Objective To introduce a new purchase management model of hospital.Methods Through a narration and a deep analysis on current status of hospital purchase,some disadvantages were summed up and new suggestions and solutions were put forward so as to reform purchase model.According to the characteristics of military hospitals,commercial bribery in national medical industry was eliminated and medical costs were reduced.The broad masses of ordinary people could benefit from it.Results The facts of the new purchase management model of hospital were clarified and analyzed in an unique perspective,which were proved to be worthy of researching.Conclusion More detailed work should be done to implement the model.

Objective To introduce a new field-based operating astral lamp. Methods The operating astral lamp employs specially -designed LED as the main light source, and IC as the control circuit. All the components are arranged in a combinatorial structure. It uses no glass material and makes the most of light plastic materials instead of metal. Results By testing the use of it in field training, this astral lamp proves to possess the following traits that high efficiency of light-emitting and low heat and thermal radiation, small power consumption affording a long time of use, strong abilities for vibration and shock resistance, and light-weighted conformation and easy assembly providing a convenient portability. Conclusion It is very suitable for field patrolling and defending.

A systematic analysis of the typeⅢ secretion genes of Aeromonas hydrophila strain AH-1 by constructing ahyR and ahyI mutant revealed that they are under quorum-sensing control. This observation was supported by the down-regulation of the TTSS genes in the presence of lacZ-TTSS gene promoter and the corresponding advanced secretion of AexT in ahyI mutant.

Because of the increasing importance of medical equipment in hospital,medical equipment maintenance division,a department guaranteeing the normal performance of medical equipment,will also act as a vital way.This paper introduces some problems in the management of medical equipment maintenance division and analyses the reasons.Some ways and means are suggested to manage the medical equipment maintenance.

Objective To introduce a puncture-drainage system for intracranial hematoma, which can be used in both peacetime and wartime. Methods The inserting-style connections were taken to design the catheter needle and driller. In the design of the combined T-piece, silica membrane was used to be the main sealing end. The fixed division between the main sealing end and the catheter needle took thread connections. The angle between the side-tube of the T-piece and the catheter needle was 120 degree; the side-tube of the T-piece and the Y-tube also took thread connections. The another two sides of Y-tube linked to different drainage bag and syringe, and all of the hoses got the individual and portable switches. Results This system was more efficient, rapid, safe and convenient. What's more, the injury was minimal when doctor performed an intracranial hematoma puncture surgery by using the puncture-drainage system. Conclusion It is very easy to operate and suitable to puncture drainage for intracranial hematoma surgery in both peacetime and wartime.

Objective To provide evidence for control and prevention of hand-foot-mouth disease(HFMD) ,we analyzed the epi-demiological and viral characteristics of HFMD in Yongchuan district from 2009 to 2012 .Methods We collected the clinical dates of HFMD cases from Diseases Infectious Department of the Yongchuan Affiliated Hospital of Chongqing Medical University during 2009 to 2012 ,and analyzed the epidemiological characteristics .Results There were 509 HFMD cases in recruitment ,including 2 se-vere cases(one was dead) .The peak incidence of HFMD occurred from May to July annually .Between 2011 and 2012 ,there was an-other peak incidence ,which occurred from November to December .Most of the patients were under 5 years-old .The number of male cases was larger than that of the female .The number of scattered children cases was larger than that of the nursery children .More cases were reported in rural area than in urban area .Coxsackie virus A16(Cox A16) and other enteroviruses were the predominant strains of HFMD ,however enterovirus 71(EV71) infected cases increased sharply between 2011and 2012 .Enterovirus 71(EV71) inflection is the main cause of severe and death of HFMD .Conclusion The prevalence of HFMD in Yongchuan district had signifi-cant seasonal ,sex and age-specific ,regional differences and etiological characteristics .It was very important to make practical man-agements to prevent occurrence of HFMD according to these epidemiological characteristics .

Objective To evaluate the effects of health education of house-to-house visit in malaria prevention and control in the border and minority areas. Methods A health education of house-to-house visit in malaria prevention and control was car-ried out,and baseline and follow up surveys were conducted by qualitative and quantitative methods to document the changes of local villagers’knowledge,attitudes and behaviors(KAP)of malaria prevention and control in 2 counties of Yunnan Province, and the results before and after the interventions were analyzed and compared. Results After the intervention,the cognition rates about malaria symptoms and signs,transmission mode,preventive measures and health-seeking behaviors were 99.3%, 98.9%,79.9%and 99.3%respectively in the local residents,and those were 39.2%,8.2%,47.0%and 49.9%respectively be-fore the intervention,and all the differences were statistically significant(P all<0.01). Conclusions KAP related to malaria among the targeting population has improved after the interventions and the house-to-house visit is an effective community-based health education approach.

Objective To design an endoscopic image acquisition system.Methods High resolution CCD image sensor was used as the image acquisition equipment to converse the optical signals into electrical ones. Data were stored with FPGA controller after ADC, and then transmitted to the computer with PCI bus,Results Trials proved that the system could acquire clear and stable image with simple structure and easy operation.Conclusion The system can acquire high-quality images for the diagnosis and treatment of endoscope.

Objective To investigate the value of perfusion CT in the evaluation of neoadjuvant chemotherapy in locally advanced squamous cell carcinoma.Methods Sixty-seven patients with Ib2-IIb squamous cell carcinoma of the cervix underwent CT perfusion imaging before neoadjuvant chemotherapy to measure blood flow (BF),blood volume (BV),peak time (MTT),permeability sur-face (PMB),perfusion time to peak (TTP)and MIP(HU);and underwent routine enhancement CT after the two course of neoadju-vant chemotherapy treatment to measure tumor size,and evaluate the therapeutic effect.Results Among 67 patients,48 patents were effective (2 completely remission and 46 partial remission),and 1 9 patients were ineffective (1 5 stable and 4 progressed),with the overall response rate of 71.6%.The differences of PMB and BV value between effective and ineffective group were statistically significant before neoadjuvant chemotherapy (P <0.001).The BF,MTT,TTP value were no significant difference between effec-tive and ineffective group before neoadjuvant chemotherapy (P >0.05).The BV and PMB value were relatively higher in the patients with effective chemotherapy.Conclusion CT perfusion imaging could measure the BV and PMB value of the tumor before neoadju-vant chemotherapy to provide the basis for treatment selection.

Objective To study the changes and significance of sCD14 in inflammatory response of patients with gouty arthritis.Methods CD14 mRNA was measured using quantitative real-time PCR in peripheral blood mononuclear cells (PBMCs).The expression of CD14 mRNA in PBMCs was compared between patients with acute gouty arthritis (AGA)(n =31)and non-acute gouty arthritis (NAGA)(n =23)and healthy controls (HC)(n =20).β-actin was selected as the internal control.The protein expressions of sCD14,IL-1βand TNF-αwere measured using enzyme linked immunosorbent assay (ELISA) in patients’ plasma.The protein expression of CRP was measured using immunoturbidimetry in patients’ plasma. Routine blood and blood biochemistry indexes were measured by routine blood analyzer and blood biochemistry analyzer of patients with AGA,NAGA and HC.We analyzed the correlation between CD14 mRNA,sCD14 protein expression and each clinical indicator.Results When compared with that in AGA group,the mRNA expression of CD14 increased significantly in PBMCs of HC patients (P < 0.05 ).When compared with that in HC and NAGA patients,the protein expression of sCD14 increased significantly in the plasma of AGA patients (P <0.01).The protein expression of sCD14 was significantly lower in the plasma of NAGA than in HC (P <0.05).The protein expression of sCD14 increased significantly in the plasma of AGA compared with HC and NAGA (P < 0.01 ).When compared with those in HC,the protein expressions of IL-1β and TNF-α increased significantly in the plasma of AGA and NAGA (P < 0.01 ).When compared with that in NAGA,the protein expression of IL-1βincreased significantly in plasma of AGA (P <0.01). The indexes of WBC increased significantly in AGA compared with HC (P <0.01),and WBC increased significantly in NAGA compared with HC (P <0.05).The indexes of GR and MO increased significantly in AGA compared with HC (P <0.05),and MO increased significantly in AGA compared with NAGA (P < 0.05 ).The indexes of UA increased significantly in AGA and NAGA compared with HC (P <0.01).There was a positive correlation between CD14 mRNA expression and IL-1β in PBMCs in AGA group (r s =0.362,P =0.045).A positive correlation was found between GR and the protein expression of sCD14 in NAGA patients’plasma (r s = 0.397,P = 0.030 ). Conclusion The dysregulated expressions of CD14 mRNA in PBMCs and sCD14 protein in GA show that sCD14 may play a significantly regulatory role in inflammatory reaction.