The paper analyzes the potential safety hazards of infusion work of the hospital,introduces the hardware environment,business process and topological structure of the mobile infusion system,puts forward the solution to the mobile infusion system based on intelligent terminal PDA,Wireless Local Area Network (WLAN) and barcode recognition,and optimizes the system according to the utilization condition,in order to improve the operating efficiency in the meantime of eliminating the potential safety hazards of infusion.

The paper introduces the implementation of wireless mobile ward -round from network deployment and equipment deploy-ment, explains critical techniques during the implementation process , analyzes the application effect of wireless mobile ward -round from the perspective of doctors , patients and data security , and points out that the wireless mobile ward -round has broad application prospect in clinical practice .

Since the first successful establishment of human embryonic stem cell line in 1998,embryonic stem cell research has attracted much attention in recent years.Theoretically,embryonic stem cells are pluripotent 0f in vitro proliferation and in vivo differentiation.which could serve as a promising seed cell source for cell thera PY or tissue engineering.Differentiation of the embryonic stem cells into a certain type of cell still remains a big challenge.Studies regarding chondrogenic ifferentiation have been reported.This article summarizes the chon drogenic process in developing embryo and the currently known factors involved in the in vitro chondrogenic differentiation of embryonic stem cell.Foreground of the study in this field is discussed.

Adult ; Aged ; Carcinoma, Squamous Cell ; diagnostic imaging ; pathology ; therapy ; Chemotherapy, Adjuvant ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Radiotherapy, Adjuvant ; Survival Rate ; Thymus Neoplasms ; diagnostic imaging ; pathology ; therapy ; Tomography, X-Ray Computed

Objectives:In the study, effect of Ala Gln on glutathione concentration and antioxidation were investigated in burned rats . Methods:Thirty male SD rats were randomly divided into three groups,A:control group,B:TPN group,C:Ala Gln PN group.The nutrient solution was administered through central venous catheter for 7 days.Glutathione concentration and levels of xanthine oxidase(XOD) and superoxide dismutase(SOD) in the serum were determined. Results:Compared with control group and TPN group,the levels of serum glutathione and SOD in group C were significantly increased( P

OBJECTIVE: To explore the effects of allergic factores in eosinophilic nasal polyps. METHOD: Clinical characters of 67 eosinophilic nasal polyps patients and 26 lymphocyte nasal polyps patients were restrospeetively analyzed. Allergic factors, allergens and nasal anatomic variations were compared between two groups. RESULT: Allergic factors are proned to present in eosinophilic nasal polyps group compared with lymphocyte nasal polyps group; The positive rates of allergen skin test between eosinophilic nasal polyps group and lymphocyte nasal polyps group showed significant difference; Allergens in eosinophilic nasal polyps group are different from lymphocyte nasal polyps group; Nasal anatomic variations are different between two groups. CONCLUSION Different pathogenesis maybe exist in different pathological type nasal polyps. Allergic factors are closely relative to eosinophilic nasal polyps and nasal anatomic variations play a more important role in the formation of lymhocyte nasal polyps.
Allergens ; immunology ; Eosinophils ; pathology ; Humans ; Hypersensitivity ; immunology ; Nasal Polyps ; immunology ; physiopathology ; Nose ; anatomy & histology ; Skin Tests

OBJECTIVE: To investigate the distribution of mast cells in nasal polyps. METHOD: Biopsy specimens from patients with nasal polyps (n = 20) and control patients (n = 8) were obtained and included in this study. The distribution of mast cells in nasal polyps and the expression of chemokines (CCL5, CCL11, CX3CL1, IL-8, IL-6) in the epithelial cells of normal nasal mucosa and nasal polyps was determined by immunohistochemistry. RESULT: Mast cells migrate to intraepithelial in nasal polyps and the expression of chemokines (CCL5, CCL11, CX3CL1, IL-8) was up regulated in the epithelial cells of nasal polyps compare to normal nasal mucosa. CONCLUSION Our findings showed that mast cells migrate to intraepithelial in nasal polyps and the over expression of chemotaxins (CCL5, CCL11, CX3CL1, IL-8) may be response for mast cells' migration in nasal polyps. Mast cells might be associated with the development of nasal polyps.
Chemokine CCL11 ; metabolism ; Chemokine CCL5 ; metabolism ; Chemokine CX3CL1 ; metabolism ; Epithelial Cells ; metabolism ; Humans ; Immunohistochemistry ; Interleukin-6 ; metabolism ; Interleukin-8 ; metabolism ; Mast Cells ; metabolism ; pathology ; Nasal Mucosa ; cytology ; metabolism ; Nasal Polyps ; metabolism ; pathology ; Up-Regulation

Objective To compare the effectiveness,safety and related clinical indicators between simple drainage treatment and drainage treatment combined with intrathoracic urokinase for children with parapneumonic pleural effusion(PPE).Methods Twenty-nine in patients with PPE given pleural effusion drainage in the First Affiliated Hospital of Zhengzhou University from January 2013 to December 2015 were selected as research subjects,who were divided into a simple group and an urokinase group based on whether intrathoracic urokinase was injected or not.The total number of hospital stay,the total drainage volume,the total number of catheter days,the total cost,the days with fever,efficient rate,operation rate and security of the patients were retrospectively analyzed between two groups.Results The intrathoracic days of hospital stay [M(P25,P75)] of urokinase group[19(11,30) days]were less than those of simple group[30(21,38) days],and the difference was significant (Z =-2.545,P =0.011);the total drainage volume[M(P25,P75)] of the urokinase group [430 (175,1 308) mL] was more than that of the simple group [110 (10,325)mL],and the difference was significant (Z =-2.811,P =0.005);the total number of catheter days [M (P25,P75)] of urokinase group [9 (7,19) days] was less than that of the simple group [20 (10,30) days],and the difference was significant (Z =-2.020,P =0.043);the total cost [M(P25,P75)] of the urokinase group [20 000(10 000,30 000)RMB] was less than that of the simple group [40 000 (30 000,50 000) RMB],and the difference was significant (Z =-2.631,P =0.009);the days with fever between urokinase group and the simple group was not significant (Z =-0.820,P =0.412).The urokinase group had a higher cure rate[76.9％ (10/13 cases)] and a lower surgical rate [23.1％ (3/13 cases)] compared with those of the simple group[18.7％ (3/16 cases),81.3％ (3/16 cases)],and the difference was significant (x2 =9.814,P =0.003).Conclusions Intrapleural urokinase therapy as an adjuvant treatment of PPE is simple and convenient,economic,higher efficiency,lower risk,which can be used as an effective clinical solution such disease.

Objective To evaluate the efficacy and safety of intrapleural fibrinolytic agents in the treatment of childhood empyema.Methods The data from China National Knowledge Infrastructure (CNKI),Chinese BioMedical (CBM),PubMed,VIP Database and Cochrane library were reviewed.Randomized control trials by using intrapleural fibrinolytic agents to treat childhood empyema were included.Two reviewers independently extracted the data from the eligible studies and evaluated the quality of the included studies.Meta-analysis was performed for the results of homogeneous studies using RevMan 5.2 software,while others analyzed descriptively.Results Five randomized control trials involving 248 children with empyema were included.Meta-analysis was not made in all of the indexes because of apparent heterogeneity and limited data.Two trials were compared which involved 98 patients receiving fibrinolytic agents or 9 g/L saline.The results suggested that fibrinolytic agents shortened the length of hospital stay and reduced complication(all P ＜ 0.05),but no significant differences were found between the 2 groups in the effective rate,duration of fever and pleural effusion amount(OR =3.61,95％ CI 0.84-15.49,P ＞ 0.05).Three trials involving 150 patients compared fibrinolytic agents and video-assisted thoracoscopic surgery (VATS).The data suggested that no significant differences were found between 2 groups in the effective rate (OR =0.70,95 ％ CI 0.30-0.61,P ＞ 0.05),but fibrinolytic agents cost less (P ＜ 0.05).The adverse drug reactions to intrapleural fibrinolytic agents were mild to moderate,and well tolerated.Conclusions The findings suggest that intrapleural fibrinolytic agents in the treatment of childhood empyema is safe and effective,especially in encapsulated effusion.Compared to 9 g/L saline,it can shorten the length of hospital stay and reduce complication.Compared with VATS,the curative effect is similar,while intrapleural fibrinolytic agents are economic.

Objective To investigate the change of the serum content of adiponectin in the elderly, and the relationship between hepatic steatosis and the serum content of adiponectin and metabolic syndrome.Methods 264 elderlies were divided into the hepatic steatosis group (87 cases) and control group (177 cases) after B type ultrasonograph examination. The height, weight, waist circumference and levels of serum lipid, glucose, insulin and adiponectin of all cases in the two groups were measured. The relationship between above variables and hepatic steatosis was analyzed. The multiple logistic regression analysis was used to test the efficacy of adiponectin and metabolic syndrome for predicting the probability of having hepatic steatosis in the elderly.Results For the hepatic steatosis group, the serum content of adiponectin was significantly lower than that of the control group ( P<0.01), the frequency of metabolic syndrome was significantly higher than that of the control group ( P<0.01), and the body mass index, waist circumference, blood glucose (fasting blood glucose and postprandial blood glucose), homeostasis model assessment-insulin resistance index, total cholesterol, triglyceride and low density lipoprotein cholesterol increased and high density lipoprotein cholesterol decreased. Logistic regression analysis showed that serum content of adiponectin and metabolic syndrome were associated with the probability of hepatic steatosis.Conclusion The serum content of adiponectin and metabolic syndrome are useful indices for the prediction of hepatic steatosis.