1.Rapid Analysis of Three Kinds of Pesticide Residues by Non-contact Thermal Desorbing and Closing Low Temperature Plasma Ionization Mass Spectrometry
Mingyang SU ; Keyong HOU ; Zejian HUANG ; You JIANG ; Wendong CHEN ; Ping CHEN ; Jichun JIANG ; Wuduo ZHAO ; Kemei PEI ; Haiyang LI
Chinese Journal of Analytical Chemistry 2014;(3):384-389
A new method was established for the direct, rapid and quantitative analysis of pesticide residues, dimethoate chlorothalonil and malathion by low temperature plasma ( LTP) ionization miniature ion trap mass spectrometer. The LTP ionization probe and sample inlet of ion trap mass spectrometry were enclosed in a metal cavity. With non-contact heating, the samples placed on the sample platform were desorbed into gaseous phase and ionized by LTP ionization probe. The results showed that closed ionization had an edge over the opened ionization. The quantitative analysis of 3 pesticides within the range of 0. 5-10 mg/L was realized by optimizing heating time and flow rate of air, and the relative standard deviations of signal intensity is less than 11%. LODs of pesticide, which were obtained within 5 s, were as low as several hundred pictograms. The results showed that the method could be used for the analysis of pesticide residue on green and organic fruits or vegetables.
2.Amplitude-Integrated Electroencephalography Predicts Outcome in Patients with Coma After Acute Brain Injury.
Wendong YOU ; Qilin TANG ; Xiang WU ; Junfeng FENG ; Qing MAO ; Guoyi GAO ; Jiyao JIANG
Neuroscience Bulletin 2018;34(4):639-646
Prognostication of coma patients after brain injury is important, yet challenging. In this study, we evaluated the predictive value of amplitude-integrated electroencephalography (aEEG) for neurological outcomes in coma patients. From January 2013 to January 2016, 128 coma patients after acute brain injury were prospectively enrolled and monitored with aEEG. The 6-month neurological outcome was evaluated using the Cerebral Performance Category Scale. aEEG monitoring commenced at a median of 7.5 days after coma onset. Continuous normal voltage predicted a good 6-month neurological outcome with a sensitivity of 93.6% and specificity of 85.2%. In contrast, continuous extremely low voltage, burst-suppression, or a flat tracing was correlated with poor 6-month neurological outcome with a sensitivity of 76.5% and specificity of 100%. In conclusion, aEEG is a promising predictor of 6-month neurological outcome for coma patients after acute brain injury.
Brain
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physiopathology
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Brain Injuries
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complications
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diagnosis
;
physiopathology
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Coma
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diagnosis
;
etiology
;
physiopathology
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Electroencephalography
;
methods
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Female
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Follow-Up Studies
;
Humans
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Male
;
Middle Aged
;
Neurophysiological Monitoring
;
methods
;
Prognosis
;
Prospective Studies
;
Sensitivity and Specificity
;
Severity of Illness Index