1.Clinical effect and adverse reaction of tiggio combined with oxaliplatin on the treatment of advanced gastric
Chinese Journal of Biochemical Pharmaceutics 2017;37(9):290-292
Objective To explore the clinical effect and adverse effects of tiggio combined with oxaliplatin on the treatment of advanced gastric cancer. Methods From January 2014 to January 2017, 88 cases with advanced gastric cancer were selected as the samples in Yangling demonstration zone hospital. All the patients were randomly divided into the control group (n = 44) and the observation group (n = 44). The control group and the observation group were treated with tiggio and tiggio combined with oxaliplatin respectively, and the clinical effect and the occurrence of adverse reactions in the two groups was compared. Results The total effect in the observation group was 91.0%, which was significantly higher than that in the control group (75.0%), (P<0.05); The incidence of adverse reactions in the control group was 27.3%, while in the observation group was 9.1% the difference was statistically significant(P<0.05). Conclusion Tiggio combined with oxaliplatin in the treatment of advanced gastric cancer, the clinical effect is significant, the incidence of adverse reactions is low, high security, worthy of promotion.
2.On the achievement of comprehensive control targets among type 2 diabetic patients managed by communities in Jiangsu province
Jian SU ; Yu QIN ; Chong SHEN ; Yan GAO ; Enchun PAN ; Wencong DU ; Jinyi ZHOU ; Yongqing ZHANG ; Ming WU
Chinese Journal of Endocrinology and Metabolism 2018;34(2):112-120
Objective To explore the control levels of blood glucose,blood lipid,blood pressure(BP),and body mass index(BMI)in the community-managed patients with type 2 diabetes in Jiangsu and to provide the basis for better management of type 2 diabetes in communities. Methods From December 2013 to January 2014,20 053 patients with type 2 diabetes and have received disease management according to the National Basic Public Health Service were recruited in Changshu County of Suzhou City, Huai'an and Qinghe Districts of Huai'an City. Questionnaire survey, anthropometric and laboratory measurements were conducted. According to the Chinese guidelines for type 2 diabetes prevention and treatment(2013),the control levels of blood glucose,blood lipid,BP, and BMI were assessed. Results Among 20 053 patients with type 2 diabetes,the proportions for controlled fasting plasma glucose(FPG) and HbA1Cwere 31.4% and 41.9% respectively,and 25.3% of the patients simultaneously achieved goals of FPG and HbA1Ccontrol. There were 23.9%,55.7%,75.5% and 24.2% of the patients met goals for total cholesterol (TC), triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol(LDL-C), respectively. Only 10. 3% of the patients achieved all the 4 targets of blood lipid. Furthermore,there were 25.4% and 35.9% patients achieved BP and BMI targets respectively,and the control rates for BP and BMI of females were higher than those of males(all P<0.05). Less than 1% of the patients had all eights indices controlled at target levels. Conclusions The achievement of comprehensive targets among community patients with type 2 diabetes remains poor in Jiangsu. Follow-up and management of type 2 diabetes should be strengthened in communities,health education and comprehensive intervention on disease complications should also be reinforced accordingly.