1.Micro-invasive evacuation for treatment of cerebral hemorrhage
Chinese Journal of Primary Medicine and Pharmacy 2008;15(z1):16-17
Objective To evaluate the dfect of micro-invasive evacuation for treatment of cerebral hemorrhage.Methods Eighty patients with cerebral hemorrhage were treated by the micro-invasive surgery.Results The hematoma was evacuated between 1~5 days in 55 cases,7 dyas in 24 cases and 14 days in 1 case.The total effeetive rate was 81%.Seyen cases died.Modified rankin scale(MRS)0~1 was found in 21 cases,MRS 2~3 was found in 44 cases,MRS 4~5 in 8 cases.Conclusion Compared with the medical conservative treatment,the microinvasive evacuation for treatment of brain hemorrhage could significantly reduce patients'hospitalization time,morbidity and mortality.At the same time indication are relatively extensive,complications are less.
2.The relationship between the degree of intracranial and extracranial arterial stenosis and the plasma level of homocysteine in patients with ischemic cerebrovascular disease
Wenguang BU ; Kun QIAN ; Tao WANG
Chinese Journal of Primary Medicine and Pharmacy 2014;(15):2312-2314
Objective To study the relationship between the degree of intracranial and extracranial arterial stenosis and the plasma level of homocysteine ( Hcy ) in patients with ischemic cerebrovascular disease .Methods 96 patients with ischemic cerebrovascular disease were checked by DSA .The distribution of stenosis in the studied cerebral arteries was analyzed .According to the degree of stenosis ,all 96 patients were divided into some groups ,at the same time Hcy level was detected ,and the correlation between Hcy level and intracranial and extracranial artefial stenosis were analyzed .Results 35 of the 96 patients had normal findings in angiography ,and 61 cases had occlusive lesions of different degrees .The mean plasma Hcy concentration in patients with intracranial and extracranial arterial stenosis was 19.26 (14.79~26.13)μmol/L,which was significantly higher than 11.60(8.8~15.11)μmol/L in the patients with no arterial stenosis (P<0.05).There was a significant positive correiation between Hcy level and cerebral artery stenosis degree(r=4.126,P<0.05).Conclusion The plasma Hcy level was positively correlated with intracranial and extracranial arterial stenosis in patients with ischemic cerebrovascular disease ,incidence and nar-row-degree of cerebral artery stenosis are all along with the increasing of Hcy level .
3.Clinical analysis of the cerebral DSA in 99 patients with ischemic cerebrovascular disease
Tao WANG ; Diangui KANG ; Wenguang BU ; Kun QIAN
Chinese Journal of Primary Medicine and Pharmacy 2014;(21):3254-3256,3257
Objective To explore the distribution of vascular lesions in the cerebral digital subtraction angi-ography( DSA) and associated diseases in patients with ischemic cerebrovascular disease( ICVD) ,and complications, as well as the value of DSA in ICVD.Methods The DSA data of 99 ICVD cases were analyzed retrospectively, patients treated by ischemia type were divided into the cerebral infarction(CI) and transient ischemic attack(TIA) group.All patients were examined by 3D-TOF and neck vascular ultrasound screening,the final diagnosis by DSA. While observing the perioperative complications and associated diseases.Results 99 patients with ICVD,88 cases of the presence of vascular lesions diagnosed by DSA.In 99 cases,there were 252 lesions,accounting for the top three for the internal carotid artery(ICA),vertebral artery(VA) and the middle cerebral artery(MCA).While there were 121 bifurcation lesions,accounting for the top three for ICA,VA,and the external carotid artery(ECA).TIA in patients with concomitant diseases accounted for the top three for hypertension(HTN),type 2 diabetes mellitus(T2DM) and hyperlipidemia and renal insufficiency;Patients with CI associated diseases accounted for the top three for HTN, T2DM and hyperlipidemia.There were 10 cases of patients with DSA complications,most of the vasovagal reflex in five cases;serious for TIA and CI in 1 case ( not cause any neurological deficits at discharge ) .Conclusion Carotid vascular disease plays an important role in the occurrence of ICVD, especially in the blood vessels of bifurcation lesion.Within ICVD risk factors in HTN in the majority, followed by T2DM, hyperlipidemia.DSA surgery rarely serious complications,blood vessels can provide more comprehensive information,and provide the basis for further development of ICVD prevention and treatment programs,this checking method is safe and reliable.