OBJECTIVE:To evaluate the effect of pharmaceutical care (PC) program on hypotension. METHODS: The pertinent literature from January 1999 to February 2008 was retrieved from Medline, EMBASE, Cochrane, CNKI, CBM and other databases, and the randomized controlled trials (RCTs) with the intervention measures of PC were collected. The literature retrieving and screening were done respectively by 2 statistical clerks. A meta-analysis of the data was conducted by using the Review Manager 4.2 software. RESULTS: A total of 5 RCTs with 585 hypertension patients were included in this Meta analysis. Compared with the control group, the PC program intervention group had significantly lower systolic blood pressure (SBP) and diastolic blood pressure (DBP) after follow-up; and the SBP and DBP had a much better improvement in the intervention group than in the control group. CONCLUSION: The high blood pressure can be effectively controlled by carrying out the PC program such as medication consultation and health education etc in hypertensive patients.

OBJECTIVE: To discuss the focus of the legislative protective of Chinese traditional medicine. METHODS: The key elements in the legislative protective of Chinese traditional medicine were analyzed. RESULTS & CONCLUSION: Chinese traditional medicine literature, Chinese herbal medicine resources and medicinal genetic resources should be considered as the key elements in the legislative protective of Chinese traditional medicine.

OBJECTIVE: To discuss marketing combination program strategy of online drug store in China.METHODS: It was analyzed from aspects of product strategy,price strategy,channel strategy and promotion strategy.RESULTS & CONCLUSIONS: For product strategy of online drug store,great importance should be attached to the rational selection of products;the product strategy should manifest its advantage of low price;the distribution channel strategy should be conducive to the close rate and the promotion means in promoting strategy should be diversified.

OBJECTIVE: To bring forward feasible suggestions for Direct-to-Consumer(DTC) marketing of prescription drugs.METHODS: The importance of analysis of DTC marketing of prescription drugs in solving "unrealistically high" drug price because of asymmetric information and its role in sufferers' participating in self-health care were analyzed.The status quo and the problems faced in US DTC marketing were also analyzed.RESULTS & CONCLUSIONS: The marketing of prescription drugs can be extended to the sufferers in China,but we must pay attention to the checkup for DTC advertisement,the time of DTC advertisement being forbidden after the new drugs launched into the market and the scope for DTC marketing.

OBJECTIVE:To provide reference for the selection of marketing strategy for post-marketing drugs.METHODS:?2 test was employed to analyze the number of 4 marketing strategies(flank attack strategy,guerrilla strategy,defensive strategy and attack strategy)used for the 100 well-known drug brands(74 from domestic versus 26 from abroad),meanwhile the regular marketing strategies for the domestic vs.foreign drug enterprises and for the OTC drugs vs.prescribed drugs were analyzed.RESULTS & CONCLUSIONS:There were significant differences between domestic and foreign pharmaceutical enterprises in the use of guerrilla strategy and attack strategy,20 of the domestic brands(27.03%)vs.none of the foreign brands used guerrilla strategy(0.00%),however,the foreign enterprises prefer attack strategy than domestic enterprises(14 foreign brands(53.85%)vs.13 domestic ones(17.57%)).There were no significant differences between domestic and foreign brands in the application of flank attack strategy and defensive strategy,the same is true between OTC and prescription drugs in the four strategies mentioned above.

OBJECTIVE:To provide references for domestic pharmaceutical enterprises in making marketing-mix strategy. METHODS: ?2 test was performed to analyze the numbers of the product strategy,price strategy,place strategy and promotion strategy included in marketing-mix strategy of 100 well-known brand drugs (74 domestic brand drugs versus 26 foreign brand drugs),and the regular patterns for the application of the strategies were summarized. RESULTS & CONCLUSIONS: There is great difference between domestic brand drugs and foreign brand drugs in product strategy and price strategy. In terms of product strategy,the foreign drug enterprises attach more importance to concept marketing strategy than domestic counterparts do;as for price strategy,the domestic drug enterprises prefer low price-high promotion strategy while the foreign counterparts prefer high price-high promotion strategy. However,the difference between Chinese drug enterprises and foreign counterparts in channel strategy and promotion strategy is non-significant.

OBJECTIVE:To provide reference for the research and formulation of public health policies for children in the ru-ral area. METHODS:Questionnaire survey was designed to investigate the drug use of children in the township area of Fujian prov-ince using parents of children as subjects. RESULTS:Totally 986 questionnaires were sent out,and 969 were effectively received with effective rate of 98.28%.The education level of the respondents was low,that junior school education or below accounted for 54.49%;the respondents having trouble or difficulty in giving child drugs accounted for 97.85%;the frequency of choice for chil-dren who didn't cooperate with medication due to the taste or dosage was 17.91%;17.91% thought thatthere was not enough child-specific medication or varieties;17.71%didn't know the accurate dosage;when children suffer from common diseases,the majority of respondents would choose town clinics,accounting for 42.83%. Before giving the child drugs for the first time, 50.26% of respondents would read the instruction;16.49% of respondents couldn't understand the instruction;37.67% of respon-dentswould take the initiative to understand children's medication knowledge,22.19%wanted to know but did not have the channel,and 36.12%would read when had opportunity. 28.48%knew the difference of age and body mass in children's medi-cation,but 52.73%only had some understanding. 39.64% wanted to get the medication education from doctors,while 33.77%from pharmacist. Higher education held higher proportion on attention of children's medicine information,the extent of understand-ing children medication difference and the habit of reading drug instructions(P<0.001). CONCLUSIONS:Respondents in the town-ship have much trouble or difficulty in giving children drugs,children medication information is inadequate and inaccurate in pack-age inserts,there are many shortcomings in pharmaceutical care ability of township medical institutions,education and propaganda of rational drug use in children.

This study was aimed to investigate the relationship between the quality ofRheum palmatum L. and ecological factors, in order to provide the basis for nurture and cultivation ofR. palmatumL. The ultra performance liquid chromatography (UPLC) was used in the determination of 8 effective components in samples from 3 majorR. palmatumL. producing provinces, which wereGansu,SichuanandQinghai province. The SPSS software was applied to analyze the effective components by the one-way analysis of variance. And the correlation analysis between the content and ecological factors was also conducted. The results showed that the pressure, relative humidity and temperature had close relationship with the content of bioactive compounds inR. palmatumL. The content of effective components inR. palmatumL. was positively related to pressure, relative humidity, and temperature. It was concluded that the quality ofR. palmatumL. in Gansu province was better. And the ecological factors affected the accumulation of effective components. This research provided experimental basis for the quality ofR. palmatumL. in different regions and ecological adaptation. The results demonstrated critical meaning forR. palmatumL. quality improvement, appropriate ecological division, and industrialized development promotion ofR. palmatumL.

OBJECTIVE: To explore approaches for further development of pharmaceutical care in retail drugstores by strengthening drug administration. METHODS: The main problems occurred in pharmaceutical care were analyzed from the perspective of drug administration. RESULTS & CONCLUSIONS: The main problems occurred in pharmaceutical care were the absence of laws and regulations related to pharmaceutical care,misalignment between the access criteria for retail pharmacy and the necessary conditions for pharmaceutical care. The development of pharmaceutical care could be promoted by perfecting current law system,enhancing the access criteria for running retail drugstore,and strengthening drug administration etc.

Objective To evaluate the recovery of island ?-cell function through different terms of continuous subcutaneous insulin infusion(CSII)in diabetic patients with failure of oral hypoglycemic agents(OHA).Methods The 48 diabetic patients with OHA failure were divided into group A(10 cases,7-day CSII),group B(18 cases,14-day CSII)and group C(20 cases,28-day CSII).Results Compared with group A,the daily administration of basic dose and premeal supplementary dose of insulin at targeted glucose level were decreased in group B and C(P