1.Investigation and analysis on teaching evaluation of professional teachers in military medical university
Juan LU ; Shihao WEN ; Weimin REN
Chinese Journal of Medical Education Research 2005;0(05):-
The course arrangement,teaching contents and means and other items were investigated and analyzed in this research of teaching evaluation of professional teachers in military medical university.The results showed that the levels of post-oriented education teaching were increasing in updating ideas and accumulating experiences in recent years.However,there still existed a few problems such as too much basal theories,lack of real army circs in the contents and little practice in the manners.Therefore,the quality of post-oriented education in military medical university is expected to be developed to a higher level.
3.Recent advances in pericytes angiogenic signaling pathways.
Wen-bao LU ; Xiao-rui SHI ; Rui-juan XIU
Chinese Journal of Pathology 2011;40(6):423-426
Angiopoietins
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metabolism
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physiology
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Animals
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Cell Proliferation
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Endothelial Cells
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cytology
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physiology
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Humans
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Neoplasms
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blood supply
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Neovascularization, Pathologic
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physiopathology
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Neovascularization, Physiologic
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physiology
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Pericytes
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cytology
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metabolism
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physiology
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Proto-Oncogene Proteins c-sis
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metabolism
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physiology
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Receptor, Platelet-Derived Growth Factor beta
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metabolism
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physiology
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Receptor, TIE-2
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metabolism
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physiology
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Signal Transduction
4.CD_4~+ CD_(28)~(null) T cell numbers of peripheral blood in patients with coronary heart diseases
Li-Juan HUANG ; Ying CUI ; Wen-Ying SUN ; Gui-Qin DU ; Lu-Lu LI ;
Chinese Journal of Laboratory Medicine 2001;0(04):-
Objective To investigate changes in CD_4~+ CD_(28)~(null)T cell numbers of peripheral blood and the expression of perforin in patients with coronary heart disease.Methods Sixty-eight patients with acute coronary syndromes,56 with stable angina and 65 healthy subjects were enrolled in the study.CD_4~+ CD_(28)~(null)T lymphocytes were measured by flow cytometric analysis.Results The numbers of CD_4~+ CD_(28)~(null)T lymphocytes in patients with acute coronary syndromes were higher than those in patients with stable angina and in the control subjects(11.6 % vs 2.84% and 0.59%,P
6.Effects of water extraction of Salvia miltiorrhiza in sperm quality of mice
Huanqun ZHOU ; Wen ZHOU ; Shan LU ; Yan XIE ; Aiai WANG ; Juan LIU ; Huifang LIU
The Journal of Practical Medicine 2016;32(20):3342-3345
Objective To research effects of water extraction of Salvia miltiorrhiza in sperm quality of mice. Methods Forty adult male Kunming mice were randomly divided into 5 groups, including low concentration group, medium concentration group, high concentration group, control group and positive control group in eight mice in each group. The low, medium and high concentration groups were given by gavage with 1 500, 3 000 and 6 000 mg/kg water extraction of salvia miltiorrhiza once a day respectively, while the control group was given gavage with 10 mL/kg normal saline daily, as well as the positive control group was injected with 100 mg/kg cyclophosphamide once; All mice were sacrificed after 30 days. We measured the weight gain, viscera coefficient and sperm quality in each mouse. Results There were no statistical difference in the weight of every week, increase of the weight, testis and epididymis coefficients among the control group, the low, medium and high concentration groups (P > 0.05), while the weight and weight increase were significantly higher than that in the positive control group (P < 0.05). Sperm concentration, viability, morphology, motility, PR, VSL, VAP of low, medium and high concentrations group were significantly improved than the control group (P < 0.05), and the sperm quality in the four groups were higher than that in the positive control group (P < 0.05). Conclusion Water extraction of salvia miltiorrhiza can obviously improve the sperm viability, morphology, and motility of mice.
7.The predictive value of serum estradiol level during early phase of controlled ovarian hyperstimulation in IVF-ET
Juan LIU ; Huanqun ZHOU ; Wen ZHOU ; Shan LU ; Yunping NI ; Dongying TANG ; Yijiao CHEN
The Journal of Practical Medicine 2016;32(13):2157-2160
Objective To evaluate the value of serum E2 levels during COH in predicting IVF-ET outcome. Method Data from 311 IVF-ET cycles received long protocol were collected and analyzed according to E 2 levels 5 days after stimulation:Group A (E2≤500 pmol/L), Group B (500
8.Comparison of polymerase chain reaction and bacteria culture in peritoneal dialysis associated peritonitis
Chanyuan WANG ; Yonggui WU ; Xiangming QI ; Juan WANG ; Hong DAI ; Wen LU
Chinese Journal of Nephrology 2015;31(12):898-904
Objective To evaluate clinical application value of polymerase chain reaction (PCR) detection for bacteria in peritoneal dialysis associated peritonitis (PDAP).Methods Peritoneal dialysis fluid specimens were collected from January 2014 to December 2014 in The First Affiliated Hospital of Anhui Medical University.Conventional bacterial culture and PCR detection were used respectively.According to the bacterial 16S rRNA gene, universal primers were devised and designed, based on reference, the specific primers of 17 kinds of experimental bacteria.Real-time fluorescent PCR (Real-time PCR, qPCR) amplification was implemented.The establishment of standard strain DNA extract was used as positive control;sterile double distilled water was used as negative control.Results (1) The traditional bacterial culture results showed that positive proportion was 26/40 in specimen of 40 cases, gram-positive strains accounting for 18/26.Main species were epidermis staphylococcus (5/26), hemolysis staphylococcus (4/26), escherichia coli (4/26), and streptococcus viridans (3/26).(2) The PCR detection results showed that total positive rate was 33/40 in 40 patients specimens, among which 2 cases of positive samples ended up with no specific strains being detected;the main bacteria strains in PCR were not different from ordinary culture results.(3) With bacterial culture as the gold standard, the detection sensitivity of PCR technology for PDAP pathogenic bacteria was 96.15% and specificity was 42.86%;the detection positive rate was significantly higher than ordinary culture method.(4) PCR technology for detecting pathogenic bacteria could produce results within 4-6 hours, while reported positive results in the traditional bacterial culture would take (77.88±15.53) hours, which was significantly longer than PCR.Conclusion Compared with traditional bacteria culture method, PCR method is more sensitive, simple, and quick.Bacteria detection using PCR technique is of clinic applied value in PDRP.
9.Pharmaceutical Care for One Case of Renal Transplantation Recipient with Pulmonary Infection
Guiping GUO ; Yao LU ; Xiangduan LIU ; Xiaoliang QIAN ; Juan BAI ; Aidong WEN ; Yin WU
China Pharmacist 2015;(11):1928-1930
Objective:To provide some thoughts for pharmaceutical treatment and care for the patients with pulmonary infection af-ter renal transplantation. Methods:Clinical pharmacists participated the whole treatment process of one case of pulmonary infection af-ter renal transplantation. According to the literatures combined with medical history, clinical symptoms and lab results, the drug treat-ment process of the patient was analyzed, and the key points of the optimized pharmaceutical care were summarized. Results: The pharmaceutical care included the dose adjustment of immunosuppressants at the early phase of the disease and after the improvement of clinical symptoms, attention paid to the interactions between multiple anti-infective drugs and immunosuppressive agents, dosage ad-justment based on the renal function of the patient, monitoring adverse drug reactions and drawing up personalized regimen. Conclu-sion:Through comprehensive medication monitoring, clinical pharmacists can help physicians develop timely and effective treatment programs and provide professional and effective pharmaceutical care for patients.
10.Predictive Effect of Mean Platelet Volume in Patients with Portal Vein Thrombosis: A Meta-analysis of Case-control Studies
Wen-Yi LIN ; Xuan LU ; Feng-Juan FAN ; Yu HU
Journal of Huazhong University of Science and Technology (Medical Sciences) 2018;38(4):575-581
Mean platelet volume (MPV) is an early marker of platelet activation.Larger platelets,compared to small ones,increase platelet adhesion and aggregation,and present a higher thrombotic activity.Some studies have explored the association between MPV and the morbidity of portal vein thrombosis (PVT).The aim of this study was to evaluate the predictive effect of MPV in patients with PVT by a meta-analysis.We searched Pubmed,Web of Science,SCOPUS,OVID,CNKI and CBMD from database inception to September 13,2017.Seven studies in accordance with selection criteria were included.The extraction of basic data was independently conducted by two reviewers.The mean difference in MPV between PVT patients and controls were pooled with weighted mean difference (WMD)and 95% confidence interval of 0.88 fl (95% CI:0.61-1.15).A random-effect model was chosen for an obvious heterogeneity in the pooling (Chi-square=27.12,df=6,P<0.0001,I2=77.9%).The sources of heterogeneity were from the difference of primary disease of participants and portal vein diameter.Taken together,our results reveal that MPV is a predictive indicator in patients with PVT.