2.A forgotten swab in bronchus for 19 years.
Dian-Dian LI ; Yong-Chun SHEN ; Fu-Qiang WEN
Chinese Medical Journal 2013;126(6):1118-1118
Bronchi
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pathology
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Bronchoscopy
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Female
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Foreign Bodies
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diagnosis
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Humans
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Middle Aged
5.Relationship Between the Angiotensin-Converting Enzyme 2 Genotype and Effect of Irbesartan on Left Ventricular Structure and Function in Hypertensive Patients
Cao-Jin ZHANG ; Fu-Rong CHEN ; Zhi-Xin SHAN ; Yong-Heng FU ; Wen-Jun YI ; Dong-Li CHEN ;
Chinese Journal of Hypertension 2006;0(12):-
Background Experimental data have shown tnat polymorpnisms in tne angiotensm-converting en- zyme 2(ACE2)gene are related to echocardiographically determined parameters of left ventricular mass,structure or function in the general population whether ACE2 genotype influences the effect of angi0tensin Ⅱ receptor blocker which improve left ventricular remodeling and function is unknown.Objective To investigate the association be- tween ACE2 gene G9570A polymorphism and the effect of irbesartan on left ventricular structure and function in hy- pertensive patients.Methods Two hundred and five male patients and 190 female patients who were preliminaryly diagnosised with mild and moderate essential hypertension were treated with irbesartan for 48 weeks with initial dose of 150 mg/d and titrated to 300 mg/d to reach the targed BP.Gene polymorphisms of ACE2 G9570A were detected by PCR-RFLP methods.The association between changes in the SBP,DBP,parameters of left ventricular struc- ture and function and genotypes of the ACE2 gene locus were analyzed.Results Irbesartan reducted in blood pres- sure in all patients(P
8.Optimization of Cultural Conditions of Probiotic Bacteria Lactobacillus casei Zhang for High Cell Density Cultivation
Yan LI ; Wen-Jing ZHAO ; Peng-Fei GAO ; He-Ping ZHANG ; Yong-Fu CHEN ;
Microbiology 1992;0(02):-
To get high cell density,pH-stat fermentations of L.casei Zhang were carried out in the medium optimized previously under different cultural conditions.The influences of neutralizing agents,the concen-tration of buffer salts and glucose in the medium,pH,aeration and fed batch fermentation on the growth of L.casei Zhang were investigated.Based on the values of maximum specific growth rate,biomass and viable cells count in different cultural conditions,the optimal growth condition was regarded as follows:Glucose level of the medium was 80 g/L ~100 g/L;The pH was kept constant at 5.9 with aqua ammonia and anae-robic condition was kept by sparged with nitrogen periodically;The temperature was set at 37?C and cul-tured for 10 h ~12 h.The biomass and viable cells' number of L.casei Zhang under this culture conditions were 7 g/L and 3.5?1010 CFU/mL respectively,and were 7 times as high as that before optimized,which can meet the requirements of probiotics.
9.Effect of bcl-xi overexpression in transgene mice with cerebral infarction and study of cytochrome Cexpression and caspase-3 expression
Fu-Rong WANG ; Yong-Sheng JIANG ; Yan LIU ; Wen-Wu XIAO ; Su-Ming ZHANG ;
Chinese Journal of Emergency Medicine 2006;0(09):-
0.05).At different time points after ischemia-reperfusion,the expression of cytochrome C and activation of caspase-3 were lower in the transgen mice than that in the wild type rats.Conclusions Under standard condition,overexpression of bcl-xl could significantly reduce the infarct area and improve neurological function in transgene mice than those in the wild type rats.The effect of overexpression of bcl-xl might be realized through inhibiting the apoptosis of neuron,and the mechanism might be that the overexpression of bcl-xl inhibit the release of cytochrome C and the activation of caspase-3.