2.Investigation of expression of c-erbB-2 and DPC4 in tissues of colonic schistosomiasis and colorectal carcinoma
Kuangsong WANG ; Jifang WEN ; Ming SHEN
Chinese Journal of General Surgery 1993;0(03):-
Objective To determine the relationship between chronic colonic schistosomiasis and colorectal carcinoma.Methods Expression levels of c-erbB-2 and DPC4 were detected by two-step and SP immunohistochemical method respectively in normal colonic mucosa of 15 cases,in colonic mucosa of 15 cases with simple schistosomiasis,20 cases of colorectal carcinoma with schistosomiasis and 20 cases of colorectal carcinoma without schistosomiasis.Results c-erbB-2 was expressed in each group with different levels,but the level in colonic mucosa with schistosomiasis was the highest compared to other groups,which had statistical significance(P
3.Effect of Valproate on Leptin and Serum Lipids in Children with Epilepsy
zhao-chun, WEN ; ru-ming, WANG
Journal of Applied Clinical Pediatrics 2004;0(12):-
Objective To explore the effect of valproate(VPA) on body mass index(BMI),leptin and serum lipids in children with epilepsy.Methods (Twenty-)four cases with epilepsy were selected.BMI and serum levels of leptin,total cholesterol(TC),(triacylgly)-cerol(TG),high density lipoprotein-cholesterin(HDL-C),low density hipoprotein-cholesterin(LDL-C) after treated with VPA for 3 months and 6 months were determined.Results The levels of BMI,leptin,TC,TG,LDL-C after treated 3 months were all significantly higher than those of initial(all P0.05).Those in treated 6 months were same as levels of treated 3 months.Only LDL-C level was lower than that of 3 months and same as level of before treatment.Conclusion VPA do have efficacy to cause obesity in children with epilepsy,and most of the cases occur in the first 3 months after VPA treatment.
4.Risk factors for recurrence of ovarian endometriomas after surgical excision.
Ming, YUAN ; Wen-wen, WANG ; Yan, LI ; Ling, GAO ; Tian, WANG ; Shi-xuan, WANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2014;34(2):213-9
Ovarian endometrioma is a common form of endometriosis, which may cause infertility, dysmenorrhea and pelvic pain in women of reproductive age. Although surgery is the treatment of choice for endometriomas, recurrence poses a formidable frustration. This study investigated potential risk factors of endometriomas recurrence, aiming to better understand its pathogenesis. A total of 307 patients with endometriomas were followed up for an average of 28.6 months and the 1-, 2- and 3-year cumulative recurrence rate was 9.5%, 21.9%, and 29.2%, respectively. Twenty-one potential risk factors for endometriomas recurrence were evaluated using Cox's proportional hazards models. Total revised American Fertility Society (rAFS) score was significantly associated with higher recurrence (OR=1.858, 95% CI=1.122-3.075, P=0.016), as well as younger age at surgery (OR=0.953, 95% CI=0.915-0.992, P=0.020). Semiradical surgical treatment was defined as surgical removal of cyst plus hysterectomy with preservation of bilateral or unilateral ovary, and was a significant factor that was associated with lower recurrence than the conservative surgery (OR=0.318, 95% CI=0.107-0.951, P=0.040). Postoperative pregnancy was favorable factors for disease recurrence (OR=0.217, 95% CI=0.102-0.460, P=0.000). The results suggest that endometrioma recurrence is inversely associated with age at surgery and postoperative pregnancy, and may correlate with total rAFS score and conservative surgery method.
5.Relationship between duodenal diverticula and cannulation time during ERCP procedures and post ERCP complications
Ming WEN ; Jianming WANG ; Qibin HE ; Yiyang ZHANG ; Xiaoping ZOU
Chinese Journal of Digestive Endoscopy 2016;33(8):543-546
Objective To investigate the influence of duodenal diverticula on cannulation time and complication in patients undergoing ERCP.Methods Data of 3 265 patients undergoing ERCP in Drum Tower Hospital affiliated to Nanjing Medical University between January 1,2008 and December 31,2014 were enrolled.The patients' information and endoscopic pictures/videos were collected.The duodenal diverticula,cannulation time,postoperative complications were analyzed.Results There were 2 599 (79.6%) cases of non-diverticula,445(13.6%) cases of one-diverticula,122(3.7%) patients with two or more diverticula,and 99 (3.0%) intradiverticular papilla.Patients with duodenal diverticula accounted for 20.4% (666/3 265) of all patients who received ERCP procedure.The mean cannulation time was 6.62 minutes in all cases,6.30 minutes in non-diverticula group,7.63 minutes in one-diverticula group,8.07 minutes in two-or-more group,8.58 minutes in intradiverticular papilla group,respectively.There were significant differences in cannulation time and complication rate between the groups.Conclusion Duodenal diverticula may be one of the factors that affect the cannulation time.It may enhance the cannulation complications and prolong the cannulation time,especially in those with intradiverticular papilla.
6.Related factors of death in patients with gas burst induced burn.
Lin-hong LIU ; Wen-jie REN ; Ming-jun WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(10):611-613
Adult
;
Burns
;
etiology
;
mortality
;
China
;
epidemiology
;
Coal Mining
;
Explosions
;
Female
;
Gases
;
Humans
;
Male
;
Middle Aged
;
Retrospective Studies
;
Young Adult
7.Clinical analysis of 221 cases of inhalation injury induced by gas explosion.
Lin-hong LIU ; Wen-jie REN ; Ming-jun WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(8):494-495
Adolescent
;
Adult
;
Burns, Inhalation
;
etiology
;
therapy
;
Explosions
;
Female
;
Gases
;
Humans
;
Male
;
Retrospective Studies
;
Young Adult
8.Distribution of types of bacteria involved in infection after burn caused by gas outburst and analysis of drug tolerance.
Wen-jie REN ; Ming-jun WANG ; Song-yue LI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(7):421-423
Adolescent
;
Adult
;
Aged
;
Burns
;
etiology
;
microbiology
;
Child
;
Child, Preschool
;
Drug Resistance, Bacterial
;
Explosions
;
Female
;
Humans
;
Male
;
Middle Aged
;
Wound Infection
;
microbiology
;
Young Adult
10.Field Investigation of Sparganosis in Frogs in Huaxi Area
Jiazhi MAO ; Bijun ZHOU ; Kaigong WANG ; Ming WEN
Chinese Journal of Parasitology and Parasitic Diseases 1987;0(02):-
Frogs were caught from 4 towns in Huaxi of Guiyang and dissected.The collected spargana were used to infect young dogs for species identification.Results showed that the wild frogs were identified as Rana nigromaculata, and the infection rate was 16%(131/818) with an average intensity infection of 3.44 per frog, The tapeworm obtained from an infected dog was specified as Spirometra mansoni.