1.The impact of simvastatin combined with trimetazidine on cardiac function and high-sensitivity C-reactive protein in patients with chronic heart failure
Chinese Journal of Primary Medicine and Pharmacy 2013;20(20):3116-3118
Objective To study the effect of simvastatin combined with trimetazidine on cardiac function and high-sensitivity C-reactive protein(hs-CRP) in patients with chronic heart failure.Methods 160 patients with chronic heart failure were divided into control group and the observation group according to the random number table.The control group was treated with diuretics,inotropic,vasodilators and other conventional treatment,on the basis of this,the observation group received simvastatin combined with trimetazidine treatment.The cardiac function and hs-CRP of the patients were observed,and the treatment effects were evaluated and analyzed.Results The total effective rate of the observation group was 82.50%,which was significandy higher than 52.50% of the control group (x2 =16.4103,P < 0.001).Compared with before treatment,IL-6,TNF-alpha and hs-CRP levels of two groups after treatment were significantly decreased (t =12.234,13.342,5.463,8.533,7.896,3.536,all P < 0.05),and those in the observation group were significantly lower than the control group (t =4.653,3.976,3.674,all P < 0.05).Conclusion Simvastatin combined with trimetazidine has good effect on the cardiac function of patients with chronic heart failure,and can effectively reduce the level of hs-CRP,it is worthy of clinical application.
2.A study on psychology-behavior characteristics in serious internet game addicts
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(6):484-486
Objective To explore the mental-behavior characteristics in serious internet game addicts.Methods To investigate internet addiction questionnaire, EPQ, social support questionnaire, purpose in life test and sensation seeking scale in 30 serious internet game addicts ( age from 16 ~ 25 years) and 43 non-addicts.Results Internet addicts have obviously lower social support questionnaire score, subjective support score, purpose in life test score and sensation seeking TAS score than non-addicts( P<0.05 or P<0.01 ). Objective support score, the use score for social support and sensation seeking score can forecast the internet addiction extent of the internet addict group. Internet addicts have obviously lower L score of EPQ than non-addicts ( P<0.01 ). There is the negative correlation between N score of the internet addicts and sensation seeking score( r=-0. 452, P<0.05). Conclusions Serious internet game addicts have the metal characteristics of low social support, low purpose in life and low adventure; sensation seeking and social support scale have prognosticative function for internet addiction degree; serious internet game addicts of low N score have high sensation seeking characteristic.
3.The development of lottery addiction scale for Chinese lottery buyers
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(8):757-759
Objective This study aims to develop a lottery addiction scale (LAS) for Chinese welfare lot-tery buyers. Methods A scale made by authors was applied to 8238 welfare lottery buyers from 31 provinces,one sample of 4071 cases for exploratory factor analysis (EFA) ,and the other 4167 cases for confirmatory factor analy-sis (CFA). Results Through EFA, the scale consisted 10 items established, and it was divided into two factors: functional impairment and emotional dependency. These two factors could explain 45.5% of total variance, The scale was confirmed by CFA (X2/df=13.34 ;IFI=0.96 ;CFI=0.96 ;NFI=0.96 ;RSMEA = 0.054). The internal consistencies of the scale answered to the basic statistic criterion (r=0.59~0.74). Criteria validity shown by higher LAS scores in high expending group than low expending group was also satisfying. Conclusion The LAS has good psychometric features and could be applied to Chinese lottery buyers.
4.Early Face Processing of Internet Addiction Patients by Face-specific N170
Space Medicine & Medical Engineering 2006;0(01):-
Objective To study early face processing of internet addiction patients by using ERP method. Methods Ten healthy young man 18~21 years and 10 internet addiction patients 17~22 years served as subjects in experiment. Two runs of 300 stimuli (duration: 50 ms) of 3 facial and 3 non-facial pictures were randomly presented with equal probability (ISI: from 1 000 ms to 1 500 ms randomly), and the subjects were asked to react to facial stimuli and non-facial stimuli by pressing the left button and right button respectively as quickly as possible. Thirty two channel electroencephalogram (EEG) was recorded by Neuroscan Nuamps System. Results 1) Specific-face component Nd170 (face N170 minus object N170) was found in both groups, which was distributed at the temporal-occipital region in control groups but at occipital region in internet addiction group; 2) Compared with Nd170 in internet addiction group, Nd170 was significantly lower at occipital negion and delayed in control group. Conclusion The early face processing mechanism of internet addiction patients may be different from normal people.
5.The effects on psychological health of patients with hearing loss.
Beier QI ; Bo LIU ; Wenbin GAO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(19):1533-1536
Previous studies have shown that hearing loss people are more likely to have not only abnormal speech communication, but also psychological problems especially emotional disorders, cognitive impairments and personality defects. Therefore, it is necessary to provide psychological support to patients during they accept medical therapy.
Communication
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Hearing Loss
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complications
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psychology
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Humans
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Mental Disorders
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Mental Health
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Speech
6.Reliability and Validity of a Questionnaire on Knowledge, Beliefs and Intentions related to AIDS/Safe Sex for University Students
Xinying SUN ; Wenbin GAO ; Chun CHANG
Chinese Mental Health Journal 1988;0(06):-
Objective: To test the reliability and validity of a questionnaire on knowledge, beliefs and intentions about AIDS/safe sex for university students. Methods: Based on the data investigated with this questionnaire from 598 university students and the test-retest data from 63 university students, the internal consistency, test-retest reliability and construct validity were calculated. Results: This questionnaire had good reliability, with most parts having Cronbach ? coefficients large than 0.7 and retest coefficients large than 0.6. The factor structure was consistent with the theoretical hypothesis and the factors could explain 58.85% of the whole questionnaire.Conclusion:This questionnaire can be applied among university students to assess AIDS/safer sex related knowledge, beliefs and behavioral intentions.
7.Lymph node failure pattern after radiotherapy/chemotherapy in esophageal squamous cell carcinoma without initial clinical metastasis
Hongmei GAO ; Guowei XIAO ; Shuping CHI ; Wenbin SHEN
Chinese Journal of Clinical Oncology 2015;(9):466-470
Objective:To analyze the factors affecting lymph node failure pattern after radiotherapy/chemotherapy in esophageal squamous cell carcinoma without initial clinical metastasis. Methods:A total of 263 patients, who were diagnosed as thoracic esopha-geal carcinoma from January 2002 to December 2009, were included in this retrospective study. Factors affecting lymph node failure pattern with general clinical data and tumor local factors were analyzed. Results:Among the 263 esophageal cancer cases, 31 (11.8%) had lymph node metastasis after treatment, including 18 cases of simple lymph node metastasis and 13 other cases of lymph node metas-tasis with esophageal and other organ metastasis or recurrence. The numbers of cases for lymph node metastasis in the upper, middle, and lower thoracic esophagus were 11 (13.3%), 13 (10.1%), and 7 (13.7%), respectively. Univariate analysis showed that recent cura-tive effect, length of tumor on X-rays, maximum tumor diameter, and tumor volume were the significant factors associated with lymph node metastasis (χ2=7.597, 9.717, 5.361, and 4.815;P=0.006, 0.002, 0.021, and 0.028). Logistic regression analysis results showed that recent curative effect and length of tumor on X-rays were independent significant factors (P=0.004 and 0.026). Conclusion:Recent cu-rative effect and length of tumor on X-rays were the significant factors associated with lymph node failure pattern after radiotherapy/chemotherapy in esophageal squamous cell carcinoma without initial clinical metastasis.
8.Clinical study of relationship between sleep apnea syndrome and metabolic syndrome of petrol field workers
Zhisong YANG ; Ting TAO ; Min LIU ; Hongxia BAO ; Wenbin GAO
Chinese Journal of Emergency Medicine 2016;25(6):802-805
Objective To analyze the relationship between obstructive sleep apnea syndrome (OSAS) and metabolic syndrome (MS) in petrol field workers.Methods A total of 100 cases of OSAS patients of petrol field workers were enrolled as the study objects from March 2013 to August 2015 in emergency and respiratory department in Daqing Longnan Hospital and were divided into three groups:simple snoring group (Group A,n =26),mild OSAS group (Group B,n =42),and severe OSAS group (Group C,n =32).The comparison of dietetic status score,sleep status score and the patients with MS among 3 groups were carried out.The relationship between OSAS and MS was analyzed by using univariate and multivariable Logistic regression analyses were used.Results In Group C,sleep status score (8.3 ± 1.2) and dietetic status score (7.6 ± 1.4) and the rates of MS (23/32) were higher than those in the other two groups (P < 0.05).Univariate and multivariable Logistic regression analyses,showed OSAS was the risk factorofMS [r=11.211 (OR =9.412,95% CI:5.992~15.202)].Conclusions Dietetic status and sleep status were obviously influenced by OSAS in petrol field workers.The incidence of MS were more common in petrol field workersevere with OSAS and OSAS was a risk factor of MS.
9.Relationship between physical and mental health and self-control of elderly people in nursing home
Xiaoli YU ; Ting TAO ; Ligang WANG ; Wenbin GAO
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(7):638-641
Objective To explore the relationship between self-control ability and physical and mental health of the elderly people in nursing home.Methods 183 elderly people from three nursing homes were investigated using self control measurement method of dual system scale and World Health Survey.The individuals were divided into high control low impulsiveness group(n=51),high control high impulsiveness group(n=36),low control low impulsiveness group(n=27) and low control impulse group(n=69).Results The total score of physical and mental health for elderly people in nursing homes was.(1.76±0.46),while the scores of body health,mental health and overall self evaluation were (1.84± 0.56),(1.66± 0.42) and (2.93±0.72).The scores of physical health and mental health for elderly people in nursing homes of impulse and control system for elderly people in nursing homes were (2.98 ± 0.63) and (3.35 ± 0.59).The scores of physical health (r=0.15),mental health (r=0.29) and overall self evaluation (r=0.31) were positively correlated with impulse system,and negatively correlated with control system (r=-0.26,-0.33,-0.34,P<0.05).The scores of physical health,mental health and overall self evaluation in four groups were significantly different (F=12.39,33.82,21.50,P<0.01).Conclusion The physical and mental health of the elderly people in nursing home is correlated with self-control ability.
10.Clinical Study on Acupoint-injecting Method for Marrow Inhibition Caused by Chemical Medications
Jianqing DOU ; Hui ZHANG ; Wenbin GAO ; Liangwei YIN
Journal of Acupuncture and Tuina Science 2006;4(2):84-86
Purpose:In order to explore the feasibility and efficacy of acupoint-injecting method for marrow inhibition caused by chemical medications. Methods: 110 cases of malignant tumors in the phase of marrow inhibition after arterial chemotherapy were treated by puncturing the acupoints, Zusanli (ST 36), Sanyinjiao (SP 6), Xuehai (SP 10) and Qihai (CV 6) plus injection of 5 mg dexamethasone. Results: Acupuncture treatment and acupuncture plus injection of medications can both effectively improve marrow inhibition after chemotherapy, and the therapeutic effect was better in the group by acupuncture plus acupoint-injecting method. Conclusion: Acupuncture can effectively stimulate the acute and short-term marrow inhibition caused by chemical medications, and acupuncture plus acupoint-injecting method can effectively shorten the treatment time and the lower hemogram phase of peripheral blood. The combination of two therapeutic methods can have remarkable cooperative effect and reduce the medical expenses.