2.Clinical effect evaluation of 131 I for treating elderly hyperthyroid heart disease
Wenjun ZHANG ; Lichun ZHENG ; Xiaoming ZHANG
Chongqing Medicine 2013;(25):2959-2960,2963
Objective To evaluate the clinical value of 131 I in the treatment of senile hyperthyroid heart disease .Methods 95 ca-ses of elderly hyperthyroid heart disease were orally treated by 131 I .The thyroid function was detected before 131 I therapy and in 3 months ,6 months and 1 year after treatment .The gated blood pool imaging was performed before treatment and in 1 year after treatment for evaluating the therapeutic effect .Results The cure rate was 97 .89% for hyperthyroidism ,100 .00% for paroxysmal atrial fibrillation and 84 .00% for persistent atrial fibrillation .FT3 ,FT4 and TSH levels had statistical difference between before treatment and in 3 ,6 ,12 months after treatment (P<0 .05) .The left ventricular systolic and diastolic function parameters had sta-tistical differences between before treatment and in 1 year after treatment (P< 0 .05) .The left ventricular systolic and diastolic function was improved significantly .Conclusion Selecting radioactive 131 I for treating elderly hyperthyroid heart disease is the key to improve hyperthyroid heart disease ,can effectively control the FT3 ,FT4 and TSH levels and improve the heart function .
3.Nosocomial Pulmonary Infection in Elderly Patients with Long-term Mechanical Ventilation
Xiaofen MOU ; Jinchuan ZHANG ; Wenjun XIA
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To investigate nosocomial pulmonary infection in elderly patients receiving long-term(at least 30 day) mechanical ventilation. METHODS Retrospective survey was carried out in the aged patients with long-term mechanical ventilation,who admitted from Jan 2002 to Jun 2005.The risk factors of common pneumonia were studied by means of Logistic regression analysis. RESULTS In 69 cases with long-term mechanical ventilation,53 patients were caught common pneumonia(76.81%).Pulmonary tuberculosis and plural tuberculosis were(7(10.14%)) and(1(1.14%)),respectively.Nontuberculous mycobacterial infection was identified in 3 cases(4.35%).There were 8 cases suffered from Pneumocystis carinii pneumonia(11.59%).The length of mechanical ventilation and aspiration seemed to be the important risk factors for the development of common bacterial pneumonia. CONCLUSIONS The most significant preventive measures of common pneumonia include short mechanical ventilation and prevention of aspiration of gastric contents.Mycobacterium tuberculosis,nontuberculous mycobacteria and P.carinii induced pneumonia also should be considered in the elderly with(long-term) mechanical ventilation.
4.Effect and nursing of red light irradiation corticosteroid dependent dermatitis
Yangfang WANG ; Wenjun ZHANG ; Xiaoying CHEN
Modern Clinical Nursing 2017;16(5):28-31
Objective To observe the effect of red light facial synthesis combined with comprehensive facial therapy on corticosteroid dependent dermatitis (hormone dependent dermatitis) and summarize the nursing strategies. Methods About 160 patients with hormone dependent dermatitis hospitalized in our hospital from June 2015 to March 2016, were equally divided into control group and study group:the control group was treated with conventional comprehensive therapy, while the study group with 30 min red light irradiation together with the nursing measures in the control group. The total symptom scores of the two groups were evaluated before treatment and 4 weeks after treatment. Results Before treatment, the total symptom scores of the control group were no significant difference between them (P>0.05). After treatment,the treatment effect of the study group was significantly better than that of the control group and the scores of ISS SSRI were lower than those of the control group . Conclusion The red light radiation combined with comprehensive facial therapy is effective in the treatment of corticosteroid dependent dermatitis and related nursing should be done well to promote patients relovery.
5.Effects of Calcium Ion on the Stability of Total Parenteral Nutrition Solution
Wenjun ZHANG ; Bin WANG ; Hejing CAO
China Pharmacy 2016;27(17):2339-2341,2342
OBJECTIVE:To study the effects of calcium ion(Ca2+)on the stability of total parenteral nutrition(TPN),and to provide reference for clinical use. METHODS:4 kinds of TPN containing different contents of Ca2+were prepared according to ster-ile operation procedure,and at room temperature,their microbial limit,appearance,pH value,osmotic pressure molar concentra-tion,the number of insoluble particle and emulsion particle size were investigated at 0,2,4,6,8 and 24 h. RESULTS:Within 24 h,no bacterial colony was found in TPN,and its appearance had no obvious change;pH value of TPN were all higher than 5 at different time points,without statistical significance(P>0.05);osmotic pressure molar concentration of TPN were all within the range of normal human blood(280-310 mOsmol/kg),without statistical significance(P>0.05). As the increase of Ca2+,the num-ber of insoluble particle ≥10 μm in TPN showed increasing tendency,with statistical significance (P<0.05);that ≥25 μm had no significant change,without statistical significance (P>0.05). There was statistical significance in emulsion partial size of TPN at different time points(P<0.05). CONCLUSIONS:Ca2+ can influence the stability of TPN,manifesting as the number of insolu-ble particle ≥10 μm and emulsion partial size increase. To garantee the safety of TPN use in the clinic,the concentration of biva-lent cation in TPN prescrption should be kept in reasonable range,and TPN should be used as soon as possible after preparation.
6.Variable Selection by Orthogonal Descriptors and Prediction of Rf Value of Phenol and Aniline Derivatives
Wenjun ZHANG ; Lu XU ; Yuhua QI
Chinese Journal of Analytical Chemistry 2001;29(2):178-181
Orthogonal descriptors is a viable method for variable selection, but this method strongly depend on the orthogonalisation ordering of the descriptors. In this paper, we compared the different methods used for order the descriptors. It showed that better results could be achieved with the use of backward elimination ordering. We predieted Rf value of phenol and aniline derivatives by this method, and compared it with classical algorithms such as forward selection, backward elimination, and stepwise procedure. Some interesting hints were obtained.
7.Treatment of SIRT for unresectable hepatic metastasis from colorectal cancer
Fangjuan HU ; Wenjun ZHANG ; Changlin ZHAO
Journal of International Oncology 2011;38(9):703-707
Colorectal cancer is the third high incidence of tumor in the world,and liver is one of the most common sites of distant metastasis.Liver metastasis accounts for 50%-75% in distant metastasis.Only about 10% -15% of patients are candidates for resection,and the recurrence is easy.Selective internal radiation therapy is a new type of radiotherapy.It is partial and liver-targeted.For unresectable colorectal liver metastasis,selective internal radiation therapy alone or in combination with other therapies can reduce cancer focus,prolong the survival,and maybe improve overall survival.
8.Investigation in climacteric symptoms and depression of gynaecology outpatients and inpatients
Yuanyuan ZHANG ; Caifeng ZHOU ; Wenjun FU
Chinese Journal of Practical Nursing 2011;(31):62-64
Objective To investigate the climacteric symptoms and depressive related factors of climacteric females in gynecology outpatients and inpatients,to provide evidence for effective health promotion.Methods 416 climacteric women were investigated by using improved menopause Kuppermen Scales and Center for Epidemiological Studies Depression (CES-D).The results underwent analysis.Results There were 93.99% of patients suffering from climacteric syndrome,49.52% with depression symptom.The main factors of climacteric syndrome were eating breakfast according to the timetable every day,nutritionally balanced diet,controlling of salt intake,regular body exercises and to maintain a proper body weight.Factors related to depression symptoms were sore breasts,constipation,dry skin,lower abdominal pain.The correlation between climacteric syndrome and depressive symptom was significant.Conclusions The main influencing factor of climacteric syndrome was healthy lifestyle.The climacteric syndrome increases the risk of depressive symptoms.
9.Detection of myocardial coronary flow reserve of syndrome X by real-time myocardial contrast echocardiography
Wenjun ZHANG ; Shaowen GUO ; Yi HE
Chinese Journal of Ultrasonography 2009;18(4):308-310
Objective To evaluate myocardial coronary flow reserve of syndrom X by real-time myocardial contrast echocardiography(MCE). Methods Ten patients with syndrome X and seven normal subjects were involved in the study. Real-time MCE was performed with acoustic contrast SonoVue,and the peak video density (A), and re-turgor velocity of microvessel (β), and the product of A ×β of quiescent condition and after adenosin loading were detected,and also the coronary flow reserve (CFR, the ratio of A xβ circa-adenosin loading). Results There was no significant difference of A between syndrom X and contrast group in quiescent condition, the β and product of A x β of patients with syndrome X were lower than those of contrast group, the CFR of syndrome X was obviously less than that of contrast group.Conclusions Myocardial microvessel function is abnormal in syndrome X, real-time MCE is useful for evaluate myocardial coronary flow reserve.
10.Cause analysis of intracranial hemorrhage during operation on patients with brain injury
Xuejun ZHANG ; Wei LIANG ; Wenjun CHEN
Chinese Journal of Primary Medicine and Pharmacy 2010;17(9):1173-1174
Objective To study the possible reasons and the processing strategy of brain injury operation complicated with intracranial hemorrhage.Methods The clinical data about 22 patients who were digged skull operation because of brain injury and complicated with intracranial hemorrhage in operation in neurosurgery from 2007 June to 2008 February were retrospectively analyzed,and different types intracranial hemorrhage were classified.Results In 22 patients,12 patients were complicated with epidural hematoma,in which the patients (9/12,75.0%) complicated with opposite hematoma were common;5 patients were complicated with intracerebral hematoma,in which the patients (3/5,60%) complicated with ipsilateral hematoma were common;4 patients were complicated with acute subdural hematoma,and all the patients complicated with opposite hematoma;1 patient was complicated with sub-flap hematoma.Conclusions In the patients who are complicated with intracranial hemorrhage because of digging skull operation to brain injury,epidural hematoma are most,then intracerebral hematoma,subdural hematoma,sub-flap hematoma.The important measures of preventing secondary intracranial hemorrhage are definiting force mechanism and distinguishing fracture line before operation,gradiently decompressing,completely removing crushing brain tissue,protecting reflux veins,rigorously stopping bleeding during operation.