1.Implementation of Wireless Mobile Ward-round in Hospitals
Journal of Medical Informatics 2015;(10):38-40
The paper introduces the implementation of wireless mobile ward -round from network deployment and equipment deploy-ment, explains critical techniques during the implementation process , analyzes the application effect of wireless mobile ward -round from the perspective of doctors , patients and data security , and points out that the wireless mobile ward -round has broad application prospect in clinical practice .
2.The Solution to the Mobile Infusion System of the Hospital
Journal of Medical Informatics 2017;38(7):26-29
The paper analyzes the potential safety hazards of infusion work of the hospital,introduces the hardware environment,business process and topological structure of the mobile infusion system,puts forward the solution to the mobile infusion system based on intelligent terminal PDA,Wireless Local Area Network (WLAN) and barcode recognition,and optimizes the system according to the utilization condition,in order to improve the operating efficiency in the meantime of eliminating the potential safety hazards of infusion.
3.Research progress in chondrogenic differentiation of embryonic stem cells
International Journal of Biomedical Engineering 2008;31(3):150-154
Since the first successful establishment of human embryonic stem cell line in 1998,embryonic stem cell research has attracted much attention in recent years.Theoretically,embryonic stem cells are pluripotent 0f in vitro proliferation and in vivo differentiation.which could serve as a promising seed cell source for cell thera PY or tissue engineering.Differentiation of the embryonic stem cells into a certain type of cell still remains a big challenge.Studies regarding chondrogenic ifferentiation have been reported.This article summarizes the chon drogenic process in developing embryo and the currently known factors involved in the in vitro chondrogenic differentiation of embryonic stem cell.Foreground of the study in this field is discussed.
5.Modified Reconstruction of Old Rupture of Finger Flexor Tendon
Wenjie ZHUANG ; Xuefeng TANG ; Qianli LONG ; Zhongkui YANG ; Shi CHEN
Chinese Journal of Rehabilitation Theory and Practice 2013;19(10):981-983
Objective To explore the effect of reconstruction on old rupture of finger flexor tendon. Methods There were 30 patients (54 fingers) with old rupture of finger flexor tendon. The silica gel stick was implanted at the first stage. The palmaris longus tendon wrapped in the bioabsorbable membrane replaced the silica gel stick and was implanted at the second stage. The effectiveness was assessed by total active movement (TAM). Results There were 30 fingers as excellent, 20 fingers as good among 54 fingers of 30 patients. The percent of excellent and good was 92.6%. Conclusion Modified reconstruction is effective to prevent from tendon adhesion.
6.Comparison of simple drainage or drainage combined with urokinase for parapneumonic pleural effusion in children
Jianjiang ZHANG ; Yinghua CHEN ; Wenjie DOU ; Peipei SHI ; Huiqin ZENG
Chinese Journal of Applied Clinical Pediatrics 2016;31(17):1329-1331
Objective To compare the effectiveness,safety and related clinical indicators between simple drainage treatment and drainage treatment combined with intrathoracic urokinase for children with parapneumonic pleural effusion(PPE).Methods Twenty-nine in patients with PPE given pleural effusion drainage in the First Affiliated Hospital of Zhengzhou University from January 2013 to December 2015 were selected as research subjects,who were divided into a simple group and an urokinase group based on whether intrathoracic urokinase was injected or not.The total number of hospital stay,the total drainage volume,the total number of catheter days,the total cost,the days with fever,efficient rate,operation rate and security of the patients were retrospectively analyzed between two groups.Results The intrathoracic days of hospital stay [M(P25,P75)] of urokinase group[19(11,30) days]were less than those of simple group[30(21,38) days],and the difference was significant (Z =-2.545,P =0.011);the total drainage volume[M(P25,P75)] of the urokinase group [430 (175,1 308) mL] was more than that of the simple group [110 (10,325)mL],and the difference was significant (Z =-2.811,P =0.005);the total number of catheter days [M (P25,P75)] of urokinase group [9 (7,19) days] was less than that of the simple group [20 (10,30) days],and the difference was significant (Z =-2.020,P =0.043);the total cost [M(P25,P75)] of the urokinase group [20 000(10 000,30 000)RMB] was less than that of the simple group [40 000 (30 000,50 000) RMB],and the difference was significant (Z =-2.631,P =0.009);the days with fever between urokinase group and the simple group was not significant (Z =-0.820,P =0.412).The urokinase group had a higher cure rate[76.9% (10/13 cases)] and a lower surgical rate [23.1% (3/13 cases)] compared with those of the simple group[18.7% (3/16 cases),81.3% (3/16 cases)],and the difference was significant (x2 =9.814,P =0.003).Conclusions Intrapleural urokinase therapy as an adjuvant treatment of PPE is simple and convenient,economic,higher efficiency,lower risk,which can be used as an effective clinical solution such disease.
7.Systematic review of intrapleural fibrinolytic agents in treatment of childhood empyema
Wenjie DOU ; Jianjiang ZHANG ; Peipei SHI ; Na WANG ; Huiqin ZENG
Chinese Journal of Applied Clinical Pediatrics 2015;30(7):541-544
Objective To evaluate the efficacy and safety of intrapleural fibrinolytic agents in the treatment of childhood empyema.Methods The data from China National Knowledge Infrastructure (CNKI),Chinese BioMedical (CBM),PubMed,VIP Database and Cochrane library were reviewed.Randomized control trials by using intrapleural fibrinolytic agents to treat childhood empyema were included.Two reviewers independently extracted the data from the eligible studies and evaluated the quality of the included studies.Meta-analysis was performed for the results of homogeneous studies using RevMan 5.2 software,while others analyzed descriptively.Results Five randomized control trials involving 248 children with empyema were included.Meta-analysis was not made in all of the indexes because of apparent heterogeneity and limited data.Two trials were compared which involved 98 patients receiving fibrinolytic agents or 9 g/L saline.The results suggested that fibrinolytic agents shortened the length of hospital stay and reduced complication(all P < 0.05),but no significant differences were found between the 2 groups in the effective rate,duration of fever and pleural effusion amount(OR =3.61,95% CI 0.84-15.49,P > 0.05).Three trials involving 150 patients compared fibrinolytic agents and video-assisted thoracoscopic surgery (VATS).The data suggested that no significant differences were found between 2 groups in the effective rate (OR =0.70,95 % CI 0.30-0.61,P > 0.05),but fibrinolytic agents cost less (P < 0.05).The adverse drug reactions to intrapleural fibrinolytic agents were mild to moderate,and well tolerated.Conclusions The findings suggest that intrapleural fibrinolytic agents in the treatment of childhood empyema is safe and effective,especially in encapsulated effusion.Compared to 9 g/L saline,it can shorten the length of hospital stay and reduce complication.Compared with VATS,the curative effect is similar,while intrapleural fibrinolytic agents are economic.
8.Relationship between allergic factors and eosinophilic nasal polyps.
Guimin ZHANG ; Jinmei ZHANG ; Wenjie SHI ; Peiyong SUN ; Peng LIN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(12):1098-1100
OBJECTIVE:
To explore the effects of allergic factores in eosinophilic nasal polyps.
METHOD:
Clinical characters of 67 eosinophilic nasal polyps patients and 26 lymphocyte nasal polyps patients were restrospeetively analyzed. Allergic factors, allergens and nasal anatomic variations were compared between two groups.
RESULT:
Allergic factors are proned to present in eosinophilic nasal polyps group compared with lymphocyte nasal polyps group; The positive rates of allergen skin test between eosinophilic nasal polyps group and lymphocyte nasal polyps group showed significant difference; Allergens in eosinophilic nasal polyps group are different from lymphocyte nasal polyps group; Nasal anatomic variations are different between two groups.
CONCLUSION
Different pathogenesis maybe exist in different pathological type nasal polyps. Allergic factors are closely relative to eosinophilic nasal polyps and nasal anatomic variations play a more important role in the formation of lymhocyte nasal polyps.
Allergens
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immunology
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Eosinophils
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pathology
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Humans
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Hypersensitivity
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immunology
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Nasal Polyps
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immunology
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physiopathology
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Nose
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anatomy & histology
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Skin Tests
9.Distribution change of mast cells in human nasal polyps.
Guimin ZHANG ; Wenjie SHI ; Peiyong SUN ; Peng LIN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(17):1337-1340
OBJECTIVE:
To investigate the distribution of mast cells in nasal polyps.
METHOD:
Biopsy specimens from patients with nasal polyps (n = 20) and control patients (n = 8) were obtained and included in this study. The distribution of mast cells in nasal polyps and the expression of chemokines (CCL5, CCL11, CX3CL1, IL-8, IL-6) in the epithelial cells of normal nasal mucosa and nasal polyps was determined by immunohistochemistry.
RESULT:
Mast cells migrate to intraepithelial in nasal polyps and the expression of chemokines (CCL5, CCL11, CX3CL1, IL-8) was up regulated in the epithelial cells of nasal polyps compare to normal nasal mucosa.
CONCLUSION
Our findings showed that mast cells migrate to intraepithelial in nasal polyps and the over expression of chemotaxins (CCL5, CCL11, CX3CL1, IL-8) may be response for mast cells' migration in nasal polyps. Mast cells might be associated with the development of nasal polyps.
Chemokine CCL11
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metabolism
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Chemokine CCL5
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metabolism
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Chemokine CX3CL1
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metabolism
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Epithelial Cells
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metabolism
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Humans
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Immunohistochemistry
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Interleukin-6
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metabolism
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Interleukin-8
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metabolism
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Mast Cells
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metabolism
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pathology
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Nasal Mucosa
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cytology
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metabolism
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Nasal Polyps
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metabolism
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pathology
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Up-Regulation
10.Effect of alanyl-glutamine dipeptide on glutathione concentration and antioxidation in burned rats
Yingqin SHI ; Wenjie ZHANG ; Qing WANG ; Xiaopeng ZHANG ; Jianli ZHOU ;
Parenteral & Enteral Nutrition 1997;0(01):-
Objectives:In the study, effect of Ala Gln on glutathione concentration and antioxidation were investigated in burned rats . Methods:Thirty male SD rats were randomly divided into three groups,A:control group,B:TPN group,C:Ala Gln PN group.The nutrient solution was administered through central venous catheter for 7 days.Glutathione concentration and levels of xanthine oxidase(XOD) and superoxide dismutase(SOD) in the serum were determined. Results:Compared with control group and TPN group,the levels of serum glutathione and SOD in group C were significantly increased( P