN in PACS are discussed.

DICOM acquisition gateway,the strobe of PACS date flow,is a key element of PACS.But on the process of acquisition,the images sometimes might be lost.This paper will focus on the image recovery scheme of DICOM acquisition gateuay in the notion of image missing.

Objective: To ensure the integrity、non-repudiation、authenticity of pictures and relevent messages by making a digital signature for a DICOM file. Methods: By using OpenSSL toolkits and dcmsign of DCMTK toolkits, make a digital sig nature for the relevent messages of DICOM medical image and then save it behind of the DICOM file. Results: We can evaluate integrity、non-repudiation、authenticity of pictures and relevent messages in the DICOM file which has been made a digital signature. Conclusion: To make a digital signature in a DICOM file by using the OpenSSL toolkits and dcmsign of DCMTK toolkits can realize the security when DICOM file transported in remote medical treatment and PACS.