1.Research on human eye cornea's mathematical model and application in diopter correction.
Jianxin SHEN ; Yunhai ZHANG ; Ligang HU ; Wenhe LIAO
Journal of Biomedical Engineering 2003;20(4):695-699
The excimer laser diopter correction has proven to be efficient and safe. This paper presents the principle of excimer laser refractive surgery. Based on analyzing the mathematics model of the human eye cornea, the authors have proposed a new model which can be used to proceed the myopia, hyperopia, astigmatism diopter correction. Also studied were the excimer laser's ablation mechanism and the flying-spot scanning technology. The research results have been directly applied to Ophthalmic excimer laser system. The correction of diopter is well improved.
Algorithms
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Cornea
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anatomy & histology
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Humans
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Keratomileusis, Laser In Situ
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methods
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Lasers, Excimer
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Models, Theoretical
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Photorefractive Keratectomy
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methods
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Refractive Surgical Procedures
2.The mechanism and application of the correction for spherical myopia using small beam excimer laser.
Yunhai ZHANG ; Jianxin SHEN ; Wenhe LIAO ; Bin SUN
Journal of Biomedical Engineering 2005;22(2):355-359
In the laser ablation refractive surgeries, the corneal ablation model and its realization by laser are difficult to design. They greatly affect the results of those surgeries. This paper firstly presents a mathematical model for corneal ablation to correct the refractive error of spherical myopia, and then gives a technique of planning laser focus positions on cornea to realize the ablation model. Based on the principle of the correction for spherical myopia using small beam laser, our excimer laser corneal surgery system has been able to perform such refractive surgery. Now the corneal surgery system has been applied to clinical practice. Thirty-nine eyes with spherical myopia underwent LASIK using this kind of system. Their refractive states have been greatly improved. Preoperatively, the mean sphere was -5.57+/-2.95 D and the mean uncorrected visual acuity 0.12+/-0.07. One day after surgery, the mean sphere was -0.03+/-0.57 D and the mean uncorrected visual acuity 0.90+/-0.29. One month after surgery, the mean sphere was -0.68+/-0.98 D, and the mean uncorrected visual acuity 1.0+/-0.26.
Humans
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Lasers, Excimer
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Models, Biological
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Myopia
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surgery
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Photorefractive Keratectomy
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methods
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Treatment Outcome
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Visual Acuity
3.Research and implement of the primary motion simulation based on virtual articulator.
Ning DAI ; Yongyao ZHOU ; Wenhe LIAO ; Xiaosheng CHENG ; Qing YU
Journal of Biomedical Engineering 2007;24(5):1073-1078
This paper presents our work on the research process of virtual articulator simulation. Firstly, plaster models of upper jaw and low jaw are measured by 3D-optical measuring system and processed to get the available data. Secondly, complex physical modeling of the jaw motion is simplified and decomposed to a series of position transform, such as translation, rotation, etc.. Thirdly, opening/closing movement and laterotrusion is simulated by real-time updating display. Fourthly, the efficient collision detection algorithm is applied to dynamically compute occlusal contact regions and cutaway view. Finally, the current shortage of the virtual articulator simulation is discussed in detail and research prospect is forecasted.
Computer Simulation
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Dental Articulators
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Dental Occlusion
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Humans
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Imaging, Three-Dimensional
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Jaw
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physiology
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Models, Biological
4.Computer aided design and manufacture of individual laminate veneer.
Ning DAI ; Yexin NIU ; Qing YU ; Wenhe LIAO
Journal of Biomedical Engineering 2008;25(5):1029-1033
In view of the instance of a damaged medial incisor, we have introduced a method using computer aided technology to design and manufacture the laminate veneer. Firstly, the data on preparation teeth was retrieved by the 3D-optical measuring system. Secondly, the triangle mesh model of preparation teeth was reconstructed by using the reversion project software. And the 3D model of the laminate veneer was constructed through some operations, such as extracting the edge line of preparation teeth, mirroring the integrity incisor and local freeform transform. The result has proved that the fabrication process is reliable and efficient. The dental restoration quality is steady and precise. The artifical laminate veneer has met the request of esthetical symmetry.
Computer-Aided Design
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Crowns
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Dental Porcelain
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Dental Prosthesis Design
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Dental Veneers
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Humans
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Incisor
5.Research and application of computer-aided technology in restoration of maxillary defect.
Xiaosheng CHENG ; Wenhe LIAO ; Qingang HU ; Qian WANG ; Ning DAI
Journal of Biomedical Engineering 2008;25(4):762-765
This paper presents a new method of designing restoration model of maxillectomy defect through Computer aided technology. Firstly, 3D maxillectomy triangle mesh model is constructed from Helical CT data. Secondly, the triangle mesh model is transformed into initial computer-aided design (CAD) model of maxillectomy through reverse engineering software. Thirdly, the 3D virtual restoration model of maxillary defect is obtained after designing and adjusting the initial CAD model through CAD software according to the patient's practical condition. Therefore, the 3D virtual restoration can be fitted very well with the broken part of maxilla. The exported design data can be manufactured using rapid prototyping technology and foundry technology. Finally, the result proved that this method is effective and feasible.
Computer-Aided Design
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Humans
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Imaging, Three-Dimensional
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Maxilla
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diagnostic imaging
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injuries
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Maxillofacial Prosthesis
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Models, Theoretical
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Prosthesis Design
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Software
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Titanium
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chemistry
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Tomography, Spiral Computed
6.Segmentation of retinal blood vessels based on centerline extraction.
Lin ZHOU ; Jianxin SHEN ; Wenhe LIAO ; Yuliang WANG
Journal of Biomedical Engineering 2012;29(1):1-6
The precise estimation of blood vessel centerline and width is a prerequisite condition for the quantitative and visualized diagnosis of blood vessel disease in fundus images. In this paper, a retinal blood vessel segmentation algorithm based on centerline extraction is proposed. According to the characteristics of the fundus image and retinal blood vessels, the image is convoluted with the masks of discrete Gaussian partial derivative kernels. The centerline is determined by differential geometric properties of the blood vessels and the width is also calculated. The precision of our method can reach sub-pixel level with a fast computation speed. The experiments on several kinds of fundus images showed that the method worked quickly and accurately.
Algorithms
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Fundus Oculi
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Humans
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Image Enhancement
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methods
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Retinal Vessels
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anatomy & histology
7.Research of tool-path generation algorithm for NC machining dental crown restoration.
Quanping SUN ; Tongyue WANG ; Qianliang CHEN ; Ning DAI ; Wenhe LIAO ; Ning HE
Journal of Biomedical Engineering 2008;25(3):547-566
Seeing that the manual method to restore tooth has the disadvantages such as long "lead-time", assurance of quality highly depending on operator's technology, and real-time cure difficulty met by lots of dental patients coming up for tooth restoration, we put forward an algorithm of tool-path generation based on STL data model for roughing dental restoration. The algorithm can reconfigure the STL data of dental crown restoration quickly, can generates the multi-level offset wire-loop by the use of horizontal plane cutting triangle facets; and then on the basis of offset wire-loop, it can plan Zigzag and follow the contour machining tool path. The algorithm has been applied to Dental CAM software, through simulation machining, the result shows that it can not only generate interference-free tool path, but also save a lot of "lead-time" for dental restoration. Accordingly, the algorithm is of great value for reference in clinical application.
Algorithms
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Crowns
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Dental Restoration, Permanent
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methods
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Humans
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Software
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Therapy, Computer-Assisted
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methods
8.Computer aided design and manufacturing of the framework of PFM fixed bridge.
Tao AN ; Wenhe LIAO ; Qing YU ; Ning DAI ; Peijun LU ; Yong WANG
Journal of Biomedical Engineering 2008;25(2):235-240
We have carried out a research on the method for Computer Aided Design and Manufacturing (CAD/ CAM) of the framework of porcelain-fused-to-metal(PFM) fixed bridge. Taking the missing of the mandibular first molar as an example, firstly, we used ATOS II 3D scanner to collect the 3D data of the abutment teeth and used the acquried data to design the coping crowns. Secondly, the relevant standard bridge was selected from the standard bridges database and was deformed inaccordance to the characteristic of the patient. Then it was set to the correct position between the coping crowns automatically based on the restricting lines and faces. Finally, the connector was designed to connect the coping crowns and the bridge based on the touching area. The final product was manufactured by 3-axis NC milling machine. The results of examination showed that the framework of PFM fixed bridge fitted the abutment teeth very well, and the hardness of the connector and the precision of the whole model were feasible and reasonable. The method of designing and manufacturing the framework of PFM fixed bridge from CAD/CAM is practicable, efficient and accurate. It is also an important part of homemade dental CAD/CAM system.
Computer-Aided Design
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Crowns
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Dental Abutments
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Dental Prosthesis Design
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methods
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Denture, Partial, Fixed
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Humans
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Metal Ceramic Alloys
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Molar
9.Virtual orientation of the lower and upper jaws model on the position of centric occlusion.
Xiaosheng CHENG ; Wenhe LIAO ; Xiang ZHANG ; Qing YU
Journal of Biomedical Engineering 2007;24(6):1270-1273
The rotation axis equation of the simple articulator is built by the cylinder feature identification, which facilitates the rotation transform of the lower jaw data. Then the collision points and areas on the position of centric occlusion are found to form two collision couples. The virtual orientation of the lower and upper jaws model is realized by collision detection of the collision couples. Consequently the occlusal relation between the lower and upper jaws is established. It sets a good basis for the virtual adjustment of edentulous occlusal surface. The jaw movement of opening and closing in the state of hinge axis is also simulated accordingly.
Computer Simulation
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Computer-Aided Design
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Dental Articulators
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Dental Models
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Dental Occlusion, Centric
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Denture Design
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methods
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Humans
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Jaw
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physiology
10.The development of a system for 3D reconstruction from DICOM data and collaborative visualization.
Siyan LIU ; Wenhe LIAO ; Qing YU ; Xiaosheng CHENG ; Ning DAI ; Xiang ZHANG
Journal of Biomedical Engineering 2007;24(5):1152-1156
Complex surgeries often need multi-disciplinary surgeons to work collaboratively and set synthesized operation plans. Aided by collaboration enabled three dimensional visualization software over network, operation plans can be made more intuitively and accurately. Because different disciplinary surgeons often work at different locations, a distributed collaboration virtue environment over network should be provided. By our knowledge, such a system does not exist yet. Toward this, we implement a platform upon Client/Server architecture over network. The 3D model is reconstructed from CT image data of DICOM format and the resulting mesh is then simplified, using the Visualization Toolkit (VTK). The simplified polygon mesh data is further seamlessly integrated into our 3D graphics system developed with the HOOPS/3DAF for displaying, where the model is converted to the lossless compression stream file format-HSF, which is suited for network transmission. Using this format, a collaboration enabled interactive visualization system is implemented upon Client/Server architecture, developed with HOOPS/NET toolkit. The reconstructed 3D model is clear, and the interactive collaboration with 3D visualization is fairly real-time. We then implemented a platform for developing collaborative surgery simulation software, into which the surgery operation simulation and prosthesis design function can be easily added.
Computer Simulation
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Diagnostic Imaging
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methods
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Humans
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Image Enhancement
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methods
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Image Interpretation, Computer-Assisted
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methods
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Imaging, Three-Dimensional
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methods
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Internet
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Software
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User-Computer Interface