1.A design of hanger-unnecessary infusion bottle and its tube for pre-hospital rescue
Journal of Medical Postgraduates 2003;0(06):-
Objective:To design a hanger-unnecessary infusion bottle and its tube. Methods:According to internal pressuring mechanism, the defects of height and direction-necessity of the present infusion bottles and tubes had been successfully overcome. Results:Fluid infusion can now be applied at any height, in any direction and position without any danger of air-entering into blood vessels. It is useful for pre-hospital rescue, battle-field, patient-transferring or urgent and large number of fluid/blood infusion.Conclusion:The design can be used both in hospitals as a present-used normal infusion bottles or bags and for pre-hospital hanger-unnecessary use. It can replace the present-used infusion bottles and their tubes.
2.An Ethical Reflection on Psychological Health Management of College Students
Chinese Medical Ethics 1995;0(04):-
This article analyzes a series of ethical issues in the psychological health management of college students,puts forward some corresponding ethical countermeasures from the perspectives of reasonable objectives,principles,contents and operational process of the psychological health management on the basis of people-oriented and harmonious concept in order to correctly deal with ethical issues of psychological health management,and promote the development of psychological health management.
3.Total cost of hospitalization after internal fixation of intertrochanteric fracture
Chinese Journal of Orthopaedic Trauma 2016;18(2):138-143
Objective To analyze the factors influencing the total cost of hospitalization after internal fixation of intertrochanteric fracture.Methods Enrolled in this study were 142 patients with intertrochanteric fracture who had been treated at our department between March 2013 and August 2014.They were 54 men and 88 women,aged from 24 to 95 years (average 69.8 years).Intramedullary fixation was adopted in 135 cases while extramedullary fixation in 7.By AO classification,32 cases were type A 1,75 type A2 and 35 type A3.We analyzed their demographic data,fracture-associated factors,bleeding-associated factors and surgery-associated factors.For univariate analysis,the independent sample t test was performed between 2 groups.One-Way ANOVA analysis was performed among several groups.For multivariate analysis,multivariate linear regression analysis was performed.P < 0.05 was regarded as statistically significant.Results The independent sample test revealed that the total cost of hospitalization for those with preoperative deep venous thrombosis (6.9 ± 1.0 × 105 (¥)) was significantly higher than for those without (5.0 ± 0.8 × 105 (¥)) and the total cost for those undergoing intramedullary fixation (5.5 ± 1.2 × 105 (¥)) was significantly higher than for those undergoing extramedullary fixation (4.4 ±0.7 × 105 (¥)) (P < 0.05).The multiple linear regression analyses showed that preoperative deep venous thrombosis (t =11.750,P < 0.001),perioperative transfusion (t =2.803,P =0.006),hospital stay (t =5.949,P < 0.001) and intraoperative blood loss (t =2.885,P =0.005) were the independent factors influencing the total cost of hospitalization.Conclusions Preoperative deep venous thrombosis,perioperative transfusion,intraoperative blood loss,and hospital stay may influence the total cost of hospitalization for patients undergoing internal fixation of intertrochanteric fracture.More attention should be paid to control of the total cost of hospitalization in addition to ensuring the perioperative life safety.
4.Effects of exercise on behavior and serum cortisol in depression due to chronic mild stress
Songbin HE ; Xiaotong WANG ; Wenjie TANG
Chinese Journal of Physical Medicine and Rehabilitation 2008;30(5):289-292
Objective To investigate the effects of exercise on behavior and serum cortisol levels in depression caused by chronic,unpredictable,mild stress(CUMS).Methods Forty-eight male Sprague-Dawley rats were randomly divided into 3 groups:A,B and C.Each group was then divided into 3 subgroups:a blank control subgroup,a model subgroup,and an intervention subgroup.CUMS such as unpredictable forced swimming in cold water,electric stimulation of the animals'feet and shaking of the cage was used to establish a model of depression.Swimming exercise was administered as a therapeutic intervention.In group A it was administered while the animals were under stress,while in groups B and C,exercise was administered before and after the depression model had been established.Open-field test and fluid consumption data were recorded during the whole procedure.At the end of the experiment,radioimmunity assays were used to measure the levels of serum cortisol.Results Rats exposed to CUMS showed reduced water consumption;a preference for sucrose solutions;and decreased squares crossed,less rearing and increased bowel movement in open-field test.All of these changes were mitigated by the exercise performed while the animals were under stress,but not by exercise before or after the depression model had been established.Rats exposed to CUMS showed significant increases in serum cortisol,which was mitigated by exercise prior to and during stress.Conclusion Different exercise routines have different effects on behavior and serum cortisol levels in depressive rats under chronic unpredictable mild stress.Exercise has cumulative effects in decreasing the serum level of cortisol,but has only immediate effects on the behavior of depressive rats.
5.Application of active targeting liposome for tumor MRI
Wenjie TANG ; Ruimeng YANG ; Xinqing JIANG
Chinese Journal of Nuclear Medicine and Molecular Imaging 2014;34(6):518-520
As a carrier for MRI contrast agent,active targeting liposome demonstrates distinct advantages in tumor diagnosis and treatment due to its characteristics of biocompatibility,non-toxicity and targeting ability.Tumor targeting imaging with liposome labeled with molecular recognition system,or liposome sensitive to pH value or temperature is a popular research topic.The application of various types of active targeting liposome for tumor magnetic resonance imaging is reviewed in this review.
6.Antiendothelial cell antibodies in systemic vasculitis:prevalence and clinical significance
Wenjie ZHENG ; Yan ZHAO ; Fulin TANG
Chinese Journal of Rheumatology 2003;0(11):-
Objective To investigate the clinical significance of antiendothelial cell antibodies (AECA) in systemic vasculitis. Method With Human umbilical vein endothelial cell (HUVEC) as substrate cell, sera from 129 systemic vasculitis patients [including 59 Behcet′s disease(BD), 28 Takayasu arteritis (TA), 20 Wegener′s granulomatosis (WG), 8 polyarteritis nodosa (PAN), 9 microscopic polyangiitis (MPA), 5 Churg-Strauss syndrome (CSS)] were screened for the presence of AECA by ELISA. Sera from SLE, RA and healthy donors were examined as controls. The association of AECA to clinical disease activity was analyzed. Result The prevalence of AECA by HUVEC cell-ELISA was 59% in systemic vasculitis [48% in BD,79% in TA, 65% in WG, 63% in PAN, 44% in MPA, 80% in CSS], 46% in SLE, 4% in RA, and 2.4% in control group. Compared with patients with RA and control group, AECA were more frequently found in patients with systemic vasculitis and SLE (P
7.Effect and Action Mechanism of Group Tutoring in Adaptation Education for College Freshmen
Qingjian CHEN ; Sijia MEI ; Wenjie TANG
Chinese Medical Ethics 1995;0(03):-
Objective:To explore the effect of group tutoring in the adaptation education for college freshmen.Method:All freshmen that attended Wenzhou medical college in 2008 are enrolled in group tutoring to help them better adapt to the new life in college,and the tutoring effect is appraised by a self-designed questionnaire.Result:The freshmen show a general progress and satisfaction after receiving group tutoring,and regard it quite necessary to conduct activities like group tutoring at the beginning of college life to help make freshmen better adaptive.Conclusion:Group tutoring is very effective in the adaptation education for college freshmen,and has a universal applicability for all college students.
8.Research on the Mechanism of Social Responsibility Improvement among Medical Students in the Perspective of Medical Charity
Chunyan ZENG ; Wenjie TANG ; Chanjuan LIU
Chinese Medical Ethics 2016;29(2):340-343
Objective:To meet the multitier needs of medical students′ health and health career development through the establishment of relevant mechanisms for medical charity and strengthening the social responsibility theme education among medical students. Methods:The present study was conducted in a stratified sample using the method of investigation mainly. The questionnaire was self -conducted; in the end 967 valid questionnaires were collected and combined with 48 relevant interviews. The data was analyzed using SPSS l6. 0. Results: The current positive trends of social responsibility among medical students are gratifying. The students had correct atti-tude to study but the initiative needed to be improved. The professional cognition was optimistic but the morality emphasis needed to be strengthened. The capacity cognitive was clearly but the awareness of accountability needs to be improved. The social consciousness was intense but responsibility needed to be strengthened. The life value was positive but the physical and mental health needed concerns. And it was needed to further strengthen social respon-sibility education. Conclusion: We should make full use of the excellent resources of the Affiliated Hospital of Medical College. With the medical charity starting point, the social responsibility should be strengthened through the Five in One promotion mechanism that including the culture education leading, clinical practice inspiring, social practice annealing, campus culture edifying, and powers of role model effecting.
9.Muscle strength test of acetabular fracture patients following Kocher-Langenbeck posterior approach surgery:Peri-hip power analysis in 36 cases
Wenjie TANG ; Manyi WANG ; Shiwen ZHU
Chinese Journal of Tissue Engineering Research 2007;0(44):-
Thirty-six patients with acetabular fracture undergoing Kocher-Langenbeck approach surgery in Beijing Jishuitan Hospital between January 2001 and December 2005 were selected.All patients underwent tibial tubercle or femoral upper condyle traction before surgery.People with traumatic arthritis or other lower limb injury on postoperative X-ray were excluded.Using Biodex system to test the abduction and extension muscle at 60( ?)/s and 180( ?)/s.Peak torque,total work,and mean power were used for evaluation.The difference between bilateral limbs ≤ 10% was normal,≥ 20% was abnormal and 11%-19% was suspected.The muscle strength in fast test was more than the slow test(t=2.21,P
10.Application of the problem-based learning teaching method in clinical teaching of orthopedics
Wenjie GUO ; Donghua SHAO ; Xiaosui TANG
Chinese Journal of Medical Education Research 2015;14(10):1036-1040
Objective To evaluate the application effect of the problem based learning in clinical teaching of orthopedics. Methods We chose sixty five-year program students of Peking univ-ersity health science center as research object. All students were randomly divided into experimental and control groups, with thirty students in each group. Experimental group was given PBL teaching combined with lecture based learning (section-based learning, LBL), while the control group only received the LBL teaching. Two groups were given 8 hours of teaching experiments. After the end of the study, the teaching effect of the two groups was evaluated by the theory course and clinical skills. The questionnaire was distributed to the 2 groups. The scores of both experimental group students and control group students in theory courses and clinical skills were analyzed using SPSS 19.0 software using t-test and x2 test. Result The score of the experimental group was (53.7 ±3.2) in the knowl-edge-based grades exam, while the control group was (52.3±2.2), showing no obvious difference when compared to the control group's grades (P>0.05). The score of the experimental group was (24.0±1.5) in the hands-on technique grades exam, while the control group was (22.3±1.6). The difference in grades showed statistical significance (P<0.05). Feedback survey results showed that the experimental group's teaching satisfaction degree was also significantly higher than the control group, and the dif-ference was statistically significant (P<0.05). Conclusions The application of PBL in clinical teach-ing in orthopedic clinical teaching can improve students' learning interest and self-study ability, and helps to develop students' clinical thinking ability. But the role of PBL teaching in improving students' medical knowledge level is not obvious.