1.The relation of vascular endothelial growth factor and angiogenesis to the progression of colorectal carcinoma
Wen LEI ; Xigeng ZHOU ; Baoming YU
Chinese Journal of Digestion 2001;0(08):-
Objective To investigate the relation of vascular endothelial growth factor (VEGF) and angiogenesis to the progression of colorectal carcinoma (CC). Methods VEGF protein expression and microvessel density (MVD) in 102 cases of human CC were examined by use of immunohistochemical staining. MVD and VEGF expression were analysed with their relation to histological grade, depth of invasion, Dukes stage, lymph node metastasis, liver metastasis and prognosis of CC. Results MVD was significantly higher in VEGF positive CC than in VEGF negative CC ( P
2.Value of tumor angiogenesis for the prognosis of patients suffering from colorectal carcinoma without metastasis at the time of laparotomy
Wen LEI ; Baoming YU ; Xigeng ZHOU
Chinese Journal of General Surgery 2001;0(10):-
ObjectiveTo determine the prognostic value of angiogenesis in non-metastatic colorectal carcinoma at the time of laparotomy.Methods Microvessel counts(MVC) of 58 specimens were investigated by immunohistological staining with a monoclonal antibody against F-Ⅷ RAg. Correlation between MVC, clinicopathologic factors, postoperative local recurrence, and liver metastasis was evaluated.Results MVC correlated positively with postoperative local recurrence(P21, the risk of liver metastasis and local recurrence significantly increased. MVC also correlated with prognosis (P
4.Changes of Serum Levels of N-Terminal Pro-Brain Natriuretic Peptide in Children with Congestive Heart Failure Complicated with Different Pathogeny and Its Relationship with Pulmonary Hypertension
hai-ying, ZHOU ; hua-feng, YU ; xiao-wen, ZHOU
Journal of Applied Clinical Pediatrics 1992;0(06):-
0.05).Conclusions Serum NT-proBNP level is sensitive and specific for the diagnosis of pneumonia complicated with CHF and CHD complicated with CHF. There is an increasing tendency of NT-proBNP level companied increasing pulmonary pressure.
5.Survey on the knowledge, attitudes and behavior for foodborne disease in medical staff
Zhi CHEN ; Zihang ZHU ; Wen ZHOU ; Shaozhen YU
Chinese Journal of Behavioral Medicine and Brain Science 2014;23(2):159-161
Objective To investigate the knowledge,attitude and behavior of medical staffs on foodborne diseases.Methods To investigate the knowledge,attitude and behavior of medical staffs on foodborne diseases by random sampling following the questionnaire.Results There were 332 medical workers attending the survey.The medical staffs were lack of knowledge for foodborne disease,percent of pass was 34.33%.The pass rate of attitude and behavior were 88.88% and 98.19%.The knowledge score of medical staff of top three hospital (6.49± 2.18)were lower than the community health service center(7.04±2.26) (P<0.05),but attitude and behavior score of this two staffs had not statistical differences(P>0.05).Conclusion It is necessary to help medical staff to improve the attitude of foodborne diseases,and improve the monitoring of underreporting case.
6.Clinical study of occupational therapy in conjuct with Taoist cognitive psychotherapy on emotional disorder in rehabilitation of hemiplegic stroke patients
Hai-Yun ZHOU ; Jing-Wen XI ; Chun-Yu WANG ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(09):-
Objective To evaluate the effects of occupational therapy and Taoist cognitive psychotherapy on emotional disorder of stroke patients.Methods A total of 136 hemiplegic patients with emotional disorder were randomly divided into a general treatment group,a cognitive psychotherapy group,an occupational therapy group and a combined therapy group(occupational therapy combined Taoist cognitive psychotherapy group).All patients were treated accordingly for 8 weeks and followed up for 6 months.All the patients were evaluated with Fugl-Meyer Assess- ment,COPM and SCL-90.Results It was found that the Fugl-Meyer Assessment and COPM scores were improved gradually in all groups.The combined therapy group scored higher than occupational therapy group(P
8.Survey on the symptoms and risk factors in patients with hypertension.
Wen-quan ZHOU ; Xiang-dong YU ; Ling CUI
Chinese Journal of Integrated Traditional and Western Medicine 2002;22(6):457-458
Adult
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Aged
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Cerebral Infarction
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etiology
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China
;
epidemiology
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Coronary Disease
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diagnosis
;
etiology
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Diagnosis, Differential
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Female
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Humans
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Hypertension
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complications
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diagnosis
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epidemiology
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Logistic Models
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Male
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Medicine, Chinese Traditional
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Middle Aged
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Risk Factors
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Yin Deficiency
;
diagnosis
9.Probe melting curve analysis-based PCR assay for the rapid detection of non-deletionα-thalassemia(αT)
Xing CHEN ; Qizhi XIAO ; Wen YU ; Yuqiu ZHOU ; Jianhong XIE
International Journal of Laboratory Medicine 2015;(14):2009-2010,2012
Objective To investigate the clinical value of the probe melting curve analysis‐based PCR assay for the detection of three types of αT .Methods A total of 149 blood and prenatal archival DNA samples (6 of which were amniotic fluid samples)with three knownαT genes ,which included 63 carriers with Hb CS ,22 cases with Hb QS ,43 individuals with Hb WS and 1 double heter‐ozygote with Hb CS and Hb WS) as well as 20 samples with normalα‐globin gene sequence that had been confirmed by RBD com‐bined with DNA sequencing were selected to test the specificity of probe melting curve analysis by blind analysis .Results The probe melting curve analysis accurately detected 100 of the DNA samples previously characterized by S RBD combined with DNA sequencing .Conclusion Probe melting curve analysis‐based PCR assay for the detection ofαT is featured with rapidity and accuracy and can be applied to clinical and prenatal diagnosis .